{"id":"https://openalex.org/W2556797668","doi":"https://doi.org/10.1002/9780470514733.ch5","title":"Molecular Biology of Somatostatin Receptors","display_name":"Molecular Biology of Somatostatin Receptors","publication_year":2007,"publication_date":"2007-09-28","ids":{"openalex":"https://openalex.org/W2556797668","doi":"https://doi.org/10.1002/9780470514733.ch5","mag":"2556797668","pmid":"https://pubmed.ncbi.nlm.nih.gov/7587653"},"language":"en","primary_location":{"id":"doi:10.1002/9780470514733.ch5","doi":"https://doi.org/10.1002/9780470514733.ch5","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9780470514733.ch5","pdf_url":null,"source":{"id":"https://openalex.org/S9764341","display_name":"Novartis Foundation symposium","issn_l":"1528-2511","issn":["1528-2511","1935-4657"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Novartis Foundation Symposia","raw_type":"other"},"volume":{"id":"https://openalex.org/W2483983810","display_name":"Ciba Foundation Symposium 190 \u2010 Somatostatin and its Receptors"},"type":"other","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103544018","display_name":"Graeme I. Bell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Graeme I. Bell","raw_affiliation_strings":["Howard Hughes Medical Institute, University of Chicago, IL 60637, USA","Howard Hughes Medical Institute and Departments of Biochemistry and Molecular Biology, and Medicine, The University of Chicago, 5841 S Maryland Avenue, MC 1028, Chicago, IL 60637, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, University of Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I40347166"]},{"raw_affiliation_string":"Howard Hughes Medical Institute and Departments of Biochemistry and Molecular Biology, and Medicine, The University of Chicago, 5841 S Maryland Avenue, MC 1028, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089470172","display_name":"Kazuki Yasuda","orcid":"https://orcid.org/0000-0002-6966-496X","observed_orcids":["https://orcid.org/0000-0002-6966-496X"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kazuki Yasuda","raw_affiliation_strings":["Howard Hughes Medical Institute and Departments of Biochemistry and Molecular Biology, and Medicine, The University of Chicago, 5841 S Maryland Avenue, MC 1028, Chicago, IL 60637, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute and Departments of Biochemistry and Molecular Biology, and Medicine, The University of Chicago, 5841 S Maryland Avenue, MC 1028, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107440475","display_name":"Haeyoung Kong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haeyoung Kong","raw_affiliation_strings":["Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105774745","display_name":"Susan F. Law","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan F. Law","raw_affiliation_strings":["Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109897344","display_name":"Karen Raynor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen Raynor","raw_affiliation_strings":["Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086196539","display_name":"Terry Reisine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terry Reisine","raw_affiliation_strings":["Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Pennsylvania School of Medicine, 36th Street and Hamilton Walk, Philadelphia, PA 19104-6084, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"190","issue":null,"first_page":"65","last_page":"88"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.323199987411499,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.323199987411499,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.2888000011444092,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.28610000014305115,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/somatostatin-receptors","display_name":"somatostatin receptors","score":1.0},{"id":"https://openalex.org/keywords/g-protein-coupled-receptors","display_name":"G protein-coupled receptors","score":0.902999997138977},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.8330000042915344},{"id":"https://openalex.org/keywords/receptor-expression-patterns","display_name":"receptor expression patterns","score":0.6370000243186951},{"id":"https://openalex.org/keywords/somatostatin-analogs","display_name":"somatostatin analogues","score":0.9039999842643738},{"id":"https://openalex.org/keywords/growth-hormone-secretion","display_name":"growth hormone secretion","score":0.8389999866485596},{"id":"https://openalex.org/keywords/insulin-secretion","display_name":"insulin