{"id":"https://openalex.org/W2509946342","doi":"https://doi.org/10.1212/wnl.0000000000003094","title":"Predicting Alzheimer disease from a blood-based biomarker profile","display_name":"Predicting Alzheimer disease from a blood-based biomarker profile","publication_year":2016,"publication_date":"2016-08-18","ids":{"openalex":"https://openalex.org/W2509946342","doi":"https://doi.org/10.1212/wnl.0000000000003094","mag":"2509946342","pmid":"https://pubmed.ncbi.nlm.nih.gov/27534714"},"language":"en","primary_location":{"id":"doi:10.1212/wnl.0000000000003094","doi":"https://doi.org/10.1212/wnl.0000000000003094","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.0000000000003094","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080491480","display_name":"Samantha C. Burnham","orcid":"https://orcid.org/0000-0003-4805-5193","observed_orcids":["https://orcid.org/0000-0003-4805-5193"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Samantha C. Burnham","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022818431","display_name":"Christopher Cleon Rowe","orcid":"https://orcid.org/0000-0003-3910-2453","observed_orcids":["https://orcid.org/0000-0003-3910-2453"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Christopher C. Rowe","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":null,"display_name":"David Baker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David Baker","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038374630","display_name":"Ashley Ian Bush","orcid":"https://orcid.org/0000-0001-8259-9069","observed_orcids":["https://orcid.org/0000-0001-8259-9069"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ashley I. Bush","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017855145","display_name":"James D. Doecke","orcid":"https://orcid.org/0000-0003-2863-0293","observed_orcids":["https://orcid.org/0000-0003-2863-0293"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"James D. Doecke","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062154870","display_name":"Noel Garry Faux","orcid":"https://orcid.org/0000-0003-4594-8818","observed_orcids":["https://orcid.org/0000-0003-4594-8818"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Noel G. Faux","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084206283","display_name":"Simon Matthew Laws","orcid":"https://orcid.org/0000-0002-4355-7082","observed_orcids":["https://orcid.org/0000-0002-4355-7082"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Simon M. Laws","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065618928","display_name":"Ralph Nigel Martins","orcid":"https://orcid.org/0000-0002-4828-9363","observed_orcids":["https://orcid.org/0000-0002-4828-9363"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ralph N. Martins","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064879007","display_name":"Paul T. Maruff","orcid":"https://orcid.org/0000-0002-6947-9537","observed_orcids":["https://orcid.org/0000-0002-6947-9537"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Paul Maruff","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055618260","display_name":"S. Lance Macaulay","orcid":"https://orcid.org/0000-0001-5069-9516","observed_orcids":["https://orcid.org/0000-0001-5069-9516"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"S. Lance Macaulay","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061541359","display_name":"Stephanie Ruth Rainey\u2010Smith","orcid":"https://orcid.org/0000-0001-7328-9624","observed_orcids":["https://orcid.org/0000-0001-7328-9624","https://orcid.org/0000-0001-7064-9209"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Stephanie Rainey-Smith","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006706169","display_name":"Greg R. Savage","orcid":"https://orcid.org/0000-0002-5895-1947","observed_orcids":["https://orcid.org/0000-0002-5895-1947"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Greg Savage","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107927449","display_name":"David J. Ames","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David Ames","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047385288","display_name":"Colin Louis Masters","orcid":"https://orcid.org/0000-0003-3072-7940","observed_orcids":["https://orcid.org/0000-0003-3072-7940"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Colin L. Masters","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"middle","author":{"id":null,"display_name":"William Wilson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"William Wilson","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058052951","display_name":"Victor L. Villemagne","orcid":"https://orcid.org/0000-0002-5832-9875","observed_orcids":["https://orcid.org/0000-0002-5832-9875"]},"institutions":[{"id":"https://openalex.org/I139829854","display_name":"Mental Health Research