{"id":"https://openalex.org/W2510702102","doi":null,"title":"The Effect of Selenium on Heat Shock Protein 70 Expression in Turkey Embryos.","display_name":"The Effect of Selenium on Heat Shock Protein 70 Expression in Turkey Embryos.","publication_year":2004,"publication_date":"2004-04-19","ids":{"openalex":"https://openalex.org/W2510702102","mag":"2510702102"},"language":"en","primary_location":{"id":"pmh:oai:repository.lib.ncsu.edu:1840.16/2417","doi":null,"is_oa":true,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.16/2417","pdf_url":"http://www.lib.ncsu.edu/resolver/1840.16/2417","source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://www.lib.ncsu.edu/resolver/1840.16/2417","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017396850","display_name":"Rafael Edgardo Rivera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rafael Edgardo Rivera","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5017396850"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11107","display_name":"Selenium in Biological Systems","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11107","display_name":"Selenium in Biological Systems","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.030899999663233757,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12365","display_name":"Effects of Environmental Stressors on Livestock","score":0.014800000004470348,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/selenium","display_name":"selenium","score":0.8730000257492065},{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.9990000128746033},{"id":"https://openalex.org/keywords/turkey-embryos","display_name":"turkey embryos","score":0.9309999942779541},{"id":"https://openalex.org/keywords/heat-stress","display_name":"heat stress","score":0.7820000052452087},{"id":"https://openalex.org/keywords/organic-selenium","display_name":"organic selenium","score":0.48899999260902405},{"id":"https://openalex.org/keywords/yeast-selenium","display_name":"yeast selenium","score":0.6639999747276306},{"id":"https://openalex.org/keywords/glutathione-peroxidase","display_name":"glutathione peroxidase","score":0.9879999756813049},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.6179999709129333},{"id":"https://openalex.org/keywords/embryonic-liver","display_name":"embryonic liver","score":0.7730000019073486},{"id":"https://openalex.org/keywords/poultry-nutrition","display_name":"poultry nutrition","score":0.41600000858306885},{"id":"https://openalex.org/keywords/breeder-hens","display_name":"breeder hens","score":0.5740000009536743},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.49000000953674316},{"id":"https://openalex.org/keywords/molecular-chaperones","display_name":"molecular chaperones","score":0.718999981880188},{"id":"https://openalex.org/keywords/egg-incubation-temperature","display_name":"egg incubation temperature","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.6564384698867798},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.5848584771156311},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.5307564735412598},{"id":"https://openalex.org/C553756173","wikidata":"https://www.wikidata.org/wiki/Q876","display_name":"Selenium","level":2,"score":0.5107121467590332},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4639529585838318},{"id":"https://openalex.org/C137984847","wikidata":"https://www.wikidata.org/wiki/Q1621258","display_name":"Heat shock","level":4,"score":0.46364298462867737},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4582928419113159},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.43068206310272217},{"id":"https://openalex.org/C2781300812","wikidata":"https://www.wikidata.org/wiki/Q178061","display_name":"Shock (circulatory)","level":2,"score":0.42872196435928345},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3885371685028076},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2539074420928955},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15555167198181152},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10671186447143555},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10214567184448242},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:repository.lib.ncsu.edu:1840.16/2417","doi":null,"is_oa":true,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.16/2417","pdf_url":"http://www.lib.ncsu.edu/resolver/1840.16/2417","source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},{"id":"mag:2510702102","doi":null,"is_oa":false,"landing_page_url":"https://repository.lib.ncsu.edu/handle/1840.16/2417","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repository.lib.ncsu.edu:1840.16/2417","doi":null,"is_oa":true,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.16/2417","pdf_url":"http://www.lib.ncsu.edu/resolver/1840.16/2417","source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.7142999768257141}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2510702102.pdf","grobid_xml":"https://content.openalex.org/works/W2510702102.grobid-xml"},"referenced_works_count":71,"referenced_works":["https://openalex.org/W38452351","https://openalex.org/W75780208","https://openalex.org/W266526347","https://openalex.org/W630834609","https://openalex.org/W1453845950","https://openalex.org/W1838717315","https://openalex.org/W1964865323","https://openalex.org/W1965711837","https://openalex.org/W1968830300","https://openalex.org/W1969120383","https://openalex.org/W1972458635","https://openalex.org/W1979191152","https://openalex.org/W1989183053","https://openalex.org/W1991255976","https://openalex.org/W1997086886","https://openalex.org/W1998702326","https://openalex.org/W2001505200","https://openalex.org/W2019307783","https://openalex.org/W2030353979","https://openalex.org/W2035635426","https://openalex.org/W2035967513","https://openalex.org/W2039079779","https://openalex.org/W2040370199","https://openalex.org/W2044300935","https://openalex.org/W2053192223","https://openalex.org/W2058390705","https://openalex.org/W2060194897","https://openalex.org/W2062832120","https://openalex.org/W2064090127","https://openalex.org/W2070198604","https://openalex.org/W2072561392","https://openalex.org/W2083893034","https://openalex.org/W2085562485","https://openalex.org/W2089748605","https://openalex.org/W2092325676","https://openalex.org/W2100115287","https://openalex.org/W2100837269","https://openalex.org/W2101775449","https://openalex.org/W2101983119","https://openalex.org/W2106548523","https://openalex.org/W2112125408","https://openalex.org/W2112164014","https://openalex.org/W2114947773","https://openalex.org/W2121911656","https://openalex.org/W2122529064","https://openalex.org/W2126239899","https://openalex.org/W2128635872","https://openalex.org/W2132958218","https://openalex.org/W2137417707","https://openalex.org/W2137529137","https://openalex.org/W2138807866","https://openalex.org/W2145655909","https://openalex.org/W2148677138","https://openalex.org/W2151135830","https://openalex.org/W2152093485","https://openalex.org/W2154595191","https://openalex.org/W2154616390","https://openalex.org/W2161103001","https://openalex.org/W2161604361","https://openalex.org/W2164063935","https://openalex.org/W2165113979","https://openalex.org/W2170172624","https://openalex.org/W2246873881","https://openalex.org/W2313544530","https://openalex.org/W2315748908","https://openalex.org/W2320737588","https://openalex.org/W2324485828","https://openalex.org/W2335554658","https://openalex.org/W2475762450","https://openalex.org/W2502406684","https://openalex.org/W3180205591"],"related_works":["https://openalex.org/W2060090867","https://openalex.org/W2781924163","https://openalex.org/W2044300935","https://openalex.org/W4401981097","https://openalex.org/W2277406461","https://openalex.org/W2144736891","https://openalex.org/W4289841782","https://openalex.org/W2410725657","https://openalex.org/W2306178131","https://openalex.org/W2055824305"],"abstract_inverted_index":{"The":[0,141,159,192,270,301,436],"optimum":[1],"incubation":[2,299],"environment":[3],"to":[4,36,81,88,98,306,310,332,439,449],"obtain":[5],"the":[6,17,29,63,71,102,145,155,169,186,189,285,292,326,329,334,387,392,491],"best":[7],"poult":[8],"quality":[9],"has":[10,25],"always":[11],"been":[12,26],"an":[13,54,200,422],"important":[14],"issue":[15],"in":[16,46,70,106,134,227,263,386,401,467,489],"turkey":[18,99,107,114],"industry.":[19],"Heat":[20],"shock":[21],"protein":[22,47,442],"70":[23],"(hsp70)":[24],"associated":[27],"with":[28,123,130,325,347,372],"acquisition":[30],"of":[31,96,104,111,151,188,209,260,284,328,363,370,481],"thermal":[32],"tolerance":[33,35],"and