{"id":"https://openalex.org/W2556442500","doi":null,"title":"Engineering Riboswitches: An Insight to the Cell Ci rcuit","display_name":"Engineering Riboswitches: An Insight to the Cell Ci rcuit","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2556442500","mag":"2556442500"},"language":"en","primary_location":{"id":"mag:2556442500","doi":null,"is_oa":false,"landing_page_url":"http://jakraya.com/journal/download.php?file=2-bbbArticle_1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054968869","display_name":"Prasanta Kumar Koustasa Mishra","orcid":"https://orcid.org/0000-0001-8595-8784","observed_orcids":["https://orcid.org/0000-0001-8595-8784"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Prasanta Kumar Koustasa Mishra","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8595-8784","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112226229","display_name":"Amit Ranjan Sahu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amit Ranjan Sahu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101908795","display_name":"Aditya Vikram Agarwal","orcid":"https://orcid.org/0000-0001-9260-0799","observed_orcids":["https://orcid.org/0000-0001-9260-0799"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aditya Vikram Agarwal","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9260-0799","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058478620","display_name":"Manish Mahawar","orcid":"https://orcid.org/0000-0001-9175-5326","observed_orcids":["https://orcid.org/0000-0001-9175-5326"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Manish Mahawar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9175-5326","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/riboswitches","display_name":"riboswitches","score":0.984000027179718},{"id":"https://openalex.org/keywords/rna-engineering","display_name":"RNA engineering","score":0.5910000205039978},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5479999780654907},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.8190000057220459},{"id":"https://openalex.org/keywords/5-untranslated-region","display_name":"5' untranslated region","score":0.7950000166893005},{"id":"https://openalex.org/keywords/aptamers","display_name":"aptamers","score":0.5960000157356262},{"id":"https://openalex.org/keywords/ligand-binding","display_name":"ligand binding","score":0.9350000023841858},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.7400000095367432},{"id":"https://openalex.org/keywords/rna-tertiary-structure","display_name":"RNA tertiary structure","score":0.5059999823570251},{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"synthetic biology","score":0.3799999952316284}],"concepts":[{"id":"https://openalex.org/C148625055","wikidata":"https://www.wikidata.org/wiki/Q418840","display_name":"Riboswitch","level":5,"score":0.9742274284362793},{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.7704874277114868},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6555870771408081},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5933640003204346},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5129725337028503},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5095841884613037},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4451587498188019},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4392664432525635},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4179793894290924},{"id":"https://openalex.org/C194993378","wikidata":"https://www.wikidata.org/wiki/Q427087","display_name":"Non-coding RNA","level":4,"score":0.38291069865226746},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35725563764572144},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3498923182487488},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34400105476379395}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2556442500","doi":null,"is_oa":false,"landing_page_url":"http://jakraya.com/journal/download.php?file=2-bbbArticle_1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1519084876","https://openalex.org/W1611625030","https://openalex.org/W1972708527","https://openalex.org/W1976851914","https://openalex.org/W1980045457","https://openalex.org/W1998214904","https://openalex.org/W2010173857","https://openalex.org/W2016430241","https://openalex.org/W2021774273","https://openalex.org/W2030621944","https://openalex.org/W2041999156","https://openalex.org/W2054546131","https://openalex.org/W2054613021","https://openalex.org/W2061930808","https://openalex.org/W2067258168","https://openalex.org/W2088892367","https://openalex.org/W2090247088","https://openalex.org/W2106769579","https://openalex.org/W2121665468","https://openalex.org/W2125952821","https://openalex.org/W2131841865","https://openalex.org/W2132920850","https://openalex.org/W2140524006","https://openalex.org/W2144548050","https://openalex.org/W2150147498","https://openalex.org/W2215023125"],"related_works":["https://openalex.org/W4413176751","https://openalex.org/W3124452157","https://openalex.org/W1997852106","https://openalex.org/W7017984563","https://openalex.org/W2072917294","https://openalex.org/W4407475199","https://openalex.org/W1887652822","https://openalex.org/W2150147498","https://openalex.org/W2915936948","https://openalex.org/W2083750892"],"abstract_inverted_index":{"Riboswitches":[0],"are":[1],"the":[2,75,90],"naturally":[3],"occurring":[4],"RNA":[5,82],"molecules":[6,13],"that":[7],"can":[8,84],"bind":[9],"to":[10,74],"various":[11,33,54],"small":[12],"by":[14,32,53,72,78],"their":[15,70],"secondary":[16],"and":[17],"tertiary":[18],"structures.":[19],"This":[20],"cis-acting":[21],"elements":[22],"present":[23],"at":[24],"5'":[25],"UTR":[26],"of":[27],"mRNA":[28],"regulates":[29],"gene":[30,37],"expression":[31],"mechanisms.":[34],"Though":[35],"mostly":[36],"regulation":[38],"via":[39],"riboswitches":[40],"is":[41],"a":[42,86],"post":[43],"transcriptional":[44],"phenomenon":[45],"b":[46],"ut":[47],"it":[48],"also":[49],"exhibits":[50],"its":[51],"function":[52],"other":[55],"molecular":[56,66],"pathways.":[57],"Vario":[58],"us":[59],"ligands":[60],"have":[61],"been":[62],"discovered":[63],"for":[64,89],"these":[65,81],"switches":[67],"which":[68],"execute":[69],"functions":[71],"binding":[73],"aptamer":[76],"formed":[77],"riboswitches.":[79],"Modifying":[80],"platforms":[83],"be":[85],"promising":[87],"area":[88],"cutting":[91],"e":[92],"dge":[93],"technology":[94],"in":[95],"cell":[96],"biology":[97],"as":[98,100],"well":[99],"biotechnology.":[101]},"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-11-30T00:00:00"}