Institute","ror":"https://ror.org/041684t28","country_code":"AU","type":"facility","lineage":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I242743682","display_name":"Florey Institute of Neuroscience and Mental Health","ror":"https://ror.org/03a2tac74","country_code":"AU","type":"facility","lineage":["https://openalex.org/I165779595","https://openalex.org/I242743682"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210163497","display_name":"Austin Health","ror":"https://ror.org/05dbj6g52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Victor L. Villemagne","raw_affiliation_strings":["From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From eHealth (S.C.B.), CSIRO Health and Biosecurity, Floreat; Department of Nuclear Medicine and Centre for PET (C.C.R.), Austin Health, Heidelberg; Department of Medicine (C.C.R., V.L.V.), Austin Health, University of Melbourne, Heidelberg, Australia; Janssen Research and Development (D.B.), Titusville, NJ; Mental Health Research Institute (A.I.B., N.G.F.), Academic Unit for Psychiatry of Old Age, Department of Psychiatry (D.A.), and The Florey Institute (C.L.M., V.L.V.), University of Melbourne,","institution_ids":["https://openalex.org/I139829854","https://openalex.org/I165779595","https://openalex.org/I242743682","https://openalex.org/I4210142128","https://openalex.org/I4210163497"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.7377,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.9486757,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"87","issue":"11","first_page":"1093","last_page":"1101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9660000205039978},{"id":"https://openalex.org/keywords/mild-cognitive-impairment","display_name":"mild cognitive impairment","score":0.9390000104904175},{"id":"https://openalex.org/keywords/disease-progression-prediction","display_name":"disease progression prediction","score":0.7699999809265137},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.7739999890327454},{"id":"https://openalex.org/keywords/memory-decline","display_name":"memory decline","score":0.8190000057220459},{"id":"https://openalex.org/keywords/preclinical-alzheimer-s-disease","display_name":"preclinical Alzheimer's disease","score":0.8100000023841858},{"id":"https://openalex.org/keywords/pittsburgh-compound-b-pet","display_name":"Pittsburgh compound B PET","score":0.6380000114440918}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7160910367965698},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.7062790393829346},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6213766932487488},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6123818755149841},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.5720584392547607},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5708138346672058},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4866519570350647},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.45885685086250305},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.446735143661499},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.32496321201324463},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07015380263328552},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001774","descriptor_name":"Blood Chemical Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1212/wnl.0000000000003094","doi":"https://doi.org/10.1212/wnl.0000000000003094","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.0000000000003094","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},{"id":"pmid:27534714","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27534714","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"Journal Article"},{"id":"pmh:oai:alma.61MUN_INST:11135618830007891","doi":null,"is_oa":false,"landing_page_url":"https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Predicting-Alzheimer-disease-from-a-blood-based/991005541893807891","pdf_url":null,"source":{"id":"https://openalex.org/S4306400274","display_name":"Murdoch University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I176790772","host_organization_name":"Murdoch University","host_organization_lineage":["https://openalex.org/I176790772"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:researchrepository.murdoch.edu.au:60822","doi":null,"is_oa":false,"landing_page_url":"https://researchrepository.murdoch.edu.au/id/eprint/60822/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400274","display_name":"Murdoch University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I176790772","host_organization_name":"Murdoch University","host_organization_lineage":["https://openalex.org/I176790772"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Burnham, S.C., Rowe, C.C., Baker, D., Bush, A.I., Doecke, J.D., Faux, N.G., Laws, S.M., Martins, R.N., Maruff, P., Macaulay, S.L., Rainey-Smith, S. <https://researchrepository.murdoch.edu.au/view/author/Rainey-Smith, Stephanie.html>, Savage, G., Ames, D., Masters, C.L., Wilson, W. and Villemagne, V.L. (2016) Predicting