{"id":"https://openalex.org/W25535467","doi":null,"title":"Mass spectrometry-based high throughput approach for identification of molecular modification of oxidative process in respiratory diseases.","display_name":"Mass spectrometry-based high throughput approach for identification of molecular modification of oxidative process in respiratory diseases.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W25535467","mag":"25535467"},"language":"en","primary_location":{"id":"pmh:oai:engagedscholarship.csuohio.edu:etdarchive-1276","doi":null,"is_oa":true,"landing_page_url":"https://engagedscholarship.csuohio.edu/etdarchive/277","pdf_url":"https://engagedscholarship.csuohio.edu/cgi/viewcontent.cgi?article=1276&context=etdarchive","source":{"id":"https://openalex.org/S4306400889","display_name":"EngagedScholarship @ Cleveland State University (Cleveland State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102607778","host_organization_name":"Cleveland State University","host_organization_lineage":["https://openalex.org/I102607778"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ETD Archive","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://engagedscholarship.csuohio.edu/cgi/viewcontent.cgi?article=1276&context=etdarchive","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020877144","display_name":"Wei Song","orcid":"https://orcid.org/0000-0002-4973-7236","observed_orcids":["https://orcid.org/0000-0002-4973-7236"]},"institutions":[{"id":"https://openalex.org/I102607778","display_name":"Cleveland State University","ror":"https://ror.org/002tx1f22","country_code":"US","type":"education","lineage":["https://openalex.org/I102607778"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wei Song","raw_affiliation_strings":["Cleveland State University"],"raw_orcid":"https://orcid.org/0000-0002-4973-7236","affiliations":[{"raw_affiliation_string":"Cleveland State University","institution_ids":["https://openalex.org/I102607778"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5020877144"],"corresponding_institution_ids":["https://openalex.org/I102607778"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00227907,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.3970000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.3970000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.2705000042915344,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.08590000122785568,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eosinophil-peroxidase","display_name":"eosinophil peroxidase","score":0.9160000085830688},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/protein-oxidation","display_name":"protein oxidation","score":0.7139999866485596},{"id":"https://openalex.org/keywords/stable-isotope-dilution","display_name":"stable isotope dilution","score":0.7879999876022339},{"id":"https://openalex.org/keywords/lc-esi-ms-ms","display_name":"LC-ESI-MS/MS","score":0.7599999904632568},{"id":"https://openalex.org/keywords/high-throughput-analysis","display_name":"high-throughput analysis","score":0.6610000133514404},{"id":"https://openalex.org/keywords/respiratory-diseases","display_name":"respiratory diseases","score":0.7210000157356262},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.5910000205039978},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.6650000214576721},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8059437870979309},{"id":"https://openalex.org/C2776923573","wikidata":"https://www.wikidata.org/wiki/Q2294884","display_name":"Derivatization","level":3,"score":0.7640317678451538},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.574767529964447},{"id":"https://openalex.org/C31827203","wikidata":"https://www.wikidata.org/wiki/Q874296","display_name":"Tandem mass spectrometry","level":3,"score":0.5427837371826172},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.5236018300056458},{"id":"https://openalex.org/C40684141","wikidata":"https://www.wikidata.org/wiki/Q902061","display_name":"Electrospray ionization","level":3,"score":0.509299635887146},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.4970538914203644},{"id":"https://openalex.org/C2778576202","wikidata":"https://www.wikidata.org/wiki/Q2540164","display_name":"Sample preparation","level":2,"score":0.46206697821617126},{"id":"https://openalex.org/C171679685","wikidata":"https://www.wikidata.org/wiki/Q3707695","display_name":"Isotope dilution","level":3,"score":0.45246315002441406},{"id":"https://openalex.org/C2778081958","wikidata":"https://www.wikidata.org/wiki/Q14906786","display_name":"Eosinophil