{"id":"https://openalex.org/W2551020171","doi":"https://doi.org/10.1038/nature20170","title":"Control of mitochondrial function and cell growth by the atypical cadherin Fat1","display_name":"Control of mitochondrial function and cell growth by the atypical cadherin Fat1","publication_year":2016,"publication_date":"2016-11-01","ids":{"openalex":"https://openalex.org/W2551020171","doi":"https://doi.org/10.1038/nature20170","mag":"2551020171","pmid":"https://pubmed.ncbi.nlm.nih.gov/27828948","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5257202"},"language":"en","primary_location":{"id":"doi:10.1038/nature20170","doi":"https://doi.org/10.1038/nature20170","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nature20170","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5257202","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065612522","display_name":"Longyue L. Cao","orcid":"https://orcid.org/0000-0002-5209-2889","observed_orcids":["https://orcid.org/0000-0002-5209-2889"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Longyue L. Cao","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083730781","display_name":"Dario F. Riascos\u2010Bernal","orcid":"https://orcid.org/0000-0002-8790-4699","observed_orcids":["https://orcid.org/0000-0002-8790-4699"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dario F. Riascos-Bernal","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065409758","display_name":"Prameladevi Chinnasamy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prameladevi Chinnasamy","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086584560","display_name":"Charlene M. Dunaway","orcid":"https://orcid.org/0000-0002-1533-9344","observed_orcids":["https://orcid.org/0000-0002-1533-9344"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charlene M. Dunaway","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010225963","display_name":"Rong Hou","orcid":"https://orcid.org/0000-0002-8236-6318","observed_orcids":["https://orcid.org/0000-0002-8236-6318"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rong Hou","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Medicine (Cardiology), Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000703941","display_name":"Mario Andres Pujato","orcid":"https://orcid.org/0000-0002-2415-3111","observed_orcids":["https://orcid.org/0000-0002-2415-3111"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mario A. Pujato","raw_affiliation_strings":["Department of Systems &Computational Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Systems & Computational Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Systems &Computational Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Systems & Computational Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080198568","display_name":"Brian P O'Rourke","orcid":"https://orcid.org/0000-0002-5548-4853","observed_orcids":["https://orcid.org/0000-0002-5548-4853","https://orcid.org/0000-0002-0816-4443"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian P. O\u2019Rourke","raw_affiliation_strings":["Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022495942","display_name":"Veronika Miskolci","orcid":"https://orcid.org/0000-0001-7900-4626","observed_orcids":["https://orcid.org/0000-0001-7900-4626"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Veronika Miskolci","raw_affiliation_strings":["Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036175049","display_name":"Liang Guo","orcid":"https://orcid.org/0000-0003-1633-1544","observed_orcids":["https://orcid.org/0000-0003-1633-1544"]},"institutions":[{"id":"https://openalex.org/I4210135350","display_name":"CVPath Institute","ror":"https://ror.org/03gbzhd34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210135350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liang Guo","raw_affiliation_strings":["CVPath Institute, Gaithersburg, Maryland 20878, USA","CVPath Institute, Gaithersburg, 20878, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CVPath Institute, Gaithersburg, Maryland 20878, USA","institution_ids":["https://openalex.org/I4210135350"]},{"raw_affiliation_string":"CVPath Institute, Gaithersburg, 20878, Maryland, USA","institution_ids":["https://openalex.org/I4210135350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063009940","display_name":"Louis Hodgson","orcid":"https://orcid.org/0000-0001-9188-7580","observed_orcids":["https://orcid.org/0000-0001-9188-7580"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Louis Hodgson","raw_affiliation_strings":["Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040379692","display_name":"Andr\u00e1s Fiser","orcid":"https://orcid.org/0000-0003-0085-5335","observed_orcids":["https://orcid.org/0000-0003-0085-5335"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andras Fiser","raw_affiliation_strings":["Department of Systems &Computational Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Systems & Computational Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Systems &Computational Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Systems & Computational Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061886627","display_name":"Nicholas E. S. Sibinga","orcid":"https://orcid.org/0000-0003-4838-910X","observed_orcids":["https://orcid.org/0000-0003-4838-910X"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nicholas E. S. Sibinga","raw_affiliation_strings":["Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Wilf Family Cardiovascular Research Institute, Department of Medicine (Cardiology), Albert Einstein College of Medicine, Bronx, New York 10461, USA","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, 10461, New York, USA","institution_ids":["https://openalex.org/I129975664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5061886627"],"corresponding_institution_ids":["https://openalex.org/I129975664"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":2.6143,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.90829546,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"539","issue":"7630","first_page":"575","last_page":"578"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fat1","display_name":"FAT1","score":0.9890000224113464},{"id":"https://openalex.org/keywords/atypical-cadherin","display_name":"atypical cadherin","score":0.9660000205039978},{"id":"https://openalex.org/keywords/mitochondrial-respiration","display_name":"mitochondrial respiration","score":0.9089999794960022},{"id":"https://openalex.org/keywords/vascular-smooth-muscle-cells","display_name":"vascular smooth muscle cells","score":0.9649999737739563},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/arterial-injury","display_name":"arterial injury","score":0.9700000286102295},{"id":"https://openalex.org/keywords/neointimal-hyperplasia","display_name":"intimal hyperplasia","score":0.9010000228881836},{"id":"https://openalex.org/keywords/mitochondrial-supercomplexes","display_name":"mitochondrial supercomplexes","score":0.8199999928474426},{"id":"https://openalex.org/keywords/respiratory-chain-complexes","display_name":"respiratory chain complexes","score":0.6230000257492065},{"id":"https://openalex.org/keywords/aspartate","display_name":"aspartic acid","score":0.7519999742507935},{"id":"https://openalex.org/keywords/mitochondrial-metabolism","display_name":"mitochondrial