{"id":"https://openalex.org/W2560154550","doi":null,"title":"Effects of chronic sleep restriction on blood vessel density in the prefrontal cortex and hippocampus in rats","display_name":"Effects of chronic sleep restriction on blood vessel density in the prefrontal cortex and hippocampus in rats","publication_year":2016,"publication_date":"2016-12-06","ids":{"openalex":"https://openalex.org/W2560154550","mag":"2560154550"},"language":"en","primary_location":{"id":"pmh:oai:dal.scholaris.ca:10222/72304","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10222/72304","pdf_url":null,"source":{"id":"https://openalex.org/S7407064432","display_name":"DalSpace (Dalhousie University)","issn_l":"2041-2096","issn":["2041-2096"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-a","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/I129902397","host_organization_name":"Dalhousie University","host_organization_lineage":["https://openalex.org/I129902397"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077277090","display_name":"Andrew Baldin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Andrew Baldin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5077277090"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11373","display_name":"Sleep and Work-Related Fatigue","score":0.06509999930858612,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-sleep-restriction","display_name":"chronic sleep restriction","score":0.9959999918937683},{"id":"https://openalex.org/keywords/blood-vessel-density","display_name":"blood vessel density","score":0.9589999914169312},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"prefrontal cortex","score":0.9480000138282776},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":1.0},{"id":"https://openalex.org/keywords/glymphatic-system","display_name":"glymphatic system","score":0.9190000295639038},{"id":"https://openalex.org/keywords/neurovascular-unit","display_name":"neurovascular unit","score":0.48899999260902405},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.5720000267028809},{"id":"https://openalex.org/keywords/sleep-deprivation","display_name":"sleep deprivation","score":0.8230000138282776},{"id":"https://openalex.org/keywords/brain-waste-clearance","display_name":"brain waste clearance","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.7645254135131836},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.7513525485992432},{"id":"https://openalex.org/C2780937657","wikidata":"https://www.wikidata.org/wiki/Q5141192","display_name":"Sleep restriction","level":4,"score":0.6696152687072754},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5369282960891724},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.4557667374610901},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.39334383606910706},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3754814863204956},{"id":"https://openalex.org/C2778329153","wikidata":"https://www.wikidata.org/wiki/Q1364801","display_name":"Sleep deprivation","level":3,"score":0.3278402090072632},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.16503804922103882},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.11662685871124268},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:dal.scholaris.ca:10222/72304","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10222/72304","pdf_url":null,"source":{"id":"https://openalex.org/S7407064432","display_name":"DalSpace (Dalhousie University)","issn_l":"2041-2096","issn":["2041-2096"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-a","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/I129902397","host_organization_name":"Dalhousie University","host_organization_lineage":["https://openalex.org/I129902397"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2560154550","doi":null,"is_oa":false,"landing_page_url":"https://dalspace.library.dal.ca/handle/10222/72304","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":77,"referenced_works":["https://openalex.org/W84689042","https://openalex.org/W95049539","https://openalex.org/W195896834","https://openalex.org/W1567524252","https://openalex.org/W1593453890","https://openalex.org/W1959902108","https://openalex.org/W1969049738","https://openalex.org/W1971125401","https://openalex.org/W1972312480","https://openalex.org/W1972709709","https://openalex.org/W1976856122","https://openalex.org/W1977311786","https://openalex.org/W1989108716","https://openalex.org/W1989231302","https://openalex.org/W1989441555","https://openalex.org/W1993523135","https://openalex.org/W1997672695","https://openalex.org/W2001132720","https://openalex.org/W2008889895","https://openalex.org/W2009755276","https://openalex.org/W2010532243","https://openalex.org/W2010856791","https://openalex.org/W2012675518","https://openalex.org/W2013184659","https://openalex.org/W2013333500","https://openalex.org/W2013714990","https://openalex.org/W2016701600","https://openalex.org/W2021704433","https://openalex.org/W2024955728","https://openalex.org/W2027113588","https://openalex.org/W2038019472","https://openalex.org/W2038318553","https://openalex.org/W2047497650","https://openalex.org/W2048893204","https://openalex.org/W2059061504","https://openalex.org/W2062235618","https://openalex.org/W2068021881","https://openalex.org/W2068607973","https://openalex.org/W2070155357","https://openalex.org/W2073209134","https://openalex.org/W2075341996","https://openalex.org/W2075808524","https://openalex.org/W2077970463","https://openalex.org/W2081325363","https://openalex.org/W2088355263","https://openalex.org/W2088948024","https://openalex.org/W2089572539","https://openalex.org/W2092001446","https://openalex.org/W2092616115","https://openalex.org/W2094500507","https://openalex.org/W2101478912","https://openalex.org/W2102024835","https://openalex.org/W2104827963","https://openalex.org/W2110157711","https://openalex.org/W2112251383","https://openalex.org/W2112772389","https://openalex.org/W2117678477","https://openalex.org/W2117743783","https://openalex.org/W2125954178","https://openalex.org/W2127460667","https://openalex.org/W2130941610","https://openalex.org/W2131575045","https://openalex.org/W2140012616","https://openalex.org/W2144705128","https://openalex.org/W2146976930","https://openalex.org/W2150645528","https://openalex.org/W2153762265","https://openalex.org/W2154494913","https://openalex.org/W2156897439","https://openalex.org/W2163225965","https://openalex.org/W2167183660","https://openalex.org/W2169079203","https://openalex.org/W2225591226","https://openalex.org/W2237013884","https://openalex.org/W2432018567","https://openalex.org/W2530840165","https://openalex.org/W2538734062"],"related_works":["https://openalex.org/W1990996033","https://openalex.org/W4206619577","https://openalex.org/W4390928583","https://openalex.org/W3047298563","https://openalex.org/W3022500555","https://openalex.org/W7120593893","https://openalex.org/W4394961827","https://openalex.org/W4402661788","https://openalex.org/W4405287733","https://openalex.org/W4410504078"],"abstract_inverted_index":{"Increased":[0],"blood":[1,29,83,94,123],"vessel":[2,30,95,124],"density":[3,31,96],"could":[4],"increase":[5,66,79,101],"the":[6,9,16,21,37,71,74,114,136,144,147],"efficiency":[7,145],"of":[8,50,90,111,120,146],"glymphatic":[10,148],"system":[11],"which":[12],"removes":[13],"waste":[14],"from":[15],"brain.":[17],"This":[18],"study":[19],"tested":[20],"hypothesis":[22],"that":[23,133],"chronic":[24],"sleep":[25,43],"restriction":[26],"(CSR)":[27],"increases":[28],"in":[32,58,80,102],"brain":[33],"regions,":[34],"such":[35,69],"as":[36,70],"prefrontal":[38,75],"cortex,":[39,76],"where":[40,61],"wake":[41],"and":[42],"deprivation":[44],"are":[45],"associated":[46],"with":[47],"higher":[48],"levels":[49],"neuronal":[51,62],"activity":[52,63],"compared":[53],"to":[54],"sleep,":[55],"but":[56],"not":[57,65,98],"those":[59],"regions":[60],"does":[64],"during":[67],"wake,":[68],"hippocampus.":[72],"In":[73,113],"a":[77,140],"small":[78],"newly":[81,103],"grown":[82,104],"vessels":[84,105],"was":[85,117],"observed":[86],"after":[87,107],"four":[88],"days":[89],"CSR":[91,121,134],"while":[92],"total":[93],"did":[97],"increase.":[99],"No":[100],"occurred":[106],"4":[108],"four-day":[109],"cycles":[110],"CSR.":[112],"hippocampus,":[115],"there":[116],"no":[118],"effect":[119,142],"on":[122,127,143],"density.":[125],"Based":[126],"these":[128],"results,":[129],"it":[130],"is":[131],"unlikely":[132],"under":[135],"current":[137],"condition":[138],"has":[139],"major":[141],"system.":[149]},"counts_by_year":[],"updated_date":"2026-09-09T07:26:56.047234","created_date":"2016-12-16T00:00:00"}