{"id":"https://openalex.org/W2530367609","doi":null,"title":"A 2016 panorama of Helicobacter pylori infection: key messages for clinicians.","display_name":"A 2016 panorama of Helicobacter pylori infection: key messages for clinicians.","publication_year":2016,"publication_date":"2016-12-01","ids":{"openalex":"https://openalex.org/W2530367609","mag":"2530367609","pmid":"https://pubmed.ncbi.nlm.nih.gov/27716738"},"language":"en","primary_location":{"id":"pmid:27716738","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27716738","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Panminerva medica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033132010","display_name":"Rinaldo Pellicano","orcid":"https://orcid.org/0000-0003-3438-0649","observed_orcids":["https://orcid.org/0000-0003-3438-0649"]},"institutions":[{"id":"https://openalex.org/I4210096532","display_name":"Fondazione Ricerca Molinette","ror":"https://ror.org/01mhzrb93","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210096532"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rinaldo Pellicano","raw_affiliation_strings":["Unit of Gastroenterology, Molinette Hospital, Turin, Italy - rinaldo_pellican@hotmail.com","Unit of Gastroenterology, Molinette Hospital, Turin, Italy -"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit of Gastroenterology, Molinette Hospital, Turin, Italy - rinaldo_pellican@hotmail.com","institution_ids":[]},{"raw_affiliation_string":"Unit of Gastroenterology, Molinette Hospital, Turin, Italy -","institution_ids":["https://openalex.org/I4210096532"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079090669","display_name":"Davide Giuseppe Ribaldone","orcid":"https://orcid.org/0000-0002-9421-3087","observed_orcids":["https://orcid.org/0000-0002-9421-3087"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Davide G Ribaldone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088189396","display_name":"Sharmila Fagoonee","orcid":"https://orcid.org/0000-0001-6070-6716","observed_orcids":["https://orcid.org/0000-0001-6070-6716"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sharmila Fagoonee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036406339","display_name":"Marco Astegiano","orcid":"https://orcid.org/0000-0003-0916-1188","observed_orcids":["https://orcid.org/0000-0003-0916-1188"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco Astegiano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089401525","display_name":"Giorgio Maria Saracco","orcid":"https://orcid.org/0000-0001-5310-4143","observed_orcids":["https://orcid.org/0000-0001-5310-4143"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giorgio M Saracco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5050209583","display_name":"Fran\u00e7is M\u00e9graud","orcid":"https://orcid.org/0000-0002-2481-1612","observed_orcids":["https://orcid.org/0000-0002-2481-1612"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francis M\u00e9graud","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":21.7044,"has_fulltext":false,"cited_by_count":150,"citation_normalized_percentile":{"value":0.99680875,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"58","issue":"4","first_page":"304","last_page":"317"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori-infection","display_name":"Helicobacter pylori infection","score":0.9480000138282776},{"id":"https://openalex.org/keywords/h-pylori-prevalence","display_name":"H. pylori prevalence","score":0.7369999885559082},{"id":"https://openalex.org/keywords/acid-tolerance","display_name":"acid resistance","score":0.7609999775886536},{"id":"https://openalex.org/keywords/colonization-factors","display_name":"colonization factors","score":0.8650000095367432},{"id":"https://openalex.org/keywords/h-pylori-diagnosis","display_name":"H. pylori infection diagnosis","score":0.8270000219345093},{"id":"https://openalex.org/keywords/eradication-therapy","display_name":"eradication therapy","score":0.7889999747276306},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"antibiotic resistance","score":0.906000018119812},{"id":"https://openalex.org/keywords/clarithromycin","display_name":"clarithromycin","score":0.8740000128746033},{"id":"https://openalex.org/keywords/quadruple-therapy","display_name":"quadruple therapy","score":0.9800000190734863},{"id":"https://openalex.org/keywords/triple-therapy","display_name":"triple therapy","score":0.6740000247955322},{"id":"https://openalex.org/keywords/rifabutin","display_name":"rifabutin","score":0.8650000095367432},{"id":"https://openalex.org/keywords/furazolidone","display_name":"furazolidone","score":0.9810000061988831},{"id":"https://openalex.org/keywords/gastric-colonization","display_name":"gastric