{"id":"https://openalex.org/W2526003261","doi":"https://doi.org/10.1016/s0022-5223(19)34915-3","title":"Evidence for the role of neutrophils in reperfusion injury after cold cardioplegic ischemia in neonatal lambs","display_name":"Evidence for the role of neutrophils in reperfusion injury after cold cardioplegic ischemia in neonatal lambs","publication_year":1992,"publication_date":"1992-05-01","ids":{"openalex":"https://openalex.org/W2526003261","doi":"https://doi.org/10.1016/s0022-5223(19)34915-3","mag":"2526003261","pmid":"https://pubmed.ncbi.nlm.nih.gov/1569774"},"language":"en","primary_location":{"id":"doi:10.1016/s0022-5223(19)34915-3","doi":"https://doi.org/10.1016/s0022-5223(19)34915-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0022-5223(19)34915-3","pdf_url":null,"source":{"id":"https://openalex.org/S127437062","display_name":"Journal of Thoracic and Cardiovascular Surgery","issn_l":"0022-5223","issn":["0022-5223","1085-8687","1097-685X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Thoracic and Cardiovascular Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0022-5223(19)34915-3","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Hiroaki Kawata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hiroaki Kawata","raw_affiliation_strings":["Department of Cardiovascular Surgery, Children's Hospital, Boston, Mass. 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Children's Hospital, Boston, Mass. 02115","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006612197","display_name":"Kazuo Sawatari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kazuo Sawatari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5023064529","display_name":"John Eleanor Mayer","orcid":"https://orcid.org/0000-0002-5849-2971","observed_orcids":["https://orcid.org/0000-0002-5849-2971"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John E. Mayer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":4.5506,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.95114641,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"103","issue":"5","first_page":"908","last_page":"918"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9101999998092651,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9101999998092651,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.05689999833703041,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.020999999716877937,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.9279999732971191},{"id":"https://openalex.org/keywords/neutrophil-depletion","display_name":"neutrophil depletion","score":0.7940000295639038},{"id":"https://openalex.org/keywords/platelet-activating-factor-antagonist","display_name":"platelet-activating factor antagonist","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cv-3988","display_name":"CV-3988","score":0.9869999885559082},{"id":"https://openalex.org/keywords/neutrophil-endothelial-interaction","display_name":"neutrophil-endothelial interaction","score":0.9480000138282776},{"id":"https://openalex.org/keywords/endothelial-function","display_name":"endothelial function","score":0.8640000224113464},{"id":"https://openalex.org/keywords/coronary-vascular-resistance","display_name":"coronary vascular resistance","score":0.8769999742507935},{"id":"https://openalex.org/keywords/coronary-blood-flow","display_name":"coronary blood flow","score":0.7369999885559082},{"id":"https://openalex.org/keywords/blood-perfused-heart","display_name":"blood-perfused heart","score":0.656000018119812},{"id":"https://openalex.org/keywords/cardiac-recovery","display_name":"cardiac function recovery","score":0.574999988079071},{"id":"https://openalex.org/keywords/acetylcholine-response","display_name":"acetylcholine response","score":0.75},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.6809999942779541},{"id":"https://openalex.org/keywords/cardioprotection","display_name":"cardioprotection","score":0.6299999952316284},{"id":"https://openalex.org/keywords/neutrophil-adhesion","display_name":"neutrophil adhesion","score":0.34700000286102295},{"id":"https://openalex.org/keywords/leukocyte-adhesion","display_name":"leukocyte adhesion","score":0.47699999809265137},{"id":"https://openalex.org/keywords/leukocyte-endothelial-interaction","display_name":"leukocyte-endothelium interaction","score":0.4690000116825104},{"id":"https://openalex.org/keywords/platelet-leukocyte-interaction","display_name":"platelet-leukocyte interaction","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8646515607833862},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.6053284406661987},{"id":"https://openalex.org/C58245268","wikidata":"https://www.wikidata.org/wiki/Q456026","display_name":"Vascular resistance","level":3,"score":0.5169802904129028},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5151818990707397},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.4768087565898895},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4380185604095459},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4236191511154175},{"id":"https://openalex.org/C2779610285","wikidata":"https://www.wikidata.org/wiki/Q27108300","display_name":"Sodium nitroprusside","level":3,"score":0.4195474088191986},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.3950466513633728},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.1451687216758728}],"mesh":[{"descriptor_ui":"D000109","descriptor_name":"Acetylcholine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002314","descriptor_name":"Cardioplegic Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006324","descriptor_name":"Heart Arrest, Induced","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010742","descriptor_name":"Phospholipid Ethers","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010972","descriptor_name":"Platelet Activating Factor","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014655","descriptor_name":"Vascular Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D015428","descriptor_name":"Myocardial Reperfusion Injury","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D015428","descriptor_name":"Myocardial Reperfusion Injury","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0022-5223(19)34915-3","doi":"https://doi.org/10.1016/s0022-5223(19)34915-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0022-5223(19)34915-3","pdf_url":null,"source":{"id":"https://openalex.org/S127437062","display_name":"Journal of Thoracic and Cardiovascular Surgery","issn_l":"0022-5223","issn":["0022-5223","1085-8687","1097-685X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Thoracic and Cardiovascular Surgery","raw_type":"journal-article"},{"id":"pmid:1569774","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1569774","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of thoracic and cardiovascular surgery","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0022-5223(19)34915-3","doi":"https://doi.org/10.1016/s0022-5223(19)34915-3","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0022-5223(19)34915-3","pdf_url":null,"source":{"id":"https://openalex.org/S127437062","display_name":"Journal of Thoracic and Cardiovascular Surgery","issn_l":"0022-5223","issn":["0022-5223","1085-8687","1097-685X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Thoracic and Cardiovascular Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W64761778","https://openalex.org/W179793388","https://openalex.org/W1515846068","https://openalex.org/W1525482898","https://openalex.org/W1592252967","https://openalex.org/W1753169826","https://openalex.org/W1890393137","https://openalex.org/W1977784192","https://openalex.org/W1982363639","https://openalex.org/W1991189640","https://openalex.org/W2011513090","https://openalex.org/W2015312259","https://openalex.org/W2029578894","https://openalex.org/W2033423580","https://openalex.org/W2034972830","https://openalex.org/W2038537849","https://openalex.org/W2065696528","https://openalex.org/W2072334979","https://openalex.org/W2076610820","https://openalex.org/W2079790969","https://openalex.org/W2097744068","https://openalex.org/W2120768528","https://openalex.org/W2140233303","https://openalex.org/W2141211759","https://openalex.org/W2151067784","https://openalex.org/W2159822998","https://openalex.org/W2162602750","https://openalex.org/W2167276387","https://openalex.org/W2176682934","https://openalex.org/W2183353764","https://openalex.org/W2287593190","https://openalex.org/W2288475636","https://openalex.org/W2313270086","https://openalex.org/W2395969380","https://openalex.org/W2396166791","https://openalex.org/W2417809832","https://openalex.org/W2418406093","https://openalex.org/W2418439268","https://openalex.org/W2419508721","https://openalex.org/W2422528039","https://openalex.org/W2423511373","https://openalex.org/W2615721862","https://openalex.org/W4249748026","https://openalex.org/W4323237485"],"related_works":["https://openalex.org/W2409234623","https://openalex.org/W1221093695","https://openalex.org/W2001127036","https://openalex.org/W2410464153","https://openalex.org/W2029433148","https://openalex.org/W2014515869","https://openalex.org/W1965742628","https://openalex.org/W2212900605","https://openalex.org/W2015096657","https://openalex.org/W1964766681"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-10-07T00:00:00"}