{"id":"https://openalex.org/W2524661237","doi":"https://doi.org/10.1249/00005768-200605001-03062","title":"The Effects of Nightly Normobaric Hypoxia on Running Economy and Hemoglobin Mass","display_name":"The Effects of Nightly Normobaric Hypoxia on Running Economy and Hemoglobin Mass","publication_year":2006,"publication_date":"2006-05-01","ids":{"openalex":"https://openalex.org/W2524661237","doi":"https://doi.org/10.1249/00005768-200605001-03062","mag":"2524661237"},"language":"en","primary_location":{"id":"doi:10.1249/00005768-200605001-03062","doi":"https://doi.org/10.1249/00005768-200605001-03062","is_oa":false,"landing_page_url":"https://doi.org/10.1249/00005768-200605001-03062","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071191402","display_name":"Mitsuo Neya","orcid":"https://orcid.org/0000-0002-2892-5262","observed_orcids":["https://orcid.org/0000-0002-2892-5262"]},"institutions":[{"id":"https://openalex.org/I4405287692","display_name":"Japan Institute of Sports Sciences","ror":"https://ror.org/05xemht68","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210109266","https://openalex.org/I4405287692"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuo Neya","raw_affiliation_strings":["1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","2Japan Institute of Sports Sciences, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"2Japan Institute of Sports Sciences, Tokyo, Japan","institution_ids":["https://openalex.org/I4405287692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011201733","display_name":"Taketeru Maegawa","orcid":"https://orcid.org/0000-0003-2312-9889","observed_orcids":["https://orcid.org/0000-0003-2312-9889"]},"institutions":[{"id":"https://openalex.org/I4405287692","display_name":"Japan Institute of Sports Sciences","ror":"https://ror.org/05xemht68","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210109266","https://openalex.org/I4405287692"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taketeru Maegawa","raw_affiliation_strings":["1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","2Japan Institute of Sports Sciences, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"2Japan Institute of Sports Sciences, Tokyo, Japan","institution_ids":["https://openalex.org/I4405287692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012749308","display_name":"Yasuko Kumai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287692","display_name":"Japan Institute of Sports Sciences","ror":"https://ror.org/05xemht68","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210109266","https://openalex.org/I4405287692"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuko Kumai","raw_affiliation_strings":["1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","2Japan Institute of Sports Sciences, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"2Japan Institute of Sports Sciences, Tokyo, Japan","institution_ids":["https://openalex.org/I4405287692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006605745","display_name":"Taisuke Enoki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287692","display_name":"Japan Institute of Sports Sciences","ror":"https://ror.org/05xemht68","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210109266","https://openalex.org/I4405287692"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taisuke Enoki","raw_affiliation_strings":["1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","2Japan Institute of Sports Sciences, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"2Japan Institute of Sports Sciences, Tokyo, Japan","institution_ids":["https://openalex.org/I4405287692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011955308","display_name":"Takashi Kawahara","orcid":"https://orcid.org/0000-0002-7049-3379","observed_orcids":["https://orcid.org/0000-0002-7049-3379"]},"institutions":[{"id":"https://openalex.org/I4405287692","display_name":"Japan Institute of Sports Sciences","ror":"https://ror.org/05xemht68","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210109266","https://openalex.org/I4405287692"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Kawahara","raw_affiliation_strings":["1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","2Japan