{"id":"https://openalex.org/W252964188","doi":null,"title":"Trends in age-specific cerebrovascular disease in the European Union.","display_name":"Trends in age-specific cerebrovascular disease in the European Union.","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W252964188","mag":"252964188","pmid":"https://pubmed.ncbi.nlm.nih.gov/25550927","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4276185"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:3243618","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4276185","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4276185","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100643071","display_name":"Hui Wang","orcid":"https://orcid.org/0000-0001-7452-3558","observed_orcids":["https://orcid.org/0000-0001-7452-3558"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Wang","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022198024","display_name":"Wei Yue Sun","orcid":"https://orcid.org/0000-0003-0833-0445","observed_orcids":["https://orcid.org/0000-0003-0833-0445"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Sun","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072388942","display_name":"Yue Ru Ji","orcid":"https://orcid.org/0000-0003-2464-8592","observed_orcids":["https://orcid.org/0000-0003-2464-8592"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Ji","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018562215","display_name":"Jing Shi","orcid":"https://orcid.org/0000-0002-9183-9631","observed_orcids":["https://orcid.org/0000-0002-9183-9631"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Shi","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113787917","display_name":"Qinkao Xuan","orcid":"https://orcid.org/0009-0004-3491-7041","observed_orcids":["https://orcid.org/0009-0004-3491-7041"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qinkao Xuan","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003672349","display_name":"Xiuzhi Wang","orcid":"https://orcid.org/0000-0002-3770-3231","observed_orcids":["https://orcid.org/0000-0002-3770-3231"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiuzhi Wang","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012318743","display_name":"Junjie Xiao","orcid":"https://orcid.org/0000-0002-9202-0003","observed_orcids":["https://orcid.org/0000-0002-9202-0003"]},"institutions":[{"id":"https://openalex.org/I113940042","display_name":"Shanghai University","ror":"https://ror.org/006teas31","country_code":"CN","type":"education","lineage":["https://openalex.org/I113940042"]},{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junjie Xiao","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China ; Regeneration Lab, School of Life Science, Shanghai University Shanghai 200444, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China ; Regeneration Lab, School of Life Science, Shanghai University Shanghai 200444, China","institution_ids":["https://openalex.org/I113940042","https://openalex.org/I4210152119","https://openalex.org/I83519826"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061752926","display_name":"Xiangqing Kong","orcid":"https://orcid.org/0000-0003-3309-1140","observed_orcids":["https://orcid.org/0000-0003-3309-1140"]},"institutions":[{"id":"https://openalex.org/I4210152119","display_name":"Jiangsu Province Hospital","ror":"https://ror.org/04py1g812","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210152119"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangqing Kong","raw_affiliation_strings":["Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China","institution_ids":["https://openalex.org/I4210152119"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"7","issue":"11","first_page":"4165","last_page":"73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12935","display_name":"Healthcare Systems and Public Health","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12935","display_name":"Healthcare Systems and Public Health","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.02070000022649765,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebrovascular-disease","display_name":"cerebrovascular disease","score":0.9089999794960022},{"id":"https://openalex.org/keywords/age-specific-mortality","display_name":"age-specific mortality","score":0.9300000071525574},{"id":"https://openalex.org/keywords/sex-differences-in-mortality","display_name":"sex differences in mortality","score":0.9210000038146973},{"id":"https://openalex.org/keywords/eu-member-states","display_name":"EU member states","score":0.7139999866485596},{"id":"https://openalex.org/keywords/mortality-decline","display_name":"mortality decline","score":0.49900001287460327},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.7649999856948853},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.5770000219345093},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9380000233650208},{"id":"https://openalex.org/keywords/cardiovascular-disease-prevention","display_name":"cardiovascular disease