peroxidase","level":4,"score":0.4371478259563446},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.30829739570617676},{"id":"https://openalex.org/C162008176","wikidata":"https://www.wikidata.org/wiki/Q419305","display_name":"Peroxidase","level":3,"score":0.28580141067504883},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09840169548988342}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:engagedscholarship.csuohio.edu:etdarchive-1276","doi":null,"is_oa":true,"landing_page_url":"https://engagedscholarship.csuohio.edu/etdarchive/277","pdf_url":"https://engagedscholarship.csuohio.edu/cgi/viewcontent.cgi?article=1276&context=etdarchive","source":{"id":"https://openalex.org/S4306400889","display_name":"EngagedScholarship @ Cleveland State University (Cleveland State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102607778","host_organization_name":"Cleveland State University","host_organization_lineage":["https://openalex.org/I102607778"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ETD Archive","raw_type":"text"},{"id":"pmh:oai:etd.ohiolink.edu:csu1226685494","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=csu1226685494","pdf_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=csu1226685494&disposition=inline","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=csu1226685494","raw_type":"text"},{"id":"mag:25535467","doi":null,"is_oa":false,"landing_page_url":"https://europepmc.org/article/ETH/3746","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:engagedscholarship.csuohio.edu:etdarchive-1276","doi":null,"is_oa":true,"landing_page_url":"https://engagedscholarship.csuohio.edu/etdarchive/277","pdf_url":"https://engagedscholarship.csuohio.edu/cgi/viewcontent.cgi?article=1276&context=etdarchive","source":{"id":"https://openalex.org/S4306400889","display_name":"EngagedScholarship @ Cleveland State University (Cleveland State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102607778","host_organization_name":"Cleveland State University","host_organization_lineage":["https://openalex.org/I102607778"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ETD Archive","raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309105","display_name":"Cleveland State University","ror":"https://ror.org/002tx1f22"},{"id":"https://openalex.org/F4320309680","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83"},{"id":"https://openalex.org/F4320309681","display_name":"Cleveland Clinic Foundation","ror":"https://ror.org/03xjacd83"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W25535467.pdf","grobid_xml":"https://content.openalex.org/works/W25535467.grobid-xml"},"referenced_works_count":249,"referenced_works":["https://openalex.org/W59175948","https://openalex.org/W71381248","https://openalex.org/W71627213","https://openalex.org/W111387551","https://openalex.org/W113714250","https://openalex.org/W120801443","https://openalex.org/W249641072","https://openalex.org/W936023199","https://openalex.org/W1007804022","https://openalex.org/W1009594272","https://openalex.org/W1044365214","https://openalex.org/W1483091000","https://openalex.org/W1484736436","https://openalex.org/W1485388451","https://openalex.org/W1487363849","https://openalex.org/W1491148615","https://openalex.org/W1496147757","https://openalex.org/W1517408457","https://openalex.org/W1522890520","https://openalex.org/W1525146040","https://openalex.org/W1537586088","https://openalex.org/W1549893833","https://openalex.org/W1559113856","https://openalex.org/W1566489422","https://openalex.org/W1567781128","https://openalex.org/W1572269513","https://openalex.org/W1576835394","https://openalex.org/W1587532579","https://openalex.org/W1595737442","https://openalex.org/W1599279594","https://openalex.org/W1600728530","https://openalex.org/W1637003823","https://openalex.org/W1662308449","https://openalex.org/W1672750600","https://openalex.org/W1680535784","https://openalex.org/W1731451328","https://openalex.org/W1759706356","https://openalex.org/W1796098629","https://openalex.org/W1797234058","https://openalex.org/W1801632833","https://openalex.org/W1821918060","https://openalex.org/W1830134817","https://openalex.org/W1868062960","https://openalex.org/W1883234535","https://openalex.org/W1898564295","https://openalex.org/W1914317054","https://openalex.org/W1942321004","https://openalex.org/W1943694240","https://openalex.org/W1955167637","https://openalex.org/W1963856249","https://openalex.org/W1964050294","https://openalex.org/W1964061049","https://openalex.org/W1966664051","https://openalex.org/W1971527431","https://openalex.org/W1971604243","https://openalex.org/W1974184540","https://openalex.org/W1975468510","https://openalex.org/W1975621743","https://openalex.org/W1976135055","https://openalex.org/W1977250424","https://openalex.org/W1977658165","https://openalex.org/W1978038466","https://openalex.org/W1978836958","https://openalex.org/W1980669672","https://openalex.org/W1981006181","https://openalex.org/W1981018813","https://openalex.org/W1981992662","https://openalex.org/W1982054375","https://openalex.org/W1983039463","https://openalex.org/W1984215166","https://openalex.org/W1984775161","https://openalex.org/W1985746519","https://openalex.org/W1986386412","https://openalex.org/W1986617626","https