{"id":"https://openalex.org/W2551246501","doi":"https://doi.org/10.1007/s00404-016-4211-x","title":"A first-in-human, randomized, controlled, subject- and reviewer-blinded multicenter study of Actamax\u2122 Adhesion Barrier","display_name":"A first-in-human, randomized, controlled, subject- and reviewer-blinded multicenter study of Actamax\u2122 Adhesion Barrier","publication_year":2016,"publication_date":"2016-11-14","ids":{"openalex":"https://openalex.org/W2551246501","doi":"https://doi.org/10.1007/s00404-016-4211-x","mag":"2551246501","pmid":"https://pubmed.ncbi.nlm.nih.gov/27844212","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5281664"},"language":"en","primary_location":{"id":"doi:10.1007/s00404-016-4211-x","doi":"https://doi.org/10.1007/s00404-016-4211-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00404-016-4211-x","pdf_url":"https://link.springer.com/content/pdf/10.1007%2Fs00404-016-4211-x.pdf","source":{"id":"https://openalex.org/S568598","display_name":"Archives of Gynecology and Obstetrics","issn_l":"0003-9128","issn":["0003-9128","0170-9925","0932-0067","1432-0711"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Gynecology and Obstetrics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007%2Fs00404-016-4211-x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021353845","display_name":"Geoffrey H Trew","orcid":"https://orcid.org/0000-0001-8329-7513","observed_orcids":["https://orcid.org/0000-0001-8329-7513"]},"institutions":[{"id":"https://openalex.org/I2801748203","display_name":"Hammersmith Hospital","ror":"https://ror.org/05jg8yp15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2801748203"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Geoffrey H. Trew","raw_affiliation_strings":["Consultant in Reproductive Medicine and Surgery, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK. g.trew@imperial.ac.uk","Consultant in Reproductive Medicine and Surgery, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Consultant in Reproductive Medicine and Surgery, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK. g.trew@imperial.ac.uk","institution_ids":["https://openalex.org/I2801748203"]},{"raw_affiliation_string":"Consultant in Reproductive Medicine and Surgery, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK","institution_ids":["https://openalex.org/I2801748203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006018557","display_name":"George A. Pistofidis","orcid":"https://orcid.org/0000-0002-7640-0698","observed_orcids":["https://orcid.org/0000-0002-7640-0698"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George A. Pistofidis","raw_affiliation_strings":["Department of Gynecological Endoscopic Surgery, Lefkos Stavros Hospital, Athens, 115 28, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Endoscopic Surgery, Lefkos Stavros Hospital, Athens, 115 28, Greece","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023008141","display_name":"Sara Yvonne Brucker","orcid":"https://orcid.org/0000-0001-5162-1542","observed_orcids":["https://orcid.org/0000-0001-5162-1542","https://orcid.org/0000-0001-8588-1094"]},"institutions":[{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sara Y. Brucker","raw_affiliation_strings":["Department of Gynecology and Obstetrics, University of T\u00fcbingen, T\u00fcbingen, 72076, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Obstetrics, University of T\u00fcbingen, T\u00fcbingen, 72076, Germany","institution_ids":["https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bernhard Kr\u00e4mer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bernhard Kr\u00e4mer","raw_affiliation_strings":["Department of Gynecology and Obstetrics, University of T\u00fcbingen, T\u00fcbingen, 72076, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Obstetrics, University of T\u00fcbingen, T\u00fcbingen, 72076, Germany","institution_ids":["https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101848018","display_name":"Nicole Ziegler","orcid":"https://orcid.org/0000-0002-8327-8619","observed_orcids":["https://orcid.org/0000-0002-8327-8619"]},"institutions":[{"id":"https://openalex.org/I4210125974","display_name":"Pius Hospital Oldenburg","ror":"https://ror.org/03avbdx23","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210125974"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Nicole M. Ziegler","raw_affiliation_strings":["Department of Obstetrics, Gynecology, and Gynecology Oncology, Pius Hospital, Oldenburg, 26121, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology, and Gynecology Oncology, Pius Hospital, Oldenburg, 26121, Germany","institution_ids":["https://openalex.org/I4210125974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077098140","display_name":"Matthias Korell","orcid":"https://orcid.org/0000-0001-9503-9052","observed_orcids":["https://orcid.org/0000-0001-9503-9052"]},"institutions":[{"id":"https://openalex.org/I4210123310","display_name":"Johanna-Etienne-Krankenhaus","ror":"https://ror.org/035btw704","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210123310"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias Korell","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Johanna Etienne Krankenhaus, Neuss, 41462, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Johanna Etienne Krankenhaus, Neuss, 41462, Germany","institution_ids":["https://openalex.org/I4210123310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034898434","display_name":"Henning Ritter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125974","display_name":"Pius Hospital Oldenburg","ror":"https://ror.org/03avbdx23","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210125974"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Henning Ritter","raw_affiliation_strings":["Department of Obstetrics, Gynecology, and Gynecology Oncology, Pius Hospital, Oldenburg, 26121, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology, and Gynecology Oncology, Pius Hospital, Oldenburg, 26121, Germany","institution_ids":["https://openalex.org/I4210125974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078354802","display_name":"Alex McConnachie","orcid":"https://orcid.org/0000-0002-7262-7000","observed_orcids":["https://orcid.org/0000-0002-7262-7000"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alex McConnachie","raw_affiliation_strings":["Robertson Centre for Biostatistics, University of Glasgow, Glasgow, G12 8QQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow, Glasgow, G12 8QQ, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016095791","display_name":"Ian Ford","orcid":"https://orcid.org/0000-0001-5927-1823","observed_orcids":["https://orcid.org/0000-0001-5927-1823"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ian Ford","raw_affiliation_strings":["Robertson Centre for Biostatistics, University of Glasgow, Glasgow, G12 8QQ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robertson Centre for Biostatistics, University of Glasgow, Glasgow, G12 8QQ, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024081773","display_name":"Alison M. Crowe","orcid":"https://orcid.org/0000-0003-2077-1227","observed_orcids":["https://orcid.org/0000-0003-2077-1227"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alison M. Crowe","raw_affiliation_strings":["Corvus Communications Ltd, East Sussex, TN22 4PB, UK"],"raw_orcid":"https://orcid.org/0000-0003-2077-1227","affiliations":[{"raw_affiliation_string":"Corvus Communications Ltd, East Sussex, TN22 4PB, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039308901","display_name":"Trudy D. Estridge","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Trudy D. Estridge","raw_affiliation_strings":["Actamax Surgical Materials LLC, Wilmington, DE, 19803, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Actamax Surgical Materials LLC, Wilmington, DE, 19803, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005306051","display_name":"Michael P. Diamond","orcid":"https://orcid.org/0000-0001-6353-4489","observed_orcids":["https://orcid.org/0000-0001-6353-4489"]},"institutions":[{"id":"https://openalex.org/I25041050","display_name":"Augusta University","ror":"https://ror.org/012mef835","country_code":"US","type":"education","lineage":["https://openalex.org/I25041050"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael P. Diamond","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Augusta University, Augusta, GA, 30912, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Augusta University, Augusta, GA, 30912, USA","institution_ids":["https://openalex.org/I25041050"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033949951","display_name":"Rudy Leon De Wilde","orcid":"https://orcid.org/0000-0001-5759-9745","observed_orcids":["https://orcid.org/0000-0001-5759-9745"]},"institutions":[{"id":"https://openalex.org/I4210125974","display_name":"Pius Hospital Oldenburg","ror":"https://ror.org/03avbdx23","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210125974"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rudy L. De Wilde","raw_affiliation_strings":["Department of Obstetrics, Gynecology, and Gynecology Oncology, Pius Hospital, Oldenburg, 26121, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology, and Gynecology Oncology, Pius Hospital, Oldenburg, 26121, Germany","institution_ids":["https://openalex.org/I4210125974"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5021353845"],"corresponding_institution_ids":["https://openalex.org/I2801748203"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":{"value":4590,"currency":"USD","value_usd":4590},"fwci":2.2932,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.87848138,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"295","issue":"2","first_page":"383","last_page":"395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12089","display_name":"Intestinal and Peritoneal Adhesions","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12089","display_name":"Intestinal and Peritoneal Adhesions","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10961","display_name":"Hernia repair and