{"id":"https://openalex.org/W2513699673","doi":"https://doi.org/10.1155/2016/1375031","title":"Whole\u2010Genome Expression Analysis and Signal Pathway Screening of Synovium\u2010Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis","display_name":"Whole\u2010Genome Expression Analysis and Signal Pathway Screening of Synovium\u2010Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2513699673","doi":"https://doi.org/10.1155/2016/1375031","mag":"2513699673","pmid":"https://pubmed.ncbi.nlm.nih.gov/27642302","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5014955"},"language":"en","primary_location":{"id":"doi:10.1155/2016/1375031","doi":"https://doi.org/10.1155/2016/1375031","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/1375031","pdf_url":"http://downloads.hindawi.com/journals/sci/2016/1375031.pdf","source":{"id":"https://openalex.org/S27922360","display_name":"Stem Cells International","issn_l":"1687-966X","issn":["1687-966X","1687-9678"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://downloads.hindawi.com/journals/sci/2016/1375031.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015542510","display_name":"Jingyi Hou","orcid":"https://orcid.org/0000-0001-6308-6698","observed_orcids":["https://orcid.org/0000-0001-6308-6698"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingyi Hou","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101731891","display_name":"Yi Ouyang","orcid":"https://orcid.org/0000-0001-7936-6539","observed_orcids":["https://orcid.org/0000-0001-7936-6539"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Ouyang","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100981996","display_name":"Haiquan Deng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haiquan Deng","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100430394","display_name":"Zhong Chen","orcid":"https://orcid.org/0000-0001-6641-751X","observed_orcids":["https://orcid.org/0000-0001-6641-751X"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhong Chen","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101740298","display_name":"Bin Song","orcid":"https://orcid.org/0000-0002-4892-470X","observed_orcids":["https://orcid.org/0000-0002-4892-470X"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Song","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103191608","display_name":"Zhongyu Xie","orcid":"https://orcid.org/0000-0003-2665-6115","observed_orcids":["https://orcid.org/0000-0003-2665-6115"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongyu Xie","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100758592","display_name":"Peng Wang","orcid":"https://orcid.org/0000-0001-5123-4534","observed_orcids":["https://orcid.org/0000-0001-5123-4534"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Wang","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083911731","display_name":"Jinteng Li","orcid":"https://orcid.org/0000-0002-9895-8692","observed_orcids":["https://orcid.org/0000-0002-9895-8692"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinteng Li","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100415562","display_name":"Weiping Li","orcid":"https://orcid.org/0000-0002-7895-4811","observed_orcids":["https://orcid.org/0000-0002-7895-4811"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weiping Li","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":"https://orcid.org/0000-0002-7895-4811","affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046027221","display_name":"Rui Yang","orcid":"https://orcid.org/0000-0001-7457-5163","observed_orcids":["https://orcid.org/0000-0001-7457-5163"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Rui Yang","raw_affiliation_strings":["Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120"],"raw_orcid":"https://orcid.org/0000-0001-7457-5163","affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]},{"raw_affiliation_string":"Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Road West, Guangzhou 510120","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5046027221","https://openalex.org/A5100415562"],"corresponding_institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"],"apc_list":{"value":2570,"currency":"USD","value_usd":2570},"apc_paid":{"value":2570,"currency":"USD","value_usd":2570},"fwci":0.684,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.69026016,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"2016","issue":"1","first_page":"1375031","last_page":"1375031"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9452999830245972,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.03720000013709068,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9369999766349792},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.847000002861023},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.871999979019165},{"id":"https://openalex.org/keywords/p53-signaling-pathway","display_name":"p53 pathway","score":0.9760000109672546},{"id":"https://openalex.org/keywords/jnk","display_name":"JNK","score":0.6150000095367432},{"id":"https://openalex.org/keywords/erk","display_name":"ERK","score":0.9990000128746033},{"id":"https://openalex.org/keywords/p38-mapk","display_name":"p38 MAPK","score":0.8320000171661377},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.8149999976158142}],"concepts":[{"id":"https://openalex.org/C152724338","wikidata":"https://www.wikidata.org/wiki/Q909442","display_name":"KEGG","level":5,"score":0.7078158855438232},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.6044344902038574},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.599704921245575},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.588012158870697},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.5586134195327759},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.5439119935035706},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5257266759872437},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.5022213459014893},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.5014116764068604},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.49922776222229004},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4711384177207947},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4541652798652649},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.44483065605163574},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.4424894452095032},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4351257085800171},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.428041011095047},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3511485159397125},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.26798248291015625},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26512259244918823},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19905641674995422},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.14655789732933044}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1155/2016/1375031","doi":"https://doi.org/10.1155/2016/1375031","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/1375031","pdf_url":"http://downloads.hindawi.com/journals/sci/2016/1375031.pdf","source":{"id":"https://openalex.org/S27922360","display_name":"Stem