{"id":"https://openalex.org/W2531583979","doi":"https://doi.org/10.1182/blood.v110.11.3967.3967","title":"Management of Hemophilia and Head Trauma: A Survey of Current Clinical Practice among Pediatric Hematology/Oncology Physicians.","display_name":"Management of Hemophilia and Head Trauma: A Survey of Current Clinical Practice among Pediatric Hematology/Oncology Physicians.","publication_year":2007,"publication_date":"2007-11-16","ids":{"openalex":"https://openalex.org/W2531583979","doi":"https://doi.org/10.1182/blood.v110.11.3967.3967","mag":"2531583979"},"language":"en","primary_location":{"id":"doi:10.1182/blood.v110.11.3967.3967","doi":"https://doi.org/10.1182/blood.v110.11.3967.3967","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v110.11.3967.3967","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064630175","display_name":"Char M. Witmer","orcid":"https://orcid.org/0000-0002-9551-4068","observed_orcids":["https://orcid.org/0000-0002-9551-4068"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Char M. Witmer","raw_affiliation_strings":["Pediatrics, The Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, The Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056348530","display_name":"Leslie J. Raffini","orcid":"https://orcid.org/0000-0001-8152-1040","observed_orcids":["https://orcid.org/0000-0001-8152-1040"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leslie J. Raffini","raw_affiliation_strings":["Pediatrics, The Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, The Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008625980","display_name":"Catherine Scott Manno","orcid":"https://orcid.org/0000-0001-8029-0391","observed_orcids":["https://orcid.org/0000-0001-8029-0391"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine S. Manno","raw_affiliation_strings":["Pediatrics, The Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics, The Children\u2019s Hospital of Philadelphia, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1335321130"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1335321130"],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.32907098,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"110","issue":"11","first_page":"3967","last_page":"3967"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemophilia","display_name":"hemophilia","score":0.968999981880188},{"id":"https://openalex.org/keywords/head-trauma","display_name":"head trauma","score":0.9160000085830688},{"id":"https://openalex.org/keywords/intracranial-hemorrhage","display_name":"intracranial hemorrhage","score":0.9300000071525574},{"id":"https://openalex.org/keywords/pediatric-hematology","display_name":"pediatric hematology","score":0.5559999942779541},{"id":"https://openalex.org/keywords/practice-patterns","display_name":"clinical practice patterns","score":0.7250000238418579},{"id":"https://openalex.org/keywords/institutional-protocols","display_name":"institutional protocols","score":0.5210000276565552},{"id":"https://openalex.org/keywords/prophylaxis","display_name":"prophylaxis","score":0.7120000123977661},{"id":"https://openalex.org/keywords/computed-tomography","display_name":"computed tomography","score":0.8650000095367432},{"id":"https://openalex.org/keywords/clinical-decision-making","display_name":"clinical decision-making","score":0.8029999732971191},{"id":"https://openalex.org/keywords/mechanism-of-injury","display_name":"injury mechanisms","score":0.703000009059906},{"id":"https://openalex.org/keywords/case-scenarios","display_name":"case scenarios","score":0.5709999799728394},{"id":"https://openalex.org/keywords/physician-survey","display_name":"physician