{"id":"https://openalex.org/W2518669163","doi":"https://doi.org/10.1021/jacs.6b07833","title":"Investigation of a Catenane with a Responsive Noncovalent Network: Mimicking Long-Range Responses in Proteins","display_name":"Investigation of a Catenane with a Responsive Noncovalent Network: Mimicking Long-Range Responses in Proteins","publication_year":2016,"publication_date":"2016-09-15","ids":{"openalex":"https://openalex.org/W2518669163","doi":"https://doi.org/10.1021/jacs.6b07833","mag":"2518669163","pmid":"https://pubmed.ncbi.nlm.nih.gov/27631725","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5553285"},"language":"en","primary_location":{"id":"doi:10.1021/jacs.6b07833","doi":"https://doi.org/10.1021/jacs.6b07833","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jacs.6b07833","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5553285/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113604061","display_name":"Mee-Kyung Chung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4210163870","display_name":"United States Army Research Office","ror":"https://ror.org/05epdh915","country_code":"US","type":"government","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I166416128","https://openalex.org/I2802705668","https://openalex.org/I4210154437","https://openalex.org/I4210163870"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mee-Kyung Chung","raw_affiliation_strings":["Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States","University of North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States","institution_ids":["https://openalex.org/I4210163870"]},{"raw_affiliation_string":"University of North Carolina","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061302621","display_name":"Peter S. White","orcid":"https://orcid.org/0000-0002-5877-6237","observed_orcids":["https://orcid.org/0000-0002-5877-6237"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4210163870","display_name":"United States Army Research Office","ror":"https://ror.org/05epdh915","country_code":"US","type":"government","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I166416128","https://openalex.org/I2802705668","https://openalex.org/I4210154437","https://openalex.org/I4210163870"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter S. White","raw_affiliation_strings":["Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States","University of North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States","institution_ids":["https://openalex.org/I4210163870"]},{"raw_affiliation_string":"University of North Carolina","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010224391","display_name":"Stephen J. Lee","orcid":"https://orcid.org/0000-0003-4951-9391","observed_orcids":["https://orcid.org/0000-0003-4951-9391"]},"institutions":[{"id":"https://openalex.org/I4210163870","display_name":"United States Army Research Office","ror":"https://ror.org/05epdh915","country_code":"US","type":"government","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I166416128","https://openalex.org/I2802705668","https://openalex.org/I4210154437","https://openalex.org/I4210163870"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen J. Lee","raw_affiliation_strings":["U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States","institution_ids":["https://openalex.org/I4210163870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042519898","display_name":"Michel R. Gagn\u00e9","orcid":"https://orcid.org/0000-0001-8424-5547","observed_orcids":["https://orcid.org/0000-0001-8424-5547"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4210163870","display_name":"United States Army Research Office","ror":"https://ror.org/05epdh915","country_code":"US","type":"government","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I166416128","https://openalex.org/I2802705668","https://openalex.org/I4210154437","https://openalex.org/I4210163870"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michel R. Gagn\u00e9","raw_affiliation_strings":["Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States","institution_ids":["https://openalex.org/I4210163870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034116233","display_name":"Marcey L. Waters","orcid":"https://orcid.org/0000-0002-4917-5755","observed_orcids":["https://orcid.org/0000-0002-4917-5755"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4210163870","display_name":"United States Army Research Office","ror":"https://ror.org/05epdh915","country_code":"US","type":"government","lineage":["https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I166416128","https://openalex.org/I2802705668","https://openalex.org/I4210154437","https://openalex.org/I4210163870"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marcey L. Waters","raw_affiliation_strings":["Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"U.S. Army Research Office, P.O. Box 12211, Research Triangle Park, North Carolina 27709, United States","institution_ids":["https://openalex.org/I4210163870"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5034116233","https://openalex.org/A5042519898"],"corresponding_institution_ids":["https://openalex.org/I114027177","https://openalex.org/I4210163870"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.4656,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.54117788,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"138","issue":"40","first_page":"13344","last_page":"13352"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11419","display_name":"Supramolecular Self-Assembly in Materials","score":0.5044000148773193,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11419","display_name":"Supramolecular Self-Assembly in Materials","score":0.5044000148773193,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10578","display_name":"Supramolecular Chemistry and Complexes","score":0.47920000553131104,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/2-catenane","display_name":"[2]catenane","score":0.9359999895095825},{"id":"https://openalex.org/keywords/self-assembly","display_name":"self-assembly","score":0.6520000100135803},{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.8629999756813049},{"id":"https://openalex.org/keywords/aromatic-interactions","display_name":"aromatic