{"id":"https://openalex.org/W2525731446","doi":"https://doi.org/10.1186/s13550-016-0226-3","title":"Test-retest analysis of a non-invasive method of quantifying [11C]-PBR28 binding in Alzheimer\u2019s disease","display_name":"Test-retest analysis of a non-invasive method of quantifying [11C]-PBR28 binding in Alzheimer\u2019s disease","publication_year":2016,"publication_date":"2016-09-27","ids":{"openalex":"https://openalex.org/W2525731446","doi":"https://doi.org/10.1186/s13550-016-0226-3","mag":"2525731446","pmid":"https://pubmed.ncbi.nlm.nih.gov/27678494","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5039146"},"language":"en","primary_location":{"id":"doi:10.1186/s13550-016-0226-3","doi":"https://doi.org/10.1186/s13550-016-0226-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13550-016-0226-3","pdf_url":"https://ejnmmires.springeropen.com/track/pdf/10.1186/s13550-016-0226-3","source":{"id":"https://openalex.org/S2764570898","display_name":"EJNMMI Research","issn_l":"2191-219X","issn":["2191-219X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EJNMMI Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ejnmmires.springeropen.com/track/pdf/10.1186/s13550-016-0226-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109201993","display_name":"Akshay Nair","orcid":"https://orcid.org/0000-0002-7872-977X","observed_orcids":["https://orcid.org/0000-0002-7872-977X"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Akshay Nair","raw_affiliation_strings":["UCL Huntington's Disease Research Group, 2nd floor, Russell Square House, 10-12 Russell Square, London, WC1B 5EH, UK. akshay.nair@ucl.ac.uk","UCL Huntington's Disease Research Group, 2nd floor, Russell Square House, 10-12 Russell Square, London, WC1B 5EH, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL Huntington's Disease Research Group, 2nd floor, Russell Square House, 10-12 Russell Square, London, WC1B 5EH, UK. akshay.nair@ucl.ac.uk","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"UCL Huntington's Disease Research Group, 2nd floor, Russell Square House, 10-12 Russell Square, London, WC1B 5EH, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029739167","display_name":"Mattia Veronese","orcid":"https://orcid.org/0000-0003-3562-0683","observed_orcids":["https://orcid.org/0000-0003-3562-0683"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mattia Veronese","raw_affiliation_strings":["Centre for Neuroimaging Sciences, IoPPN, King's College London, Box PO89, De Crespigny Park, London, SE5 8AF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuroimaging Sciences, IoPPN, King's College London, Box PO89, De Crespigny Park, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101413298","display_name":"Xiaohui Xu","orcid":"https://orcid.org/0000-0003-0205-0653","observed_orcids":["https://orcid.org/0000-0003-0205-0653"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210115181","display_name":"Maudsley Hospital","ror":"https://ror.org/02788t795","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200323923","https://openalex.org/I4210115181"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Xiaohui Xu","raw_affiliation_strings":["MRC Social, Genetic and Developmental Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, De Crespigny Park, Denmark Hill, London, SE5 8EF, UK","NIHR Biomedical Research Centre for Mental Health, Maudsley Hospital and Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Social, Genetic and Developmental Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, De Crespigny Park, Denmark Hill, London, SE5 8EF, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"NIHR Biomedical Research Centre for Mental Health, Maudsley Hospital and Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I4210115181"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041668398","display_name":"Charles J. C. Curtis","orcid":"https://orcid.org/0000-0002-2992-1941","observed_orcids":["https://orcid.org/0000-0002-2992-1941"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210115181","display_name":"Maudsley Hospital","ror":"https://ror.org/02788t795","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200323923","https://openalex.org/I4210115181"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Charles Curtis","raw_affiliation_strings":["MRC Social, Genetic and Developmental Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, De Crespigny Park, Denmark Hill, London, SE5 8EF, UK","NIHR Biomedical Research Centre for Mental Health, Maudsley Hospital and Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Social, Genetic and Developmental Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, De Crespigny Park, Denmark Hill, London, SE5 8EF, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"NIHR Biomedical Research Centre for Mental Health, Maudsley Hospital and Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I4210115181"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079810332","display_name":"Federico Turkheimer","orcid":"https://orcid.org/0000-0002-3766-3815","observed_orcids":["https://orcid.org/0000-0002-3766-3815"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Federico Turkheimer","raw_affiliation_strings":["Centre for Neuroimaging Sciences, IoPPN, King's College London, Box PO89, De Crespigny Park, London, SE5 8AF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuroimaging Sciences, IoPPN, King's College London, Box PO89, De Crespigny Park, London, SE5 8AF, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043071365","display_name":"Robert