{"id":"https://openalex.org/W2551860960","doi":null,"title":"Synaptic Noise-like Activity in Hippocampal Interneurons","display_name":"Synaptic Noise-like Activity in Hippocampal Interneurons","publication_year":2010,"publication_date":"2010-02-15","ids":{"openalex":"https://openalex.org/W2551860960","mag":"2551860960"},"language":"en","primary_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/18882","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/18882","pdf_url":"https://utoronto.scholaris.ca/bitstreams/4444f1ae-df88-4ac6-a2ad-a1046eae1011/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://utoronto.scholaris.ca/bitstreams/4444f1ae-df88-4ac6-a2ad-a1046eae1011/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071161326","display_name":"David A. Stanley","orcid":"https://orcid.org/0000-0001-9220-7292","observed_orcids":["https://orcid.org/0000-0001-9220-7292"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"David A. Stanley","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9220-7292","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5071161326"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.6693999767303467,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.6693999767303467,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.20579999685287476,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0989999994635582,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hippocampal-interneurons","display_name":"hippocampal interneurons","score":0.9449999928474426},{"id":"https://openalex.org/keywords/power-law-scaling","display_name":"power-law scaling","score":0.7609999775886536},{"id":"https://openalex.org/keywords/power-spectral-density","display_name":"power spectral density","score":0.9869999885559082},{"id":"https://openalex.org/keywords/biophysical-neuron-models","display_name":"biophysical neuron models","score":0.609000027179718}],"concepts":[{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6961711645126343},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6909650564193726},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32767754793167114},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3261423110961914}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:utoronto.scholaris.ca:1807/18882","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/18882","pdf_url":"https://utoronto.scholaris.ca/bitstreams/4444f1ae-df88-4ac6-a2ad-a1046eae1011/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:collectionscanada.gc.ca:OTU.1807/18882","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1807/18882","pdf_url":null,"source":{"id":"https://openalex.org/S4306402307","display_name":"Library and Archives Canada (Government of Canada)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2802286613","host_organization_name":"Government of Canada","host_organization_lineage":["https://openalex.org/I2802286613"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2551860960","doi":null,"is_oa":false,"landing_page_url":"https://tspace.library.utoronto.ca/bitstream/1807/18882/1/Stanley_David_A_200911_MASc_thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/18882","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/18882","pdf_url":"https://utoronto.scholaris.ca/bitstreams/4444f1ae-df88-4ac6-a2ad-a1046eae1011/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2551860960.pdf","grobid_xml":"https://content.openalex.org/works/W2551860960.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W1520220741","https://openalex.org/W1735445987","https://openalex.org/W1808320809","https://openalex.org/W1825044724","https://openalex.org/W1852401591","https://openalex.org/W1921693572","https://openalex.org/W1928151192","https://openalex.org/W1942615418","https://openalex.org/W1968687601","https://openalex.org/W1983704513","https://openalex.org/W1985940938","https://openalex.org/W2019484205","https://openalex.org/W2020563598","https://openalex.org/W2029401646","https://openalex.org/W2033905848","https://openalex.org/W2039128802","https://openalex.org/W2054224256","https://openalex.org/W2057833549","https://openalex.org/W2071007053","https://openalex.org/W2074138173","https://openalex.org/W2088155512","https://openalex.org/W2099654960","https://openalex.org/W2105935234","https://openalex.org/W2123553271","https://openalex.org/W2131215403","https://openalex.org/W2133301037","https://openalex.org/W2139852988","https://openalex.org/W2143663381","https://openalex.org/W2147435778","https://openalex.org/W2148126095","https://openalex.org/W2152896566","https://openalex.org/W2154323800","https://openalex.org/W2584256140"],"related_works":["https://openalex.org/W2045218680","https://openalex.org/W2137020833","https://openalex.org/W2048126627","https://openalex.org/W4245754230","https://openalex.org/W2115048871","https://openalex.org/W2031650785","https://openalex.org/W7096110392","https://openalex.org/W2994307059","https://openalex.org/W2015262011","https://openalex.org/W2115581795"],"abstract_inverted_index":{"Noise-like":[0],"activity":[1],"(NLA)":[2],"refers":[3],"to":[4,25,33,57,104,132],"spontaneous":[5],"subthreshold":[6,120],"fluctuations":[7,21,87,112],"in":[8,23,52,75,119],"membrane":[9],"potential.":[10],"In":[11],"this":[12],"thesis,":[13],"we":[14,48,92],"examine":[15],"the":[16,42,50,53,65,76,101,129],"role":[17,118],"that":[18,94,109],"synaptic":[19,45,85,102,110,124,130],"channel":[20,46,86,111],"play":[22,115],"contributing":[24],"NLA":[26,125],"by":[27,128],"comparing":[28],"a":[29,89,116],"detailed":[30],"biophysical":[31],"model":[32,54],"experimental":[34],"data":[35],"from":[36,44,55],"whole-intact":[37],"hippocampal":[38],"interneurons.":[39],"To":[40],"represent":[41],"contribution":[43],"fluctuations,":[47],"switch":[49],"synapses":[51],"traditional":[56],"Markovian":[58],"formalisms":[59],"and":[60,71,79],"demonstrate":[61],"statistically":[62],"relevant":[63],"increases":[64],"standard":[66],"deviation;":[67],"power-law":[68],"scaling":[69],"exponent;":[70],"power":[72],"spectral":[73],"density":[74],"5-100":[77],"Hz":[78],"1-5":[80],"kHz":[81],"ranges.":[82],"However,":[83],"while":[84],"have":[88],"definite":[90],"effect,":[91],"found":[93],"they":[95],"were":[96],"significantly":[97],"more":[98],"subtle":[99],"than":[100],"response":[103,131],"network":[105,134],"activity.":[106,135],"This":[107],"indicates":[108],"do":[113],"indeed":[114],"significant":[117],"noise,":[121],"but,":[122],"overall,":[123],"is":[126],"dominated":[127],"presynaptic":[133]},"counts_by_year":[],"updated_date":"2026-09-09T07:26:56.047234","created_date":"2016-11-30T00:00:00"}