{"id":"https://openalex.org/W2548878692","doi":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","title":"Removal of oxidatively generated DNA damage by overlapping repair pathways","display_name":"Removal of oxidatively generated DNA damage by overlapping repair pathways","publication_year":2016,"publication_date":"2016-11-03","ids":{"openalex":"https://openalex.org/W2548878692","doi":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","mag":"2548878692","pmid":"https://pubmed.ncbi.nlm.nih.gov/27818219","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5418118"},"language":"en","primary_location":{"id":"doi:10.1016/j.freeradbiomed.2016.10.507","doi":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","pdf_url":null,"source":{"id":"https://openalex.org/S128018148","display_name":"Free Radical Biology and Medicine","issn_l":"0891-5849","issn":["0891-5849","1873-4596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Free Radical Biology and Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068343349","display_name":"Vladimir Shafirovich","orcid":"https://orcid.org/0000-0001-8225-6509","observed_orcids":["https://orcid.org/0000-0001-8225-6509"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Vladimir Shafirovich","raw_affiliation_strings":["Chemistry Department, New York University, 31 Washington Place, New York, NY 10003-5180, USA. Electronic address: vs5@nyu.edu","Chemistry Department, New York University, 31 Washington Place, New York, NY 10003-5180, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Department, New York University, 31 Washington Place, New York, NY 10003-5180, USA. Electronic address: vs5@nyu.edu","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Chemistry Department, New York University, 31 Washington Place, New York, NY 10003-5180, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018460703","display_name":"Nicholas E. Geacintov","orcid":"https://orcid.org/0000-0002-7961-2231","observed_orcids":["https://orcid.org/0000-0002-7961-2231"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas E. Geacintov","raw_affiliation_strings":["Chemistry Department, New York University, 31 Washington Place, New York, NY 10003-5180, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemistry Department, New York University, 31 Washington Place, New York, NY 10003-5180, USA","institution_ids":["https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5068343349"],"corresponding_institution_ids":["https://openalex.org/I57206974"],"apc_list":{"value":4240,"currency":"USD","value_usd":4240},"apc_paid":null,"fwci":0.6041,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.52848379,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"107","issue":null,"first_page":"53","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nucleotide-excision-repair","display_name":"nucleotide excision repair","score":0.8740000128746033},{"id":"https://openalex.org/keywords/base-excision-repair","display_name":"base excision repair","score":1.0},{"id":"https://openalex.org/keywords/dna-repair-pathways","display_name":"DNA repair pathways","score":0.5839999914169312},{"id":"https://openalex.org/keywords/guanine-oxidation","display_name":"guanine oxidation","score":0.9200000166893005},{"id":"https://openalex.org/keywords/spiroiminodihydantoin","display_name":"spiroiminodihydantoin","score":0.9049999713897705},{"id":"https://openalex.org/keywords/peroxynitrite","display_name":"peroxynitrite","score":0.9850000143051147},{"id":"https://openalex.org/keywords/intrastrand-cross-links","display_name":"intrastrand cross-links","score":0.7039999961853027},{"id":"https://openalex.org/keywords/bulky-dna-lesions","display_name":"bulky DNA lesions","score":0.6669999957084656}],"concepts":[{"id":"https://openalex.org/C2778301229","wikidata":"https://www.wikidata.org/wiki/Q169313","display_name":"Guanine","level":4,"score":0.848400354385376},{"id":"https://openalex.org/C104451858","wikidata":"https://www.wikidata.org/wiki/Q2714458","display_name":"Nucleotide excision repair","level":4,"score":0.8150851726531982},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.6821334362030029},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.640864372253418},{"id":"https://openalex.org/C187206112","wikidata":"https://www.wikidata.org/wiki/Q3113091","display_name":"Base excision repair","level":4,"score":0.6228962540626526},{"id":"https://openalex.org/C2778784160","wikidata":"https://www.wikidata.org/wiki/Q419130","display_name":"Peroxynitrite","level":4,"score":0.5986976623535156},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.5944928526878357},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.5337432622909546},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.5104557275772095},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4453241229057312},{"id":"https://openalex.org/C2778530040","wikidata":"https://www.wikidata.org/wiki/Q1937315","display_name":"Helix (gastropod)","level":3,"score":0.4269281327724457},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3641098141670227},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.35152363777160645},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22710001468658447},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.15834316611289978},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1209779679775238},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C2779965526","wikidata":"https://www.wikidata.org/wiki/Q308841","display_name":"Snail","level":2,"score":0.0},{"id":"https://openalex.org/C2780795997","wikidata":"https://www.wikidata.org/wiki/Q413283","display_name":"Superoxide","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006146","descriptor_name":"Guanidines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006827","descriptor_name":"Hydantoins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009593","descriptor_name":"Nitroimidazoles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045647","descriptor_name":"DNA Glycosylases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D059371","descriptor_name":"DNA, B-Form","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059371","descriptor_name":"DNA, B-Form","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.freeradbiomed.2016.10.507","doi":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","pdf_url":null,"source":{"id":"https://openalex.org/S128018148","display_name":"Free Radical Biology and