interactions","score":0.925000011920929},{"id":"https://openalex.org/keywords/frustrated-interactions","display_name":"frustrated interactions","score":0.7390000224113464},{"id":"https://openalex.org/keywords/negative-cooperativity","display_name":"negative cooperativity","score":0.9810000061988831},{"id":"https://openalex.org/keywords/responsive-systems","display_name":"responsive systems","score":0.503000020980835}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9647250771522522},{"id":"https://openalex.org/C50837382","wikidata":"https://www.wikidata.org/wiki/Q418744","display_name":"Catenane","level":3,"score":0.855133056640625},{"id":"https://openalex.org/C137277065","wikidata":"https://www.wikidata.org/wiki/Q2915446","display_name":"Non-covalent interactions","level":4,"score":0.4405853748321533},{"id":"https://openalex.org/C204323151","wikidata":"https://www.wikidata.org/wiki/Q905424","display_name":"Range (aeronautics)","level":2,"score":0.4372311234474182},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.42938685417175293},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3688878118991852},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.19211480021476746},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10932108759880066},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.10669693350791931},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000873","descriptor_name":"Anthracenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005998","descriptor_name":"Glycine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1021/jacs.6b07833","doi":"https://doi.org/10.1021/jacs.6b07833","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jacs.6b07833","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},{"id":"pmid:27631725","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27631725","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5553285","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5553285/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Am Chem Soc","raw_type":"Text"},{"id":"pmh:cdr.lib.unc.edu:rf55zd74z","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.17615/fxm9-0v80","pdf_url":null,"source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of the American Chemical Society, 138(40)","raw_type":"Article"},{"id":"doi:10.17615/fxm9-0v80","doi":"https://doi.org/10.17615/fxm9-0v80","is_oa":true,"landing_page_url":"https://doi.org/10.17615/fxm9-0v80","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5553285","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5553285/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Am Chem Soc","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3869512841","display_name":"Investigation of Latent Free Energy in Noncovalent Networks","funder_award_id":"R01GM110017","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320338281","display_name":"Army Research Office","ror":"https://ror.org/05epdh915"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W373661721","https://openalex.org/W1458390031","https://openalex.org/W1967549971","https://openalex.org/W1989291201","https://openalex.org/W1991194470","https://openalex.org/W1994222180","https://openalex.org/W2003412353","https://openalex.org/W2010894119","https://openalex.org/W2014198696","https://openalex.org/W2019431404","https://openalex.org/W2022402563","https://openalex.org/W2029076044","https://openalex.org/W2032281682","https://openalex.org/W2045591683","https://openalex.org/W2045994733","https://openalex.org/W2049819740","https://openalex.org/W2053721311","https://openalex.org/W2054404701","https://openalex.org/W2061469445","https://openalex.org/W2061486876","https://openalex.org/W2065833983","https://openalex.org/W2065849552","https://openalex.org/W2073444730","https://openalex.org/W2083975423","https://openalex.org/W2087871271","https://openalex.org/W2094605637","https://openalex.org/W2096929343","https://openalex.org/W2097855505","https://openalex.org/W2112236272","https://openalex.org/W2116995522","https://openalex.org/W2120520995","https://openalex.org/W2128926770","https://openalex.org/W2129856353","https://openalex.org/W2135187069","https://openalex.org/W2152485983","https://openalex.org/W2171610577","https://openalex.org/W2171755502","https://openalex.org/W2314898186","https://openalex.org/W2315808064","https://openalex.org/W2331452735","https://openalex.org/W2949611276"],"related_works":["https://openalex.org/W6887874603","https://openalex.org/W2133956445","https://openalex.org/W4415566061","https://openalex.org/W2014985598","https://openalex.org/W2079616560","https://openalex.org/W2066002520","https://openalex.org/W2010894119","https://openalex.org/W4393379028","https://openalex.org/W4237106945","https://openalex.org/W2059188685"],"abstract_inverted_index":{"We":[0,84],"report":[1],"a":[2,56,75,96],"functional":[3],"synthetic":[4],"model":[5,18,100],"for":[6,13,80,101],"studying":[7],"the":[8,39,45,61,82],"noncovalent":[9,72],"networks":[10],"(NCNs)":[11],"required":[12],"complex":[14],"protein":[15],"functions.":[16],"The":[17],"[2]-catenane":[19],"is":[20],"self-assembled":[21],"from":[22],"dipeptide":[23],"building":[24],"blocks":[25],"and":[26,34,48,94,98],"contains":[27],"an":[28],"extensive":[29],"network":[30],"of":[31,55,67,77],"hydrogen":[32],"bonds":[33],"aromatic":[35],"interactions.":[36],"Perturbations":[37],"to":[38,86],"catenane":[40],"cause":[41],"compensating":[42],"changes":[43,53],"in":[44,51],"NCNs":[46,64],"structure":[47],"dynamics,":[49],"resulting":[50],"long-distance":[52],"reminiscent":[54],"protein.":[57],"Key":[58],"findings":[59],"include":[60],"notion":[62],"that":[63],"require":[65],"regions":[66],"negative":[68],"cooperativity,":[69],"or":[70],"\"frustrated\"":[71],"interactions,":[73],"as":[74,90],"source":[76],"potential":[78,88],"energy":[79,89,93],"driving":[81],"response.":[83],"refer":[85],"this":[87],"latent":[91],"free":[92],"describe":[95],"mechanistic":[97],"energetic":[99],"responsive":[102],"systems.":[103]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-09-23T00:00:00"}