{"id":"https://openalex.org/W2513707196","doi":"https://doi.org/10.1016/j.jss.2016.08.078","title":"Topical vanadate enhances the repair of median laparotomy incisions","display_name":"Topical vanadate enhances the repair of median laparotomy incisions","publication_year":2016,"publication_date":"2016-09-08","ids":{"openalex":"https://openalex.org/W2513707196","doi":"https://doi.org/10.1016/j.jss.2016.08.078","mag":"2513707196","pmid":"https://pubmed.ncbi.nlm.nih.gov/27979464"},"language":"en","primary_location":{"id":"doi:10.1016/j.jss.2016.08.078","doi":"https://doi.org/10.1016/j.jss.2016.08.078","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jss.2016.08.078","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017090204","display_name":"Sprague W. Hazard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121058860","display_name":"Dickinson College","ror":"https://ror.org/02ydh7m84","country_code":"US","type":"education","lineage":["https://openalex.org/I121058860"]},{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sprague W. Hazard","raw_affiliation_strings":["Department of Anesthesia, Penn State Hershey Medical Center, Hershey, Pennsylvania; Department of Biology, Dickinson College, Carlisle, Pennsylvania","Department of Anesthesia, Penn State Hershey Medical Center, Hershey, Pennsylvania","Department of Biology, Dickinson College, Carlisle, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia, Penn State Hershey Medical Center, Hershey, Pennsylvania; Department of Biology, Dickinson College, Carlisle, Pennsylvania","institution_ids":["https://openalex.org/I121058860","https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Anesthesia, Penn State Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Biology, Dickinson College, Carlisle, Pennsylvania","institution_ids":["https://openalex.org/I121058860"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041307784","display_name":"Charles F. Zwemer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121058860","display_name":"Dickinson College","ror":"https://ror.org/02ydh7m84","country_code":"US","type":"education","lineage":["https://openalex.org/I121058860"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles F. Zwemer","raw_affiliation_strings":["Department of Biology, Dickinson College, Carlisle, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Dickinson College, Carlisle, Pennsylvania","institution_ids":["https://openalex.org/I121058860"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050347972","display_name":"Donald Roy Mackay","orcid":"https://orcid.org/0000-0003-3952-1527","observed_orcids":["https://orcid.org/0000-0003-3952-1527"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald R. Mackay","raw_affiliation_strings":["Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072425635","display_name":"Srinivas V. Koduru","orcid":"https://orcid.org/0000-0001-6827-2908","observed_orcids":["https://orcid.org/0000-0001-6827-2908"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Srinivas V. Koduru","raw_affiliation_strings":["Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056618662","display_name":"Dino J. Ravnic","orcid":"https://orcid.org/0000-0003-2261-5180","observed_orcids":["https://orcid.org/0000-0003-2261-5180"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dino J. Ravnic","raw_affiliation_strings":["Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania. Electronic address: dravnic@hmc.psu.edu","Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania. Electronic address: dravnic@hmc.psu.edu","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111586605","display_name":"H. Paul Ehrlich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Paul Ehrlich","raw_affiliation_strings":["Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Penn State Hershey Medical Center, Hershey, Pennsylvania","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5056618662"],"corresponding_institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":0.3563,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.69310482,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"207","issue":null,"first_page":"102","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.6079000234603882,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.6079000234603882,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10961","display_name":"Hernia repair and management","score":0.3677000105381012,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12906","display_name":"Surgical Sutures and Adhesives","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vanadate","display_name":"vanadate","score":0.7699999809265137},{"id":"https://openalex.org/keywords/sodium-orthovanadate","display_name":"sodium orthovanadate","score":0.9879999756813049},{"id":"https://openalex.org/keywords/topical-wound-treatment","display_name":"topical wound treatment","score":0.5720000267028809},{"id":"https://openalex.org/keywords/laparotomy-incision","display_name":"laparotomy incision","score":0.7979999780654907},{"id":"https://openalex.org/keywords/abdominal-wall-repair","display_name":"abdominal