Medicine","issn_l":"0891-5849","issn":["0891-5849","1873-4596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Free Radical Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:27818219","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27818219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Free radical biology & medicine","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4926484","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5418118","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5418118","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5418118","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Free Radic Biol Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.freeradbiomed.2016.10.507","doi":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.freeradbiomed.2016.10.507","pdf_url":null,"source":{"id":"https://openalex.org/S128018148","display_name":"Free Radical Biology and Medicine","issn_l":"0891-5849","issn":["0891-5849","1873-4596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Free Radical Biology and Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1181673059","display_name":"SHARED INSTR FACILITIY FOR THE LIFE SCI","funder_award_id":"C06RR016572","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G2489213757","display_name":"Interplay between DNA repair mechanisms in human cells and extracts","funder_award_id":"R01ES027059","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G6746365051","display_name":"MRI-R2: Acquisition of a MALDI-TOF Mass Spectrometer","funder_award_id":"0958457","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G977929771","display_name":"Recognition of Environmental Carcinogen-DNA lesions by NER Proteins","funder_award_id":"R01ES024050","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":123,"referenced_works":["https://openalex.org/W131259078","https://openalex.org/W263493038","https://openalex.org/W1504132186","https://openalex.org/W1514802418","https://openalex.org/W1536009735","https://openalex.org/W1845715719","https://openalex.org/W1948333092","https://openalex.org/W1949858629","https://openalex.org/W1965037168","https://openalex.org/W1967839472","https://openalex.org/W1968988021","https://openalex.org/W1969314103","https://openalex.org/W1972094156","https://openalex.org/W1973428256","https://openalex.org/W1974691766","https://openalex.org/W1974989751","https://openalex.org/W1975485903","https://openalex.org/W1976987484","https://openalex.org/W1979819873","https://openalex.org/W1981076720","https://openalex.org/W1981912201","https://openalex.org/W1981981729","https://openalex.org/W1984532604","https://openalex.org/W1985154852","https://openalex.org/W1985323804","https://openalex.org/W1986406178","https://openalex.org/W1987954870","https://openalex.org/W1989400378","https://openalex.org/W1989933301","https://openalex.org/W1991189413","https://openalex.org/W1991615875","https://openalex.org/W1991897336","https://openalex.org/W1993995910","https://openalex.org/W1995651421","https://openalex.org/W1997060740","https://openalex.org/W1997899666","https://openalex.org/W2000664718","https://openalex.org/W2001362843","https://openalex.org/W2004191494","https://openalex.org/W2005845362","https://openalex.org/W2005905897","https://openalex.org/W2007043238","https://openalex.org/W2012930199","https://openalex.org/W2016134181","https://openalex.org/W2016773562","https://openalex.org/W2016774853","https://openalex.org/W2016844537","https://openalex.org/W2018357442","https://openalex.org/W2018909475","https://openalex.org/W2019580536","https://openalex.org/W2019646037","https://openalex.org/W2021241545","https://openalex.org/W2022051063","https://openalex.org/W2025375305","https://openalex.org/W2026273332","https://openalex.org/W2026838497","https://openalex.org/W2027048245","https://openalex.org/W2030666445","https://openalex.org/W2032126854","https://openalex.org/W2034414992","https://openalex.org/W2035311142","https://openalex.org/W2036676014","https://openalex.org/W2040530338","https://openalex.org/W2040825860","https://openalex.org/W2040843368","https://openalex.org/W2041834340","https://openalex.org/W2045910186","https://openalex.org/W2046082575","https://openalex.org/W2050224588","https://openalex.org/W2051962365","https://openalex.org/W2052991677","https://openalex.org/W2053861316","https://openalex.org/W2055092548","https://openalex.org/W2058044047","https://openalex.org/W2058659691","https://openalex.org/W2058793561","https://openalex.org/W2058852955","https://openalex.org/W2060849212","https://openalex.org/W2061224795","https://openalex.org/W2061625987","https://openalex.org/W2061764665","https://openalex.org/W2061919040","https://openalex.org/W2064576961","https://openalex.org/W2065545028","https://openalex.org/W2066200970","https://openalex.org/W2066386477","https://openalex.org/W2068407072","https://openalex.org/W2070661653","https://openalex.org/W2070888848","https://openalex.org/W2074020290","https://openalex.org/W2075383386","https://openalex.org/W2077164511","https://openalex.org/W2077450957","https://openalex.org/W2078705269","https://openalex.org/W2081201480","https://openalex.org/W2082683256","https://openalex.org/W2084369408","https://openalex.org/W2085474714","https://openalex.org/W2087290238","https://openalex.org/W2087753682","https://openalex.org/W2088814535","https://openalex.org/W2088876058","https://openalex.org/W2090219305","https://openalex.org/W2102829872","https://openalex.org/W2104896412","https://openalex.org/W2113912029","https://openalex.org/W2118278569","https://openalex.org/W2121870234","https://openalex.org/W2125667702","https://openalex.org/W2133980314","https://openalex.org/W2141451936","https://openalex.org/W2163392206","https://openalex.org/W2169186429","https://openalex.org/W2170298709","https://openalex.org/W2232961728","https://openalex.org/W2236951518","https://openalex.org/W2274602515","https://openalex.org/W2315205964","https://openalex.org/W2316039752","https://openalex.org/W2437313603","https://openalex.org/W2465729593","https://openalex.org/W2587361973","https://openalex.org/W6669972691"],"related_works":["https://openalex.org/W2232961728","https://openalex.org/W2911479564","https://openalex.org/W3133687763","https://openalex.org/W3120399901","https://openalex.org/W2001362843","https://openalex.org/W2011814469","https://openalex.org/W1987759758","https://openalex.org/W1994123067","https://openalex.org/W82138205","https://openalex.org/W3016454999"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-11-11T00:00:00"}