J. Howard","orcid":"https://orcid.org/0000-0002-3071-2338","observed_orcids":["https://orcid.org/0000-0002-3071-2338","https://orcid.org/0000-0003-2349-0287"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Howard","raw_affiliation_strings":["Division of Psychiatry, University College London, 6th Floor, Wings A and B, Maple House, 149 Tottenham Court Road, London, W1T 7NF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Psychiatry, University College London, 6th Floor, Wings A and B, Maple House, 149 Tottenham Court Road, London, W1T 7NF, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035979012","display_name":"Suzanne Reeves","orcid":"https://orcid.org/0000-0001-8053-7024","observed_orcids":["https://orcid.org/0000-0001-8053-7024"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Suzanne Reeves","raw_affiliation_strings":["Division of Psychiatry, University College London, 6th Floor, Wings A and B, Maple House, 149 Tottenham Court Road, London, W1T 7NF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Psychiatry, University College London, 6th Floor, Wings A and B, Maple House, 149 Tottenham Court Road, London, W1T 7NF, UK","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5109201993"],"corresponding_institution_ids":["https://openalex.org/I45129253"],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":{"value":1435,"currency":"EUR","value_usd":1547},"fwci":3.6791,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.9343751,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"6","issue":"1","first_page":"14","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5062999725341797,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5062999725341797,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.25850000977516174,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.14030000567436218,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/11c-pbr28","display_name":"[11C]PBR28","score":0.906000018119812},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.875},{"id":"https://openalex.org/keywords/test-retest-reliability","display_name":"test-retest reliability","score":0.9139999747276306},{"id":"https://openalex.org/keywords/translocator-protein-tspo","display_name":"translocator protein (TSPO)","score":0.8659999966621399},{"id":"https://openalex.org/keywords/standardized-uptake-value","display_name":"standardized uptake value","score":0.8809999823570251},{"id":"https://openalex.org/keywords/noninvasive-measurement","display_name":"non-invasive measurement","score":0.6600000262260437},{"id":"https://openalex.org/keywords/amyloid-imaging","display_name":"amyloid imaging","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8801818490028381},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.5212857723236084},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5198579430580139},{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.45558980107307434},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38638126850128174},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3409234881401062},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":11,"locations":[{"id":"doi:10.1186/s13550-016-0226-3","doi":"https://doi.org/10.1186/s13550-016-0226-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13550-016-0226-3","pdf_url":"https://ejnmmires.springeropen.com/track/pdf/10.1186/s13550-016-0226-3","source":{"id":"https://openalex.org/S2764570898","display_name":"EJNMMI Research","issn_l":"2191-219X","issn":["2191-219X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EJNMMI Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5039146","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5039146","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EJNMMI Res","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5309185","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5309185","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EJNMMI Res","raw_type":"Text"},{"id":"pmid:27678494","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27678494","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EJNMMI research","raw_type":"Journal Article"},{"id":"pmid:28197899","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28197899","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EJNMMI research","raw_type":"Published Erratum"},{"id":"pmh:oai:kclpure.kcl.ac.uk:openaire/7d1140a4-025d-469d-8d73-655e1fef993c","doi":null,"is_oa":true,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/7d1140a4-025d-469d-8d73-655e1fef993c","pdf_url":"https://kclpure.kcl.ac.uk/ws/files/57942739/art_3A10.1186_2Fs13550_016_0226_3.pdf","source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nair, A, Veronese, M, Xu, X, Curtis, C, Turkheimer, F, Howard, R & Reeves, S 2016, 'Test-retest analysis of a non-invasive method of quantifying [(11)C]-PBR28 binding in Alzheimer's disease', EJNMMI Research, vol. 6, no. 1, pp. 72. https://doi.org/10.1186/s13550-016-0226-3","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1520668","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1520668/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"EJNMMI Research , 6 (UNSP 72) (2016)","raw_type":"Article"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/41723","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/41723","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:www.research.unipd.it:11577/3411437","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11577/3411437","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:www.research.unipd.it:11577/3461360","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11577/3461360","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2618237073","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1520668/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1186/s13550-016-0226-3","doi":"https://doi.org/10.1186/s13550-016-0226-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13550-016-0226-3","pdf_url":"https://ejnmmires.springeropen.com/track/pdf/10.1186/s13550-016-0226-3","source":{"id":"https://openalex.org/S2764570898","display_name":"EJNMMI