{"id":"https://openalex.org/W2557531334","doi":"https://doi.org/10.1186/s12937-016-0217-2","title":"An overview on the role of dietary phenolics for the treatment of cancers","display_name":"An overview on the role of dietary phenolics for the treatment of cancers","publication_year":2016,"publication_date":"2016-11-30","ids":{"openalex":"https://openalex.org/W2557531334","doi":"https://doi.org/10.1186/s12937-016-0217-2","mag":"2557531334","pmid":"https://pubmed.ncbi.nlm.nih.gov/27903278","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5131407"},"language":"en","primary_location":{"id":"doi:10.1186/s12937-016-0217-2","doi":"https://doi.org/10.1186/s12937-016-0217-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12937-016-0217-2","pdf_url":"https://nutritionj.biomedcentral.com/track/pdf/10.1186/s12937-016-0217-2","source":{"id":"https://openalex.org/S134899435","display_name":"Nutrition Journal","issn_l":"1475-2891","issn":["1475-2891"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition Journal","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://nutritionj.biomedcentral.com/track/pdf/10.1186/s12937-016-0217-2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025672513","display_name":"Preethi G. Anantharaju","orcid":"https://orcid.org/0000-0001-7842-8929","observed_orcids":["https://orcid.org/0000-0001-7842-8929"]},"institutions":[{"id":"https://openalex.org/I126824641","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191","country_code":"IN","type":"education","lineage":["https://openalex.org/I126824641"]},{"id":"https://openalex.org/I86826812","display_name":"JSS Medical College and Hospital","ror":"https://ror.org/02xf0fd83","country_code":"IN","type":"education","lineage":["https://openalex.org/I86826812"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Preethi G. Anantharaju","raw_affiliation_strings":["Department of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India","institution_ids":["https://openalex.org/I126824641","https://openalex.org/I86826812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025138435","display_name":"C Prathima","orcid":"https://orcid.org/0000-0003-4261-883X","observed_orcids":["https://orcid.org/0000-0003-4261-883X"]},"institutions":[{"id":"https://openalex.org/I126824641","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191","country_code":"IN","type":"education","lineage":["https://openalex.org/I126824641"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prathima C. Gowda","raw_affiliation_strings":["Department of Pharmacology, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India","institution_ids":["https://openalex.org/I126824641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042579368","display_name":"Manjunath Gubbanna Vimalambike","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126824641","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191","country_code":"IN","type":"education","lineage":["https://openalex.org/I126824641"]},{"id":"https://openalex.org/I86826812","display_name":"JSS Medical College and Hospital","ror":"https://ror.org/02xf0fd83","country_code":"IN","type":"education","lineage":["https://openalex.org/I86826812"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manjunatha G. Vimalambike","raw_affiliation_strings":["Department of Pathology, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India","institution_ids":["https://openalex.org/I126824641","https://openalex.org/I86826812"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007749446","display_name":"SubbaRao V. Madhunapantula","orcid":"https://orcid.org/0000-0001-9167-9271","observed_orcids":["https://orcid.org/0000-0001-9167-9271"]},"institutions":[{"id":"https://openalex.org/I126824641","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191","country_code":"IN","type":"education","lineage":["https://openalex.org/I126824641"]},{"id":"https://openalex.org/I86826812","display_name":"JSS Medical College and Hospital","ror":"https://ror.org/02xf0fd83","country_code":"IN","type":"education","lineage":["https://openalex.org/I86826812"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"SubbaRao V. Madhunapantula","raw_affiliation_strings":["Department of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India. madhunapantulas@yahoo.com","Department of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India. madhunapantulas@yahoo.com","institution_ids":["https://openalex.org/I126824641","https://openalex.org/I86826812"]},{"raw_affiliation_string":"Department of Biochemistry, Center of Excellence in Molecular Biology and Regenerative Medicine, JSS Medical College, JSS University, Mysore, 570 