{"id":"https://openalex.org/W2560475969","doi":"https://doi.org/10.1016/j.canlet.2016.11.033","title":"VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis","display_name":"VLDL and LDL, but not HDL, promote breast cancer cell proliferation, metastasis and angiogenesis","publication_year":2016,"publication_date":"2016-12-07","ids":{"openalex":"https://openalex.org/W2560475969","doi":"https://doi.org/10.1016/j.canlet.2016.11.033","mag":"2560475969","pmid":"https://pubmed.ncbi.nlm.nih.gov/27940127"},"language":"en","primary_location":{"id":"doi:10.1016/j.canlet.2016.11.033","doi":"https://doi.org/10.1016/j.canlet.2016.11.033","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.canlet.2016.11.033","pdf_url":null,"source":{"id":"https://openalex.org/S106234763","display_name":"Cancer Letters","issn_l":"0304-3835","issn":["0304-3835","1872-7980"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019213734","display_name":"Chun-Wun Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chun-Wun Lu","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023474952","display_name":"Yi-Hsuan Lo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yi-Hsuan Lo","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038110895","display_name":"Chu\u2010Huang Chen","orcid":"https://orcid.org/0000-0002-1509-7883","observed_orcids":["https://orcid.org/0000-0002-1509-7883"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]},{"id":"https://openalex.org/I4210159511","display_name":"Changhua Christian Hospital","ror":"https://ror.org/05d9dtr71","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210159511"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chu-Huang Chen","raw_affiliation_strings":["Lipid Science and Aging Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan; Lipid and Glycoimmune Research Center, Changhua Christian Hospital, Changhua, Taiwan; Vascular and Medicinal Research, Texas Heart Institute, Houston, TX 77030, USA","Lipid Science and Aging Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan","Lipid and Glycoimmune Research Center, Changhua Christian Hospital, Changhua, Taiwan","Vascular and Medicinal Research, Texas Heart Institute, Houston, TX 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lipid Science and Aging Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan; Lipid and Glycoimmune Research Center, Changhua Christian Hospital, Changhua, Taiwan; Vascular and Medicinal Research, Texas Heart Institute, Houston, TX 77030, USA","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341","https://openalex.org/I4210159511"]},{"raw_affiliation_string":"Lipid Science and Aging Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]},{"raw_affiliation_string":"Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Lipid and Glycoimmune Research Center, Changhua Christian Hospital, Changhua, Taiwan","institution_ids":["https://openalex.org/I4210159511"]},{"raw_affiliation_string":"Vascular and Medicinal Research, Texas Heart Institute, Houston, TX 77030, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101656450","display_name":"Ching\u2010Yi Lin","orcid":"https://orcid.org/0000-0003-2564-1341","observed_orcids":["https://orcid.org/0000-0003-2564-1341"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ching-Yi Lin","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":"https://orcid.org/0000-0003-2564-1341","affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053895813","display_name":"Chun\u2010Hao Tsai","orcid":"https://orcid.org/0000-0002-4428-3132","observed_orcids":["https://orcid.org/0000-0002-4428-3132"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chun-Hao Tsai","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan","Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan","Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]},{"raw_affiliation_string":"Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101517649","display_name":"Po-Jung Chen","orcid":"https://orcid.org/0000-0002-9493-1011","observed_orcids":["https://orcid.org/0000-0002-9493-1011","https://orcid.org/0000-0002-4057-5832"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Po-Jung Chen","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101972949","display_name":"Yi\u2010Fang Yang","orcid":"https://orcid.org/0000-0002-9575-3915","observed_orcids":["https://orcid.org/0000-0002-9575-3915"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yi-Fang Yang","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047216868","display_name":"Chie\u2010Hong Wang","orcid":"https://orcid.org/0000-0003-0774-5323","observed_orcids":["https://orcid.org/0000-0003-0774-5323"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chie-Hong Wang","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":"https://orcid.org/0000-0003-0774-5323","affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065439449","display_name":"Chun\u2010Hsiang Tan","orcid":"https://orcid.org/0000-0001-6950-4678","observed_orcids":["https://orcid.org/0000-0001-6950-4678"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chun-Hsiang Tan","raw_affiliation_strings":["Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006129657","display_name":"Ming\u2010Feng Hou","orcid":"https://orcid.org/0000-0001-6030-9702","observed_orcids":["https://orcid.org/0000-0001-6030-9702"]},"institutions":[{"id":"https://openalex.org/I142974352","display_name":"National Sun Yat-sen University","ror":"https://ror.org/00mjawt10","country_code":"TW","type":"education","lineage":["https://openalex.org/I142974352"]},{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]},{"id":"https://openalex.org/I4210145822","display_name":"Kaohsiung Municipal Hsiao-Kang Hospital","ror":"https://ror.org/04gn22j10","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210145822"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Ming-Feng