{"id":"https://openalex.org/W2554069186","doi":"https://doi.org/10.1002/mds.26864","title":"Anhidrosis in multiple system atrophy involves pre\u2010 and postganglionic sudomotor dysfunction","display_name":"Anhidrosis in multiple system atrophy involves pre\u2010 and postganglionic sudomotor dysfunction","publication_year":2016,"publication_date":"2016-11-10","ids":{"openalex":"https://openalex.org/W2554069186","doi":"https://doi.org/10.1002/mds.26864","mag":"2554069186","pmid":"https://pubmed.ncbi.nlm.nih.gov/27859565","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5483990"},"language":"en","primary_location":{"id":"doi:10.1002/mds.26864","doi":"https://doi.org/10.1002/mds.26864","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mds.26864","pdf_url":null,"source":{"id":"https://openalex.org/S163027424","display_name":"Movement Disorders","issn_l":"0885-3185","issn":["0885-3185","1531-8257"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Movement Disorders","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5483990","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027274949","display_name":"Elizabeth A. Coon","orcid":"https://orcid.org/0000-0003-1206-0222","observed_orcids":["https://orcid.org/0000-0003-1206-0222"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth A. Coon","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058330394","display_name":"Robert D. Fealey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert D. Fealey","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070408627","display_name":"David M. Sletten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David M. Sletten","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003255743","display_name":"Jay N. Mandrekar","orcid":"https://orcid.org/0000-0002-9718-4082","observed_orcids":["https://orcid.org/0000-0002-9718-4082"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jay N. Mandrekar","raw_affiliation_strings":["Department of Clinical Statistics, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Statistics, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069111019","display_name":"Eduardo Elias Benarroch","orcid":"https://orcid.org/0000-0001-7968-5054","observed_orcids":["https://orcid.org/0000-0001-7968-5054"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eduardo E. Benarroch","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070172721","display_name":"Paola Sandroni","orcid":"https://orcid.org/0000-0001-7618-9661","observed_orcids":["https://orcid.org/0000-0001-7618-9661"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paola Sandroni","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047373167","display_name":"Phillip A. Low","orcid":"https://orcid.org/0000-0002-5386-4764","observed_orcids":["https://orcid.org/0000-0002-5386-4764"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Phillip A. Low","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086023917","display_name":"Wolfgang Singer","orcid":"https://orcid.org/0000-0003-1263-6850","observed_orcids":["https://orcid.org/0000-0003-1263-6850"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wolfgang Singer","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086023917"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":3.8778,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.93694214,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"32","issue":"3","first_page":"397","last_page":"404"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11109","display_name":"Thermoregulation and physiological responses","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12625","display_name":"Sympathectomy and Hyperhidrosis Treatments","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-system-atrophy","display_name":"multiple system atrophy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/anhidrosis","display_name":"anhidrosis","score":0.9850000143051147},{"id":"https://openalex.org/keywords/sudomotor-dysfunction","display_name":"sudomotor dysfunction","score":0.996999979019165},{"id":"https://openalex.org/keywords/thermoregulatory-sweat-test","display_name":"thermoregulatory sweat test","score":0.9319999814033508},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.7329999804496765},{"id":"https://openalex.org/keywords/autonomic-dysfunction","display_name":"autonomic dysfunction","score":0.8029999732971191}],"concepts":[{"id":"https://openalex.org/C2778638887","wikidata":"https://www.wikidata.org/wiki/Q7633918","display_name":"Sudomotor","level":2,"score":0.925357460975647},{"id":"https://openalex.org/C63398376","wikidata":"https://www.wikidata.org/wiki/Q7395168","display_name":"SWEAT","level":2,"score":0.7222135066986084},{"id":"https://openalex.org/C2776525014","wikidata":"https://www.wikidata.org/wiki/Q1531991","display_name":"Parkinsonism","level":3,"score":0.6874296069145203},{"id":"https://openalex.org/C2781172350","wikidata":"https://www.wikidata.org/wiki/Q194520","display_name":"Atrophy","level":2,"score":0.5940196514129639},{"id":"https://openalex.org/C2779203496","wikidata":"https://www.wikidata.org/wiki/Q545408","display_name":"Anhidrosis","level":2,"score":0.5740261077880859},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4638189673423767},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.41131338477134705},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38593411445617676},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.1874520480632782},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.05278995633125305}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001342","descriptor_name":"Autonomic Nervous System Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001342","descriptor_name":"Autonomic Nervous System Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D001342","descriptor_name":"Autonomic Nervous System Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002526","descriptor_name":"Cerebellar Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007007","descriptor_name":"Hypohidrosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007007","descriptor_name":"Hypohidrosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D007007","descriptor_name":"Hypohidrosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019578","descriptor_name":"Multiple System Atrophy","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D020734","descriptor_name":"Parkinsonian Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1002/mds.26864","doi":"https://doi.org/10.1002/mds.26864","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mds.26864","pdf_url":null,"source":{"id":"https://openalex.org/S163027424","display_name":"Movement