://openalex.org/W1987461579","https://openalex.org/W1987749678","https://openalex.org/W1987806264","https://openalex.org/W1988172837","https://openalex.org/W1988558765","https://openalex.org/W1988717330","https://openalex.org/W1989409713","https://openalex.org/W1989647300","https://openalex.org/W1990390910","https://openalex.org/W1990874728","https://openalex.org/W1992954095","https://openalex.org/W1997415154","https://openalex.org/W1998662190","https://openalex.org/W1999649376","https://openalex.org/W1999870502","https://openalex.org/W2001453406","https://openalex.org/W2006228166","https://openalex.org/W2008588972","https://openalex.org/W2009574758","https://openalex.org/W2010980890","https://openalex.org/W2011370051","https://openalex.org/W2013253952","https://openalex.org/W2013806166","https://openalex.org/W2013887838","https://openalex.org/W2014078838","https://openalex.org/W2016573311","https://openalex.org/W2016770221","https://openalex.org/W2017334823","https://openalex.org/W2017662760","https://openalex.org/W2018684370","https://openalex.org/W2018992923","https://openalex.org/W2019249650","https://openalex.org/W2019864861","https://openalex.org/W2021509182","https://openalex.org/W2022301096","https://openalex.org/W2024759299","https://openalex.org/W2024916351","https://openalex.org/W2025295834","https://openalex.org/W2025958871","https://openalex.org/W2027156358","https://openalex.org/W2027234736","https://openalex.org/W2031085331","https://openalex.org/W2031499823","https://openalex.org/W2031593366","https://openalex.org/W2032092394","https://openalex.org/W2033334870","https://openalex.org/W2033764116","https://openalex.org/W2034182255","https://openalex.org/W2035568334","https://openalex.org/W2035961359","https://openalex.org/W2035993583","https://openalex.org/W2036380708","https://openalex.org/W2037663265","https://openalex.org/W2038273933","https://openalex.org/W2038481368","https://openalex.org/W2039562073","https://openalex.org/W2040056874","https://openalex.org/W2040381576","https://openalex.org/W2040983125","https://openalex.org/W2041309279","https://openalex.org/W2042713021","https://openalex.org/W2043004415","https://openalex.org/W2043446682","https://openalex.org/W2044561878","https://openalex.org/W2045444107","https://openalex.org/W2045502875","https://openalex.org/W2046253710","https://openalex.org/W2046678280","https://openalex.org/W2046991199","https://openalex.org/W2047777256","https://openalex.org/W2048966030","https://openalex.org/W2049527513","https://openalex.org/W2051672316","https://openalex.org/W2051705991","https://openalex.org/W2052183375","https://openalex.org/W2053265457","https://openalex.org/W2053498385","https://openalex.org/W2053686180","https://openalex.org/W2053933829","https://openalex.org/W2057312068","https://openalex.org/W2057622151","https://openalex.org/W2058137293","https://openalex.org/W2058357010","https://openalex.org/W2058441068","https://openalex.org/W2058774619","https://openalex.org/W2060292403","https://openalex.org/W2060383651","https://openalex.org/W2060911392","https://openalex.org/W2062936268","https://openalex.org/W2067214540","https://openalex.org/W2069377997","https://openalex.org/W2069587720","https://openalex.org/W2070493096","https://openalex.org/W2070548987","https://openalex.org/W2070690965","https://openalex.org/W2071170294","https://openalex.org/W2071772324","https://openalex.org/W2073067623","https://openalex.org/W2074074558","https://openalex.org/W2074840334","https://openalex.org/W2075034126","https://openalex.org/W2075240566","https://openalex.org/W2077224253","https://openalex.org/W2079006586","https://openalex.org/W2080290873","https://openalex.org/W2080861797","https://openalex.org/W2082686558","https://openalex.org/W2083048897","https://openalex.org/W2084722577","https://openalex.org/W2085917914","https://openalex.org/W2086802420","https://openalex.org/W2086939860","https://openalex.org/W2087456280","https://openalex.org/W2087593387","https://openalex.org/W2088851495","https://openalex.org/W2088966168","https://openalex.org/W2091681038","https://openalex.org/W2092522316","https://openalex.org/W2094921988","https://openalex.org/W2095070102","https://openalex.org/W2095556498","https://openalex.org/W2096330954","https://openalex.org/W2096822956","https://openalex.org/W2097489620","https://openalex.org/W2100330873","https://openalex.org/W2104194752","https://openalex.org/W2104969714","https://openalex.org/W2104970183","https://openalex.org/W2107117207","https://openalex.org/W2107721620","https://openalex.org/W2107888488","https://openalex.org/W2108282128","https://openalex.org/W2113478642","https://openalex.org/W2114518763","https://openalex.org/W2115561143","https://openalex.org/W2116835524","https://openalex.org/W2117324772","https://openalex.org/W2117383170","https://openalex.org/W2119825850","https://openalex.org/W2120820350","https://openalex.org/W2121811