{"id":"https://openalex.org/W2525574906","doi":null,"title":"ApoE is an important mediator of LRP1 functions in the lipid metabolism, glucose homeostasis and adipogenesis","display_name":"ApoE is an important mediator of LRP1 functions in the lipid metabolism, glucose homeostasis and adipogenesis","publication_year":2009,"publication_date":"2009-09-01","ids":{"openalex":"https://openalex.org/W2525574906","mag":"2525574906"},"language":"en","primary_location":{"id":"mag:2525574906","doi":null,"is_oa":false,"landing_page_url":"https://lirias.kuleuven.be/handle/123456789/256246","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038608536","display_name":"Philip L.S.M. Gordts","orcid":"https://orcid.org/0000-0001-7224-4328","observed_orcids":["https://orcid.org/0000-0001-7224-4328"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Philip L.S.M. Gordts","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7224-4328","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007880923","display_name":"Alexander Bartelt","orcid":"https://orcid.org/0000-0001-7840-3991","observed_orcids":["https://orcid.org/0000-0001-7840-3991"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander Bartelt","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7840-3991","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005653232","display_name":"J\u00f6erg Heeren","orcid":"https://orcid.org/0000-0002-5647-1034","observed_orcids":["https://orcid.org/0000-0002-5647-1034"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J\u00f6erg Heeren","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5647-1034","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5066480034","display_name":"Anton Roebroek","orcid":"https://orcid.org/0000-0002-9111-5836","observed_orcids":["https://orcid.org/0000-0002-9111-5836"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anton Roebroek","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9111-5836","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.307721,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.5029000043869019,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.5029000043869019,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.2215999960899353,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.06669999659061432,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apolipoprotein-e","display_name":"apolipoprotein E","score":0.9620000123977661},{"id":"https://openalex.org/keywords/lrp1","display_name":"LRP1","score":0.9789999723434448},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.9760000109672546},{"id":"https://openalex.org/keywords/glucose-homeostasis","display_name":"glucose homeostasis","score":1.0},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.7940000295639038},{"id":"https://openalex.org/keywords/lipoprotein-clearance","display_name":"lipoprotein clearance","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.8215471506118774},{"id":"https://openalex.org/C2107291","wikidata":"https://www.wikidata.org/wiki/Q14886885","display_name":"Mediator","level":2,"score":0.7432066202163696},{"id":"https://openalex.org/C3018667095","wikidata":"https://www.wikidata.org/wiki/Q3455903","display_name":"Glucose homeostasis","level":4,"score":0.6480640172958374},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.5791419744491577},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.44556725025177},{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.43257269263267517},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4299365282058716},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42887333035469055},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3808642029762268},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.34430521726608276},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3164198100566864},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.30765247344970703},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3038488030433655},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.23332521319389343},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.17780500650405884},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1634901762008667},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2525574906","doi":null,"is_oa":false,"landing_page_url":"https://lirias.kuleuven.be/handle/123456789/256246","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2520704994","https://openalex.org/W2068693033","https://openalex.org/W7095883637","https://openalex.org/W4399172332","https://openalex.org/W2069307901","https://openalex.org/W1607585198","https://openalex.org/W7095179408","https://openalex.org/W4386257102","https://openalex.org/W2077249332","https://openalex.org/W2606677245"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-10-07T00:00:00"}