Hou","raw_affiliation_strings":["Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Division of General and Gastroenterological Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; National Sun Yat-Sen University-Kaohsiung Medical University Joint Research Center, Kaohsiung, Taiwan; Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan. Electronic address: mifeho@kmu.edu.tw","Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan","Division of General and Gastroenterological Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan","Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan","National Sun Yat-Sen University-Kaohsiung Medical University Joint Research Center, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Division of General and Gastroenterological Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; National Sun Yat-Sen University-Kaohsiung Medical University Joint Research Center, Kaohsiung, Taiwan; Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan. Electronic address: mifeho@kmu.edu.tw","institution_ids":["https://openalex.org/I142974352","https://openalex.org/I152743029","https://openalex.org/I2802587341"]},{"raw_affiliation_string":"Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]},{"raw_affiliation_string":"Division of General and Gastroenterological Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]},{"raw_affiliation_string":"Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I4210145822"]},{"raw_affiliation_string":"National Sun Yat-Sen University-Kaohsiung Medical University Joint Research Center, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I142974352","https://openalex.org/I152743029"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073229588","display_name":"Shyng\u2010Shiou F. Yuan","orcid":"https://orcid.org/0000-0002-4753-788X","observed_orcids":["https://orcid.org/0000-0002-4753-788X"]},"institutions":[{"id":"https://openalex.org/I152743029","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96","country_code":"TW","type":"education","lineage":["https://openalex.org/I152743029"]},{"id":"https://openalex.org/I2802587341","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I2802587341"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Shyng-Shiou F. Yuan","raw_affiliation_strings":["Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Obstetrics and Gynecology, Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: 1020005@kmuh.org.tw","Department of Obstetrics and Gynecology, Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan","Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Obstetrics and Gynecology, Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: 1020005@kmuh.org.tw","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]},{"raw_affiliation_string":"Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029"]},{"raw_affiliation_string":"Translational Research Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan","institution_ids":["https://openalex.org/I152743029","https://openalex.org/I2802587341"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5006129657","https://openalex.org/A5073229588"],"corresponding_institution_ids":["https://openalex.org/I142974352","https://openalex.org/I152743029","https://openalex.org/I2802587341","https://openalex.org/I4210145822"],"apc_list":{"value":4960,"currency":"USD","value_usd":4960},"apc_paid":null,"fwci":2.7888,"has_fulltext":false,"cited_by_count":125,"citation_normalized_percentile":{"value":0.89997971,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"388","issue":null,"first_page":"130","last_page":"138"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11308","display_name":"Sphingolipid Metabolism and Signaling","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.6309999823570251},{"id":"https://openalex.org/keywords/very-low-density-lipoprotein","display_name":"VLDL","score":0.7789999842643738},{"id":"https://openalex.org/keywords/low-density-lipoprotein","display_name":"low-density lipoprotein","score":0.6919999718666077},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.972000002861023},{"id":"https://openalex.org/keywords/lipoprotein-subfractions","display_name":"lipoprotein subfractions","score":0.9190000295639038},{"id":"https://openalex.org/keywords/dyslipoproteinemia","display_name":"dyslipoproteinemia","score":0.7670000195503235},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.7689999938011169},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9319999814033508},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.9440000057220459},{"id":"https://openalex.org/keywords/akt-signaling","display_name":"Akt signaling","score":0.8180000185966492},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.9430000185966492},{"id":"https://openalex.org/keywords/slug","display_name":"Slug","score":0.6370000243186951},{"id":"https://openalex.org/keywords/vimentin","display_name":"vimentin","score":0.9070000052452087},{"id":"https://openalex.org/keywords/beta-catenin","display_name":"\u03b2-catenin","score":0.9660000205039978},{"id":"https://openalex.org/keywords/cell-migration-and-invasion","display_name":"cell migration and invasion","score":0.8410000205039978},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.796999990940094},{"id":"https://openalex.org/keywords/angiogenic-factors","display_name":"angiogenic