{"id":"https://openalex.org/W2511568285","doi":null,"title":"ALS PATOF\u0130ZYOLOJ\u0130S\u0130: NEY\u0130, NE KADAR B\u0130L\u0130YORUZ?","display_name":"ALS PATOF\u0130ZYOLOJ\u0130S\u0130: NEY\u0130, NE KADAR B\u0130L\u0130YORUZ?","publication_year":2015,"publication_date":"2015-06-24","ids":{"openalex":"https://openalex.org/W2511568285","mag":"2511568285"},"language":"tr","primary_location":{"id":"pmh:oai:dergipark.gov.tr:article/3003","doi":null,"is_oa":false,"landing_page_url":"http://dergipark.gov.tr/marumj/issue/414/3003","pdf_url":null,"source":{"id":"https://openalex.org/S4306401840","display_name":"DergiPark (Istanbul University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67581229","host_organization_name":"Istanbul University","host_organization_lineage":["https://openalex.org/I67581229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\\n Volume: 21, Issue: 1\\n 102-111\\n \\n","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078959602","display_name":"Kay\u0131han Ulu\u00e7","orcid":"https://orcid.org/0000-0001-6132-2300","observed_orcids":["https://orcid.org/0000-0001-6132-2300"]},"institutions":[{"id":"https://openalex.org/I74897591","display_name":"Marmara University","ror":"https://ror.org/02kswqa67","country_code":"TR","type":"education","lineage":["https://openalex.org/I74897591"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ulu\u00e7, Kay\u0131han","raw_affiliation_strings":["Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye","institution_ids":["https://openalex.org/I74897591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015237525","display_name":"Bar\u0131\u015f \u0130\u015fak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74897591","display_name":"Marmara University","ror":"https://ror.org/02kswqa67","country_code":"TR","type":"education","lineage":["https://openalex.org/I74897591"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u0130\u015fak, Bar\u0131\u015f","raw_affiliation_strings":["Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye","institution_ids":["https://openalex.org/I74897591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039888662","display_name":"T\u00fclin Tanr\u0131da\u011f","orcid":"https://orcid.org/0000-0001-6716-7153","observed_orcids":["https://orcid.org/0000-0001-6716-7153"]},"institutions":[{"id":"https://openalex.org/I74897591","display_name":"Marmara University","ror":"https://ror.org/02kswqa67","country_code":"TR","type":"education","lineage":["https://openalex.org/I74897591"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Tanr\u0131da\u011f, T\u00fclin","raw_affiliation_strings":["Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye","institution_ids":["https://openalex.org/I74897591"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109991620","display_name":"\u00d6nder Us","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74897591","display_name":"Marmara University","ror":"https://ror.org/02kswqa67","country_code":"TR","type":"education","lineage":["https://openalex.org/I74897591"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Us, \u00d6nder","raw_affiliation_strings":["Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marmara \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi, N\u00f6roloji Anabilim Dal\u0131, \u0130stanbul, T\u00fcrkiye","institution_ids":["https://openalex.org/I74897591"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I74897591"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":1.0},{"id":"https://openalex.org/keywords/pathophysiology","display_name":"pathophysiology","score":0.8989999890327454},{"id":"https://openalex.org/keywords/motor-neuron-degeneration","display_name":"motor neuron degeneration","score":0.9599999785423279},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.8619999885559082},{"id":"https://openalex.org/keywords/sporadic-als","display_name":"sporadic ALS","score":0.7429999709129333},{"id":"https://openalex.org/keywords/familial-amyotrophic-lateral-sclerosis","display_name":"familial ALS","score":0.9980000257492065},{"id":"https://openalex.org/keywords/disease-mechanisms","display_name":"disease mechanisms","score":0.4339999854564667},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.5370000004768372}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9533237218856812},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3730381429195404},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.32476890087127686}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:dergipark.gov.tr:article/3003","doi":null,"is_oa":false,"landing_page_url":"http://dergipark.gov.tr/marumj/issue/414/3003","pdf_url":null,"source":{"id":"https://openalex.org/S4306401840","display_name":"DergiPark (Istanbul