Alzheimer disease from a blood-based biomarker profile. Neurology, 87 (11). pp. 1093-1101.","raw_type":"Journal Article"},{"id":"pmh:oai:ro.ecu.edu.au:ecuworkspost2013-3215","doi":null,"is_oa":false,"landing_page_url":"https://ro.ecu.edu.au/ecuworkspost2013/2211","pdf_url":null,"source":{"id":"https://openalex.org/S4306401966","display_name":"Edith Cowan University Research Online (Edith Cowan University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I12079687","host_organization_name":"Edith Cowan University","host_organization_lineage":["https://openalex.org/I12079687"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research outputs 2014 to 2021","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.75,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W273955616","https://openalex.org/W1484920908","https://openalex.org/W1866881754","https://openalex.org/W1976942091","https://openalex.org/W1988122824","https://openalex.org/W1994247505","https://openalex.org/W2003569140","https://openalex.org/W2018785940","https://openalex.org/W2040174321","https://openalex.org/W2055649795","https://openalex.org/W2058690573","https://openalex.org/W2074427084","https://openalex.org/W2087011519","https://openalex.org/W2088101394","https://openalex.org/W2096321911","https://openalex.org/W2097452416","https://openalex.org/W2111774300","https://openalex.org/W2113518834","https://openalex.org/W2115799070","https://openalex.org/W2119929275","https://openalex.org/W2129497119","https://openalex.org/W2130006532","https://openalex.org/W2130126582","https://openalex.org/W2134711807","https://openalex.org/W2142864721","https://openalex.org/W2145126338","https://openalex.org/W2151384687","https://openalex.org/W2156220037","https://openalex.org/W2159122349","https://openalex.org/W2167712478","https://openalex.org/W2257526256","https://openalex.org/W2582743722","https://openalex.org/W3086315876","https://openalex.org/W3134873896","https://openalex.org/W4254703930","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1980613871","https://openalex.org/W1988122824","https://openalex.org/W6989609770","https://openalex.org/W4416551480","https://openalex.org/W4303647524","https://openalex.org/W2011440365","https://openalex.org/W7162054619","https://openalex.org/W4323348682","https://openalex.org/W7221577822","https://openalex.org/W2888433054"],"abstract_inverted_index":{"OBJECTIVE:":[0],"We":[1,42,100],"assessed":[2,101],"a":[3,92,218],"blood-based":[4,45,220],"signature,":[5],"which":[6],"previously":[7],"demonstrated":[8],"high":[9,15,85,107,135,162,199],"accuracy":[10,104],"at":[11,30,76,125,238,244],"stratifying":[12],"individuals":[13,29,80,237],"with":[14,55,133,144,157,172,188,197,209],"or":[16,119],"low":[17,87,109,146,177,211],"neocortical":[18],"\u03b2-amyloid":[19],"burden":[20],"(NAB),":[21],"to":[22,34,73,115,122,140,167],"determine":[23],"whether":[24],"it":[25],"could":[26],"also":[27,229],"identify":[28],"risk":[31,239],"of":[32,94,105,131,142,154,169,204,226,240],"progression":[33,114],"Alzheimer":[35],"disease":[36,234],"(AD)":[37],"within":[38],"54":[39],"months.":[40],"METHODS:":[41],"generated":[43],"the":[44,61,102,106,155,170,245],"signature":[46,221],"for":[47,191],"585":[48],"healthy":[49],"controls":[50],"(HCs)":[51],"and":[52,65,86,108,233,247],"74":[53],"participants":[54,156,171],"mild":[56,116],"cognitive":[57,117,231],"impairment":[58,118],"(MCI)":[59],"from":[60],"Australian":[62],"Imaging,":[63],"Biomarkers":[64],"Lifestyle":[66],"Study":[67],"who":[68,159,174],"underwent":[69],"clinical":[70,123],"reclassification":[71,124],"(blinded":[72],"biomarker":[74],"findings)":[75],"54-month":[77,126],"follow-up.":[78,127],"The":[79],"were":[81],"split":[82],"into":[83],"estimated":[84,134,145,161,176,198,210],"NAB":[88,110,136,147,163,178,200,227],"groups":[89],"based":[90,112],"on":[91,113],"cutoff":[93],"1.5":[95],"standardized":[96],"uptake":[97],"value":[98],"ratio.":[99],"predictive":[103],"groupings":[111],"AD":[120,243],"according":[121],"RESULTS:":[128],"Twelve":[129],"percent":[130,153],"HCs":[132,143],"progressed":[137,164],"in":[138,165,186],"comparison":[139,166],"5%":[141,168],"(odds":[148,179],"ratio":[149,180],"=":[150,181],"2.4).":[151],"Forty":[152],"MCI":[158,173],"had":[160,175,201],"12.3).":[182],"These":[183,214],"ratios":[184],"are":[185],"line":[187],"those":[189,208],"reported":[190],"Pittsburgh":[192],"compound":[193],"B-PET":[194],"results.":[195],"Individuals":[196],"faster":[202],"rates":[203],"memory":[205],"decline":[206,232],"than":[207],"NAB.":[212],"CONCLUSION:":[213],"findings":[215],"suggest":[216],"that":[217],"simple":[219],"not":[222],"only":[223],"provides":[224],"estimates":[225],"but":[228],"predicts":[230],"progression,":[235],"identifying":[236],"progressing":[241],"toward":[242],"prodromal":[246],"preclinical":[248],"stages.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-09-16T00:00:00"}