factors","score":0.5},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.4580000042915344}],"concepts":[{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.6849421262741089},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6724871397018433},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.6688137054443359},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5898603200912476},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.5524151921272278},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5086265802383423},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.5002460479736328},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.4366743564605713},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39312267303466797},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37941500544548035},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3369573950767517},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.20880606770515442},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.14213579893112183},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.12141534686088562},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.09984669089317322}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008079","descriptor_name":"Lipoproteins, VLDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008079","descriptor_name":"Lipoproteins, VLDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008079","descriptor_name":"Lipoproteins, VLDL","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009389","descriptor_name":"Neovascularization, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.canlet.2016.11.033","doi":"https://doi.org/10.1016/j.canlet.2016.11.033","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.canlet.2016.11.033","pdf_url":null,"source":{"id":"https://openalex.org/S106234763","display_name":"Cancer Letters","issn_l":"0304-3835","issn":["0304-3835","1872-7980"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Letters","raw_type":"journal-article"},{"id":"pmid:27940127","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27940127","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8299999833106995,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1237909681","display_name":null,"funder_award_id":"KMU-TP103D18","funder_id":"https://openalex.org/F4320322811","funder_display_name":"Kaohsiung Medical University"},{"id":"https://openalex.org/G2086875116","display_name":null,"funder_award_id":"KMUH102-2T07","funder_id":"https://openalex.org/F4320327176","funder_display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital"},{"id":"https://openalex.org/G2111424833","display_name":null,"funder_award_id":"KMU-TP104D17","funder_id":"https://openalex.org/F4320322811","funder_display_name":"Kaohsiung Medical University"},{"id":"https://openalex.org/G4296033577","display_name":null,"funder_award_id":"KMU-DT105008","funder_id":"https://openalex.org/F4320322811","funder_display_name":"Kaohsiung Medical University"},{"id":"https://openalex.org/G6180670340","display_name":null,"funder_award_id":"KMUH103-3R28","funder_id":"https://openalex.org/F4320327176","funder_display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital"},{"id":"https://openalex.org/G6339257976","display_name":null,"funder_award_id":"KMU-DT103010","funder_id":"https://openalex.org/F4320322811","funder_display_name":"Kaohsiung Medical University"},{"id":"https://openalex.org/G6384357214","display_name":null,"funder_award_id":"KMUH104-4R29","funder_id":"https://openalex.org/F4320327176","funder_display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital"},{"id":"https://openalex.org/G7759333143","display_name":null,"funder_award_id":"KMU-DT106004","funder_id":"https://openalex.org/F4320322811","funder_display_name":"Kaohsiung Medical University"}],"funders":[{"id":"https://openalex.org/F4320322811","display_name":"Kaohsiung Medical University","ror":"https://ror.org/03gk81f96"},{"id":"https://openalex.org/F4320327176","display_name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","ror":"https://ror.org/02xmkec90"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1523672843","https://openalex.org/W1964886813","https://openalex.org/W1971377099","https://openalex.org/W1981389215","https://openalex.org/W1982833706","https://openalex.org/W1984063828","https://openalex.org/W1991138100","https://openalex.org/W2001157090","https://openalex.org/W2016409094","https://openalex.org/W2020536190","https://openalex.org/W2021286927","https://openalex.org/W2022650450","https://openalex.org/W2023929299","https://openalex.org/W2023997387","https://openalex.org/W2028169076","https://openalex.org/W2029461689","https://openalex.org/W2031425067","https://openalex.org/W2031540681","https://openalex.org/W2046755317","https://openalex.org/W2047692952","https://openalex.org/W2082878557","https://openalex.org/W2095893831","https://openalex.org/W2117692326","https://openalex.org/W2120875487","https://openalex.org/W2127624416","https://openalex.org/W2128003095","https://openalex.org/W2137944656","https://openalex.org/W2138362890","https://openalex.org/W2138523008","https://openalex.org/W2139739531","https://openalex.org/W2140815756","https://openalex.org/W2143212869","https://openalex.org/W2148187428","https://openalex.org/W2151307659","https://openalex.org/W2153178365","https://openalex.org/W2162884060","https://openalex.org/W2164019843","https://openalex.org/W2176658830","https://openalex.org/W2326415909","https://openalex.org/W2330270710","https://openalex.org/W2340670419","https://openalex.org/W2347999221","https://openalex.org/W2410513590","https://openalex.org/W2477183992","https://openalex.org/W4211223669"],"related_works":["https://openalex.org/W3183179750","https://openalex.org/W2024933597","https://openalex.org/W2070783513","https://openalex.org/W3116479654","https://openalex.org/W4205189596","https://openalex.org/W2916964185","https://openalex.org/W2422815049","https://openalex.org/W2098584395","https://openalex.org/W2982360817","https://openalex.org/W4206939639"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":4}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}