{"id":"https://openalex.org/W2508855893","doi":"https://doi.org/10.1111/clr.12950","title":"The effect of experimental osteoporosis on bone regeneration: part 2, proteomics results","display_name":"The effect of experimental osteoporosis on bone regeneration: part 2, proteomics results","publication_year":2016,"publication_date":"2016-09-01","ids":{"openalex":"https://openalex.org/W2508855893","doi":"https://doi.org/10.1111/clr.12950","mag":"2508855893","pmid":"https://pubmed.ncbi.nlm.nih.gov/27580862"},"language":"en","primary_location":{"id":"doi:10.1111/clr.12950","doi":"https://doi.org/10.1111/clr.12950","is_oa":false,"landing_page_url":"https://doi.org/10.1111/clr.12950","pdf_url":null,"source":{"id":"https://openalex.org/S122069063","display_name":"Clinical Oral Implants Research","issn_l":"0905-7161","issn":["0905-7161","1600-0501"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Oral Implants Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003143284","display_name":"Elena Calciolari","orcid":"https://orcid.org/0000-0001-8781-1997","observed_orcids":["https://orcid.org/0000-0001-8781-1997"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. Calciolari","raw_affiliation_strings":["Centre for Clinical Oral Research, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (QMUL), London, UK","Periodontology Department, UCL Eastman Dental Institute, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Clinical Oral Research, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (QMUL), London, UK","institution_ids":["https://openalex.org/I166337079"]},{"raw_affiliation_string":"Periodontology Department, UCL Eastman Dental Institute, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091740983","display_name":"Nikos Mardas","orcid":"https://orcid.org/0000-0002-6841-458X","observed_orcids":["https://orcid.org/0000-0002-6841-458X"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N. Mardas","raw_affiliation_strings":["Centre for Adult Oral Health Bart's & The London School of Dentistry & Medicine Queen Mary University of London (QMUL) London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Adult Oral Health Bart's & The London School of Dentistry & Medicine Queen Mary University of London (QMUL) London UK","institution_ids":["https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082340593","display_name":"Xanthippi E. Dereka","orcid":"https://orcid.org/0000-0002-9142-8613","observed_orcids":["https://orcid.org/0000-0002-9142-8613"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"X. Dereka","raw_affiliation_strings":["Department of Periodontology, National and Kapodistrian University of Athens, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology, National and Kapodistrian University of Athens, Athens, Greece","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041216749","display_name":"Athanasios K. Anagnostopoulos","orcid":"https://orcid.org/0000-0001-5161-7850","observed_orcids":["https://orcid.org/0000-0001-5161-7850"]},"institutions":[{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"A. K. Anagnostopoulos","raw_affiliation_strings":["Proteomics Research Unit, Centre of Basic Research II, Biomedical Research Foundation of the Academy of Athens, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Proteomics Research Unit, Centre of Basic Research II, Biomedical Research Foundation of the Academy of Athens, Athens, Greece","institution_ids":["https://openalex.org/I4210093138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005389679","display_name":"George Th. Tsangaris","orcid":"https://orcid.org/0000-0002-5371-4758","observed_orcids":["https://orcid.org/0000-0002-5371-4758"]},"institutions":[{"id":"https://openalex.org/I4210093138","display_name":"Biomedical Research Foundation of the Academy of Athens","ror":"https://ror.org/00gban551","country_code":"GR","type":"nonprofit","lineage":["https://openalex.org/I4210093138"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"G. T. Tsangaris","raw_affiliation_strings":["Proteomics Research Unit, Centre of Basic Research II, Biomedical Research Foundation of the Academy of Athens, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Proteomics Research Unit, Centre of Basic Research II, Biomedical Research Foundation of the Academy of Athens, Athens, Greece","institution_ids":["https://openalex.org/I4210093138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078853919","display_name":"Nikolaos Donos","orcid":"https://orcid.org/0000-0002-4117-9073","observed_orcids":["https://orcid.org/0000-0002-4117-9073"]},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"N. Donos","raw_affiliation_strings":["Centre for Clinical Oral Research, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (QMUL), London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Clinical Oral Research, Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London (QMUL), London, UK","institution_ids":["https://openalex.org/I166337079"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5078853919"],"corresponding_institution_ids":["https://openalex.org/I166337079"],"apc_list":{"value":5170,"currency":"USD","value_usd":5170},"apc_paid":null,"fwci":4.7092,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.94520013,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"28","issue":"9","first_page":"e135","last_page":"e145"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10359","display_name":"Dental Implant Techniques and Outcomes","score":0.5029000043869019,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10359","display_name":"Dental Implant Techniques and Outcomes","score":0.5029000043869019,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.43140000104904175,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.027799999341368675,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.9179999828338623},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.8550000190734863},{"id":"https://openalex.org/keywords/critical-sized-bone-defects","display_name":"critical-size bone defect","score":0.6890000104904175},{"id":"https://openalex.org/keywords/calvarial-defect","display_name":"calvarial defect","score":0.7139999866485596},{"id":"https://openalex.org/keywords/guided-bone-regeneration","display_name":"guided bone regeneration","score":0.8420000076293945},{"id":"https://openalex.org/keywords/ovariectomy","display_name":"ovariectomy","score":0.8939999938011169},{"id":"https://openalex.org/keywords/low-calcium-diet","display_name":"low calcium diet","score":0.984000027179718},{"id":"https://openalex.org/keywords/proteomics","display_name":"proteomics","score":0.718999981880188},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6140000224113464},{"id":"https://openalex.org/keywords/osteogenic-differentiation","display_name":"osteogenic differentiation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/deproteinized-bovine-bone-mineral","display_name":"deproteinized bovine bone mineral","score":0.8230000138282776},{"id":"https://openalex.org/keywords/collagen-membrane","display_name":"collagen membrane","score":0.8939999938011169}],"concepts":[{"id":"https://openalex.org/C8264082","wikidata":"https://www.wikidata.org/wiki/Q7113259","display_name":"Ovariectomized rat","level":3,"score":0.7599560022354126},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.7291138768196106},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.5754067301750183},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.5373733043670654},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.5134090185165405},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.505406379699707},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48987430334091187},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4810086190700531},{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.47915858030319214},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.388729989528656},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3545520305633545},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2613743543624878},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24611711502075195},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19665229320526123},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.16714602708816528},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09223765134811401},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07280474901199341}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001861","descriptor_name":"Bone Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D048091","descriptor_name":"Guided Tissue Regeneration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/clr.12950","doi":"https://doi.org/10.1111/clr.12950","is_oa":false,"landing_page_url":"https://doi.org/10.1111/clr.12950","pdf_url":null,"source":{"id":"https://openalex.org/S122069063","display_name":"Clinical Oral Implants Research","issn_l":"0905-7161","issn":["0905-7161","1600-0501"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Oral Implants Research","raw_type":"journal-article"},{"id":"pmid:27580862","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27580862","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical oral implants research","raw_type":"Journal Article"},{"id":"pmh:oai:qmro.qmul.ac.uk:123456789/15162","doi":null,"is_oa":false,"landing_page_url":"http://qmro.qmul.ac.uk/xmlui/handle/123456789/15162","pdf_url":null,"source":{"id":"https://openalex.org/S4306400530","display_name":"Queen Mary Research Online (Queen Mary University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I166337079","host_organization_name":"Queen Mary University of