{"id":"https://openalex.org/W2557742476","doi":null,"title":"Comparisons of All-Cause Mortality for Chronic Benign Pain Patients Prescribed NSAIDs only, Opiates or Opiates and Adjuvants","display_name":"Comparisons of All-Cause Mortality for Chronic Benign Pain Patients Prescribed NSAIDs only, Opiates or Opiates and Adjuvants","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2557742476","mag":"2557742476"},"language":"en","primary_location":{"id":"pmh:oai:etd.ohiolink.edu:ucin1406900022","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","pdf_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087555137","display_name":"David Charles Randolph","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David Charles Randolph","raw_affiliation_strings":["University of Cincinnati**"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Cincinnati**","institution_ids":["https://openalex.org/I63135867"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5087555137"],"corresponding_institution_ids":["https://openalex.org/I63135867"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.9449999928474426},{"id":"https://openalex.org/keywords/chronic-non-cancer-pain","display_name":"chronic non-cancer pain","score":0.9789999723434448},{"id":"https://openalex.org/keywords/nonsteroidal-anti-inflammatory-drugs","display_name":"nonsteroidal anti-inflammatory drugs","score":0.949999988079071},{"id":"https://openalex.org/keywords/opioid-adjuvants","display_name":"opioid adjuvants","score":0.7170000076293945},{"id":"https://openalex.org/keywords/muscle-relaxants","display_name":"muscle relaxants","score":0.9430000185966492},{"id":"https://openalex.org/keywords/antidepressants","display_name":"antidepressants","score":0.9980000257492065},{"id":"https://openalex.org/keywords/workers-compensation","display_name":"workers' compensation","score":0.9210000038146973},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.5370000004768372},{"id":"https://openalex.org/keywords/relative-risk","display_name":"relative risk","score":0.5289999842643738},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.8040000200271606},{"id":"https://openalex.org/keywords/emergency-department-visits","display_name":"emergency department visits","score":0.7490000128746033},{"id":"https://openalex.org/keywords/opioid-prescribing-guidelines","display_name":"opioid prescribing guidelines","score":0.3400000035762787},{"id":"https://openalex.org/keywords/pain-management-policy","display_name":"pain management policy","score":0.32499998807907104}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8292925357818604},{"id":"https://openalex.org/C2781118164","wikidata":"https://www.wikidata.org/wiki/Q1088113","display_name":"Chronic pain","level":2,"score":0.4429892301559448},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38407236337661743},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.34444713592529297},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.15586283802986145}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:etd.ohiolink.edu:ucin1406900022","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","pdf_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","raw_type":"text"},{"id":"mag:2557742476","doi":null,"is_oa":false,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etd.ohiolink.edu:ucin1406900022","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","pdf_url":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406900022","raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2557742476.pdf","grobid_xml":"https://content.openalex.org/works/W2557742476.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W31280369","https://openalex.org/W1506104687","https://openalex.org/W1599185368","https://openalex.org/W1846770152","https://openalex.org/W1847547405","https://openalex.org/W1969612617","https://openalex.org/W1970516435","https://openalex.org/W1979990272","https://openalex.org/W1980316389","https://openalex.org/W1982248155","https://openalex.org/W1993335225","https://openalex.org/W1998690451","https://openalex.org/W1999600197","https://openalex.org/W2003262321","https://openalex.org/W2009383738","https://openalex.org/W2015232020","https://openalex.org/W2015565638","https://openalex.org/W2023243818","https://openalex.org/W2025506163","https://openalex.org/W2034713111","https://openalex.org/W2046027935","https://openalex.org/W2048292736","https://openalex.org/W2050977476","https://openalex.org/W2053440173","https://openalex.org/W2066553562","https://openalex.org/W2069119834","https://openalex.org/W2069877006","https://openalex.org/W2072409292","https://openalex.org/W2080943234","https://openalex.org/W2097089198","https