prevention","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7970781326293945},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.6635597348213196},{"id":"https://openalex.org/C2910001868","wikidata":"https://www.wikidata.org/wiki/Q458","display_name":"European union","level":2,"score":0.6431555151939392},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.6337215304374695},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5311272144317627},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5006747245788574},{"id":"https://openalex.org/C3017966228","wikidata":"https://www.wikidata.org/wiki/Q1067887","display_name":"European population","level":3,"score":0.4810333847999573},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.44215139746665955},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4379676282405853},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.28978431224823},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.10201945900917053},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09590873122215271},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C105639569","wikidata":"https://www.wikidata.org/wiki/Q582577","display_name":"Economic policy","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:3243618","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4276185","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:25550927","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25550927","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of clinical and experimental medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4276185","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4276185/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Clin Exp Med","raw_type":"Text"},{"id":"mag:252964188","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25550927","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3243618","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4276185","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1877835373","https://openalex.org/W1975640742","https://openalex.org/W2003147336","https://openalex.org/W2019401321","https://openalex.org/W2055821009","https://openalex.org/W2056029555","https://openalex.org/W2083353034","https://openalex.org/W2099462028","https://openalex.org/W2113465290","https://openalex.org/W2130189158","https://openalex.org/W2155121555","https://openalex.org/W2155477484","https://openalex.org/W2156549209","https://openalex.org/W2157622195","https://openalex.org/W2158569927","https://openalex.org/W2160280522"],"related_works":["https://openalex.org/W2055821009","https://openalex.org/W2144633993","https://openalex.org/W2156549209","https://openalex.org/W2047701934","https://openalex.org/W1974540266","https://openalex.org/W7096944002","https://openalex.org/W3108359442","https://openalex.org/W2310381004","https://openalex.org/W2442552566","https://openalex.org/W2134900650"],"abstract_inverted_index":{"Although":[0],"the":[1,12,19,36,46,57,66,88,153,164,173,212],"mortality":[2,41,50,61,77,90,106,119,133,169,197],"of":[3,22,38,51,176,214],"cerebrovascular":[4],"disease":[5],"(CVD)":[6],"has":[7],"been":[8],"steadily":[9],"declined":[10,159],"in":[11,24,48,59,62,105,122,145,172,183,194],"European":[13,39],"Union":[14],"(EU),":[15],"CVD":[16,40,49,60,118,161,168,184,196,215],"remains":[17,42],"among":[18],"major":[20],"causes":[21],"death":[23],"EU.":[25,177],"As":[26],"risk":[27,216],"factors":[28],"such":[29],"asobesity":[30],"and":[31,72,75,81,101,116,125],"diabetes":[32],"mellitus":[33],"are":[34],"increasing,":[35],"trends":[37,58,104,134],"unknown.":[43],"To":[44],"understand":[45],"variation":[47],"different":[52,149,200],"EU":[53,63,138,154,204],"countries,":[54],"we":[55],"studied":[56],"countries":[64],"over":[65,108],"last":[67,165],"three":[68,166],"decades":[69],"between":[70,79,114,137],"males":[71],"females.":[73],"Age-":[74],"sex-specific":[76],"rates":[78,107,198],"1980":[80,115],"2011":[82],"were":[83,188],"calculated":[84],"by":[85],"data":[86],"from":[87],"WHO":[89],"database.":[91],"Joinpoint":[92],"software":[93],"was":[94,143],"used":[95],"to":[96,102,206],"calculate":[97],"annual":[98],"percentage":[99],"changes":[100],"characterize":[103],"time.":[109],"Our":[110],"study":[111],"showed":[112],"that":[113],"2011,":[117],"significantly":[120],"decreased":[121,170],"both":[123],"men":[124],"women":[126],"across":[127],"all":[128],"age":[129,150],"groups.":[130],"The":[131,140,202],"specific":[132],"varied":[135],"largely":[136],"countries.":[139],"plateau":[141],"trend":[142,160],"observed":[144],"little":[146],"regions":[147],"at":[148,199],"groups,":[151],"however,":[152],"as":[155,190],"a":[156],"whole":[157,203],"displayed":[158],"mortality.":[162],"During":[163],"decades,":[167],"substantially":[171],"entire":[174],"population":[175],"However,":[178],"despite":[179],"this":[180],"overall":[181],"decline":[182],"mortality,":[185],"several":[186],"areas":[187],"identified":[189],"having":[191],"no":[192],"change":[193],"their":[195],"period.":[201],"needs":[205],"establish":[207],"strict":[208],"prevention":[209],"measures":[210],"toreduce":[211],"incidence":[213],"factors.":[217]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}