015, Karnataka, India","institution_ids":["https://openalex.org/I126824641","https://openalex.org/I86826812"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5007749446"],"corresponding_institution_ids":["https://openalex.org/I126824641","https://openalex.org/I86826812"],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":{"value":3190,"currency":"USD","value_usd":3190},"fwci":2.2638,"has_fulltext":true,"cited_by_count":537,"citation_normalized_percentile":{"value":0.89754098,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"15","issue":"1","first_page":"99","last_page":"99"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dietary-phenolic-compounds","display_name":"dietary phenolic compounds","score":0.7760000228881836},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.7480000257492065},{"id":"https://openalex.org/keywords/tumor-cell-death","display_name":"cancer cell death","score":0.6480000019073486},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.9330000281333923},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.7329999804496765},{"id":"https://openalex.org/keywords/nf-kb","display_name":"NF-kB","score":0.7229999899864197},{"id":"https://openalex.org/keywords/nrf2","display_name":"Nrf2","score":0.9259999990463257},{"id":"https://openalex.org/keywords/stat-transcription-factors","display_name":"STAT transcription factors","score":0.7730000019073486},{"id":"https://openalex.org/keywords/histone-deacetylase","display_name":"histone deacetylase","score":0.9829999804496765},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.7409999966621399},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9829999804496765},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9129999876022339},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7649999856948853},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C124320809","wikidata":"https://www.wikidata.org/wiki/Q46292","display_name":"Cyclin-dependent kinase","level":4,"score":0.5926143527030945},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5605970621109009},{"id":"https://openalex.org/C2777609662","wikidata":"https://www.wikidata.org/wiki/Q416356","display_name":"PTEN","level":4,"score":0.5292144417762756},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.49448251724243164},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.4730721414089203},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.46310967206954956},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.4536229968070984},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39785319566726685},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3958430588245392},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.3178967535495758},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.31629273295402527},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.29030275344848633}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009753","descriptor_name":"Nutritive Value","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D064209","descriptor_name":"Phytochemicals","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1186/s12937-016-0217-2","doi":"https://doi.org/10.1186/s12937-016-0217-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12937-016-0217-2","pdf_url":"https://nutritionj.biomedcentral.com/track/pdf/10.1186/s12937-016-0217-2","source":{"id":"https://openalex.org/S134899435","display_name":"Nutrition Journal","issn_l":"1475-2891","issn":["1475-2891"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition Journal","raw_type":"journal-article"},{"id":"pmid:27903278","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27903278","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition journal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5131407","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5131407/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutr J","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12937-016-0217-2","doi":"https://doi.org/10.1186/s12937-016-0217-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12937-016-0217-2","pdf_url":"https://nutritionj.biomedcentral.com/track/pdf/10.1186/s12937-016-0217-2","source":{"id":"https://openalex.org/S134899435","display_name":"Nutrition Journal","issn_l":"1475-2891","issn":["1475-2891"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320719","display_name":"Department of Science and Technology, Ministry of Science and Technology, India","ror":"https://ror.org/0101xrq71"},{"id":"https://openalex.org/F4320328620","display_name":"Vision Group on Science and