{"id":"https://openalex.org/W2551488339","doi":"https://doi.org/10.1182/blood.v114.22.2222.2222","title":"Early Immune Recovery Predicts Overall and Disease-Free Survival After Allogeneic Hematopoietic Stem Cell Transplantation.","display_name":"Early Immune Recovery Predicts Overall and Disease-Free Survival After Allogeneic Hematopoietic Stem Cell Transplantation.","publication_year":2009,"publication_date":"2009-11-20","ids":{"openalex":"https://openalex.org/W2551488339","doi":"https://doi.org/10.1182/blood.v114.22.2222.2222","mag":"2551488339"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v114.22.2222.2222","doi":"https://doi.org/10.1182/blood.v114.22.2222.2222","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v114.22.2222.2222","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5106236071","display_name":"Jenna D. Goldberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jenna D. Goldberg","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048552055","display_name":"Junting Zheng","orcid":"https://orcid.org/0000-0002-2946-8403","observed_orcids":["https://orcid.org/0000-0002-2946-8403"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junting Zheng","raw_affiliation_strings":["Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071626276","display_name":"Juliet N. Barker","orcid":"https://orcid.org/0000-0002-9030-183X","observed_orcids":["https://orcid.org/0000-0002-9030-183X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juliet Barker","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067712388","display_name":"Farid Boulad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Farid Boulad","raw_affiliation_strings":["Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043966208","display_name":"Hugo R Castro-Malaspina","orcid":"https://orcid.org/0000-0002-9956-904X","observed_orcids":["https://orcid.org/0000-0002-9956-904X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H.R. Castro-Malaspina","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056539557","display_name":"Katharine C. Hsu","orcid":"https://orcid.org/0000-0003-2827-5324","observed_orcids":["https://orcid.org/0000-0003-2827-5324"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Katharine C Hsu","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031349996","display_name":"Ann Alice Jakubowski","orcid":"https://orcid.org/0000-0003-1955-513X","observed_orcids":["https://orcid.org/0000-0003-1955-513X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ann Jakubowski","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079103223","display_name":"Nancy A. Kernan","orcid":"https://orcid.org/0000-0003-1417-1823","observed_orcids":["https://orcid.org/0000-0003-1417-1823"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nancy Kernan","raw_affiliation_strings":["Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108531125","display_name":"Richard J. O\u2019Reilly","orcid":"https://orcid.org/0000-0002-8997-5490","observed_orcids":["https://orcid.org/0000-0002-8997-5490"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard J O'Reilly,","raw_affiliation_strings":["Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058746837","display_name":"Esperanza Bouza Papadopoulos","orcid":"https://orcid.org/0000-0001-6066-1861","observed_orcids":["https://orcid.org/0000-0001-6066-1861"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Esperanza Papadopoulos","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052956899","display_name":"Susan E. Prockop","orcid":"https://orcid.org/0000-0003-4175-5728","observed_orcids":["https://orcid.org/0000-0003-4175-5728"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Prockop","raw_affiliation_strings":["Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085595407","display_name":"Andromachi Scaradavou","orcid":"https://orcid.org/0000-0003-2425-1069","observed_orcids":["https://orcid.org/0000-0003-2425-1069"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andromachi Scaradavou","raw_affiliation_strings":["Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003503263","display_name":"Marcel R.M. van den Brink","orcid":"https://orcid.org/0000-0003-0696-4401","observed_orcids":["https://orcid.org/0000-0003-0696-4401"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marcel van den Brink","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036520753","display_name":"James W. Young","orcid":"https://orcid.org/0000-0002-0032-6559","observed_orcids":["https://orcid.org/0000-0002-0032-6559"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"James Young","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031035765","display_name":"Glenn Heller","orcid":"https://orcid.org/0000-0001-9217-8348","observed_orcids":["https://orcid.org/0000-0001-9217-8348"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Glenn Heller","raw_affiliation_strings":["Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082333371","display_name":"Miguel\u2010Angel Perales","orcid":"https://orcid.org/0000-0002-5910-4571","observed_orcids":["https://orcid.org/0000-0002-5910-4571"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miguel-Angel