":[34,58,101,168,224,249,279,291,317,365,432,444,501],"other":[37,293],"stressors.":[38],"Hsp70":[39],"functions":[40,69],"as":[41,319],"a":[42,90,120,149,245,255,359,366,465],"molecular":[43],"chaperone,":[44],"assisting":[45],"refolding":[48],"after":[49,185,408,418,433],"stress-induced":[50],"denaturation.":[51],"Selenium":[52,203],"is":[53,421,464],"essential":[55],"trace":[56],"mineral":[57],"must":[59],"be":[60],"incorporated":[61],"into":[62],"enzyme":[64],"glutathione":[65],"peroxidase":[66],"(GPx).":[67],"GPx":[68,210,225,342,349,371,399,457,468,482],"GSH/GSSG-px":[72],"antioxidant":[73],"system.":[74],"It":[75],"protects":[76,427],"cells":[77],"from":[78,244,254,499],"damage":[79],"due":[80],"oxidative":[82,486],"stress.":[83,435,460],"This":[84],"study":[85],"was":[86,205,234,295,358],"conducted":[87],"examine":[89],"potential":[91],"relationship":[92],"between":[93,218,351,376],"dietary":[94],"supplementation":[95,454,476],"selenium":[97,126,133,262],"hens":[100,116,142],"expression":[103,223],"hsp70":[105,198,222,364,380],"embryos.":[108],"A":[109],"total":[110],"52":[112],"Nicholas":[113],"breeder":[115,121,238],"were":[117,143,157,161,172,182,195,213,242,252,272,287,304,315,323,339,343,382,395,413],"fed":[118,144,257],"either":[119],"diet":[122],"no":[124,214,373],"supplemental":[125],"or":[127],"one":[128],"supplemented":[129],"0.3ppm":[131],"organic":[132,261],"yeast":[135,264],"(Sel-Plex\u00ae,":[136,265],"Alltech":[137,266],"Inc.,":[138,267],"Nicholasville,":[139,268],"KY).":[140,269],"experimental":[146],"diets":[147],"for":[148,165,177,197,274,312,506],"minimum":[150],"two":[152],"weeks":[153],"before":[154,459],"eggs":[156,160,241,251,271,286,303],"collected.":[158],"incubated":[162,273],"at":[163,175,277,280,289,297,344,396],"37.5\u00b0C":[164,278],"21":[166,275],"days,":[167],"embryos":[170],"then":[171],"heat":[173,434],"stressed":[174,288,302],"40\u00b0C":[176,290],"2":[178],"hr.":[179],"Liver":[180],"samples":[181,194,390,404,412],"collected":[183,243,253,316],"immediately":[184],"termination":[187],"heating":[190],"episode.":[191],"liver":[193,229],"analyzed":[196,206,318],"using":[199,236],"immunoblotting":[201],"procedure.":[202],"activity":[204,226,400,417,458],"by":[207],"determination":[208],"activity.":[211],"There":[212],"significant":[215,348,367,374],"differences":[216,375],"(P>0.05)":[217,361],"treatment":[219],"effects":[220],"on":[221],"embryonic":[228],"samples.":[230],"\\n\\nA":[231],"second":[232],"experiment":[233],"done":[235],"commercial":[237],"flocks.":[239],"100":[240],"non":[246,388,402],"Se-supplemented":[247,389,393,403,411],"flock":[248],"90":[250],"flock,":[256],"0.3":[258],"ppm":[259],"days":[276],"day":[281],"22":[282],"half":[283,294],"kept":[296],"normal":[298,307,441,504],"temperatures.":[300],"returned":[305],"incubator":[308],"temperatures":[309],"recover":[311],"3h.":[313],"Livers":[314],"described":[320],"above.":[321],"They":[322],"compared":[324],"results":[327],"first":[330],"experiments":[331],"see":[333],"results.":[335],"Before":[336],"stress,":[337,474,487],"hsp70levels":[338],"minimal":[340],"while":[341,391,410],"maximal":[345],"levels":[346,350,381,480],"treatments.":[352,377],"During":[353,461],"stress":[354,379,409,462],"(Experiment":[355],"1),":[356],"there":[357,463],"non-significant":[360],"induction":[362],"(P<0.05)":[368,384,415],"decrease":[369,466],"After":[378,473],"significantly":[383,414],"higher":[385],"sample":[394],"pre-stress":[397],"levels.":[398],"did":[405],"not":[406,494],"improve":[407],"increasing":[416],"stress.\\n\\nHsp70":[419],"function":[420,505],"energy":[423,447],"dependent":[424],"reaction,":[425],"which":[426,470,484,488],"newly":[428],"synthesized":[429],"proteins":[430],"during":[431],"cell":[437,492],"needs":[438],"stop":[440],"production":[443],"divert":[445],"its":[446],"sources":[448],"keep":[450],"itself":[451],"alive.":[452],"Se":[453,475],"helped":[455,477],"increase":[456],"activity,":[469,483],"induces":[471],"hsp70.":[472],"maintain":[478],"high":[479],"reduces":[485],"turn,":[490],"does":[493],"need":[495],"long":[496],"term":[497],"protection":[498],"hsp70,":[500],"can":[502],"resume":[503],"embryo":[507],"development.":[508]},"counts_by_year":[],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-09-16T00:00:00"}