{"id":"https://openalex.org/W2514218394","doi":null,"title":"POSS\u00cdVEIS BENEF\u00cdCIOS DO \u00d3LEO ESSENCIAL DE Alpinia zerumbet SOBRE OS SINTOMAS NEGATIVOS E COGNITIVOS DA ESQUIZOFRENIA INDUZIDOS PELA ADMINISTRA\u00c7\u00c3O DE CETAMINA EM RATOS","display_name":"POSS\u00cdVEIS BENEF\u00cdCIOS DO \u00d3LEO ESSENCIAL DE Alpinia zerumbet SOBRE OS SINTOMAS NEGATIVOS E COGNITIVOS DA ESQUIZOFRENIA INDUZIDOS PELA ADMINISTRA\u00c7\u00c3O DE CETAMINA EM RATOS","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2514218394","mag":"2514218394"},"language":"pt","primary_location":{"id":"pmh:oai:agregador.ibict.br.BDTD_UFC:oai:www.teses.ufc.br:7737","doi":null,"is_oa":true,"landing_page_url":"https://www.rcaap.pt/detail.jsp?id=oai:agregador.ibict.br.BDTD_UFC:oai:www.teses.ufc.br:7737","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/masterThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.rcaap.pt/detail.jsp?id=oai:agregador.ibict.br.BDTD_UFC:oai:www.teses.ufc.br:7737","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047533065","display_name":"Daniel Sobreira Galdino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Daniel Sobreira Galdino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5047533065"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13090","display_name":"Medicinal Plant Extracts Effects","score":0.014999999664723873,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12347","display_name":"Ginger and Zingiberaceae research","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpinia-zerumbet","display_name":"Alpinia zerumbet","score":0.949999988079071},{"id":"https://openalex.org/keywords/essential-oils","display_name":"essential oils","score":0.9929999709129333},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9340000152587891},{"id":"https://openalex.org/keywords/negative-symptoms","display_name":"negative symptoms","score":0.6919999718666077},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.7260000109672546},{"id":"https://openalex.org/keywords/positive-symptoms","display_name":"positive symptoms","score":0.7279999852180481},{"id":"https://openalex.org/keywords/locomotor-activity","display_name":"locomotor activity","score":0.6629999876022339},{"id":"https://openalex.org/keywords/social-interaction","display_name":"social interaction","score":0.9509999752044678},{"id":"https://openalex.org/keywords/object-recognition-memory","display_name":"object recognition memory","score":0.7070000171661377},{"id":"https://openalex.org/keywords/y-maze-test","display_name":"Y-maze","score":0.8659999966621399},{"id":"https://openalex.org/keywords/antipsychotic-effects","display_name":"antipsychotic effects","score":0.7630000114440918},{"id":"https://openalex.org/keywords/risperidone","display_name":"risperidone","score":0.8970000147819519},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.7400000095367432},{"id":"https://openalex.org/keywords/anxiolytic-effects","display_name":"anxiolytic effects","score":0.5540000200271606},{"id":"https://openalex.org/keywords/sedative-effects","display_name":"sedative effects","score":0.4620000123977661},{"id":"https://openalex.org/keywords/anticonvulsant-activity","display_name":"anticonvulsant activity","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.55503910779953},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39482152462005615}],"mesh":[],"locations_count":6,"locations":[{"id":"pmh:oai:agregador.ibict.br.BDTD_UFC:oai:www.teses.ufc.br:7737","doi":null,"is_oa":true,"landing_page_url":"https://www.rcaap.pt/detail.jsp?id=oai:agregador.ibict.br.BDTD_UFC:oai:www.teses.ufc.br:7737","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"pmh:oai:americanae.aecid.es:1587124","doi":null,"is_oa":true,"landing_page_url":"http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11344","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Biblioteca Digital de Teses e Disserta\u00e7\u00f5es da UFC","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"pmh:oai:americanae.aecid.es:1645442","doi":null,"is_oa":true,"landing_page_url":"http://www.repositorio.ufc.br/handle/riufc/7608","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da Universidade Federal do Cear\u00e1 (UFC)","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"pmh:oai:repositorio.ufc.br:riufc/7608","doi":null,"is_oa":true,"landing_page_url":"http://www.repositorio.ufc.br/handle/riufc/7608","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UFC","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"pmh:oai:www.teses.ufc.br:7737","doi":null,"is_oa":true,"landing_page_url":"http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11344","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Biblioteca Digital de Teses e Disserta\u00e7\u00f5es da UFC","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"mag:2514218394","doi":null,"is_oa":false,"landing_page_url":"http://www.repositorio.ufc.br/bitstream/riufc/7608/1/2013_dis_dsgaldino.