{"id":"https://openalex.org/W2519002838","doi":null,"title":"Clonal Unit Architecture ofthe Adult Fly Brain","display_name":"Clonal Unit Architecture ofthe Adult Fly Brain","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2519002838","mag":"2519002838"},"language":"en","primary_location":{"id":"mag:2519002838","doi":null,"is_oa":false,"landing_page_url":"https://link.springer.com/chapter/10.1007/978-0-387-78261-4_9","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045205154","display_name":"Kei Ito","orcid":"https://orcid.org/0000-0002-7274-5533","observed_orcids":["https://orcid.org/0000-0002-7274-5533","https://orcid.org/0009-0002-8346-5913"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kei Ito","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5013738307","display_name":"Takeshi Awasaki","orcid":"https://orcid.org/0000-0003-2662-6389","observed_orcids":["https://orcid.org/0000-0003-2662-6389"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Takeshi Awasaki","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2662-6389","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.31304008,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroblasts","display_name":"neuroblasts","score":0.5680000185966492},{"id":"https://openalex.org/keywords/asymmetric-cell-division","display_name":"asymmetric cell division","score":0.8809999823570251},{"id":"https://openalex.org/keywords/mushroom-body","display_name":"mushroom body","score":0.8059999942779541},{"id":"https://openalex.org/keywords/central-complex","display_name":"central complex","score":0.9850000143051147},{"id":"https://openalex.org/keywords/neural-circuits","display_name":"neural circuits","score":0.875}],"concepts":[{"id":"https://openalex.org/C39961270","wikidata":"https://www.wikidata.org/wiki/Q2927095","display_name":"Neuroblast","level":3,"score":0.8832650184631348},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7407694458961487},{"id":"https://openalex.org/C2776038537","wikidata":"https://www.wikidata.org/wiki/Q1362803","display_name":"Mushroom bodies","level":4,"score":0.616271436214447},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.5641366839408875},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5251050591468811},{"id":"https://openalex.org/C113246987","wikidata":"https://www.wikidata.org/wiki/Q1534415","display_name":"Neurite","level":3,"score":0.45845550298690796},{"id":"https://openalex.org/C118403218","wikidata":"https://www.wikidata.org/wiki/Q43283","display_name":"Biological neural network","level":2,"score":0.4558814764022827},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3219960927963257},{"id":"https://openalex.org/C2780104201","wikidata":"https://www.wikidata.org/wiki/Q130888","display_name":"Drosophila melanogaster","level":3,"score":0.25177720189094543},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20736688375473022},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2519002838","doi":null,"is_oa":false,"landing_page_url":"https://link.springer.com/chapter/10.1007/978-0-387-78261-4_9","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1515422163","https://openalex.org/W1894754493","https://openalex.org/W1944839846","https://openalex.org/W1977688141","https://openalex.org/W1980072739","https://openalex.org/W1981666992","https://openalex.org/W1983156044","https://openalex.org/W1993182457","https://openalex.org/W1996582918","https://openalex.org/W2000346699","https://openalex.org/W2003307100","https://openalex.org/W2006229889","https://openalex.org/W2012674191","https://openalex.org/W2017439745","https://openalex.org/W2020011162","https://openalex.org/W2026175377","https://openalex.org/W2028689811","https://openalex.org/W2030233815","https://openalex.org/W2030867907","https://openalex.org/W2041851452","https://openalex.org/W2046544898","https://openalex.org/W2050115159","https://openalex.org/W2050230600","https://openalex.org/W2053050328","https://openalex.org/W2