London","host_organization_lineage":["https://openalex.org/I166337079"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320335357","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W142932259","https://openalex.org/W1494307075","https://openalex.org/W1498671062","https://openalex.org/W1521778371","https://openalex.org/W1571696828","https://openalex.org/W1920171370","https://openalex.org/W1978961990","https://openalex.org/W1981958853","https://openalex.org/W1986131449","https://openalex.org/W1988046419","https://openalex.org/W1992180597","https://openalex.org/W1993321158","https://openalex.org/W2000706451","https://openalex.org/W2003681585","https://openalex.org/W2021008994","https://openalex.org/W2029616854","https://openalex.org/W2035100455","https://openalex.org/W2036887494","https://openalex.org/W2041275261","https://openalex.org/W2043070543","https://openalex.org/W2051583212","https://openalex.org/W2052218228","https://openalex.org/W2053570594","https://openalex.org/W2055864323","https://openalex.org/W2056995333","https://openalex.org/W2058352802","https://openalex.org/W2062427606","https://openalex.org/W2067119056","https://openalex.org/W2070466054","https://openalex.org/W2079990197","https://openalex.org/W2082164640","https://openalex.org/W2086495450","https://openalex.org/W2097767628","https://openalex.org/W2100564021","https://openalex.org/W2108143331","https://openalex.org/W2125272276","https://openalex.org/W2126497169","https://openalex.org/W2128635872","https://openalex.org/W2130064617","https://openalex.org/W2138617880","https://openalex.org/W2140836551","https://openalex.org/W2149642623","https://openalex.org/W2151841676","https://openalex.org/W2158135268","https://openalex.org/W2162032757","https://openalex.org/W2162103775","https://openalex.org/W2331823648","https://openalex.org/W4379781512"],"related_works":["https://openalex.org/W2515261433","https://openalex.org/W7064241793","https://openalex.org/W2164474307","https://openalex.org/W3118261781","https://openalex.org/W1987103142","https://openalex.org/W2066890382","https://openalex.org/W1992306048","https://openalex.org/W7008018607","https://openalex.org/W2274115852","https://openalex.org/W4410027190"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"identify":[2],"and":[3,25,44,74,81,91,118,128,137,151,163,184,210,233],"describe":[4],"protein":[5],"expression":[6],"in":[7,23,134,147,154,177,216],"a":[8,47,75,175,223,226,234],"Wistar":[9,34],"rat":[10],"calvarial":[11,63],"critical":[12],"size":[13],"defect":[14],"(CSD)":[15],"model":[16],"following":[17],"treatment":[18],"with":[19,46,67,111],"guided":[20],"bone":[21,70,182],"regeneration":[22],"healthy":[24,136,149],"osteoporotic":[26],"conditions.":[27],"MATERIAL":[28],"AND":[29],"METHODS:":[30],"Thirty-six":[31],"10-month-old":[32],"female":[33],"rats":[35,84],"were":[36,41,65,85,109,145,166,186],"used.":[37],"Half":[38],"of":[39,58,181,204,208,229,237],"them":[40],"ovariectomized":[42],"(OVX)":[43],"fed":[45],"low-calcium":[48],"diet":[49],"to":[50,173],"induce":[51],"an":[52],"osteoporotic-like":[53],"status.":[54],"In":[55],"each":[56],"animal":[57],"both":[59],"groups,":[60],"two":[61,107],"5-mm":[62],"CSDs":[64],"treated":[66],"deproteinized":[68],"bovine":[69],"mineral":[71],"graft":[72],"particles":[73],"bilayer":[76],"collagen":[77],"membrane.":[78],"Six":[79],"OVX":[80,138,156,218],"six":[82],"control":[83],"randomly":[86,97],"euthanized":[87],"at":[88,159,201],"7,":[89],"14,":[90],"30":[92,160,202],"days.":[93],"One":[94],"defect/animal":[95],"was":[96,197,214],"chosen":[98],"for":[99],"proteomic":[100],"analysis.":[101],"Differently":[102],"expressed":[103],"proteins":[104,130,144,153,165,171],"between":[105],"the":[106,135,148,155,178,189,217,230],"groups":[108],"identified":[110,133,187],"matrix-assisted":[112],"laser":[113],"desorption":[114],"time-of-flight":[115],"mass":[116],"spectrometry":[117],"liquid":[119],"chromatography-mass":[120],"spectrometry/mass":[121],"spectrometry.":[122],"RESULTS:":[123],"At":[124,140],"7":[125],"days,":[126,142,161],"29":[127],"27":[129],"were,":[131],"respectively,":[132],"animals.":[139],"14":[141],"103":[143],"detected":[146,215],"controls":[150],"20":[152],"rats,":[157],"while":[158],"31":[162],"75":[164],"identified,":[167],"respectively.":[168],"Only":[169],"limited":[170],"known":[172],"play":[174],"role":[176],"later":[179],"stages":[180],"formation":[183,195],"maturation":[185,228],"within":[188],"animals":[190],"'proteomes.":[191],"DISCUSSION:":[192],"The":[193],"osseous":[194,231],"process":[196],"quite":[198],"immature":[199],"even":[200],"days":[203],"healing.":[205],"An":[206],"overexpression":[207],"inflammatory":[209],"stress":[211],"response":[212],"pathways":[213],"animals,":[219],"as":[220,222],"well":[221],"tendency":[224],"toward":[225],"delayed":[227],"wound":[232],"reduced/delayed":[235],"differentiation":[236],"osteoblast":[238],"cell":[239],"precursors.":[240]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-09-16T00:00:00"}