Perales","raw_affiliation_strings":["Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Allogeneic Bone Marrow Transplantation, Memorial Sloan-Kettering Cancer Center, New York, NY, USA,","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003503263","https://openalex.org/A5031035765","https://openalex.org/A5031349996","https://openalex.org/A5036520753","https://openalex.org/A5056539557","https://openalex.org/A5058746837","https://openalex.org/A5067712388","https://openalex.org/A5079103223"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.38973256,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"114","issue":"22","first_page":"2222","last_page":"2222"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allogeneic-hematopoietic-stem-cell-transplantation","display_name":"allogeneic hematopoietic stem cell transplantation","score":0.9490000009536743},{"id":"https://openalex.org/keywords/immune-recovery","display_name":"immune recovery","score":0.7519999742507935},{"id":"https://openalex.org/keywords/absolute-lymphocyte-count","display_name":"absolute lymphocyte count","score":0.8399999737739563},{"id":"https://openalex.org/keywords/cd4-t-cell-reconstitution","display_name":"CD4+ T cell recovery","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9200000166893005},{"id":"https://openalex.org/keywords/lymphocyte-subsets","display_name":"lymphocyte subsets","score":0.8029999732971191},{"id":"https://openalex.org/keywords/t-cell-depletion","display_name":"T cell depletion","score":0.6570000052452087},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.7789999842643738},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7839999794960022},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.6449999809265137},{"id":"https://openalex.org/keywords/leukemia","display_name":"leukemia","score":0.5389999747276306},{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":0.7450000047683716},{"id":"https://openalex.org/keywords/non-hodgkin-lymphoma","display_name":"non-Hodgkin lymphoma","score":0.8999999761581421}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6621724963188171},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.6560467481613159},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6025725603103638},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5267231464385986},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.4927575886249542},{"id":"https://openalex.org/C2779695342","wikidata":"https://www.wikidata.org/wiki/Q5296800","display_name":"Donor lymphocyte infusion","level":4,"score":0.48932287096977234},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4694518446922302},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4607575535774231},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.43342143297195435},{"id":"https://openalex.org/C141341695","wikidata":"https://www.wikidata.org/wiki/Q2368661","display_name":"Surrogate endpoint","level":2,"score":0.4202287197113037},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4201824963092804},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16723567247390747},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1182/blood.v114.22.2222.2222","doi":"https://doi.org/10.1182/blood.v114.22.2222.2222","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v114.22.2222.2222","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4401106519","https://openalex.org/W2578541515","https://openalex.org/W2115040239","https://openalex.org/W2894971993","https://openalex.org/W4284709448","https://openalex.org/W2010769370","https://openalex.org/W4231732759","https://openalex.org/W2802203992","https://openalex.org/W3029361554","https://openalex.org/W2560402060"],"abstract_inverted_index":{"Abstract":[0,1],"2222":[2],"Poster":[3],"Board":[4],"II-199":[5],"Background:":[6],"Immune":[7,190],"recovery":[8,28,60,82,99,191],"is":[9,575,612,621],"an":[10,108,155],"important":[11,109,554],"determinant":[12],"of":[13,29,51,61,78,90,96,208,230,236,303,471,482,490,542,556,592,635],"outcome":[14],"after":[15,83,144,560],"allogeneic":[16],"hematopoietic":[17],"stem":[18,305],"cell":[19,81,306,380,474],"transplantation":[20],"(alloHSCT).":[21],"Previous":[22],"studies":[23,579],"have":[24,58,72,184],"demonstrated":[25,365],"that":[26,75,366,539,566,590,623],"early":[27,549],"absolute":[30],"lymphocyte":[31,97,199,322],"count":[32,381,408,421,448,475],"(ALC)":[33],"predicts":[34,569,600],"overall":[35],"(OS)":[36],"and":[37,44,53,102,137,172,198,216,239,243,288,308,338,390,398,411,424,435,451,461,498,558,583,602,617],"disease":[38],"free":[39],"survival":[40,104,259,484,601],"(DFS)":[41],"in":[42,261,294,500,571,580,604],"conventional":[43,52,582,630],"partially":[45,584],"T-cell":[46,407,420,447],"depleted":[47],"(TCD)":[48],"alloHSCT.":[49,563],"Recipients":[50],"especially":[54],"TCD":[55,84,130,562,573,585,606],"alloHSCT":[56,85,106,131,631],"can":[57],"prolonged":[59],"their":[62,276],"immune":[63,158,534,543,618,655],"systems,":[64],"which":[65,151],"may":[66,642],"extend":[67],"beyond":[68],"one":[69,202],"year.":[70],"We":[71,112,140,176,537,587],"previously