://openalex.org/W2100905521","https://openalex.org/W2103725359","https://openalex.org/W2104216897","https://openalex.org/W2107662809","https://openalex.org/W2113431190","https://openalex.org/W2115095782","https://openalex.org/W2115702982","https://openalex.org/W2122160984","https://openalex.org/W2125488472","https://openalex.org/W2132791572","https://openalex.org/W2134234269","https://openalex.org/W2134506621","https://openalex.org/W2143187686","https://openalex.org/W2143221646","https://openalex.org/W2144897778","https://openalex.org/W2148043055","https://openalex.org/W2149191413","https://openalex.org/W2150505499","https://openalex.org/W2157242687","https://openalex.org/W2158152684","https://openalex.org/W2160172135","https://openalex.org/W2160997565","https://openalex.org/W2167069418","https://openalex.org/W2168330913","https://openalex.org/W2169426067","https://openalex.org/W2170147223","https://openalex.org/W2170465719","https://openalex.org/W2312966816"],"related_works":["https://openalex.org/W6939748716","https://openalex.org/W3043268834","https://openalex.org/W2521235289","https://openalex.org/W2429408914","https://openalex.org/W2515215995","https://openalex.org/W3127658513","https://openalex.org/W6977098730","https://openalex.org/W6939640635","https://openalex.org/W4410398451","https://openalex.org/W2515348598"],"abstract_inverted_index":{"of":[0,4,35,55,98,161,170,209,221,232,239,250,266,270,275,295,303,318],"Background":[1],"Data:":[2],"Trends":[3],"increasing":[5],"mortality":[6,57],"with":[7,18,25,74,282],"prescription":[8],"opiate":[9],"use":[10,274],"have":[11,38,189,218,247],"been":[12,40],"reported":[13,41],"in":[14,42,72,102,268,288],"multiple":[15],"publications.In":[16],"populations":[17],"CNMP,":[19],"adjuvant":[20,77],"medications":[21,78,204,261,281],"are":[22,113,118,172,205,212,236,263],"commonly":[23,75],"combined":[24],"opiates":[26,64,122,129,135,151,244,287],"to":[27,80,106,115,180,321],"decrease":[28],"symptoms":[29],"and/or":[30,136,138,140,152,156,279],"side":[31],"effects.Studies":[32],"evaluating":[33],"ACM":[34,171,248,267],"these":[36,271,319],"combinations":[37],"not":[39,206],"a":[43,94,291],"workers'":[44,60,99],"compensation":[45,61,100],"population":[46,101],"Objective:":[47],"To":[48],"determine":[49],"the":[50,190,230,327],"relative":[51],"risk":[52,165,168,294,302],"and":[53,71,126,132,146,148,166,201,229,242,259,284,310],"predictors":[54,208,238,265],"all-cause":[56],"(ACM)":[58],"among":[59],"patients":[62,111,184],"prescribed":[63,119,213,262],"for":[65,174,193,326],"chronic":[66],"non-malignant":[67],"pain":[68],"(CNMP)":[69],"alone":[70],"combination":[73,289],"utilized":[76],"compared":[79,114],"those":[81],"taking":[82,185],"NSAIDs":[83,181],"only.Methods:":[84],"A":[85],"h":[86],"i":[87,92],"s":[88],"t":[89],"o":[90],"r":[91],"c":[93],"l":[95],"cohort":[96],"study":[97],"Ohio":[103],"from":[104],"01/01/2000":[105],"06/10/2011":[107],"was":[108],"conducted.NSAIDs":[109],"only":[110,123,182,245],"(controls)":[112],"cases":[116],"who":[117,211],"short":[120,125,131,147,283],"acting":[121,128,134,150,286],"(SA),":[124],"long":[127,133,149,285],"(SLO),":[130],"anxiolytic":[137],"sedative":[139],"hypnotic":[141,280],"medication":[142,176],"(SLO":[143,158],"+":[144,159,187,215],"ASH),":[145],"any":[153,276],"muscle":[154],"relaxers":[155],"antidepressants":[157],"MR/AD).Outcome":[160],"interest":[162],"is":[163,305],"ACM.Relative":[164],"adjusted":[167],"factors":[169],"presented":[173],"each":[175],"group.Results:":[177],"When":[178],"comparing":[179],"subjects,":[183],"SLO":[186,214,241,309],"ASH":[188],"highest":[191],"RR":[192,223,249],"death,":[194],"3.22":[195],"(95%":[196,225,252,256],"CI,":[197,226,253,257],"1.60-6.94).Age,":[198],"sex,":[199],"dose":[200],"duration":[202],"on":[203],"significant":[207,237,264,292,301],"mortality.Patients":[210],"MR/AD":[216,311],"also":[217],"increased":[219,293],"risks":[220,320],"mortality,":[222],"1.73":[224],"1.15-2.59).Age,":[227],"sex":[228],"number":[231],"emergency":[233],"room":[234],"visits":[235],"ACM.iii":[240],"SA":[243],"groups":[246],"1.57":[251],"0.92-2.71)and":[254],"1.23":[255],"0.89-1.69)respectively.Age":[258],"total":[260],"both":[269],"groups.Conclusion:":[272],"The":[273],"anxiolytic,":[277],"sedative,":[278],"poses":[290],"ACM.A":[296],"lesser,":[297],"but":[298],"still":[299],"highly":[300],"death":[304],"noted":[306],"when":[307],"combining":[308],"medications.Health":[312],"care":[313,325],"providers":[314],"should":[315],"be":[316],"aware":[317],"provide":[322],"safe":[323],"medical":[324],"injured":[328],"workers.iv":[329]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-12-08T00:00:00"}