054944848","https://openalex.org/W2057723597","https://openalex.org/W2072354358","https://openalex.org/W2073133778","https://openalex.org/W2075433744","https://openalex.org/W2075754851","https://openalex.org/W2082414547","https://openalex.org/W2086075096","https://openalex.org/W2087767638","https://openalex.org/W2109775042","https://openalex.org/W2110643873","https://openalex.org/W2116692225","https://openalex.org/W2124248841","https://openalex.org/W2129160696","https://openalex.org/W2142228333","https://openalex.org/W2146279063","https://openalex.org/W2148579087","https://openalex.org/W2152437336","https://openalex.org/W2155720250","https://openalex.org/W2159935247","https://openalex.org/W2160777888","https://openalex.org/W2162207411","https://openalex.org/W2167466734","https://openalex.org/W2167534822","https://openalex.org/W2169062325","https://openalex.org/W2184390227","https://openalex.org/W2288900193","https://openalex.org/W2312998717","https://openalex.org/W2614963852","https://openalex.org/W2885856253","https://openalex.org/W2999842854","https://openalex.org/W3091980046","https://openalex.org/W4232755864"],"related_works":["https://openalex.org/W2005735307","https://openalex.org/W2222775905","https://openalex.org/W2123114798","https://openalex.org/W1956275602","https://openalex.org/W4230391143","https://openalex.org/W2321506798","https://openalex.org/W1997473192","https://openalex.org/W2621807433","https://openalex.org/W2024465202","https://openalex.org/W3010382778"],"abstract_inverted_index":{"During":[0],"larval":[1,22],"neurogenesis,":[2],"neuroblasts":[3],"repeat":[4],"asymmetric":[5],"cell":[6,25],"divisions":[7],"to":[8,52,165,171],"generate":[9],"clonally":[10,106],"related":[11,107,185],"progeny.":[12],"When":[13],"the":[14,21,39,45,57,67,94,96,114,137,141,197],"progenyofa":[15],"single":[16],"neuroblast":[17],"is":[18,71,119,134],"visualized":[19],"in":[20,38,47,66,87,113],"brain,":[23,91,117],"their":[24],"bodies":[26],"form":[27,32,50,166],"a":[28,190],"cluster":[29,49],"andtheir":[30],"neurites":[31],"atight":[33],"bundle.":[34],"This":[35],"structure":[36,62],"persists":[37],"adult":[40,148],"brain.":[41,58],"Neurites":[42],"deriving":[43],"from":[44],"cells":[46],"this":[48],"bundles":[51],"innervate":[53],"distinct":[54,167],"areas":[55,89],"of":[56],"Such":[59],"clonal":[60,77,103,138,153,161],"unit":[61],"was":[63],"first":[64],"identified":[65],"mushroom":[68],"body,":[69],"which":[70,118,172],"formed":[72],"by":[73,181],"four":[74],"nearly":[75],"identical":[76],"units":[78,139,154,162,186],"each":[79],"ofwhich":[80],"consists":[81],"ofdiverse":[82],"types":[83],"ofneurons.":[84],"Organised":[85],"structures":[86],"other":[88,173],"ofthe":[90,116,125,147,152,179],"such":[92],"as":[93,203,205],"centralcomplexand":[95],"antennallobe":[97],"projection":[98],"neurons,":[99],"also":[100,112],"consist":[101],"ofdistinct":[102],"units.":[104],"Many":[105],"neural":[108,168,199],"circuits":[109,200],"are":[110,140,155],"observed":[111],"rest":[115],"often":[120],"called":[121],"diffused":[122],"neuropiles":[123],"because":[124],"ap\u00ad":[126],"parent":[127],"lack":[128],"ofclearly":[129],"demarcated":[130],"structures.":[131],"Thus,":[132],"it":[133],"likely":[135],"that":[136],"building":[142,196],"blocks":[143],"ofa":[144],"significant":[145],"portion":[146],"brain":[149,180],"circuits.":[150],"Arborisations":[151],"not":[156],"mutuallyexclusive,":[157],"however.":[158],"Rather,":[159],"several":[160],"contribute":[163,175],"together":[164],"circuit":[169],"units,":[170],"clones":[174],"relatively":[176],"marginally.":[177],"Construction":[178],"combiningsuch":[182],"groups":[183],"ofclonally":[184],"would":[187],"have":[188],"been":[189],"simple":[191],"and":[192],"efficient":[193],"strategy":[194],"for":[195],"complicated":[198],"during":[201,206],"development":[202],"well":[204],"evolution.":[207]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-09-23T00:00:00"}