colonization","score":0.41999998688697815}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8728963732719421},{"id":"https://openalex.org/C2780867798","wikidata":"https://www.wikidata.org/wiki/Q1135705","display_name":"Rifabutin","level":4,"score":0.8084763288497925},{"id":"https://openalex.org/C2776962512","wikidata":"https://www.wikidata.org/wiki/Q118551","display_name":"Clarithromycin","level":3,"score":0.7873520255088806},{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.7845054864883423},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.663735568523407},{"id":"https://openalex.org/C2781276175","wikidata":"https://www.wikidata.org/wiki/Q424193","display_name":"Levofloxacin","level":3,"score":0.6283053755760193},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4854431748390198},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.4768342077732086},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.4713957607746124},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4228295087814331},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.42008861899375916},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3596753478050232},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.35713082551956177},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.15796148777008057},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.13305151462554932},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004415","descriptor_name":"Dyspepsia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010437","descriptor_name":"Peptic Ulcer","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018442","descriptor_name":"Lymphoma, B-Cell, Marginal Zone","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:27716738","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27716738","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Panminerva medica","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unito.it:2318/1620884","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2318/1620884","pdf_url":null,"source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2530367609","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27716738","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3188030220","https://openalex.org/W1504180115","https://openalex.org/W2413898130","https://openalex.org/W2969213072","https://openalex.org/W2052603050","https://openalex.org/W4378715144","https://openalex.org/W2973211234","https://openalex.org/W3149558419","https://openalex.org/W4302602398","https://openalex.org/W2152211277"],"abstract_inverted_index":{"The":[0,41],"discovery":[1],"that":[2,70,165],"the":[3,11,16,21,57,74,81,97,103,109,126,129,143,156,172,204,215],"bacterium":[4],"Helicobacter":[5],"pylori":[6,25,45,65,114,134],"(H.":[7],"pylori)":[8],"lives":[9],"in":[10,30,56,63,87,91],"stomach":[12],"has":[13],"rendered":[14],"out-of-date":[15],"concept":[17],"of":[18,20,35,43,59,73,80,106,112,128,147,174],"inhospitality":[19],"gastric":[22],"environment.":[23],"H.":[24,44,64,113,133],"is":[26,68,163],"able":[27],"to":[28,131],"survive":[29],"this":[31,95,192,202],"organ":[32],"through":[33],"mechanisms":[34],"acid":[36],"resistance":[37,180],"and":[38,53,121,181,219,227],"colonization":[39],"factors.":[40],"prevalence":[42],"infection":[46],"varies":[47],"depending":[48],"on":[49,102,108,119,142,155,171],"age,":[50],"socioeconomic":[51],"class,":[52],"country.":[54],"Currently,":[55],"context":[58],"a":[60,84,117,189,198],"decreased":[61],"trend":[62],"prevalence,":[66],"it":[67,162],"estimated":[69],"about":[71],"50%":[72],"world's":[75],"human":[76],"population":[77],"are":[78],"carriers":[79],"microorganism,":[82],"with":[83,116],"higher":[85],"rate":[86],"developing":[88],"countries":[89],"than":[90],"developed":[92],"countries.":[93],"In":[94,124,201],"review,":[96],"authors":[98],"provide":[99],"an":[100,152],"overview":[101],"current":[104],"status":[105],"knowledge":[107],"clinical":[110,157],"aspects":[111],"infection,":[115,135],"focus":[118],"diagnostic":[120],"therapeutic":[122],"challenges.":[123],"particular,":[125],"choice":[127],"test":[130,208],"diagnose":[132],"defined":[136],"as":[137,197],"invasive":[138],"or":[139,145,214],"non-invasive":[140],"based":[141],"need":[144],"not":[146],"biopsy":[148],"specimens":[149],"obtained":[150],"during":[151],"endoscopy,":[153],"depends":[154],"context.":[158],"Regarding":[159],"bacterial":[160],"eradication,":[161],"important":[164],"treatment":[166],"should":[167,194,223,230],"be":[168,195,224,231],"decided":[169],"locally":[170],"basis":[173],"local":[175],"antibiotic":[176,179],"usage,":[177],"documented":[178],"outcome":[182],"data.":[183],"For":[184],"patients":[185],"having":[186],"previously":[187],"received":[188],"clarithromycin-containing":[190],"regimen,":[191],"drug":[193],"avoided":[196],"second-line":[199],"therapy.":[200],"case,":[203],"tailored":[205],"therapy":[206,222],"(to":[207],"clarithromycin":[209],"susceptibility":[210],"before":[211],"prescribing":[212],"drugs)":[213],"so-called":[216],"quadruple":[217],"therapy,":[218],"triple":[220],"levofloxacin-based":[221],"proposed.":[225],"Rifabutin-":[226],"furazolidone-based":[228],"treatments":[229],"reserved":[232],"for":[233],"further":[234],"treatment.":[235]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":38},{"year":2018,"cited_by_count":25},{"year":2017,"cited_by_count":16}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-10-21T00:00:00"}