wall repair","score":0.6240000128746033},{"id":"https://openalex.org/keywords/incisional-hernia","display_name":"incisional hernia","score":0.8759999871253967},{"id":"https://openalex.org/keywords/hernia-recurrence","display_name":"hernia recurrence","score":0.8130000233650208},{"id":"https://openalex.org/keywords/wound-tensile-strength","display_name":"wound tensile strength","score":0.8550000190734863},{"id":"https://openalex.org/keywords/connective-tissue-maturation","display_name":"connective tissue maturation","score":0.9399999976158142},{"id":"https://openalex.org/keywords/myofibroblasts","display_name":"myofibroblasts","score":0.9520000219345093},{"id":"https://openalex.org/keywords/alpha-smooth-muscle-actin","display_name":"alpha-smooth muscle actin","score":0.8790000081062317},{"id":"https://openalex.org/keywords/granulation-tissue","display_name":"granulation tissue","score":0.7549999952316284},{"id":"https://openalex.org/keywords/fascial-closure","display_name":"fascial closure","score":0.6880000233650208}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7137650847434998},{"id":"https://openalex.org/C2780778865","wikidata":"https://www.wikidata.org/wiki/Q1130374","display_name":"Laparotomy","level":2,"score":0.6347965002059937},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.5641489028930664},{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.5441452264785767},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5426597595214844},{"id":"https://openalex.org/C2778754067","wikidata":"https://www.wikidata.org/wiki/Q354111","display_name":"Abdominal wall","level":2,"score":0.4971006214618683},{"id":"https://openalex.org/C2993365394","wikidata":"https://www.wikidata.org/wiki/Q5120022","display_name":"Breaking strength","level":2,"score":0.46606165170669556},{"id":"https://openalex.org/C2781116636","wikidata":"https://www.wikidata.org/wiki/Q426228","display_name":"Vanadate","level":2,"score":0.45067620277404785},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4210554361343384},{"id":"https://openalex.org/C2781223772","wikidata":"https://www.wikidata.org/wiki/Q936531","display_name":"Fascia","level":2,"score":0.41374799609184265},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.18045642971992493},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1503707468509674},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069290","descriptor_name":"Incisional Hernia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D000072836","descriptor_name":"Surgical Wound","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000072836","descriptor_name":"Surgical Wound","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003238","descriptor_name":"Connective Tissue","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003238","descriptor_name":"Connective Tissue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007813","descriptor_name":"Laparotomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013718","descriptor_name":"Tensile Strength","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014638","descriptor_name":"Vanadates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014638","descriptor_name":"Vanadates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058107","descriptor_name":"Abdominal Wound Closure Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jss.2016.08.078","doi":"https://doi.org/10.1016/j.jss.2016.08.078","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jss.2016.08.078","pdf_url":null,"source":{"id":"https://openalex.org/S45161156","display_name":"Journal of Surgical Research","issn_l":"0022-4804","issn":["0022-4804","1095-8673"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Research","raw_type":"journal-article"},{"id":"pmid:27979464","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27979464","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of surgical research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1582238871","https://openalex.org/W1599392598","https://openalex.org/W1990933733","https://openalex.org/W1991699537","https://openalex.org/W1999323850","https://openalex.org/W2017261968","https://openalex.org/W2021515559","https://openalex.org/W2028117574","https://openalex.org/W2034121042","https://openalex.org/W2040328392","https://openalex.org/W2046084726","https://openalex.org/W2054990511","https://openalex.org/W2055409553","https://openalex.org/W2055502077","https://openalex.org/W2067130417","https://openalex.org/W2078993382","https://openalex.org/W2082817412","https://openalex.org/W2095267199","https://openalex.org/W2144556777","https://openalex.org/W2464033545"],"related_works":["https://openalex.org/W2054990511","https://openalex.org/W4311960856","https://openalex.org/W4366141322","https://openalex.org/W2321719760","https://openalex.org/W2082817412","https://openalex.org/W2888386916","https://openalex.org/W2046084726","https://openalex.org/W2089612898","https://openalex.org/W4283775264","https://openalex.org/W2083885909"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-09-16T00:00:00"}