Technology","ror":"https://ror.org/052zwa538"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2557531334.pdf","grobid_xml":"https://content.openalex.org/works/W2557531334.grobid-xml"},"referenced_works_count":157,"referenced_works":["https://openalex.org/W88937860","https://openalex.org/W125989078","https://openalex.org/W135858013","https://openalex.org/W137687401","https://openalex.org/W170407616","https://openalex.org/W173405199","https://openalex.org/W205739606","https://openalex.org/W765788331","https://openalex.org/W904058290","https://openalex.org/W1221431759","https://openalex.org/W1484811165","https://openalex.org/W1491459594","https://openalex.org/W1494453148","https://openalex.org/W1509029337","https://openalex.org/W1516101636","https://openalex.org/W1545215516","https://openalex.org/W1551806602","https://openalex.org/W1587195034","https://openalex.org/W1669175391","https://openalex.org/W1691015430","https://openalex.org/W1869064315","https://openalex.org/W1877134362","https://openalex.org/W1897129911","https://openalex.org/W1914679235","https://openalex.org/W1932498841","https://openalex.org/W1964052049","https://openalex.org/W1965015336","https://openalex.org/W1965606785","https://openalex.org/W1970482286","https://openalex.org/W1973168828","https://openalex.org/W1978272694","https://openalex.org/W1979812712","https://openalex.org/W1980591003","https://openalex.org/W1984159955","https://openalex.org/W1986148830","https://openalex.org/W1989043850","https://openalex.org/W1990293840","https://openalex.org/W1994295724","https://openalex.org/W1994657003","https://openalex.org/W1996165453","https://openalex.org/W1999697169","https://openalex.org/W2005153503","https://openalex.org/W2005334224","https://openalex.org/W2007132794","https://openalex.org/W2007942591","https://openalex.org/W2008620949","https://openalex.org/W2008757142","https://openalex.org/W2010185799","https://openalex.org/W2014001117","https://openalex.org/W2014086416","https://openalex.org/W2014361480","https://openalex.org/W2014613601","https://openalex.org/W2016140316","https://openalex.org/W2022481874","https://openalex.org/W2023536393","https://openalex.org/W2025438351","https://openalex.org/W2025682006","https://openalex.org/W2026439698","https://openalex.org/W2029364635","https://openalex.org/W2029722773","https://openalex.org/W2029775714","https://openalex.org/W2029832645","https://openalex.org/W2030749349","https://openalex.org/W2032440171","https://openalex.org/W2034141196","https://openalex.org/W2037024229","https://openalex.org/W2038073816","https://openalex.org/W2042040184","https://openalex.org/W2042932165","https://openalex.org/W2043133793","https://openalex.org/W2048657818","https://openalex.org/W2052920392","https://openalex.org/W2052960809","https://openalex.org/W2054265689","https://openalex.org/W2055022115","https://openalex.org/W2058122973","https://openalex.org/W2060320036","https://openalex.org/W2062172769","https://openalex.org/W2063346783","https://openalex.org/W2065405147","https://openalex.org/W2066774498","https://openalex.org/W2067670322","https://openalex.org/W2068732881","https://openalex.org/W2070242992","https://openalex.org/W2078403611","https://openalex.org/W2080304600","https://openalex.org/W2083768226","https://openalex.org/W2084046958","https://openalex.org/W2084299658","https://openalex.org/W2085167150","https://openalex.org/W2085589102","https://openalex.org/W2085748209","https://openalex.org/W2086868423","https://openalex.org/W2089233520","https://openalex.org/W2091047906","https://openalex.org/W2091269995","https://openalex.org/W2093688795","https://openalex.org/W2095142150","https://openalex.org/W2095754263","https://openalex.org/W2095969086","https://openalex.org/W2100052188","https://openalex.org/W2102582532","https://openalex.org/W2105447906","https://openalex.org/W2106188989","https://openalex.org/W2112312798","https://openalex.org/W2114768416","https://openalex.org/W2114959070","https://openalex.org/W2116060738","https://openalex.org/W2117692326","https://openalex.org/W2122341467","https://openalex.org/W2122530843","https://openalex.org/W2122694669","https://openalex.org/W2123541095","https://openalex.org/W2125648408","https://openalex.org/W2126386203","https://openalex.org/W2127284798","https://openalex.org/W2128217748","https://openalex.org/W2129133439","https://openalex.org/W2132268436","https://openalex.org/W2132297564","https://openalex.org/W2134628298","https://openalex.org/W2137762121","https://openalex.org/W2138664383","https://openalex.org/W2142700519","https://openalex.org/W2144318297","https://openalex.org/W2144660326","https://openalex.org/W2145947053","https://openalex.org/W2146470803","https://openalex.org/W2146572998","https://openalex.org/W2146582448","https://openalex.org/W2147026669","https://openalex.org/W2148073787","https://openalex.org/W2148291330","https://openalex.org/W2153841213","https://openalex.org/W2158944838","https://openalex.org/W2161080185","https://openalex.org/W2163