672","https://openalex.org/W2124200344","https://openalex.org/W2124450625","https://openalex.org/W2126408606","https://openalex.org/W2128962388","https://openalex.org/W2131285272","https://openalex.org/W2134551277","https://openalex.org/W2138382873","https://openalex.org/W2140995900","https://openalex.org/W2144749256","https://openalex.org/W2146141276","https://openalex.org/W2148168402","https://openalex.org/W2148808954","https://openalex.org/W2150611725","https://openalex.org/W2158069865","https://openalex.org/W2162248888","https://openalex.org/W2162986958","https://openalex.org/W2168541174","https://openalex.org/W2168897708","https://openalex.org/W2179092050","https://openalex.org/W2181394789","https://openalex.org/W2187357944","https://openalex.org/W2214291492","https://openalex.org/W2291786253","https://openalex.org/W2312870247","https://openalex.org/W2316918019","https://openalex.org/W2327302142","https://openalex.org/W2339913251","https://openalex.org/W2396280090","https://openalex.org/W2399835641","https://openalex.org/W2408828438","https://openalex.org/W2416226571","https://openalex.org/W2419262985","https://openalex.org/W2421330260","https://openalex.org/W4232838206"],"related_works":["https://openalex.org/W1501408384","https://openalex.org/W1972907891","https://openalex.org/W7058275138","https://openalex.org/W3030031092","https://openalex.org/W2083475407","https://openalex.org/W2322333893","https://openalex.org/W2333871910","https://openalex.org/W6963943971","https://openalex.org/W2952786326","https://openalex.org/W2132553988"],"abstract_inverted_index":{"Eosinophil":[0],"peroxidase":[1],"(EPO)":[2],"and":[3,13,22,53,83,105,115,174,195,230],"myeloperoxidase":[4],"(MPO)":[5],"have":[6,75],"been":[7,28,77],"implicated":[8],"in":[9,17,63,97,132,214,256],"generating":[10,129],"reactive":[11,38],"species":[12],"promoting":[14],"oxidative":[15,48],"modifications":[16],"numerous":[18],"diseases.":[19],"The":[20],"detection":[21,87,156],"identification":[23],"of":[24,36,47,86,140,148,157,161,210,223,227,237],"potential":[25,88],"pathways":[26],"has":[27],"proven":[29],"extremely":[30],"challenge":[31,118],"due":[32],"to":[33,43,51,232],"evanescence":[34],"nature":[35],"these":[37],"species.":[39],"An":[40],"alternative":[41],"approach":[42],"study":[44],"the":[45,55,84,125,135,143,155],"involvement":[46],"modification":[49],"is":[50,124],"detect":[52],"quantify":[54],"stable":[56,100],"molecular":[57],"fingerprints,":[58],"like":[59],"oxidized":[60,72,167,254],"tyrosine":[61,168,255],"species,":[62],"biological":[64],"matrices.":[65],"Previously":[66],"reported":[67],"analytical":[68],"methods":[69],"for":[70,128,137,165],"quantifying":[71],"amino":[73,207],"acids":[74],"typically":[76],"limited":[78],"by:":[79],"low":[80],"sensitivity,":[81],"specificity":[82],"failure":[85],"oxidation":[89,149,201],"products":[90,150,202],"generated":[91],"during":[92],"sample":[93,170],"handling.":[94],"Using":[95,111,241],"GC/MS":[96,114],"combination":[98],"with":[99,154,183,204,217],"isotope":[101],"dilution,":[102],"a":[103,180],"sensitive":[104],"self-quality":[106],"control":[107],"assay":[108,191],"was":[109],"developed.":[110],"this":[112,242],"isotope-dilution":[113],"multiple":[116,197],"allergen":[117],"models,":[119],"we":[120,178,248],"demonstrate":[121],"that":[122,145,192],"EPO":[123],"major":[126],"pathway":[127],"protein-bound":[130],"3-bromotyrosine":[131],"vivo.":[133],"However,":[134],"need":[136],"chemical":[138,264],"derivatization":[139,163],"samples":[141],"increases":[142],"possibility":[144],"artifactual":[146],"generation":[147],"which":[151],"may":[152],"interfere":[153],"native":[158],"levels.":[159],"Requirement":[160],"unique":[162],"reagent":[164],"each":[166],"results":[169],"analysis":[171],"both":[172],"cumbersome":[173],"time/labor":[175],"intensive.":[176],"Therefore,":[177],"develop":[179],"liquid":[181],"chromatography":[182],"on-line":[184,221],"electrospray":[185],"ionization":[186],"tandem":[187],"mass":[188,238],"spectrometry":[189],"(LC-ESI/MS/MS)":[190],"simultaneously":[193],"detects":[194],"quantifies":[196],"structurally":[198],"informative":[199],"protein":[200],"along":[203],"their":[205],"precursor":[206],"acids.":[208],"Use":[209],"four":[211],"HPLC":[212],"systems":[213],"multiplex":[215],"array":[216],"column":[218],"switching":[219],"permits":[220],"analyses":[222],"only":[224],"relevant":[225],"portions":[226],"chromatographic":[228],"profiles":[229],"up":[231],"four-fold":[233],"increased":[234],"throughput":[235],"efficiency":[236],"detector":[239],"usage.":[240],"high-throughput":[243],"multiplexed":[244],"array-based":[245],"LC-MS/MS":[246],"method,":[247],"found":[249],"significant":[250],"correlations":[251,262],"among":[252],"individual":[253],"sera":[257],"from":[258],"healthy":[259],"volunteers.":[260],"These":[261],"provide":[263]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}