{"id":"https://openalex.org/W2551589972","doi":null,"title":"Glucocorticoid Receptor Function and its Role in Tamoxifen Resistance","display_name":"Glucocorticoid Receptor Function and its Role in Tamoxifen Resistance","publication_year":2015,"publication_date":"2015-09-26","ids":{"openalex":"https://openalex.org/W2551589972","mag":"2551589972"},"language":"en","primary_location":{"id":"pmh:oai:queensu.scholaris.ca:1974/13692","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1974/13692","pdf_url":null,"source":{"id":"https://openalex.org/S4306402568","display_name":"QSpace (Queen's University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204722609","host_organization_name":"Queen's University","host_organization_lineage":["https://openalex.org/I204722609"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061303686","display_name":"Erin Sellars","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Erin Sellars","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5061303686"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glucocorticoid-receptor","display_name":"glucocorticoid receptor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tamoxifen-resistance","display_name":"tamoxifen resistance","score":0.9959999918937683},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7139999866485596},{"id":"https://openalex.org/keywords/endocrine-therapy","display_name":"endocrine therapy","score":0.6000000238418579},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.5120000243186951}],"concepts":[{"id":"https://openalex.org/C59493245","wikidata":"https://www.wikidata.org/wiki/Q14877410","display_name":"Glucocorticoid receptor","level":3,"score":0.740979790687561},{"id":"https://openalex.org/C2777176818","wikidata":"https://www.wikidata.org/wiki/Q412178","display_name":"Tamoxifen","level":4,"score":0.6496517658233643},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6281290054321289},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.5961941480636597},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.5170100927352905},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5120180249214172},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.4966917634010315},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.4455804228782654},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.43940457701683044},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42777299880981445},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4105416536331177},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3919615149497986},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.38013899326324463},{"id":"https://openalex.org/C2780841215","wikidata":"https://www.wikidata.org/wiki/Q422549","display_name":"Glucocorticoid","level":2,"score":0.3764476180076599},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35362350940704346},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3534325957298279},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34936559200286865},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34694719314575195},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3251381516456604},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.18136385083198547},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08804884552955627},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06743410229682922}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:queensu.scholaris.ca:1974/13692","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1974/13692","pdf_url":null,"source":{"id":"https://openalex.org/S4306402568","display_name":"QSpace (Queen's University Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204722609","host_organization_name":"Queen's University","host_organization_lineage":["https://openalex.org/I204722609"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"mag:2551589972","doi":null,"is_oa":false,"landing_page_url":"https://qspace.library.queensu.ca/bitstream/1974/13692/1/Sellars_Erin_L_201509_MSc.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.4043000042438507,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":170,"referenced_works":["https://openalex.org/W141123821","https://openalex.org/W311989460","https://openalex.org/W656787866","https://openalex.org/W1490750970","https://openalex.org/W1515001041","https://openalex.org/W1517183311","https://openalex.org/W1529944274","https://openalex.org/W1542090274","https://openalex.org/W1548644314","https://openalex.org/W1562190372","https://openalex.org/W1593081305","https://openalex.org/W1594205240","https://openalex.org/W1602614022","https://openalex.org/W1611445504","https://openalex.org/W1684164190","https://openalex.org/W1752892371","https://openalex.org/W1825468856","https://openalex.org/W1835200336","https://openalex.org/W1892136299","https://openalex.org/W1896854564","https://openalex.org/W1965084309","https://openalex.org/W1967186439","https://openalex.org/W1970732873","https://openalex.org/W1971323804","https://openalex.org/W1971679151","https://openalex.org/W1971861967","https://openalex.org/W1975426519","https://openalex.org/W1978125302","https://openalex.org/W1979067350","https://openalex.org/W1979181245","https://openalex.org/W1979419333","https://openalex.org/W1980039397","https://openalex.org/W1981330492","https://openalex.org/W1982535740