188200","https://openalex.org/W2163388941","https://openalex.org/W2164984533","https://openalex.org/W2165596895","https://openalex.org/W2168389275","https://openalex.org/W2168629112","https://openalex.org/W2202819904","https://openalex.org/W2216409493","https://openalex.org/W2253355615","https://openalex.org/W2311464408","https://openalex.org/W2315835039","https://openalex.org/W2358247965","https://openalex.org/W2358887765","https://openalex.org/W2404681107","https://openalex.org/W2413537610","https://openalex.org/W2889743241","https://openalex.org/W3023923910","https://openalex.org/W4211254291","https://openalex.org/W4237910213","https://openalex.org/W4252280335","https://openalex.org/W6622161800"],"related_works":["https://openalex.org/W1240291967","https://openalex.org/W4295135697","https://openalex.org/W6976629869","https://openalex.org/W4307269008","https://openalex.org/W3003385877","https://openalex.org/W2084046958","https://openalex.org/W4399892188","https://openalex.org/W2516417294","https://openalex.org/W2951168484","https://openalex.org/W3203403249"],"abstract_inverted_index":{"Plant":[0],"derived":[1],"phenolic":[2,110,127,135,160,189,211,226,241,263,282],"compounds":[3,111,128,136,161,212,283],"have":[4,54,157,183,233,251],"been":[5,235],"shown":[6,184],"to":[7,197,225,255],"inhibit":[8],"the":[9,45,109,113,130,138,185,193,207,258,273,277],"initiation":[10],"and":[11,31,35,38,65,76,88,94,96,102,122,129,152,180,284,290],"progression":[12],"of":[13,26,33,48,115,140,187,209,262,279,281],"cancers":[14],"by":[15,287],"modulating":[16],"genes":[17],"regulating":[18],"key":[19,259],"processes":[20],"such":[21,62,84,205],"as:":[22],"(a)":[23,58,256],"oncogenic":[24,59,107],"transformation":[25,163,286],"normal":[27],"cells;":[28],"(b)":[29,67,271],"growth":[30,216],"development":[32],"tumors;":[34],"(c)":[36,81],"angiogenesis":[37],"metastasis.":[39],"Recent":[40],"studies":[41,156,182],"focusing":[42],"on":[43],"identifying":[44],"molecular":[46],"basis":[47],"plant":[49,126,188,210],"phenolics-induced":[50],"cancer":[51,194],"cell":[52,68,149],"death":[53],"demonstrated":[55,158],"down-regulation":[56],"of:":[57],"survival":[60,151],"kinases":[61],"as":[63,85,204],"PI3K":[64],"Akt;":[66],"proliferation":[69],"regulators":[70],"that":[71,159,171],"include":[72],"Erk1/2,":[73],"D-type":[74],"Cyclins,":[75],"Cyclin":[77],"Dependent":[78],"Kinases":[79],"(CDKs);":[80],"transcription":[82],"factors":[83,99],"NF-k\u03b2,":[86],"NRF2":[87],"STATs;":[89],"(d)":[90],"histone":[91],"deacetylases":[92],"HDAC1":[93],"HDAC2;":[95],"(e)":[97],"angiogenic":[98],"VEGF,":[100],"FGFR1":[101],"MIC-1.":[103],"Furthermore,":[104,154],"while":[105],"inhibiting":[106,214],"proteins,":[108],"elevate":[112],"expression":[114],"tumor":[116,215],"suppressor":[117],"proteins":[118],"p53,":[119],"PTEN,":[120],"p21,":[121],"p27.":[123],"In":[124,176],"addition,":[125],"herbal":[131],"extracts":[132],"rich":[133,228],"in":[134,145,164,191,217,223],"modulate":[137],"levels":[139],"reactive":[141],"oxygen":[142],"species":[143],"(ROS)":[144],"cells":[146],"thereby":[147,167],"regulate":[148],"proliferation,":[150],"apoptosis.":[153],"recent":[155],"undergo":[162],"gut":[165,288],"microbiota":[166],"acquire":[168],"additional":[169],"properties":[170],"promote":[172],"their":[173,285],"biological":[174],"activities.":[175],"vitro":[177],"observations,":[178],"preclinical":[179],"epidemiological":[181],"involvement":[186],"acids":[190,242,264],"retarding":[192],"growth.":[195],"However,":[196],"date,":[198],"there":[199],"is":[200],"no":[201],"clinical":[202],"trial":[203],"testing":[206],"role":[208],"for":[213,246,266],"humans.":[218],"More":[219],"over,":[220],"several":[221],"variations":[222],"response":[224],"acid":[227],"diets-mediated":[229],"treatment":[230],"among":[231],"individuals":[232],"also":[234],"reported,":[236],"raising":[237],"concerns":[238],"about":[239,276],"whether":[240],"could":[243],"be":[244],"used":[245],"treating":[247],"cancers.":[248],"Therefore,":[249],"we":[250],"made":[252],"an":[253],"attempt":[254],"address":[257],"structural":[260],"features":[261],"required":[265],"exhibiting":[267],"potent":[268],"anti-cancer":[269],"activity;":[270],"review":[272],"reported":[274],"findings":[275],"mechanisms":[278],"action":[280],"microbiota;":[289]},"counts_by_year":[{"year":2026,"cited_by_count":45},{"year":2025,"cited_by_count":50},{"year":2024,"cited_by_count":75},{"year":2023,"cited_by_count":56},{"year":2022,"cited_by_count":95},{"year":2021,"cited_by_count":60},{"year":2020,"cited_by_count":54},{"year":2019,"cited_by_count":43},{"year":2018,"cited_by_count":37},{"year":2017,"cited_by_count":22}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-12-08T00:00:00"}