Institute of Sports Sciences, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"2Japan Institute of Sports Sciences, Tokyo, Japan","institution_ids":["https://openalex.org/I4405287692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113495471","display_name":"Christopher J. Gore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405287692","display_name":"Japan Institute of Sports Sciences","ror":"https://ror.org/05xemht68","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210109266","https://openalex.org/I4405287692"]},{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Christopher J. Gore","raw_affiliation_strings":["1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","2Japan Institute of Sports Sciences, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Dept. of Arts and Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]},{"raw_affiliation_string":"2Japan Institute of Sports Sciences, Tokyo, Japan","institution_ids":["https://openalex.org/I4405287692"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":"Supplement","first_page":"S524","last_page":"S524"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10157","display_name":"Sports Performance and Training","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/normobaric-hypoxia","display_name":"normobaric hypoxia","score":0.7850000262260437},{"id":"https://openalex.org/keywords/intermittent-hypoxia","display_name":"intermittent hypoxia","score":0.9309999942779541},{"id":"https://openalex.org/keywords/hemoglobin-mass","display_name":"hemoglobin mass","score":0.7250000238418579},{"id":"https://openalex.org/keywords/running-economy","display_name":"running economy","score":0.9679999947547913},{"id":"https://openalex.org/keywords/vo2max","display_name":"VO2max","score":0.8230000138282776},{"id":"https://openalex.org/keywords/altitude-training","display_name":"altitude training","score":0.6200000047683716},{"id":"https://openalex.org/keywords/erythropoiesis","display_name":"erythropoiesis","score":0.7049999833106995},{"id":"https://openalex.org/keywords/endurance-runners","display_name":"endurance runners","score":0.6179999709129333},{"id":"https://openalex.org/keywords/blood-lactate","display_name":"blood lactate","score":0.8140000104904175},{"id":"https://openalex.org/keywords/ventilation","display_name":"ventilation","score":0.6169999837875366},{"id":"https://openalex.org/keywords/carbon-monoxide-rebreathing","display_name":"carbon monoxide rebreathing","score":0.6309999823570251},{"id":"https://openalex.org/keywords/oxygen-uptake-kinetics","display_name":"oxygen uptake kinetics","score":0.31200000643730164}],"concepts":[{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.6502519249916077},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.6053204536437988},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.5076507329940796},{"id":"https://openalex.org/C2781464450","wikidata":"https://www.wikidata.org/wiki/Q839144","display_name":"Treadmill","level":2,"score":0.45650985836982727},{"id":"https://openalex.org/C196310339","wikidata":"https://www.wikidata.org/wiki/Q60354","display_name":"VO2 max","level":4,"score":0.4439021944999695},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.3979146480560303},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34586071968078613},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.300085186958313},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.21821463108062744},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.19226166605949402},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17697212100028992},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.17629197239875793},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14655721187591553},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1249/00005768-200605001-03062","doi":"https://doi.org/10.1249/00005768-200605001-03062","is_oa":false,"landing_page_url":"https://doi.org/10.1249/00005768-200605001-03062","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1976775735","https://openalex.org/W1432469196","https://openalex.org/W2119852978","https://openalex.org/W2075090027","