{"id":"https://openalex.org/W2531748257","doi":null,"title":"Bedeutung regulierter Zelltodprogramme f\u00fcr die Transplantation solider Organe","display_name":"Bedeutung regulierter Zelltodprogramme f\u00fcr die Transplantation solider Organe","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2531748257","mag":"2531748257"},"language":"de","primary_location":{"id":"mag:2531748257","doi":null,"is_oa":false,"landing_page_url":"http://link.springer.com/content/pdf/10.1007/s11560-014-0914-9.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054170943","display_name":"Innere Medizin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Innere Medizin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5053398470","display_name":"Martin G. Zeier","orcid":"https://orcid.org/0000-0003-1700-959X","observed_orcids":["https://orcid.org/0000-0003-1700-959X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin Zeier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18701223,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.5268999934196472,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.5268999934196472,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.36230000853538513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.042100001126527786,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/regulated-cell-death","display_name":"regulated cell death","score":0.906000018119812},{"id":"https://openalex.org/keywords/solid-organ-transplantation","display_name":"solid organ transplantation","score":0.8600000143051147},{"id":"https://openalex.org/keywords/pyroptosis","display_name":"pyroptosis","score":0.9919999837875366},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/regulated-necrosis","display_name":"regulated necrosis","score":0.7620000243186951},{"id":"https://openalex.org/keywords/inflammasome","display_name":"inflammasome","score":0.8579999804496765},{"id":"https://openalex.org/keywords/damage-associated-molecular-patterns","display_name":"damage-associated molecular patterns","score":0.9399999976158142},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.800000011920929},{"id":"https://openalex.org/keywords/il-18","display_name":"IL-18","score":0.996999979019165},{"id":"https://openalex.org/keywords/caspases","display_name":"caspases","score":0.9210000038146973}],"concepts":[{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.379852294921875},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30297142267227173}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2531748257","doi":null,"is_oa":false,"landing_page_url":"http://link.springer.com/content/pdf/10.1007/s11560-014-0914-9.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1548775239","https://openalex.org/W1548929234","https://openalex.org/W1847056372","https://openalex.org/W1909274503","https://openalex.org/W1966977448","https://openalex.org/W1967493141","https://openalex.org/W1969323641","https://openalex.org/W1979032223","https://openalex.org/W1987186266","https://openalex.org/W1991997670","https://openalex.org/W2002490399","https://openalex.org/W2011538447","https://openalex.org/W2021051229","https://openalex.org/W2024591203","https://openalex.org/W2047135607","https://openalex.org/W2052605153","https://openalex.org/W2060204808","https://openalex.org/W2062110054","https://openalex.org/W2068619092","https://openalex.org/W2069250210","https://openalex.org/W2074892323","https://openalex.org/W2078141613","https://openalex.org/W2081053802","https://openalex.org/W2087232320","https://openalex.org/W2089503694","https://openalex.org/W2101800432","https://openalex.org/W2109718015","https://openalex.org/W2115273524","https://openalex.org/W2120626244","https://openalex.org/W2132161879","https://openalex.org/W2139552156","https://openalex.org/W2145149316","https://openalex.org/W2153298328","https://openalex.org/W2170872320"],"related_works":["https://openalex.org/W4237441880","https://openalex.org/W2001360142","https://openalex.org/W1891826181","https://openalex.org/W4306165642","https://openalex.org/W4400593199","https://openalex.org/W2883140341","https://openalex.org/W3207663138","https://openalex.org/W4366352165","https://openalex.org/W1536894704","https://openalex.org/W4310367054"],"abstract_inverted_index":{"der":[0,15,39,48,64],"Pyroptose":[1,29,80],"aktive":[2],"Caspasen":[3],"ins":[4],"Interstitium":[5],"freigesetzt,":[6],"um":[7],"dort":[8],"extrazellulare":[9,74],"Zytokinausreifung":[10,75],"zu":[11],"bewirken.":[12],"Wahrend":[13],"bei":[14,61],"Apoptose":[16],"die":[17,28,73],"Plasmamembran":[18,40],"intakt":[19],"bleibt":[20],"und":[21,41,78,103],"damit":[22,43],"keine":[23],"Entzundungsreaktion":[24],"hervorgerufen":[25,105],"wird,":[26],"ist":[27],"im":[30,58,99],"doppelten":[31],"Sinne":[32],"immunogen:":[33],"F":[34,68],"Erstens":[35],"wegen":[36],"des":[37],"Einreisens":[38],"dem":[42],"verbundenen":[44],"explosionsartigen,":[45],"hochdynamischen":[46],"Prozess":[47],"Verteilung":[49],"immunogener":[50],"intrazellularer":[51],"Bestandteile":[52],"(\u201edanger-associated":[53],"molecular":[54],"patterns\u201c,":[55],"DAMP),":[56],"welcher":[57],"Ubri":[59],"gen":[60],"allen":[62],"Signalwegen":[63],"regulierten":[65],"Nekrose":[66],"stattfindet.":[67],"Zweitens":[69],"aber":[70],"auch":[71],"durch":[72,82,93],"von":[76,84,101],"IL1b":[77],"IL-18.":[79],"wird":[81,106],"Aktivierung":[83],"sog.":[85],"Inflammasomen":[86],"ausgelost,":[87],"ein":[88],"Ereignis,":[89],"welches":[90],"z.":[91],"B.":[92,98],"Lipopolysaccharide":[94],"(LPS),":[95],"Kristalle":[96],"(z.":[97],"Rahmen":[100],"Gicht)":[102],"Silikate":[104],"[12,":[107],"13].":[108]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-10-21T00:00:00"}