Disorders","issn_l":"0885-3185","issn":["0885-3185","1531-8257"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Movement Disorders","raw_type":"journal-article"},{"id":"pmid:27859565","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27859565","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Movement disorders : official journal of the Movement Disorder Society","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4330048","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5483990","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5483990","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5483990","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Mov Disord","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4330048","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5483990","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1365584847","display_name":"Pathogenesis and Diagnosis of Multiple System Atrophy (P01)","funder_award_id":"P01NS044233","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3015807127","display_name":"Mayo Clinic Center for Clinical and Translational Science (CCaTS)","funder_award_id":"UL1TR000135","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3308772956","display_name":null,"funder_award_id":"R01 FD004789","funder_id":"https://openalex.org/F4320332163","funder_display_name":"U.S. Food and Drug Administration"},{"id":"https://openalex.org/G5101366154","display_name":null,"funder_award_id":"NS4 4233","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7163101906","display_name":null,"funder_award_id":"R01 FD004789","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7360870831","display_name":"Autonomic Rare Diseases Clinical Research Consortium","funder_award_id":"U54NS065736","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8259063287","display_name":"Differential Approach to the Postural Tachycardia Syndrome","funder_award_id":"K23NS075141","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000901472","display_name":"Synucleinopathies \u2013 Novel Targets in Early Diagnosis, Pathophysiology, and Therapeutic Approach","funder_award_id":"R01NS092625","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1839521047","https://openalex.org/W1968174397","https://openalex.org/W1986080761","https://openalex.org/W1991087865","https://openalex.org/W1991297141","https://openalex.org/W2004355019","https://openalex.org/W2011540686","https://openalex.org/W2012445753","https://openalex.org/W2018726083","https://openalex.org/W2044663328","https://openalex.org/W2047992148","https://openalex.org/W2066874389","https://openalex.org/W2080854251","https://openalex.org/W2085383007","https://openalex.org/W2087911691","https://openalex.org/W2091287531","https://openalex.org/W2106865131","https://openalex.org/W2133313651","https://openalex.org/W2133688632","https://openalex.org/W2151455166","https://openalex.org/W2155299862","https://openalex.org/W2155457768","https://openalex.org/W2161125327","https://openalex.org/W2163240050","https://openalex.org/W2166522195","https://openalex.org/W2194258549","https://openalex.org/W2429413516","https://openalex.org/W2614974832","https://openalex.org/W7074198534"],"related_works":["https://openalex.org/W2205290260","https://openalex.org/W2151455166","https://openalex.org/W4206667832","https://openalex.org/W2080854251","https://openalex.org/W2429413516","https://openalex.org/W2047992148","https://openalex.org/W3120909317","https://openalex.org/W3164179517","https://openalex.org/W2038162242","https://openalex.org/W2562001392"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,80,155,171,190],"objective":[2],"of":[3,17,39,82,106,136,157,192,226,245,253],"this":[4],"study":[5],"was":[6,94,102,160,177],"to":[7,26,114],"characterize":[8],"the":[9,83,158,242,261],"degree,":[10],"pattern,":[11],"lesion":[12,62,159],"site,":[13],"and":[14,25,32,48,54,61,75,130,152,164,167,212,216,235,240,268],"temporal":[15],"evolution":[16],"sudomotor":[18,52,77,92,194,204,247],"dysfunction":[19,205,248],"in":[20,96,104,162,169,173,210,218,231,260],"multiple":[21],"system":[22],"atrophy":[23],"(MSA)":[24],"evaluate":[27],"differences":[28],"by":[29],"parkinsonian":[30],"(MSA-parkinsonism)":[31],"cerebellar":[33],"(MSA-cerebellar)":[34],"subtypes.":[35],"METHODS:":[36],"All":[37],"cases":[38],"MSA":[40,211],"evaluated":[41],"at":[42],"Mayo":[43],"Clinic":[44],"Rochester":[45],"between":[46],"2005":[47],"2010":[49],"with":[50,122,140],"postganglionic":[51,76,91,193,236,246,254],"testing":[53,93],"thermoregulatory":[55,72,99,118,183],"sweat":[56,73,100,119,184,227,257],"test":[57,74,101,120],"were":[58,68,86,111,149],"reviewed.":[59],"Pattern":[60],"site":[63,156],"(preganglionic,":[64],"postganglionic,":[65],"or":[66,256],"mixed)":[67],"determined":[69],"based":[70,179],"on":[71,180,187],"testing.":[78],"RESULTS:":[79],"majority":[81],"232":[84],"patients":[85,110],"MSA-parkinsonism":[87,109,219],"(145,":[88],"63%).":[89],"Initial":[90],"abnormal":[95,103,117],"59%,":[97],"whereas":[98],"95%":[105],"all":[107],"patients.":[108,189],"more":[112,214],"likely":[113],"have":[115],"an":[116],"compared":[121,139],"MSA-cerebellar":[123,141],"(98%":[124],"versus":[125],"90%,":[126],"P":[127,143],"=":[128,144],"0.006)":[129],"had":[131],"a":[132,223],"higher":[133],"mean":[134],"percentage":[135],"anhidrosis":[137,147,174],"(57%)":[138],"(48%;":[142],"0.033).":[145],"Common":[146],"patterns":[148],"regional":[150],"(38%)":[151],"global":[153],"(35%).":[154],"preganglionic":[161,224],"47%":[163],"mixed":[165],"(preganglionic":[166],"postganglionic)":[168],"41%.":[170],"increase":[172],"per":[175],"year":[176],"6.2%":[178],"70":[181],"repeat":[182],"tests":[185],"performed":[186],"29":[188],"frequency":[191,244],"abnormalities":[195,237],"increased":[196],"over":[197,249],"time.":[198],"CONCLUSIONS:":[199],"Our":[200],"findings":[201],"suggest:":[202],"(1)":[203],"is":[206,229],"almost":[207],"invariably":[208],"present":[209],"even":[213],"common":[215,230],"severe":[217],"than":[220],"MSA-cerebellar;":[221],"(2)":[222],"pattern":[225],"loss":[228],"MSA;":[232],"however,":[233],"pre-":[234],"may":[238],"coexist;":[239],"(3)":[241],"increasing":[243],"time":[250],"suggests":[251],"involvement":[252],"fibers":[255],"glands":[258],"later":[259],"disease":[262],"course.":[263],"\u00a9":[264],"2016":[265],"International":[266],"Parkinson":[267],"Movement":[269],"Disorder":[270],"Society.":[271]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-11-30T00:00:00"}