https://openalex.org/W2156319434","https://openalex.org/W2109368394","https://openalex.org/W4387062003","https://openalex.org/W2045008239","https://openalex.org/W2019823222","https://openalex.org/W2219913752"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"investigate":[2],"the":[3,10,106,112,116,223,289,305,322],"effects":[4],"of":[5,160,209,299],"nightly":[6],"intermittent":[7,210],"hypoxia":[8,213,333],"on":[9,130],"total":[11],"hemoglobin":[12],"mass":[13],"(THb)":[14],"maximum":[15],"oxygen":[16],"consumption":[17],"(VO2max)":[18],"and":[19,26,54,66,80,91,93,98,118,138,248,264,271,279,320],"running":[20,125,327],"economy.":[21],"METHODS:":[22],"Sixteen":[23],"college-level":[24],"long-":[25],"middle-distance":[27],"runners":[28],"(mean":[29],"\u00b1":[30],"SD":[31],"age,":[32],"height,":[33],"mass,":[34],"VO2max":[35,190],"=":[36,62],"22\u00b12":[37],"yr,":[38],"169\u00b15":[39],"cm,58.4\u00b16.0":[40],"kg,":[41],"60.1\u00b17.5":[42],"ml/kg/min)":[43],"were":[44,95,238,302],"assigned":[45],"to":[46,72,154,212,307],"a":[47,73,131,186,227],"hypoxic":[48,57,86,312],"group":[49,75,225],"(HYP,":[50],"n=10)":[51],"who":[52,78],"rested":[53],"slept":[55,79],"in":[56,189,242,318,332],"accommodation":[58],"(O2":[59],"concentration":[60,246],"=14.5%;":[61],"3000m)":[63],"\u223c10\u201312":[64],"h/night":[65],"trained":[67,81],"at":[68,82,134,144,231,253,325],"sea":[69,83,165],"level,":[70],"or":[71,295],"control":[74],"(CON,":[76],"n=6)":[77],"level.":[84],"The":[85,147],"period":[87],"was":[88,103,122,128,152,184,214,257,273],"29":[89,335],"nights":[90,336],"VO":[92,156],"THb":[94,102,170,319],"measured":[96,104,129],"before":[97,115],"5\u20137":[99],"days":[100,114],"after.":[101],"using":[105],"carbon":[107],"monoxide":[108],"method":[109,151],"twice":[110],"during":[111],"10":[113],"intervention":[117],"our":[119],"typical":[120],"error":[121],"2.4%.":[123],"Submaximal":[124],"economy":[126,324],"(RE)":[127],"motorized":[132],"treadmill":[133],"12,":[135],"14,":[136],"16":[137],"18":[139,232,254],"km/h":[140,233,255],"with":[141],"4":[142],"min":[143],"each":[145],"speed.":[146],"classic":[148],"Douglas":[149],"bag":[150],"used":[153],"measure":[155],"RESULTS:":[157],"Twenty-nine":[158],"consecutive-nights":[159],"\u201clive":[161],"simulated":[162],"high,":[163],"train":[164],"level\u201d":[166],"did":[167,314],"not":[168,315],"increase":[169],"(HYP-pre":[171,191],"807\u00b164":[172],"vs":[173,179,193,199],"post":[174,180,194,200,265,280],"798\u00b173":[175],"g;":[176],"CON-pre":[177,197],"872\u00b134":[178],"877\u00b124":[181],"g)":[182],"nor":[183],"there":[185],"corresponding":[187],"change":[188],"61.7\u00b13.2":[192],"59.1\u00b14.6":[195],"ml/kg/min;":[196],"59.8\u00b17.1":[198],"56.8\u00b14.5":[201],"ml/kg/min).":[202],"These":[203,285],"results":[204,287],"indicate":[205],"that":[206,291,330],"this":[207,311],"duration":[208],"exposure":[211,306],"insufficient":[215],"stimulate":[216],"increased":[217],"red":[218],"blood":[219,244],"cell":[220],"production.":[221],"Only":[222],"HYP":[224],"had":[226],"5.0%":[228],"improved":[229,323],"RE":[230],"(P":[234],"<":[235],"0.01).":[236],"There":[237],"no":[239],"significant":[240],"changes":[241,317],"submaximal":[243,326],"lactate":[245],"(BLa)":[247],"ventilation":[249],"(VE).":[250],"For":[251],"instance":[252],"BLa":[256],"pre":[258,274],"(HYP":[259,266,275],"6.2\u00b13.2;":[260],"CON":[261,268,277,282],"6.0\u00b12.6":[262],"mmol/L)":[263],"6.1\u00b12.4;":[267],"4.9\u00b11.7":[269],"mmol/L),":[270],"VE":[272],"89.3\u00b113.2;":[276],"81.0\u00b18.2L/min)":[278],"(HYP85.1\u00b110.3;":[281],"80.5\u00b116.7":[283],"L/min).":[284],"two":[286],"exclude":[288],"possibility":[290],"greater":[292],"carbohydrate":[293],"utilization":[294],"reduced":[296],"energy":[297],"requirement":[298],"respiratory":[300],"muscle":[301],"induced":[303],"by":[304],"hypoxia.":[308],"CONCLUSIONS:":[309],"Although":[310],"protocol":[313],"cause":[316],"VO,":[321],"speed":[328],"implies":[329],"sleeping":[331],"for":[334],"can":[337],"enhance":[338],"athletic":[339],"performance.":[340]},"counts_by_year":[],"updated_date":"2026-10-24T09:50:30.924529","created_date":"2016-10-07T00:00:00"}