management","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12906","display_name":"Surgical Sutures and Adhesives","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postoperative-adhesions","display_name":"postoperative adhesions","score":0.9110000133514404},{"id":"https://openalex.org/keywords/anti-adhesion-barrier","display_name":"anti-adhesion barrier","score":0.8460000157356262},{"id":"https://openalex.org/keywords/biodegradable-hydrogels","display_name":"biodegradable hydrogels","score":0.9710000157356262},{"id":"https://openalex.org/keywords/gynecologic-laparoscopic-surgery","display_name":"gynecologic laparoscopic surgery","score":0.8759999871253967},{"id":"https://openalex.org/keywords/abdominopelvic-surgery","display_name":"abdominopelvic surgery","score":0.9559999704360962},{"id":"https://openalex.org/keywords/myomectomy","display_name":"myomectomy","score":0.8159999847412109},{"id":"https://openalex.org/keywords/second-look-laparoscopy","display_name":"second-look laparoscopy","score":0.949999988079071},{"id":"https://openalex.org/keywords/fertility-preservation","display_name":"fertility preservation","score":0.7929999828338623},{"id":"https://openalex.org/keywords/adhesion-score","display_name":"adhesion score","score":0.5730000138282776},{"id":"https://openalex.org/keywords/equipment-safety","display_name":"device safety","score":0.5410000085830688},{"id":"https://openalex.org/keywords/spray-application","display_name":"spray application","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9467053413391113},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7256124019622803},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.7147460579872131},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.6081945896148682},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5483395457267761},{"id":"https://openalex.org/C2780047204","wikidata":"https://www.wikidata.org/wiki/Q675754","display_name":"Laparoscopy","level":2,"score":0.5133801698684692},{"id":"https://openalex.org/C2776111594","wikidata":"https://www.wikidata.org/wiki/Q675754","display_name":"Laparoscopic surgery","level":3,"score":0.4817114472389221},{"id":"https://openalex.org/C2910947712","wikidata":"https://www.wikidata.org/wiki/Q2963982","display_name":"Gynecologic surgical procedures","level":3,"score":0.4574720859527588},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19730138778686523},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000267","descriptor_name":"Tissue Adhesions","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010535","descriptor_name":"Laparoscopy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013509","descriptor_name":"Gynecologic Surgical Procedures","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D020136","descriptor_name":"Hydrogel, Polyethylene Glycol Dimethacrylate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D063186","descriptor_name":"Uterine Myomectomy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s00404-016-4211-x","doi":"https://doi.org/10.1007/s00404-016-4211-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00404-016-4211-x","pdf_url":"https://link.springer.com/content/pdf/10.1007%2Fs00404-016-4211-x.pdf","source":{"id":"https://openalex.org/S568598","display_name":"Archives of Gynecology and Obstetrics","issn_l":"0003-9128","issn":["0003-9128","0170-9925","0932-0067","1432-0711"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Gynecology and Obstetrics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5281664","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5281664","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arch Gynecol Obstet","raw_type":"Text"},{"id":"pmid:27844212","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27844212","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of gynecology and obstetrics","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.gla.ac.uk:131443","doi":null,"is_oa":false,"landing_page_url":"http://eprints.gla.ac.uk/131443/7/131443.pdf","pdf_url":"http://eprints.gla.ac.uk/131443/7/131443.pdf","source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/I4405259220","host_organization_name":"Institut Agama Islam Negeri Langsa","host_organization_lineage":["https://openalex.org/I4405259220"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Articles"}],"best_oa_location":{"id":"doi:10.1007/s00404-016-4211-x","doi":"https://doi.org/10.1007/s00404-016-4211-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00404-016-4211-x","pdf_url":"https://link.springer.com/content/pdf/10.1007%2Fs00404-016-4211-x.pdf","source":{"id":"https://openalex.org/S568598","display_name":"Archives of Gynecology and Obstetrics","issn_l":"0003-9128","issn":["0003-9128","0170-9925","0932-0067","1432-0711"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Gynecology and Obstetrics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2551246501.pdf","grobid_xml":"https://content.openalex.org/works/W2551246501.