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:agregador.ibict.br.BDTD_UFC:oai:www.teses.ufc.br:7737","doi":null,"is_oa":true,"landing_page_url":"https://www.rcaap.pt/detail.jsp?id=oai:agregador.ibict.br.BDTD_UFC:oai:www.teses.ufc.br:7737","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/masterThesis"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":135,"referenced_works":["https://openalex.org/W52823280","https://openalex.org/W61601155","https://openalex.org/W99579187","https://openalex.org/W105318348","https://openalex.org/W200725031","https://openalex.org/W607498431","https://openalex.org/W1481163064","https://openalex.org/W1504579882","https://openalex.org/W1558165107","https://openalex.org/W1559088113","https://openalex.org/W1560740781","https://openalex.org/W1585997112","https://openalex.org/W1589353809","https://openalex.org/W1596948422","https://openalex.org/W1850287535","https://openalex.org/W1954888178","https://openalex.org/W1966203492","https://openalex.org/W1966500625","https://openalex.org/W1971842245","https://openalex.org/W1972294237","https://openalex.org/W1972758435","https://openalex.org/W1972981511","https://openalex.org/W1973371295","https://openalex.org/W1973730102","https://openalex.org/W1975908477","https://openalex.org/W1976104694","https://openalex.org/W1980386735","https://openalex.org/W1980573935","https://openalex.org/W1982283662","https://openalex.org/W1982723311","https://openalex.org/W1982814832","https://openalex.org/W1985745091","https://openalex.org/W1986336245","https://openalex.org/W1986731926","https://openalex.org/W1987400033","https://openalex.org/W1987843838","https://openalex.org/W1988577315","https://openalex.org/W1991637991","https://openalex.org/W1993616139","https://openalex.org/W1995586257","https://openalex.org/W1996254896","https://openalex.org/W1997483502","https://openalex.org/W1999238877","https://openalex.org/W2000460121","https://openalex.org/W2001444209","https://openalex.org/W2001635729","https://openalex.org/W2005459453","https://openalex.org/W2007375338","https://openalex.org/W2009591333","https://openalex.org/W2012112058","https://openalex.org/W2013373204","https://openalex.org/W2015634119","https://openalex.org/W2017267321","https://openalex.org/W2020140782","https://openalex.org/W2021229846","https://openalex.org/W2022725791","https://openalex.org/W2026334669","https://openalex.org/W2026636393","https://openalex.org/W2028884770","https://openalex.org/W2029925498","https://openalex.org/W2030160228","https://openalex.org/W2032058764","https://openalex.org/W2033123684","https://openalex.org/W2034371602","https://openalex.org/W2034952028","https://openalex.org/W2037607491","https://openalex.org/W2037670898","https://openalex.org/W2041474698","https://openalex.org/W2042902270","https://openalex.org/W2043952421","https://openalex.org/W2044657599","https://openalex.org/W2048349699","https://openalex.org/W2048550191","https://openalex.org/W2052480734","https://openalex.org/W2053518393","https://openalex.org/W2056443008","https://openalex.org/W2064375254","https://openalex.org/W2064678154","https://openalex.org/W2065971435","https://openalex.org/W2066507833","https://openalex.org/W2066583262","https://openalex.org/W2071090720","https://openalex.org/W2072441360","https://openalex.org/W2073035754","https://openalex.org/W2074510634","https://openalex.org/W2085360366","https://openalex.org/W2085741304","https://openalex.org/W2086023016","https://openalex.org/W2087184916","https://openalex.org/W2091973569","https://openalex.org/W2093102885","https://openalex.org/W2093410553","https://openalex.org/W2093499985","https://openalex.org/W2093795230","https://openalex.org/W2094492844","https://openalex.org/W2095213614","https://openalex.org/W2099635835","https://openalex.org/W2103127225","https://openalex.org/W2103903531","https://openalex.org/W2105527159","https://openalex.org/W2106676000","https://openalex.org/W2107843728","https://openalex.org/W2113319228","https://openalex.org/W2115571754","https://openalex.org/W2117804236","https://openalex.org/W2132980997","https://openalex.org/W2136012195","https://openalex.org/W2137617988","https://openalex.org/W2140421124","https://openalex.org/W2155796481","https://openalex.org/W2156035025","https://openalex.org/W2158137297","https://openalex.org/W2160470207","https://openalex.org/W2162105640","https://openalex.org/W2165209294","https://openalex.org/W2166256285","https://openalex.org/W2168660234","