Cells International","issn_l":"1687-966X","issn":["1687-966X","1687-9678"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells International","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3984231","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5014955","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:27642302","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27642302","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem cells international","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5014955","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5014955/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells Int","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:3d935f635886429ca9572ac003e82017","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/3d935f635886429ca9572ac003e82017","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stem Cells International, Vol 2016 (2016)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2016/1375031","doi":"https://doi.org/10.1155/2016/1375031","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/1375031","pdf_url":"http://downloads.hindawi.com/journals/sci/2016/1375031.pdf","source":{"id":"https://openalex.org/S27922360","display_name":"Stem Cells International","issn_l":"1687-966X","issn":["1687-966X","1687-9678"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cells International","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7868880658","display_name":null,"funder_award_id":"81472102","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321921","display_name":"Natural Science Foundation of Guangdong Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2513699673.pdf","grobid_xml":"https://content.openalex.org/works/W2513699673.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1620420069","https://openalex.org/W1878991695","https://openalex.org/W1974656309","https://openalex.org/W1978555299","https://openalex.org/W1982214865","https://openalex.org/W1984230217","https://openalex.org/W1991546524","https://openalex.org/W1995122819","https://openalex.org/W1998883576","https://openalex.org/W2000097208","https://openalex.org/W2000115558","https://openalex.org/W2000275462","https://openalex.org/W2001951399","https://openalex.org/W2008386900","https://openalex.org/W2023729916","https://openalex.org/W2025371271","https://openalex.org/W2028387032","https://openalex.org/W2038885714","https://openalex.org/W2045961107","https://openalex.org/W2049292651","https://openalex.org/W2054088727","https://openalex.org/W2054248603","https://openalex.org/W2058917707","https://openalex.org/W2073578075","https://openalex.org/W2075235867","https://openalex.org/W2083256869","https://openalex.org/W2090886213","https://openalex.org/W2097577455","https://openalex.org/W2108049638","https://openalex.org/W2110176970","https://openalex.org/W2123014186","https://openalex.org/W2130749714","https://openalex.org/W2133480655","https://openalex.org/W2135510881","https://openalex.org/W2144064419","https://openalex.org/W2147859219","https://openalex.org/W2152348310","https://openalex.org/W2163263636","https://openalex.org/W2184900550","https://openalex.org/W2186707144","https://openalex.org/W2274426412","https://openalex.org/W2295724619","https://openalex.org/W2338465698","https://openalex.org/W2400753478","https://openalex.org/W2465047294","https://openalex.org/W2468628232","https://openalex.org/W4210968471"],"related_works":["https://openalex.org/W2273559097","https://openalex.org/W2024738908","https://openalex.org/W2115565646","https://openalex.org/W1577039056","https://openalex.org/W2121050195","https://openalex.org/W3029381085","https://openalex.org/W3164142193","https://openalex.org/W2417232680","https://openalex.org/W2373068526","https://openalex.org/W4225326920"],"abstract_inverted_index":{"Synovium-derived":[0],"mesenchymal":[1],"stromal":[2],"cells":[3],"(SMSCs)":[4],"may":[5,181],"play":[6],"an":[7],"important":[8],"role":[9],"in":[10,23,39,58,88,125,171],"the":[11,59,64,89,108,119,137,141,155,172,185],"pathogenesis":[12],"of":[13,84,101,140,158,188],"rheumatoid":[14,112,175],"arthritis":[15,113],"(RA)":[16],"and":[17,44,71,94,103,111,117,146,162,177,190],"show":[18],"promise":[19],"for":[20],"therapeutic":[21,193],"applications":[22],"RA.":[24],"In":[25],"this":[26],"study,":[27],"a":[28,147],"whole-genome":[29],"microarray":[30],"analysis":[31,79,105,150],"was":[32,123,133,151],"used":[33,152],"to":[34,63,135,153,183,192],"detect":[35],"differential":[36],"gene":[37],"expression":[38,138,156],"SMSCs":[40],"from":[41],"RA":[42,60,126,189,194],"patients":[43],"healthy":[45],"donors":[46],"(HDs).":[47],"Our":[48,164],"results":[49],"showed":[50,80,106],"that":[51,107,118,167],"there":[52],"were":[53,69,74,115],"4828":[54],"differentially":[55,85,168],"expressed":[56,86,169],"genes":[57,68,73,87,143,170],"group":[61],"compared":[62],"HD":[65],"group;":[66],"3117":[67],"upregulated,":[70],"1711":[72],"downregulated.":[75],"A":[76,98],"Gene":[77],"Ontology":[78],"significantly":[81],"enriched":[82],"terms":[83],"biological":[90],"process,":[91],"cellular":[92],"component,":[93],"molecular":[95],"function":[96],"domains.":[97],"Kyoto":[99],"Encyclopedia":[100],"Genes":[102],"Genomes":[104],"MAPK":[109,173],"signaling":[110,121,179],"pathways":[114,180],"upregulated":[116],"p53":[120,178],"pathway":[122],"downregulated":[124],"SMSCs.":[127],"Quantitative":[128],"real-time":[129],"polymerase":[130],"chain":[131],"reaction":[132],"applied":[134],"verify":[136],"variations":[139],"partial":[142],"mentioned":[144],"above,":[145],"western":[148],"blot":[149],"determine":[154],"levels":[157],"p53,":[159],"p-JNK,":[160],"p-ERK,":[161],"p-p38.":[163],"study":[165],"found":[166],"signaling,":[174],"arthritis,":[176],"help":[182],"explain":[184],"pathogenic":[186],"mechanism":[187],"lead":[191],"SMSC":[195],"applications.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-09-16T00:00:00"}