survey","score":0.4399999976158142},{"id":"https://openalex.org/keywords/vomiting","display_name":"vomiting","score":0.3630000054836273},{"id":"https://openalex.org/keywords/hematoma","display_name":"hematoma","score":0.39500001072883606},{"id":"https://openalex.org/keywords/institutional-review-board-approval","display_name":"institutional review board approval","score":0.33799999952316284},{"id":"https://openalex.org/keywords/informed-consent","display_name":"informed consent","score":0.3009999990463257}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.908406674861908},{"id":"https://openalex.org/C3019520628","wikidata":"https://www.wikidata.org/wiki/Q2920572","display_name":"Head trauma","level":2,"score":0.6011769771575928},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.49051326513290405},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.46565061807632446},{"id":"https://openalex.org/C2777975874","wikidata":"https://www.wikidata.org/wiki/Q2920572","display_name":"Head injury","level":2,"score":0.44709673523902893},{"id":"https://openalex.org/C2778242525","wikidata":"https://www.wikidata.org/wiki/Q1340307","display_name":"Toddler","level":2,"score":0.41515910625457764},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3553212583065033},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.28210464119911194},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2812274694442749},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1182/blood.v110.11.3967.3967","doi":"https://doi.org/10.1182/blood.v110.11.3967.3967","is_oa":false,"landing_page_url":"https://doi.org/10.1182/blood.v110.11.3967.3967","pdf_url":null,"source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2114030673","https://openalex.org/W4282982238","https://openalex.org/W2806783697","https://openalex.org/W2128511853","https://openalex.org/W1998438175","https://openalex.org/W1992349977","https://openalex.org/W7221750133","https://openalex.org/W4200442529","https://openalex.org/W2090686856","https://openalex.org/W1969699816"],"abstract_inverted_index":{"Abstract":[0],"OBJECTIVE:":[1],"The":[2,42,48,73,104,118,160,247,295,467],"goal":[3],"of":[4,19,41,45,77,128,153,157,228,260,264,268,273,285,472,486,492,506,556,564],"this":[5],"survey":[6],"was":[7,34,167,276],"to":[8,39,57,80,92,110,141,163,231,281,302,312,330,354,404,427,509,553],"assess":[9,111],"current":[10,468],"pediatric":[11,20,58,473],"hematologists/oncologists":[12],"self":[13,469],"reported":[14,224,470,489,548],"practices":[15],"regarding":[16,53],"the":[17,54,113,126,143,151,164,171,182,225,258,271,282,299,303,309,313,318,487,490,510,561],"management":[18,67,115],"patients":[21,59,177,209,233,474,572],"with":[22,60,83,178,234,323,397,475,573],"hemophilia":[23,61,85,179,195,235,325,399,476],"who":[24,477,513],"experience":[25],"head":[26,63,135,197,237,327,401,480,500,523,569],"trauma.":[27,198],"PATIENTS":[28],"AND":[29],"METHODS:":[30],"An":[31],"email":[32,165],"questionnaire":[33,49,166],"sent":[35],"on":[36,149],"March":[37],"2007":[38],"members":[40],"American":[43],"Society":[44],"Pediatric":[46],"Hematology/Oncology.":[47],"included":[50,120,257],"generalized":[51],"questions":[52,68],"clinical":[55,251,254,315,532],"approach":[56],"and":[62,65,86,180,196,210,236,262,270,326,400,495,543],"trauma":[64,136,328,402,481,501,524,570],"specific":[66,283],"for":[69,176,194,205,253,498,537],"two":[70],"case":[71,74,105,305],"scenarios.":[72],"scenarios":[75,106,306],"consisted":[76],"boys":[78],"(16":[79],"18":[81],"months)":[82],"severe":[84,324,398],"either":[87],"a":[88,96,121,146,331,405,526,554],"fall":[89,97,332,406],"from":[90,333,407],"2":[91],"3":[93],"feet":[94,335],"or":[95,504,517],"while":[98],"running;":[99],"both":[100],"were":[101,107],"well":[102],"appearing.":[103],"then":[108],"altered":[109],"if":[112],"physicians":[114],"would":[116,514],"change.":[117],"alterations":[119],"large":[122],"palpable":[123],