Research","issn_l":"2191-219X","issn":["2191-219X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EJNMMI Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3768069617","display_name":null,"funder_award_id":"ACF-2011-17-005","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G6367850701","display_name":"Rationalisation of antipsychotic drug use in older people, using [18F]-Fallypride PET","funder_award_id":"NIHR/CS/010/019","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G7409732208","display_name":"PET Methodology","funder_award_id":"G1100809/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320311198","display_name":"South London and Maudsley NHS Foundation Trust","ror":"https://ror.org/015803449"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320285","display_name":"King's College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320325311","display_name":"University College London Hospitals NHS Foundation Trust","ror":"https://ror.org/042fqyp44"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2525731446.pdf","grobid_xml":"https://content.openalex.org/works/W2525731446.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1779785652","https://openalex.org/W1969387798","https://openalex.org/W1986611577","https://openalex.org/W1996242543","https://openalex.org/W2012037984","https://openalex.org/W2045347306","https://openalex.org/W2077541192","https://openalex.org/W2086522859","https://openalex.org/W2099151445","https://openalex.org/W2113405339","https://openalex.org/W2115017507","https://openalex.org/W2121010289","https://openalex.org/W2128584554","https://openalex.org/W2160879352","https://openalex.org/W2285480544","https://openalex.org/W2315497305","https://openalex.org/W2358666620"],"related_works":["https://openalex.org/W2618237073","https://openalex.org/W2339137091","https://openalex.org/W2099151445","https://openalex.org/W2131359357","https://openalex.org/W6903564209","https://openalex.org/W2293941712","https://openalex.org/W2124799635","https://openalex.org/W4206136919","https://openalex.org/W2897066629","https://openalex.org/W4206493567"],"abstract_inverted_index":{"PURPOSE:":[0],"In":[1,80,228],"order":[2],"to":[3,25,51,129,137],"maximise":[4],"the":[5,62,83,105,124,153,157,163,210],"utility":[6],"of":[7,29,65,86,123,148,237,254,257,262,265,269,278],"[(11)C]-PBR28":[8,112,238,270],"for":[9,75],"use":[10],"in":[11,17,53,68,92,142,275],"longitudinal":[12,276],"studies":[13,251,277],"and":[14,104,134,145,156,180,221],"clinical":[15,76],"trials":[16,77],"Alzheimer's":[18],"disease":[19],"(AD),":[20],"there":[21],"is":[22,78],"a":[23,71],"need":[24],"develop":[26],"non-invasive":[27],"metrics":[28,89,236],"tracer":[30],"binding":[31,107,239],"that":[32,42,234],"do":[33],"not":[34],"require":[35],"arterial":[36],"cannulation.":[37],"Recent":[38],"work":[39],"has":[40],"suggested":[41],"standardised":[43],"uptake":[44],"value":[45],"(SUV)-based":[46],"methods":[47,268],"may":[48,272],"be":[49],"sensitive":[50],"changes":[52],"translocator":[54],"protein":[55],"(TSPO)":[56],"levels":[57],"associated":[58],"with":[59,101,192,250],"neurodegeneration.":[60],"However,":[61],"test-retest":[63,84,120],"reliability":[64,85,121,182,194,223],"these":[66],"approaches":[67],"AD":[69,93,103,230],"over":[70,95,243],"time":[72],"period":[73],"relevant":[74],"unknown.":[79],"this":[81,229],"study,":[82],"three":[87,164],"SUV-based":[88,263],"was":[90,150],"assessed":[91,151],"patients":[94,100],"12":[96,116,244],"weeks.":[97,245],"METHODS:":[98],"Five":[99],"mild":[102],"high-affinity":[106],"TSPO":[108],"genotype":[109],"underwent":[110],"two":[111],"PET":[113],"scans":[114],"approximately":[115],"weeks":[117],"apart.":[118],"The":[119],"(TRR)":[122],"unadjusted":[125],"SUV,":[126],"SUV":[127,135,188],"relative":[128],"cerebellar":[130],"grey":[131],"matter":[132],"(SUVRC)":[133],"normalised":[136],"whole":[138],"brain":[139],"activity":[140],"(SUVRWB)":[141],"nine":[143],"cortical":[144],"limbic":[146],"regions":[147],"interest":[149],"using":[152],"absolute":[154,172,255],"variability":[155,173,201,214],"intraclass":[158],"correlation":[159],"coefficient.":[160],"RESULTS:":[161],"Of":[162],"measures,":[165],"SUVRWB":[166],"performed":[167,190],"best":[168],"overall,":[169],"showing":[170],"low":[171,222],"(mean":[174,183,202,215],"-0.13":[175],"%,":[176,204,217],"SD":[177,205,218],"2.47":[178],"%)":[179,220],"high":[181,193,200,241],"ICC":[184],"=":[185,196,225],"0.83).":[186],"Unadjusted":[187],"also":[189,199],"well,":[191],"(ICC":[195,224],"0.94)":[197],"but":[198],"-1.24":[203],"7.28":[206],"%).":[207],"By":[208],"comparison,":[209],"SUVRC":[211],"showed":[212,240],"higher":[213],"-3.98":[216],"7.07":[219],"0.65).":[226],"CONCLUSIONS:":[227],"sample,":[231],"we":[232],"found":[233],"SUV-derived":[235],"stability":[242],"These":[246],"results":[247],"compare":[248],"favourably":[249],"reporting":[252],"TRR":[253],"quantification":[256],"[(11)C]-PBR28.":[258],"Pending":[259],"further":[260],"validation":[261],"measures":[264],"[(11)C]-PBR28,":[266],"semi-quantitative":[267],"analysis":[271],"prove":[273],"useful":[274],"AD.":[279]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-10-07T00:00:00"}