University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67581229","host_organization_name":"Istanbul University","host_organization_lineage":["https://openalex.org/I67581229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\\n Volume: 21, Issue: 1\\n 102-111\\n \\n","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dergipark.org.tr:article/3003","doi":null,"is_oa":false,"landing_page_url":"https://dergipark.org.tr/en/pub/marumj/article/3003","pdf_url":null,"source":{"id":"https://openalex.org/S4306401840","display_name":"DergiPark (Istanbul University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67581229","host_organization_name":"Istanbul University","host_organization_lineage":["https://openalex.org/I67581229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":65,"referenced_works":["https://openalex.org/W111663151","https://openalex.org/W154713113","https://openalex.org/W179784047","https://openalex.org/W1489838872","https://openalex.org/W1522554854","https://openalex.org/W1564601025","https://openalex.org/W1674757660","https://openalex.org/W1903414318","https://openalex.org/W1940519961","https://openalex.org/W1964177214","https://openalex.org/W1964493422","https://openalex.org/W1966613757","https://openalex.org/W1974741503","https://openalex.org/W1978701238","https://openalex.org/W1978793403","https://openalex.org/W1978972146","https://openalex.org/W1983913371","https://openalex.org/W1988871735","https://openalex.org/W1990350761","https://openalex.org/W1997045117","https://openalex.org/W1997112145","https://openalex.org/W2000273493","https://openalex.org/W2008410324","https://openalex.org/W2013135033","https://openalex.org/W2014229192","https://openalex.org/W2019562518","https://openalex.org/W2020074935","https://openalex.org/W2020914812","https://openalex.org/W2022367303","https://openalex.org/W2025799232","https://openalex.org/W2036454611","https://openalex.org/W2040754808","https://openalex.org/W2042889317","https://openalex.org/W2047024509","https://openalex.org/W2048650123","https://openalex.org/W2050300724","https://openalex.org/W2056644558","https://openalex.org/W2059248106","https://openalex.org/W2061969256","https://openalex.org/W2062618223","https://openalex.org/W2063960864","https://openalex.org/W2065845618","https://openalex.org/W2072127908","https://openalex.org/W2072978915","https://openalex.org/W2077041830","https://openalex.org/W2077962324","https://openalex.org/W2078338206","https://openalex.org/W2081394977","https://openalex.org/W2081524611","https://openalex.org/W2081818708","https://openalex.org/W2085165928","https://openalex.org/W2089456608","https://openalex.org/W2093015515","https://openalex.org/W2096386031","https://openalex.org/W2096894090","https://openalex.org/W2106392233","https://openalex.org/W2110289399","https://openalex.org/W2135522980","https://openalex.org/W2140755496","https://openalex.org/W2149497936","https://openalex.org/W2162674881","https://openalex.org/W2167228645","https://openalex.org/W2268498449","https://openalex.org/W2314689571","https://openalex.org/W4406061011"],"related_works":["https://openalex.org/W6986294356","https://openalex.org/W2794493684","https://openalex.org/W4408220640","https://openalex.org/W2614746846","https://openalex.org/W3012195210","https://openalex.org/W2186898572","https://openalex.org/W2072500896","https://openalex.org/W2094043313","https://openalex.org/W4320712382","https://openalex.org/W598982121"],"abstract_inverted_index":{"Amyotrofik":[0],"lateral":[1],"skleroz":[2],"(ALS)":[3],"esas":[4],"olarak":[5,32],"serebral":[6],"korteks,":[7],"beyin":[8],"sap\u0131":[9],"ve":[10,29,42,46],"spinal":[11],"korddaki":[12],"motor":[13],"n\u00f6ronlar\u0131":[14],"etkileyen":[15],"progresif":[16],"seyirli":[17],"n\u00f6rodejeneratif":[18],"bir":[19,66],"hastal\u0131kt\u0131r.":[20],"\u00c7o\u011fu":[21],"vakan\u0131n":[22],"sporadik":[23,43],"oldu\u011fu":[24,60],"ALS\u2019de":[25],"familyal":[26],"ge\u00e7i\u015f":[27],"%5-10\u2019dur":[28],"bunlar\u0131n":[30],"yakla\u015f\u0131k":[31],"%10-20\u2019sinde":[33],"neden":[34],"s\u00fcperoksid":[35],"dismutaz-1":[36],"enziminde":[37],"meydana":[38],"gelen":[39],"mutasyondur.":[40],"Familyal":[41],"vakalar\u0131n":[44],"klinik":[45],"patolojik":[47],"bulgular\u0131":[48],"birbirlerine":[49],"b\u00fcy\u00fck":[50],"benzerlikler":[51],"g\u00f6stermektedir.":[52],"Bu":[53],"\u00f6zg\u00fcn":[54],"derleme":[55],"yaz\u0131s\u0131nda":[56],"ALS\u2019nin":[57],"patofizyolojisinde":[58],"etkili":[59],"\u00f6ne":[61],"s\u00fcr\u00fclen":[62],"mekanizmalar":[63],"varsay\u0131msal":[64],"t\u00fcmleyici":[65],"model":[67],"ile":[68],"tart\u0131\u015f\u0131lacakt\u0131r.":[69]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-09-16T00:00:00"}