secretion","score":0.9200000166893005},{"id":"https://openalex.org/keywords/gene-cloning","display_name":"gene cloning","score":0.5189999938011169}],"concepts":[{"id":"https://openalex.org/C150008808","wikidata":"https://www.wikidata.org/wiki/Q18031731","display_name":"Somatostatin receptor 2","level":4,"score":0.9325881600379944},{"id":"https://openalex.org/C80115893","wikidata":"https://www.wikidata.org/wiki/Q2067077","display_name":"Somatostatin receptor","level":3,"score":0.9212820529937744},{"id":"https://openalex.org/C64980429","wikidata":"https://www.wikidata.org/wiki/Q18031730","display_name":"Somatostatin receptor 1","level":5,"score":0.8979498147964478},{"id":"https://openalex.org/C32363146","wikidata":"https://www.wikidata.org/wiki/Q18031732","display_name":"Somatostatin receptor 3","level":5,"score":0.7643043994903564},{"id":"https://openalex.org/C2776297358","wikidata":"https://www.wikidata.org/wiki/Q407166","display_name":"Somatostatin","level":2,"score":0.757692813873291},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6684295535087585},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6064426898956299},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.43408477306365967},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4137343764305115},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3523693382740021},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.27719584107398987}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017481","descriptor_name":"Receptors, Somatostatin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017481","descriptor_name":"Receptors, Somatostatin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017481","descriptor_name":"Receptors, Somatostatin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/9780470514733.ch5","doi":"https://doi.org/10.1002/9780470514733.ch5","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9780470514733.ch5","pdf_url":null,"source":{"id":"https://openalex.org/S9764341","display_name":"Novartis Foundation symposium","issn_l":"1528-2511","issn":["1528-2511","1935-4657"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Novartis Foundation Symposia","raw_type":"other"},{"id":"pmid:7587653","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7587653","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ciba Foundation symposium","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G227280380","display_name":null,"funder_award_id":"MH45533","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G2807054497","display_name":null,"funder_award_id":"DK 20595","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6302922443","display_name":"FUNCTIONAL PROPERTIES OF BRAIN SOMATOSTATIN RECEPTORS","funder_award_id":"R01MH048518","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6613230812","display_name":"BIOCHEMICAL PROPERTIES OF SOMATOSTATIN RECEPTORS","funder_award_id":"R01MH045533","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W198959245","https://openalex.org/W597918840","https://openalex.org/W1481622600","https://openalex.org/W1486077694","https://openalex.org/W1508892952","https://openalex.org/W1523852353","https://openalex.org/W1544651836","https://openalex.org/W1556881006","https://openalex.org/W1577531302","https://openalex.org/W1594960037","https://openalex.org/W1604700543","https://openalex.org/W1606588479","https://openalex.org/W1614576580","https://openalex.org/W1619707557","https://openalex.org/W1762236896","https://openalex.org/W1845264055","https://openalex.org/W1887163060","https://openalex.org/W1925289812","https://openalex.org/W1937350043","https://openalex.org/W1947952978","https://openalex.org/W1965710144","https://openalex.org/W1967368337","https://openalex.org/W1967643351","https://openalex.org/W1967886547","https://openalex.org/W1970539039","https://openalex.org/W1971286515","https://openalex.org/W1972789318","https://openalex.org/W1973706463","https://openalex.org/W1977847069","https://openalex.org/W1979139070","https://openalex.org/W1981326638","https://openalex.org/W1982044447","https://openalex.org/W1983853358","https://openalex.org/W1984918402","https://openalex.org/W1992284590","https://openalex.org/W1992866100","https://openalex.org/W1994671985","https://openalex.org/W1995027065","https://openalex.org/W1995347382","https://openalex.org/W1998767852","https://openalex.org/W2004133692","https://openalex.org/W2005342628","https://openalex.org/W2009549