{"id":"https://openalex.org/W2510224844","doi":null,"title":"Outcome of sub-acute insulin administration on long-term visuo- spatial and short-term working memory in mice","display_name":"Outcome of sub-acute insulin administration on long-term visuo- spatial and short-term working memory in mice","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2510224844","mag":"2510224844"},"language":"en","primary_location":{"id":"pmh:oai:ajol.info:article/142420","doi":null,"is_oa":true,"landing_page_url":"https://www.ajol.info/index.php/jaaps/article/view/142420","pdf_url":null,"source":{"id":"https://openalex.org/S4212763002","display_name":"Journal of African Association of Physiological Sciences","issn_l":"2315-9987","issn":["2315-9987","2449-108X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2"],"host_organization":"https://openalex.org/P4310321518","host_organization_name":"African Journals OnLine","host_organization_lineage":["https://openalex.org/P4310321518"],"host_organization_lineage_names":["African Journals OnLine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2315-9987","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.ajol.info/index.php/jaaps/article/view/142420","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085657485","display_name":"Isyaku Umar Yarube","orcid":"https://orcid.org/0000-0002-2882-5931","observed_orcids":["https://orcid.org/0000-0002-2882-5931"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I.U. Yarube","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2882-5931","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023620142","display_name":"Joseph Olusegun Ayo","orcid":"https://orcid.org/0000-0001-5683-2672","observed_orcids":["https://orcid.org/0000-0001-5683-2672"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph Olusegun Ayo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5683-2672","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020795502","display_name":"Rabiu Abdussalam Magaji","orcid":"https://orcid.org/0000-0003-3627-7653","observed_orcids":["https://orcid.org/0000-0003-3627-7653"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rabiu Abdussalam Magaji","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3627-7653","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113884195","display_name":"Isma'ila Alhaji Umar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I.A. Umar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158337806","display_name":"Nafisa Yusuf","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nafisa Yusuf","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112885612","display_name":"Abdul Wahab Alhassan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A.W. Alhassan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5005152655","display_name":"M.I.A. Saleh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M.I.A. Saleh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3291,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.59069229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"4","issue":"1","first_page":"41","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.2565999925136566,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.2565999925136566,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.0957999974489212,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.07039999961853027,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.9639999866485596},{"id":"https://openalex.org/keywords/visuospatial-memory","display_name":"visuospatial memory","score":0.9190000295639038},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.7940000295639038},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.8140000104904175},{"id":"https://openalex.org/keywords/brain-insulin","display_name":"brain insulin","score":0.6309999823570251},{"id":"https://openalex.org/keywords/elevated-plus-maze","display_name":"elevated plus maze","score":0.7009999752044678},{"id":"https://openalex.org/keywords/y-maze-test","display_name":"Y-maze","score":0.9810000061988831},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.3700000047683716}],"concepts":[{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.8000919818878174},{"id":"https://openalex.org/C21963081","wikidata":"https://www.wikidata.org/wiki/Q11337567","display_name":"Working memory","level":3,"score":0.7231231331825256},{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.513929545879364},{"id":"https://openalex.org/C179226034","wikidata":"https://www.wikidata.org/wiki/Q18599","display_name":"Short-term memory","level":4,"score":0.4893767237663269},{"id":"https://openalex.org/C43729271","wikidata":"https://www.wikidata.org/wiki/Q3560550","display_name":"Spatial memory","level":4,"score":0.485563725233078},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.46320995688438416},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.4581867456436157},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44365009665489197},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4411028027534485},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3481305241584778},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32257017493247986},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2549143135547638},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.19879409670829773},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.18377694487571716},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.13749068975448608},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:ajol.info:article/142420","doi":null,"is_oa":true,"landing_page_url":"https://www.ajol.info/index.php/jaaps/article/view/142420","pdf_url":null,"source":{"id":"https://openalex.org/S4212763002","display_name":"Journal of African Association of Physiological Sciences","issn_l":"2315-9987","issn":["2315-9987","2449-108X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2"],"host_organization":"https://openalex.org/P4310321518","host_organization_name":"African Journals OnLine","host_organization_lineage":["https://openalex.org/P4310321518"],"host_organization_lineage_names":["African