{"id":"https://openalex.org/W2553831317","doi":null,"title":"Effect of Some Levels of Cardamom, Clove and Anise on Hepatotoxicity in Rats Caused by CCL 4","display_name":"Effect of Some Levels of Cardamom, Clove and Anise on Hepatotoxicity in Rats Caused by CCL 4","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2553831317","mag":"2553831317"},"language":"en","primary_location":{"id":"mag:2553831317","doi":null,"is_oa":false,"landing_page_url":"http://www.idosi.org/wasj/wasj33(6)15/1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066885489","display_name":"Shimaa M. H. Aboelnaga","orcid":"https://orcid.org/0000-0002-7580-2281","observed_orcids":["https://orcid.org/0000-0002-7580-2281"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Shimaa M. H. Aboelnaga","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7580-2281","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5066885489"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9356,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.71181324,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12756","display_name":"Plant Toxicity and Pharmacological Properties","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardamom","display_name":"cardamom","score":0.9229999780654907},{"id":"https://openalex.org/keywords/syzygium-aromaticum","display_name":"Syzygium aromaticum","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anise","display_name":"anise","score":1.0},{"id":"https://openalex.org/keywords/hepatotoxicity","display_name":"hepatotoxicity","score":0.9440000057220459},{"id":"https://openalex.org/keywords/carbon-tetrachloride","display_name":"carbon tetrachloride","score":0.984000027179718},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.6380000114440918},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.7950000166893005},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.9070000052452087},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.7820000052452087},{"id":"https://openalex.org/keywords/blood-chemistry","display_name":"serum biochemistry","score":0.7329999804496765},{"id":"https://openalex.org/keywords/hepatoprotective-effect","display_name":"hepatoprotection","score":0.6579999923706055},{"id":"https://openalex.org/keywords/spices","display_name":"spices","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.6822713613510132},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.49820756912231445},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4847950041294098},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.47713446617126465},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.4635659158229828},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.36260655522346497},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3360905647277832},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.329781174659729},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29740357398986816},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.07299476861953735}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2553831317","doi":null,"is_oa":false,"landing_page_url":"http://www.idosi.org/wasj/wasj33(6)15/1.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4388615071","https://openalex.org/W3122287889","https://openalex.org/W4403652863","https://openalex.org/W4392621117","https://openalex.org/W4411819931","https://openalex.org/W2991499420","https://openalex.org/W3111477505","https://openalex.org/W3019264169","https://openalex.org/W2102204402","https://openalex.org/W4411680503"],"abstract_inverted_index":{"The":[0,41,57,192,310],"aim":[1],"of":[2,10,13,115,167,326,333,348],"this":[3,33,334],"study":[4,335],"was":[5,125,199],"to":[6,142,201,254],"investigate":[7],"the":[8,35,75,93,112,116,121,149,154,165,168,171,177,184,190,255,262,276,318,323,331],"effect":[9],"three":[11,277],"levels":[12,278],"cardamom,":[14,73],"clove":[15,281,327],"and":[16,43,54,60,71,78,89,96,107,157,181,183,197,214,228,235,245,282,289,340,345],"anise":[17,341],"on":[18,47,65,83,101,211,258],"rats":[19,27,36,172,178,210,256,270],"suffering":[20],"from":[21,189,273,279],"hepatotoxicity.":[22],"Fifty":[23],"five":[24],"male":[25],"albino":[26],"(Sprague":[28],"Dawley":[29],"Strain)":[30],"used":[31],"in":[32,131,146,224,261,313],"study,":[34],"divided":[37],"into":[38],"eleven":[39],"groups.":[40,56],"first":[42,263],"second":[44],"groups":[45,62,80,98],"fed":[46,64,82,100,226,257],"basal":[48,66,84,102,212,259],"diet":[49,67,85,103,213,260],"as":[50,252],"a":[51,136],"control":[52,123],"negative":[53,122,267],"positive":[55,219],"third,":[58],"fourth":[59],"fifth":[61],"were":[63,81,99,160,173,179,187,195],"containing":[68,86,104],"(2%,":[69,87,105],"4%":[70,88,106],"6%":[72,90,108],"respectively),":[74,92],"sixth,":[76],"seventh":[77],"eighth":[79],"clove,":[91,338],"ninth,":[94],"tenth":[95],"eleventh":[97],"anise,":[109],"respectively).":[110],"On":[111],"27":[113],"day":[114],"experiment,":[117],"all":[118],"animals,":[119],"except":[120,242],"group":[124,265,319],"administered":[126],"subcutaneous":[127],"injection":[128],"20%":[129],"CCl":[130,217],"liquid":[132],"paraffin":[133],"oil":[134],"at":[135,164],"dose":[137],"5":[138],"ml/kg":[139],"body":[140,158,229,285],"weight":[141,230,286],"induce":[143],"4":[144,225],"hepatotoxicity":[145,274,347],"rats.":[147,349],"During":[148],"experimental":[150],"period":[151],"(28":[152],"days),":[153],"diets":[155],"consumed":[156],"weights":[159],"recorded":[161,316],"twice":[162],"weekly,":[163],"end":[166],"experiment":[169],"period,":[170],"fasted":[174],"overnight,":[175],"then":[176],"anaesthetized":[180],"sacrificed":[182],"blood":[185,193],"samples":[186,194],"collected":[188],"aorta.":[191],"centrifuged":[196],"serum":[198,293],"separated":[200],"determine":[202],"some":[203],"biochemical":[204],"parameters.":[205],"Results":[206],"showed":[207],"that,":[208],"feeding":[209],"injected":[215],"with":[216,275,322],"(control":[218,266],"group)":[220],"induced":[221],"non-significant":[222],"changes":[223],"intake":[227],"gain":[231],"%,":[232],"while":[233,307],"liver":[234,238,288],"kidney":[236,246,290],"weights,":[237],"enzymes,":[239],"lipid":[240],"profile,":[241],"HDL-c,":[243],"glucose":[244],"functions":[247],"increased":[248,342],"significantly":[249],"increase":[250],"p?0.5,":[251],"compared":[253],"main":[264],"group).":[268],"Treating":[269],"which":[271,320],"suffer":[272],"(cardamom,":[280],"anise)":[283],"decreased":[284],"gain%,":[287],"weights/body":[291],"weight%,":[292],"AST,":[294],"ALT,":[295],"ALP,":[296],"cholesterol,":[297],"triglycerides,":[298],"LDL-c,":[299],"VLDL-c,":[300],"uric":[301],"acid,":[302],"urea":[303],"nitrogen,":[304],"creatinine,":[305],"glucose,":[306],"HDL-c":[308],"increased.":[309],"highest":[311],"improvement":[312],"these":[314],"parameters":[315],"for":[317],"treated":[321],"high":[324],"level":[325],"(6%).":[328],"In":[329],"conclusion,":[330],"results":[332],"demonstrate":[336],"that":[337],"cardamom":[339],"antioxidant":[343],"activity":[344],"improved":[346]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3}],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-11-30T00:00:00"}