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W16457125","https://openalex.org/W20139704","https://openalex.org/W29622879","https://openalex.org/W203209464","https://openalex.org/W933815316","https://openalex.org/W1210047938","https://openalex.org/W1885241008","https://openalex.org/W1969004742","https://openalex.org/W1971470712","https://openalex.org/W1973522661","https://openalex.org/W1979849615","https://openalex.org/W1984461602","https://openalex.org/W1992078572","https://openalex.org/W1996448749","https://openalex.org/W2001311766","https://openalex.org/W2032315642","https://openalex.org/W2043869910","https://openalex.org/W2044869556","https://openalex.org/W2065022899","https://openalex.org/W2066114225","https://openalex.org/W2068952767","https://openalex.org/W2072435204","https://openalex.org/W2094780755","https://openalex.org/W2095704740","https://openalex.org/W2098252755","https://openalex.org/W2102316427","https://openalex.org/W2113045030","https://openalex.org/W2116749486","https://openalex.org/W2124274780","https://openalex.org/W2130933276","https://openalex.org/W2151258395","https://openalex.org/W2153163774","https://openalex.org/W2154410358","https://openalex.org/W2167500010","https://openalex.org/W2170465797","https://openalex.org/W2171105659","https://openalex.org/W2238849319","https://openalex.org/W2399063085","https://openalex.org/W2410046882","https://openalex.org/W2418929963","https://openalex.org/W2463460449","https://openalex.org/W2464633884","https://openalex.org/W4233597078","https://openalex.org/W4241443014","https://openalex.org/W4245870469","https://openalex.org/W4252664856"],"related_works":["https://openalex.org/W2323736091","https://openalex.org/W2529944816","https://openalex.org/W2133279491","https://openalex.org/W2098252755","https://openalex.org/W2116749486","https://openalex.org/W1991482971","https://openalex.org/W1973522661","https://openalex.org/W2400460514","https://openalex.org/W3043445285","https://openalex.org/W2328965520"],"abstract_inverted_index":{"PURPOSE:":[0],"Post-surgical":[1],"adhesions":[2],"remain":[3],"a":[4,23,209,221,237],"significant":[5,256],"concern":[6],"following":[7,33,271],"abdominopelvic":[8,36,65,245],"surgery.":[9,37],"This":[10,39],"study":[11,48],"was":[12,49,138,147,186,247,263],"to":[13,28,58,87,116,179],"assess":[14],"safety,":[15],"manageability":[16],"and":[17,45,61,97,102,161,250],"explore":[18],"preliminary":[19],"efficacy":[20],"of":[21,30,81,94,168,236,254],"applying":[22],"degradable":[24,238],"hydrogel":[25,119,239,262],"adhesion":[26,206,240,268],"barrier":[27,241],"areas":[29],"surgical":[31,95],"trauma":[32],"gynecologic":[34,63,243],"laparoscopic":[35,64,244],"METHODS:":[38],"first-in-human,":[40],"prospective,":[41],"randomized,":[42],"multicenter,":[43],"subject-":[44],"reviewer-blinded":[46],"clinical":[47],"conducted":[50],"in":[51,181,201,265],"78":[52],"premenopausal":[53],"women":[54],"(18-46":[55],"years)":[56],"wishing":[57],"maintain":[59],"fertility":[60],"undergoing":[62],"surgery":[66,246],"with":[67,215,220],"planned":[68],"clinically":[69,255],"indicated":[70],"second-look":[71],"laparoscopy":[72],"(SLL)":[73],"at":[74,188],"4-12":[75],"weeks.":[76],"The":[77],"first":[78],"two":[79],"patients":[80],"each":[82],"surgeon":[83],"received":[84],"hydrogel,":[85],"up":[86],"30":[88],"mL":[89],"sprayed":[90],"over":[91],"all":[92],"sites":[93],"trauma,":[96],"were":[98,113,153],"assessed":[99,139],"for":[100,155,212],"safety":[101],"application":[103,235],"only":[104],"(n":[105,110,230],"=":[106,111,122,128,218,225,231],"12).":[107],"Subsequent":[108],"subjects":[109,158,193,229],"66)":[112],"randomized":[114,192],"1:1":[115],"receive":[117],"either":[118],"(Treatment,":[120],"n":[121,127],"35)":[123],"or":[124,142,149,176],"not":[125],"(Control,":[126],"31);":[129],"63":[130,191],"completed":[131,195],"the":[132,173,196,202,261],"SLL.":[133,189],"RESULTS:":[134],"No":[135],"adverse":[136,257],"event":[137],"as":[140],"serious,":[141],"possibly":[143],"device":[144,174],"related.":[145],"None":[146],"severe":[148],"fatal.":[150],"Adverse":[151],"events":[152],"reported":[154],"17":[156],"treated":[157,169],"(17/47,":[159],"36.2%)":[160],"13":[162],"Controls":[163,216],"(13/31,":[164],"41.9%).":[165],"For":[166,190],"95.7%":[167],"subjects,":[170],"surgeons":[171],"found":[172],"\"easy\"":[175],"\"very":[177],"easy\"":[178],"use;":[180],"54.5%,":[182],"some":[183],"residual":[184],"material":[185],"evident":[187],"who":[194],"SLL,":[197],"adjusted":[198],"between-group":[199],"difference":[200],"change":[203],"from":[204],"baseline":[205],"score":[207],"demonstrated":[208],"41.4%":[210],"reduction":[211,223],"Treatment":[213],"compared":[214],"(p":[217,224],"0.017),":[219],"49.5%":[222],"0.008)":[226],"among":[227],"myomectomy":[228],"34).":[232],"CONCLUSION:":[233],"Spray":[234],"during":[242],"performed":[248],"easily":[249],"safely,":[251],"without":[252],"evidence":[253],"outcomes.":[258],"Data":[259],"suggest":[260],"effective":[264],"reducing":[266],"postoperative":[267],"development,":[269],"particularly":[270],"myomectomy.":[272]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-11-30T00:00:00"}