https://openalex.org/W2168928905","https://openalex.org/W2170631493","https://openalex.org/W2172157926","https://openalex.org/W2319075182","https://openalex.org/W2326261401","https://openalex.org/W2396321123","https://openalex.org/W2402955257","https://openalex.org/W2410145538","https://openalex.org/W2428527701","https://openalex.org/W2442660951","https://openalex.org/W2463320085","https://openalex.org/W2491500840","https://openalex.org/W2526359471","https://openalex.org/W2527721492","https://openalex.org/W2731095024","https://openalex.org/W2775300358","https://openalex.org/W3148499377","https://openalex.org/W3149245474"],"related_works":["https://openalex.org/W7052064086","https://openalex.org/W2602892168","https://openalex.org/W1947890035","https://openalex.org/W7120287601","https://openalex.org/W2418239788","https://openalex.org/W7028246783","https://openalex.org/W2007375338","https://openalex.org/W244044417","https://openalex.org/W2896228168","https://openalex.org/W6998835561"],"abstract_inverted_index":{"Antipsic\u00c3ticos":[0],"representam":[1],"o":[2,48,57,110,190,326],"alicerce":[3],"no":[4,334],"tratamento":[5,335],"da":[6,50,58,77,268,285,311,341],"esquizofrenia,":[7,299],"um":[8],"transtorno":[9],"mental":[10],"grave,":[11],"incapacitante,":[12],"com":[13,143,189],"elevada":[14],"carga":[15],"social.":[16],"A":[17,31,81,282],"esquizofrenia":[18,51,78,126,342],"\u00c3":[19,56,69,84,255,298,310],"uma":[20,53,85,330],"s\u00c3ndrome":[21],"caracterizada":[22],"pela":[23,128,265],"presen\u00c3a":[24],"de":[25,36,60,71,101,104,133,154,158,185,213,228,230,239,244,257,259,278,289,291,316],"sintomas":[26,40,76,120,214,337],"positivos,":[27,121],"negativos":[28,41,122,218,338],"e":[29,42,123,131,168,177,194,221,226,339],"cognitivos.":[30,43],"terapia":[32],"atual":[33],"n\u00c3o":[34,241],"trata":[35],"maneira":[37],"satisfat\u00c3ria":[38],"os":[39,115,173,201,203,249,319],"Um":[44,183],"modelo":[45,303],"relevante":[46],"para":[47,210],"estudo":[49,323],"em":[52,79,98,224,247,253,272],"abordagem":[54,332],"pr\u00c3-cl\u00c3nica":[55],"administra\u00c3\u00c3o":[59,65,129,153,237,266,283,305],"cetamina.":[61,134,155],"Neste":[62],"sentido":[63],"a":[64,152,161,207,211,236,304],"repetida":[66,132,284],"desta":[67],"droga":[68],"capaz":[70,243,277,288],"mimetizar":[72,290],"grande":[73],"parte":[74],"dos":[75,336],"roedores.":[80],"Alpinia":[82],"zerumbet":[83],"planta":[86],"cujo":[87],"\u00c3leo":[88],"essencial":[89],"(OEAZ)":[90],"vem":[91],"apresentando":[92],"importante":[93],"efeito":[94],"antipsic\u00c3tico":[95,191],"como":[96],"evidenciado":[97],"publica\u00c3\u00c3es":[99],"pr\u00c3vias":[100],"nosso":[102],"grupo":[103,184],"pesquisa.":[105],"Com":[106],"base":[107],"nesta":[108],"afirmativa":[109],"presente":[111,322],"trabalho":[112],"objetivou":[113],"determinar":[114],"efeitos":[116],"do":[117,306,321],"OEAZ":[118,144,178,271,307,327],"contra":[119],"cognitivos":[124,222,340],"tipo":[125],"induzidos":[127],"aguda":[130,238,267],"Para":[135],"tanto":[136],"foram":[137,205],"utilizados":[138],"ratos":[139],"Wistar":[140],"machos":[141],"tratados":[142],"100":[145,179],"ou":[146,150,180],"200":[147,181],"mg/kg":[148],"sozinho":[149],"ap\u00c3s":[151],"No":[156],"protocolo":[157],"administra\u00c3\u00c3es":[159],"repetidas":[160],"cetamina":[162,176,240,286],"foi":[163,187,242,262,276,287,308],"administrada":[164],"por":[165,169],"cinco":[166,171],"dias":[167,172],"mais":[170,293],"animais":[174,186,204],"receberam":[175],"mg/kg.":[182],"tratado":[188],"at\u00c3pico":[192],"risperidona":[193],"outro":[195],"recebeu":[196],"solu\u00c3\u00c3o":[197],"salina":[198],"(controle).":[199],"Ap\u00c3s":[200],"tratamentos":[202],"submetidos":[206],"avalia\u00c3\u00c3es":[208],"comportamentais":[209],"determina\u00c3\u00c3o":[212],"positivos":[215],"(atividade":[216],"locomotora),":[217],"(intera\u00c3\u00c3o":[219],"social)":[220],"(labirinto":[223],"Y":[225],"mem\u00c3ria":[227,256,315],"reconhecimento":[229,258],"objetos).":[231],"Os":[232],"resultados":[233,320],"mostraram":[234],"que":[235,261,301,325],"causar":[245],"altera\u00c3\u00c3es":[246,296],"todos":[248],"modelos":[250],"utilizados,":[251],"principalmente":[252,313],"rela\u00c3\u00c3o":[254],"objetos":[260],"inclusive":[263],"melhorada":[264],"droga.":[269],"O":[270],"ambas":[273],"as":[274,295],"doses":[275],"reverter":[279],"estas":[280],"altera\u00c3\u00c3es.":[281],"forma":[292],"fiel":[294],"relacionadas":[297],"sendo":[300],"neste":[302],"superior":[309],"risperidona,":[312],"na":[314],"trabalho.":[317],"Portanto,":[318],"mostram":[324],"pode":[328],"ser":[329],"nova":[331],"farmacol\u00c3gica":[333]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-09-16T00:00:00"}