","https://openalex.org/W1984484474","https://openalex.org/W1987791430","https://openalex.org/W1990047266","https://openalex.org/W1990582579","https://openalex.org/W1995106518","https://openalex.org/W1995257163","https://openalex.org/W1995462644","https://openalex.org/W1998351354","https://openalex.org/W2000297826","https://openalex.org/W2000437208","https://openalex.org/W2002262418","https://openalex.org/W2002302708","https://openalex.org/W2003523045","https://openalex.org/W2003911872","https://openalex.org/W2003936181","https://openalex.org/W2004502371","https://openalex.org/W2008390304","https://openalex.org/W2008654807","https://openalex.org/W2011866590","https://openalex.org/W2012670645","https://openalex.org/W2013640714","https://openalex.org/W2013956549","https://openalex.org/W2015766045","https://openalex.org/W2017036633","https://openalex.org/W2017319763","https://openalex.org/W2017830116","https://openalex.org/W2019002206","https://openalex.org/W2019774245","https://openalex.org/W2021828774","https://openalex.org/W2022671765","https://openalex.org/W2028122342","https://openalex.org/W2029821696","https://openalex.org/W2032298890","https://openalex.org/W2033417844","https://openalex.org/W2033940616","https://openalex.org/W2034830752","https://openalex.org/W2035034589","https://openalex.org/W2036148005","https://openalex.org/W2036681504","https://openalex.org/W2037539635","https://openalex.org/W2038631211","https://openalex.org/W2039124133","https://openalex.org/W2040532631","https://openalex.org/W2042622775","https://openalex.org/W2043382313","https://openalex.org/W2045008807","https://openalex.org/W2045058193","https://openalex.org/W2045349814","https://openalex.org/W2045563337","https://openalex.org/W2047863929","https://openalex.org/W2048655147","https://openalex.org/W2049761405","https://openalex.org/W2052024663","https://openalex.org/W2054164997","https://openalex.org/W2054211750","https://openalex.org/W2056242601","https://openalex.org/W2057706543","https://openalex.org/W2059210970","https://openalex.org/W2063478423","https://openalex.org/W2064469818","https://openalex.org/W2065373256","https://openalex.org/W2067048774","https://openalex.org/W2070061120","https://openalex.org/W2075663330","https://openalex.org/W2076446882","https://openalex.org/W2076875002","https://openalex.org/W2078084967","https://openalex.org/W2079533675","https://openalex.org/W2079808933","https://openalex.org/W2080961843","https://openalex.org/W2081673578","https://openalex.org/W2082331771","https://openalex.org/W2084400739","https://openalex.org/W2086117273","https://openalex.org/W2088210377","https://openalex.org/W2092123619","https://openalex.org/W2092900546","https://openalex.org/W2092967525","https://openalex.org/W2093646356","https://openalex.org/W2093676604","https://openalex.org/W2094187675","https://openalex.org/W2095697356","https://openalex.org/W2097682151","https://openalex.org/W2098039383","https://openalex.org/W2099257018","https://openalex.org/W2099789976","https://openalex.org/W2100149411","https://openalex.org/W2101082219","https://openalex.org/W2103188824","https://openalex.org/W2104773672","https://openalex.org/W2105930632","https://openalex.org/W2106663556","https://openalex.org/W2106891649","https://openalex.org/W2108219444","https://openalex.org/W2109388713","https://openalex.org/W2112907191","https://openalex.org/W2114557980","https://openalex.org/W2114586605","https://openalex.org/W2115443739","https://openalex.org/W2123944872","https://openalex.org/W2123999563","https://openalex.org/W2125747634","https://openalex.org/W2126422047","https://openalex.org/W2126848032","https://openalex.org/W2127573529","https://openalex.org/W2128003724","https://openalex.org/W2129773815","https://openalex.org/W2130478351","https://openalex.org/W2130818619","https://openalex.org/W2134393064","https://openalex.org/W2141647078","https://openalex.org/W2145193688","https://openalex.org/W2146384083","https://openalex.org/W2146604249","https://openalex.org/W2152584857","https://openalex.org/W2153466861","https://openalex.org/W2154302022","https://openalex.org/W2154313625","https://openalex.org/W2156120082","https://openalex.org/W2156933633","https://openalex.org/W2158422264","https://openalex.org/W2158997529","https://openalex.org/W2159427817","https://openalex.org/W2161991320","https://openalex.org/W2168011358","https://openalex.org/W2169642801","https://openalex.org/W2171238991","https://openalex.org/W2171852634","https://openalex.org/W2227238913","https://openalex.org/W2292249227","https://openalex.org/W2318605753","https://openalex.org/W2325149713","https://openalex.org/W2466461729","https://openalex.org/W2489128652","https://openalex.org/W2567460580","https://openalex.org/W2604614135"],"related_works":["https://openalex.org/W7216710640","https://openalex.org/W2588421031","https://openalex.org/W2895855223","https://openalex.org/W7217762168","https://openalex.org/W2047806048","https://openalex.org/W2555677842","https://openalex.org/W2396510339","https://openalex.org/W2023686860","https://openalex.org/W6979066973","https://openalex.org/W2095523253"],"abstract_inverted_index":{"Thesis":[0],"(Master,":[1],"Biochemistry)":[2],"--":[3],"Queen's":[4],"University,":[5],"2015-09-26":[6],"15:49:19.108":[7]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-11-30T00:00:00"}