metabolism","score":0.39899998903274536},{"id":"https://openalex.org/keywords/tissue-repair","display_name":"tissue repair","score":0.625},{"id":"https://openalex.org/keywords/cell-growth-regulation","display_name":"cell growth regulation","score":0.6309999823570251},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.6230000257492065},{"id":"https://openalex.org/keywords/atp-production","display_name":"ATP production","score":0.6399999856948853},{"id":"https://openalex.org/keywords/vascular-injury-response","display_name":"vascular injury response","score":0.38499999046325684}],"concepts":[{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.7662738561630249},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7262995839118958},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6222055554389954},{"id":"https://openalex.org/C149402561","wikidata":"https://www.wikidata.org/wiki/Q24776048","display_name":"Cadherin","level":3,"score":0.5575016140937805},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.49709418416023254},{"id":"https://openalex.org/C66517615","wikidata":"https://www.wikidata.org/wiki/Q912751","display_name":"Cellular respiration","level":3,"score":0.4514467120170593},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.4509451389312744},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4081442952156067},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2683030962944031}],"mesh":[{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001158","descriptor_name":"Arteries","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D001158","descriptor_name":"Arteries","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D001158","descriptor_name":"Arteries","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001224","descriptor_name":"Aspartic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015820","descriptor_name":"Cadherins","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D015820","descriptor_name":"Cadherins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015820","descriptor_name":"Cadherins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019069","descriptor_name":"Cell Respiration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051336","descriptor_name":"Mitochondrial Membranes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055786","descriptor_name":"Gene Knockout Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058426","descriptor_name":"Neointima","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/nature20170","doi":"https://doi.org/10.1038/nature20170","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nature20170","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:27828948","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27828948","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4289882","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5257202","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5257202","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5257202","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nature","raw_type":"Text"},{"id":"pmh:oai:RePEc:nat:nature:v:539:y:2016:i:7630:d:10.1038_nature20170","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/nature20170","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4289882","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5257202","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2401041598","display_name":"The Fat1 Cadherin in Atherosclerotic Vascular Disease","funder_award_id":"R01HL104518","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2446474187","display_name":"Roles of formins in breast cancer invasion","funder_award_id":"R21CA205262","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2870262525","display_name":"The Fat1 Cadherin and Vascular Remodeling","funder_award_id":"R01HL088104","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7764720279","display_name":"Training Program in Cellular and Molecular Biology and Genetics","funder_award_id":"T32GM007491","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G788956770","display_name":"Diabetes Research and Training Center","funder_award_id":"P60DK020541","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G87033130","display_name":"Medical Scientist Training Program","funder_award_id":"T32GM007288","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000867824","display_name":"New York Obesity Research Center","funder_award_id":"P30DK026687","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000877850","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA013330","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W1485557566","https://openalex.org/W1553978925","https://openalex.org/W1611787727","https://openalex.org/W1777916189","https://openalex.org/W1838945435","https://openalex.org/W1932780354","https://openalex.org/W1970253192","https://openalex.org/W1971176522","https://openalex.org/W1973743644","https://openalex.org/W1977385837","https://openalex.org/W1985990508","https://openalex.org/W2000860171","https://openalex.org/W2005154637","https://openalex.org/W2006849545","https://openalex.org/W2009715420","https://openalex.org/W2014691356","https://openalex.org/W2016557812","https://openalex.org/W2017901652","https://openalex.org/W2018912420","https://openalex.org/W2021713077","https://openalex.org/W2021910662","https://openalex.org/W2025138353","https://openalex.org/W2029261498","https://openalex.org/W2047242190","https://openalex.org/W2052563744","https://openalex.org/W2057508202","https://openalex.org/W2059673309","https://openalex.org/W2061164005","https://openalex.org/W2064689563","https://openalex.org/W2067393680","https://openalex.org/W2070482948","https://openalex.org/W2087234818","https://openalex.org/W2093844155","https://openalex.org/W2094808103","https://openalex.org/W2097948046","https://openalex.org/W2098553470","https://openalex.org/W2102774255","https://openalex.org/W2108837879","https://openalex.org/W2110112605","https://openalex.org/W2113613985","https://openalex.org/W2121520913","https://openalex.org/W2121822802","https://openalex.org/W2127675410","https://openalex.org/W2128036243","https://openalex.org/W2130106722","https://openalex.org/W2133002620","https://openalex.org/W2133572194","https://openalex.org/W2137424160","https://openalex.org/W2140653951","https://openalex.org/W2141122353","https://openalex.org/W2143505819","https://openalex.org/W2143892509","https://openalex.org/W2152951302","https://openalex.org/W2153821641","https://openalex.org/W2157266730","https://openalex.org/W2158217645","https://openalex.org/W2160489836","https://openalex.org/W2161952636","https://openalex.org/W2166886529","https://openalex.org/W2167612797","https://openalex.org/W2168750058","https://openalex.org/W2168754435","https://openalex.org/W2171991500","https://openalex.org/W2289592036","https://openalex.org/W2405770350","https://openalex.org/W2486083933"],"related_works":["https://openalex.org/W2521792569","https://openalex.org/W2556415570","https://openalex.org/W2200336349","https://openalex.org/W4280639153","https://openalex.org/W3047898877","https://openalex.org/W3197754625","https://openalex.org/W2965219529","https://openalex.org/W2947637603","https://openalex.org/W2005154637","https://openalex.org/W807222498"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-11-30T00:00:00"}