Journals OnLine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2315-9987","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2510224844","doi":null,"is_oa":true,"landing_page_url":"https://www.africaneditors.org/journal/JAAPS/abstract/22775-19317","pdf_url":null,"source":{"id":"https://openalex.org/S4212763002","display_name":"Journal of African Association of Physiological Sciences","issn_l":"2315-9987","issn":["2315-9987","2449-108X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2"],"host_organization":"https://openalex.org/P4310321518","host_organization_name":"African Journals OnLine","host_organization_lineage":["https://openalex.org/P4310321518"],"host_organization_lineage_names":["African Journals OnLine"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of African Association of Physiological Sciences","raw_type":null},{"id":"mag:2572157868","doi":null,"is_oa":false,"landing_page_url":"https://www.ajol.info/index.php/jaaps/article/download/142420/132155","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:ajol.info:article/142420","doi":null,"is_oa":true,"landing_page_url":"https://www.ajol.info/index.php/jaaps/article/view/142420","pdf_url":null,"source":{"id":"https://openalex.org/S4212763002","display_name":"Journal of African Association of Physiological Sciences","issn_l":"2315-9987","issn":["2315-9987","2449-108X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jpps-2"],"host_organization":"https://openalex.org/P4310321518","host_organization_name":"African Journals OnLine","host_organization_lineage":["https://openalex.org/P4310321518"],"host_organization_lineage_names":["African Journals OnLine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2315-9987","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1520721690","https://openalex.org/W1970779072","https://openalex.org/W1978808714","https://openalex.org/W1979987497","https://openalex.org/W1980612924","https://openalex.org/W1981929256","https://openalex.org/W1984139645","https://openalex.org/W1993519646","https://openalex.org/W2010677912","https://openalex.org/W2014508157","https://openalex.org/W2016261115","https://openalex.org/W2022008604","https://openalex.org/W2033704972","https://openalex.org/W2037416030","https://openalex.org/W2039819110","https://openalex.org/W2040245119","https://openalex.org/W2050538855","https://openalex.org/W2054768221","https://openalex.org/W2064836594","https://openalex.org/W2067443877","https://openalex.org/W2067902437","https://openalex.org/W2069474577","https://openalex.org/W2072441360","https://openalex.org/W2074117732","https://openalex.org/W2076760455","https://openalex.org/W2083478268","https://openalex.org/W2090470620","https://openalex.org/W2096522491","https://openalex.org/W2101129883","https://openalex.org/W2107533858","https://openalex.org/W2111270640","https://openalex.org/W2120447295","https://openalex.org/W2135591161","https://openalex.org/W2143605092","https://openalex.org/W2147878631","https://openalex.org/W2155253745","https://openalex.org/W2155990560","https://openalex.org/W2163772343","https://openalex.org/W2246454883","https://openalex.org/W2337068081","https://openalex.org/W4378175574"],"related_works":["https://openalex.org/W4390242819","https://openalex.org/W2499393379","https://openalex.org/W2592669355","https://openalex.org/W1964216200","https://openalex.org/W3155732687","https://openalex.org/W7221265636","https://openalex.org/W2035230006","https://openalex.org/W2092362285","https://openalex.org/W2074353151","https://openalex.org/W1981929256"],"abstract_inverted_index":{"Background:":[0],"In":[1,103,123],"the":[2,13,26,41,104,113,121,124,144,150,202,210],"past,":[3],"insulin":[4,23,45,95,98,151,217],"was":[5,37,132,162,213],"considered":[6],"a":[7],"peripheral":[8],"hormone,":[9],"unable":[10],"to":[11,39,79,169],"affect":[12,221],"central":[14],"nervous":[15],"system.":[16],"Now,":[17],"it":[18,29],"is":[19],"well":[20],"established":[21],"that":[22,215],"occurs":[24],"in":[25,143,149,172,229],"brain":[27],"where":[28],"exerts":[30],"regulatory":[31],"and":[32,50,77,83,109,138,155,178,184,189,197,225],"trophic":[33],"effects.":[34],"This":[35],"study":[36],"undertaken":[38],"determine":[40,80],"effect":[42],"of":[43,67,128,195],"sub-acute":[44,216,240],"administration":[46,218],"on":[47],"long-term":[48,81,222,232],"visuo-spatial":[49,82,223,233],"short-term":[51,84,226,235],"working":[52,86,227,238],"memory.Methods:":[53],"Twenty":[54],"four":[55],"mice,":[56],"weighing":[57],"between":[58,120,139,209],"18":[59],"\u2013":[60],"22":[61],"g,":[62],"were":[63,71,112,200],"used.":[64],"Two":[65],"groups":[66,161],"six":[68],"mice":[69,148],"each":[70],"used":[72],"during":[73],"elevated":[74,105],"plus":[75,106],"maze":[76],"Y-maze,":[78],"spatial":[85,236],"memory,":[87,234,237,239],"respectively.":[88],"Control":[89],"group":[90,96],"received":[91,97],"deionized":[92],"water,":[93],"while":[94],"at":[99],"10":[100],"I.U./kg/day,":[101],"subcutaneously.Results:":[102],"maze,":[107],"acquisition":[108],"retention":[110],"latencies":[111],"same":[114,203],"(P":[115,134,164,204],">":[116,135,205],"0.05)":[117,136,166,206],"when":[118,167,207],"compared":[119,168,208],"groups.":[122,140],"Y-maze":[125],"test,":[126],"number":[127],"entries":[129],"into":[130],"arms":[131],"similar":[133],"within":[137],"Time":[141],"spent":[142,171],"novel":[145],"arm":[146,173],"by":[147],"(103.83":[152],"\u00b17.4":[153],"seconds)":[154,160],"control":[156],"(108.00":[157],"\u00b1":[158,176,180,187,191],"13.6":[159],"higher":[163],"<":[165],"time":[170],"A":[174],"(68.33":[175],"10.0":[177],"74.50":[179],"5.6":[181],"seconds,":[182],"respectively)":[183],"B":[185],"(59.17":[186],"9.5":[188],"69.67":[190],"10.7,":[192],"respectively).":[193],"Number":[194],"triads":[196],"percent":[198],"alternations":[199],"also":[201],"groups.Conclusion:":[211],"It":[212],"concluded,":[214],"did":[219],"not":[220],"memory":[224,228],"mice.Keywords:":[230],"insulin,":[231],"treatment":[241]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-09-16T00:00:00"}