"hematoma":[124],"at":[125,150],"sight":[127],"injury,":[129,154],"prophylaxis":[130],"administered":[131],"24":[132],"hours":[133,139,345,418],"prior,":[134],"occurred":[137],"48":[138,344,417],"prior":[140,266,346,419],"evaluation,":[142],"patient":[144],"had":[145,242],"soft":[147,203,215],"helmet":[148,349],"time":[152],"one":[155],"episode":[156],"emesis.":[158],"RESULTS:":[159],"response":[161,301,311],"rate":[162],"37%,":[168],"397/1077.":[169],"Of":[170],"397":[172],"respondents":[173,488,512],"252":[174],"cared":[175],"completed":[181],"survey.":[183],"Twenty-eight":[184],"percent":[185,222,300,310],"(69/251)":[186],"indicated":[187,213],"that":[188,214,287,558],"they":[189],"utilized":[190],"an":[191,292],"institutional":[192],"protocol":[193],"Only":[199],"33%":[200],"(82/250)":[201],"recommend":[202],"helmets":[204,216],"their":[206],"toddler":[207],"age":[208],"28%":[211],"(67/241)":[212],"could":[217],"prevent":[218],"intracranial":[219,293],"bleeding.":[220],"Eighty-nine":[221],"(220/248)":[223],"routine":[226],"use":[227,491],"computed":[229],"tomography":[230],"evaluate":[232],"trauma,":[238],"although":[239],"41%":[240],"(102/250)":[241],"concerns":[243],"about":[244],"CT":[245,376,449,496],"imaging.":[246],"respondent\u2019s":[248],"highest":[249],"ranked":[250],"variables":[252],"decision":[255],"making":[256],"presence":[259],"signs":[261,503],"symptoms":[263,505],"ICH,":[265,269],"history":[267],"mechanism":[272,284],"injury.":[274],"There":[275],"no":[277],"clear":[278],"consensus":[279],"as":[280],"injury":[286],"most":[288],"likely":[289,551],"results":[290],"in":[291,317,529,547,571],"hemorrhage.":[294],"tables":[296],"below":[297],"demonstrate":[298],"initial":[304],"followed":[307],"by":[308],"specified":[314],"change":[316],"case:":[319],"Case":[320,336,394,409],"#1.":[321],"Toddler":[322,396],"due":[329,403],"2\u20133":[334],"#1":[337],"1)":[338,411],"Bruise":[339,412],"2)":[340,413],"Prophylaxis":[341,414],"3)":[342,415],"Injury":[343,416],"4)":[347,420],"Soft":[348,421],"5)":[350,423],"Emesis":[351,424],"(Represents":[352,425],"230":[353],"239":[355],"respondents)":[356],"No":[357,375,384,430,448,457],"Intervention":[358,431],"(%)":[359,367,377,387,432,440,450,459],"5.9":[360],"0.8":[361],"14.5":[362],"67.9":[363],"17.4":[364],"2.9":[365],"+Factor+CT":[366,439],"64.7":[368],"80.3":[369],"53":[370],"8.0":[371],"52.6":[372],"88.3":[373],"+Factor":[374,447],"25.2":[378],"15.5":[379],"24.8":[380],"21.5":[381],"23":[382],"4.2":[383,388],"factor":[385,493,520],"+CT":[386],"3.4":[389],"7.7":[390],"2.6":[391],"7":[392],"4.6":[393,460],"#2.":[395],"running.":[408],"#2":[410],"Helmet":[422],"205":[426],"220":[428],"respondents.)":[429],"18.6":[433],"1.9":[434],"20.9":[435],"66.4":[436],"27.8":[437],"3.7":[438],"51.8":[441],"79.5":[442],"48.3":[443],"8.5":[444],"44.4":[445],"84.2":[446],"25":[451],"15.3":[452],"23.7":[453],"7.6":[454],"21":[455],"5.6":[456],"factor+CT":[458],"3.3":[461],"7.1":[462],"17.5":[463],"6.8":[464],"6.5":[465],"CONCLUSIONS:":[466],"care":[471,549],"sustain":[478],"mild":[479,499,568],"is":[482,525,550,566],"diverse.":[483],"Over":[484],"half":[485],"replacement":[494],"imaging":[497],"without":[502],"ICH":[507,565],"compared":[508],"remaining":[511],"not":[515],"intervene":[516],"only":[518],"give":[519],"replacement.":[521],"Mild":[522],"common":[527],"event":[528],"childhood.":[530],"This":[531,545],"variation":[533],"has":[534],"significant":[535],"implications":[536],"individual":[538],"radiation":[539],"exposure,":[540],"sedation":[541],"risks,":[542],"cost.":[544],"diversity":[546],"secondary":[552],"lack":[555],"studies":[557],"address":[559],"what":[560],"true":[562],"risk":[563],"after":[567],"hemophilia.":[574]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-10-21T00:00:00"}