":[73],"shown":[74],"the":[76,88,94,222,228,234,251,255,295,317,572,581,605,633],"rate":[77],"CD4+":[79,238,406,419,446,597],"T":[80,241,473,598],"correlates":[86],"with":[87,233,258,321,348,357,373,387,443,476,524,531,577],"risk":[89],"opportunistic":[91],"infections.":[92],"However,":[93],"impact":[95],"subset":[98],"on":[100,117,157],"relapse":[101,523,603],"long-term":[103],"following":[105],"remains":[107],"unknown.":[110],"Methods:":[111],"conducted":[113],"a":[114,128,272],"retrospective":[115],"study":[116],"353":[118],"consecutive":[119],"patients":[120,142,178,645],"(median":[121],"age":[122],"39,":[123],"range":[124],"2-68)":[125],"who":[126,179,513],"received":[127,148],"fully":[129,561],"at":[132,330,382,409,422,449],"MSKCC":[133],"between":[134,615],"January":[135],"1997":[136],"December":[138],"2005.":[139],"excluded":[141,177],"transplanted":[143],"2005,":[145],"because":[146],"they":[147],"KGF":[149],"for":[150,510],"pre-clinical":[152],"data":[153],"suggest":[154],"effect":[156],"recovery.":[159,323,535,619],"Diseases":[160],"included":[161,485],"ALL":[162],"(85),":[163],"AML":[164],"(146),":[165],"CML":[166,511],"(43),":[167],"MDS":[168],"(31),":[169],"NHL":[170],"(47),":[171],"undifferentiated":[173],"leukemia":[174],"(1).":[175],"died":[180],"or":[181,478],"did":[182,504],"not":[183,505,518,529],"stable":[185],"engraftment":[186],"by":[187,206,392],"30":[188,332,353,369,568,638],"days.":[189],"data,":[192],"including":[193,545],"ALC":[194,329,352,368,567,637],"through":[195,201],"day":[196,331,339,383,551],"90":[197],"subsets":[200],"year":[203],"were":[204,214,269,282,319,346],"grouped":[205],"quartile":[207],"cohort":[209],"(table).":[210],"The":[211,218,279,312],"primary":[212],"endpoints":[213,232],"OS":[215,375,389,428,456,477,557,570],"DFS.":[217,479],"score":[219,249],"statistic":[220],"from":[221,650],"Cox":[223,252,296],"proportional":[224],"hazards":[225],"model":[226,253,297],"defined":[227],"association":[229,470],"these":[231,624],"values":[235,256],"ALC,":[237],"CD8+":[240,472],"cells,":[242],"NK":[244,379,593],"cells.":[245],"Subsequent":[246],"to":[247,263,521,629,648,652],"individual":[248],"tests,":[250],"determined":[254],"associated":[257,320,347,356,372,386,530],"endpoints,":[260],"addition":[262],"prognostic":[264,277],"clinical":[265,507],"factors.":[266],"Because":[267],"markers":[268],"measured":[270],"post-HSCT,":[271],"landmark":[273,280],"analysis":[274,364],"explored":[275],"significance.":[278],"times":[281],"1,":[283],"2,":[284],"3,":[285],"6,":[286],"9,":[287],"12":[289,412,425,452],"months":[290,413,426,453],"post-HSCT.":[291],"Additional":[292],"factors":[293],"were:":[298],"patient":[299],"sex,":[300],"age,":[301,487],"number":[302],"remissions,":[304],"source,":[307,497],"donor-recipient":[309],"HLA":[310,491],"match.":[311],"Kruskal-Wallis":[313],"test":[314],"evaluated":[315],"if":[316],"diagnoses":[318],"Results:":[324],"In":[325],"univariate":[326,393,417],"analysis,":[327,418],"high":[328,367],"(ALC":[333,341],"30,":[334,552],"p":[335,343,432],"<":[336,433],"0.001)":[337,434],"60":[340,384],"60,":[342],"=":[344,361,377,395,401,430,458,464],"0.015)":[345],"improved":[349,358,374,388,483],"OS.":[350],"High":[351],"was":[354,370,385,468,528],"also":[355,627],"DFS":[359,391,436,462,516,559],"(p":[360,376,394,400,429,457,463],"0.005).":[362],"Multivariate":[363],"independently":[371,454],"0.011).":[378],"0.014,":[396],"0.010)":[397],"multivariate":[399,444],"0.007,":[402,431],"0.002)":[403],"analysis.":[404,445],"Similarly,":[405],"6":[410,423,450],"predicted":[414,427,455],"survival.":[415],"By":[416],"(p=":[437],"0.032,":[438],"0.002).":[439],"This":[440],"relationship":[441,614],"remained":[442],"0.013,":[459],"0.007)":[460],"0.059,":[465],"0.043).":[466],"There":[467],"no":[469,613],"Other":[480],"predictors":[481,555],"younger":[486],"higher":[488],"degree":[489],"match,":[492],"peripheral":[493],"blood":[494],"as":[495,548,550],"stem-cell":[496],"transplant":[499,533],"1st":[501],"remission.":[502],"Diagnosis":[503],"differentiate":[506],"outcomes":[508],"except":[509],"patients,":[512],"had":[514],"decreased":[515],"(but":[517],"OS)":[519],"secondary":[520],"increased":[522],"TCD.":[525],"Finally,":[526,608],"diagnosis":[527,616],"post":[532],"Discussion:":[536],"demonstrate":[538,589],"several":[540],"measures":[541],"recovery,":[544],"time":[546],"points":[547],"are":[553],"Our":[564],"finding":[565],"setting":[574],"consistent":[576],"prior":[578],"settings.":[586],"further":[588],"reconstitution":[591],"cells":[594,599],"and,":[595],"later,":[596],"setting.":[607],"we":[609],"show":[610],"there":[611],"It":[620],"likely":[622,647],"findings":[625],"will":[626],"apply":[628],"given":[632],"concordance":[634],"our":[636],"outcomes.":[639],"These":[640],"results":[641],"help":[643],"identify":[644],"most":[646],"benefit":[649],"interventions":[651],"enhance":[653],"post-alloHSCT":[654],"reconstitution.":[656],"Disclosures:":[657],"Castro-Malaspina:":[658],"Alexion:":[659],"Consultancy,":[660],"Honoraria.":[661]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-11-30T00:00:00"}