035","https://openalex.org/W2014556427","https://openalex.org/W2019763706","https://openalex.org/W2024251022","https://openalex.org/W2027999483","https://openalex.org/W2028882320","https://openalex.org/W2035520173","https://openalex.org/W2039911916","https://openalex.org/W2040887234","https://openalex.org/W2040894153","https://openalex.org/W2056315084","https://openalex.org/W2057065980","https://openalex.org/W2058484249","https://openalex.org/W2062519124","https://openalex.org/W2063230128","https://openalex.org/W2073140573","https://openalex.org/W2073295308","https://openalex.org/W2073466411","https://openalex.org/W2076561683","https://openalex.org/W2077054785","https://openalex.org/W2081174960","https://openalex.org/W2082819145","https://openalex.org/W2084087648","https://openalex.org/W2087547235","https://openalex.org/W2092481738","https://openalex.org/W2093780093","https://openalex.org/W2118631824","https://openalex.org/W2121272721","https://openalex.org/W2124330263","https://openalex.org/W2127058478","https://openalex.org/W2306210109","https://openalex.org/W2398993657","https://openalex.org/W2411268197","https://openalex.org/W2413517490","https://openalex.org/W2442741688","https://openalex.org/W2949435001"],"related_works":["https://openalex.org/W2028792535","https://openalex.org/W1552578597","https://openalex.org/W2066524003","https://openalex.org/W1981326638","https://openalex.org/W2118631824","https://openalex.org/W4251555468","https://openalex.org/W2472221713","https://openalex.org/W1887163060","https://openalex.org/W1968318988","https://openalex.org/W2113568919"],"abstract_inverted_index":{"The":[0,23,45,73,176,251],"diverse":[1,269],"physiological":[2],"effects":[3,270],"of":[4,11,28,75,88,98,115,123,127,144,151,167,183,224,227,240,248,257,271],"somatostatin":[5,17,24,47,159,178,229,259,272],"are":[6,26,71,82,125,132],"mediated":[7],"by":[8,134],"a":[9,128,263],"family":[10,161,261],"cell":[12],"surface":[13],"receptors":[14,25,48,179],"that":[15,236],"bind":[16],"selectively":[18],"and":[19,35,67,92,107,113,131,139,147,190,200,213,244,254],"with":[20,60,137],"high":[21],"affinity.":[22],"members":[27],"the":[29,76,89,104,116,142,145,158,165,186,225,258,268],"seven":[30,77],"transmembrane":[31],"segment":[32],"receptor":[33,160,260],"superfamily":[34],"molecular":[36,252],"cloning":[37,253],"studies":[38,223,232],"have":[39,100,180,194,203,215],"identified":[40,102,217],"five":[41,177],"types,":[42],"designated":[43],"sstr1-5.":[44],"human":[46],"vary":[49],"in":[50,103,111,185,198,221,266],"size":[51,112],"from":[52,164,173],"364":[53],"(sstr5)":[54],"to":[55,202,233],"418":[56],"(sstr3)":[57],"amino":[58,62,69],"acids":[59,70],"46-61%":[61],"acid":[63],"identity":[64],"between":[65],"receptors,":[66],"105":[68],"invariant.":[72],"sequences":[74],"putative":[78],"alpha-helical":[79],"membrane-spanning":[80],"domains":[81],"more":[83],"highly":[84],"conserved":[85],"than":[86],"those":[87],"extracellular":[90],"N-":[91],"intracellular":[93,117],"C-terminal":[94,118],"domains.":[95],"Two":[96],"forms":[97,122],"sstr2":[99,124,152,237],"been":[101,196,216],"mouse,":[105],"sstr2A":[106,138],"sstr2B,":[108],"which":[109,218],"differ":[110],"sequence":[114],"domain.":[119],"These":[120],"two":[121],"products":[126,143],"common":[129],"gene":[130],"generated":[133],"alternative":[135,174],"splicing":[136],"sstr2B":[140],"being":[141],"unspliced":[146],"spliced":[148],"forms,":[149],"respectively,":[150],"mRNA.":[153],"Thus,":[154],"functional":[155,255],"diversity":[156],"within":[157],"may":[162],"result":[163],"expression":[166,184],"multiple":[168],"types":[169],"as":[170,172],"well":[171],"splicing.":[175],"distinct":[181],"patterns":[182],"central":[187],"nervous":[188],"system":[189],"peripheral":[191],"tissues.":[192],"They":[193],"also":[195],"expressed":[197],"vitro":[199],"shown":[201],"different":[204],"pharmacological":[205],"properties.":[206],"Somatostatin":[207],"analogues":[208],"selective":[209],"for":[210],"sstr2,":[211],"sstr3":[212],"sstr5":[214,245],"will":[219],"facilitate":[220],"vivo":[222],"functions":[226],"these":[228],"receptors.":[230],"Such":[231],"date":[234],"suggest":[235],"mediates":[238,246],"inhibition":[239,247],"growth":[241],"hormone":[242],"secretion":[243],"insulin":[249],"secretion.":[250],"characterization":[256],"is":[262],"first":[264],"step":[265],"elucidating":[267],"on":[273],"cellular":[274],"functions.":[275]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-11-30T00:00:00"}