{"id":"https://openalex.org/W2500998672","doi":"https://doi.org/10.4018/978-1-60566-733-1.ch002","title":"Proteomics and Related Applications in Oral Cancer and Sj\u00f6gren's Syndrome","display_name":"Proteomics and Related Applications in Oral Cancer and Sj\u00f6gren's Syndrome","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2500998672","doi":"https://doi.org/10.4018/978-1-60566-733-1.ch002","mag":"2500998672"},"language":"en","primary_location":{"id":"doi:10.4018/978-1-60566-733-1.ch002","doi":"https://doi.org/10.4018/978-1-60566-733-1.ch002","is_oa":false,"landing_page_url":"https://doi.org/10.4018/978-1-60566-733-1.ch002","pdf_url":null,"source":{"id":"https://openalex.org/S4306463409","display_name":"IGI Global eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320424","host_organization_name":"IGI Global","host_organization_lineage":["https://openalex.org/P4310320424"],"host_organization_lineage_names":["IGI Global"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Informatics in Oral Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4214556959","display_name":"Informatics in Oral Medicine"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027299217","display_name":"Shen Hu","orcid":"https://orcid.org/0000-0001-9488-0376","observed_orcids":["https://orcid.org/0000-0001-9488-0376"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Shen Hu","raw_affiliation_strings":["University of California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5027299217"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07310376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"17","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/proteomics","display_name":"proteomics","score":0.9869999885559082},{"id":"https://openalex.org/keywords/oral-cancer","display_name":"oral cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sjogren-s-syndrome","display_name":"Sj\u00f6gren's syndrome","score":1.0},{"id":"https://openalex.org/keywords/protein-biomarkers","display_name":"protein biomarkers","score":0.8610000014305115},{"id":"https://openalex.org/keywords/mass-spectrometry","display_name":"mass spectrometry","score":0.9380000233650208},{"id":"https://openalex.org/keywords/protein-microarrays","display_name":"protein microarrays","score":1.0},{"id":"https://openalex.org/keywords/protein-expression-profiling","display_name":"protein expression profiling","score":0.8650000095367432},{"id":"https://openalex.org/keywords/disease-diagnosis","display_name":"disease diagnosis","score":0.7269999980926514},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.5559999942779541}],"concepts":[{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.9090659618377686},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5604067444801331},{"id":"https://openalex.org/C195814341","wikidata":"https://www.wikidata.org/wiki/Q494918","display_name":"Protein microarray","level":5,"score":0.5265042185783386},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5244187116622925},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.4607603847980499},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.45868420600891113},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.45057445764541626},{"id":"https://openalex.org/C2994587664","wikidata":"https://www.wikidata.org/wiki/Q494918","display_name":"Protein chip","level":2,"score":0.42687565088272095},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3587283492088318},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31353944540023804},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29124462604522705},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.14190533757209778},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10409209132194519},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07512858510017395},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.07143780589103699},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4018/978-1-60566-733-1.ch002","doi":"https://doi.org/10.4018/978-1-60566-733-1.ch002","is_oa":false,"landing_page_url":"https://doi.org/10.4018/978-1-60566-733-1.ch002","pdf_url":null,"source":{"id":"https://openalex.org/S4306463409","display_name":"IGI Global eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320424","host_organization_name":"IGI Global","host_organization_lineage":["https://openalex.org/P4310320424"],"host_organization_lineage_names":["IGI Global"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Informatics in Oral Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9074000120162964}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1570376075","https://openalex.org/W1597678601","https://openalex.org/W1965773410","https://openalex.org/W1965807926","https://openalex.org/W1970696723","https://openalex.org/W1972091672","https://openalex.org/W1976263453","https://openalex.org/W1985825509","https://openalex.org/W1987782470","https://openalex.org/W1993632446","https://openalex.org/W1998102655","https://openalex.org/W2020630954","https://openalex.org/W2023096047","https://openalex.org/W2028062404","https://openalex.org/W2039171297","https://openalex.org/W2044243127","https://openalex.org/W2045340003","https://openalex.org/W2051143564","https://openalex.org/W2051703790","https://openalex.org/W2055063265","https://openalex.org/W2056467018","https://openalex.org/W2063691016","https://openalex.org/W2067074165","https://openalex.org/W2070689312","https://openalex.org/W2078360998","https://openalex.org/W2078610240","https://openalex.org/W2082796552","https://openalex.org/W2084222255","https://openalex.org/W2097785509","https://openalex.org/W2098262034","https://openalex.org/W2099277710","https://openalex.org/W2103487488","https://openalex.org/W2108408152","https://openalex.org/W2109058963","https://openalex.org/W2111208057","https://openalex.org/W2118354284","https://openalex.org/W2119376397","https://openalex.org/W2120016245","https://openalex.org/W2123768348","https://openalex.org/W2124209533","https://openalex.org/W2126415088","https://openalex.org/W2140946052","https://openalex.org/W2142067231","https://openalex.org/W2152180036","https://openalex.org/W2156946611","https://openalex.org/W2162311651","https://openalex.org/W4236214590"],"related_works":["https://openalex.org/W2410612282","https://openalex.org/W2152149737","https://openalex.org/W2137041247","https://openalex.org/W6893527568","https://openalex.org/W4377023749","https://openalex.org/W7171393212","https://openalex.org/W2013236469","https://openalex.org/W2035467395","https://openalex.org/W2523737410","https://openalex.org/W2122772473"],"abstract_inverted_index":{"Proteomics":[0,87],"is":[1,25,61],"the":[2,16,91,110,114],"study":[3],"of":[4,8,18,40,57,66,79],"a":[5,12,26,36,97],"complete":[6],"set":[7],"proteins":[9],"present":[10],"in":[11,81],"biological":[13,47],"system":[14],"using":[15,68],"technologies":[17],"large-scale":[19],"protein":[20,41,72,103],"separation":[21],"and":[22,43,71,74,84,117],"identification.":[23],"It":[24],"powerful":[27],"approach":[28],"for":[29,35,105,122],"biomedical":[30],"research":[31,94],"because":[32],"it":[33],"aims":[34],"comprehensive,":[37],"quantitative":[38],"analysis":[39],"expression":[42],"its":[44],"changes":[45],"under":[46],"perturbations":[48],"such":[49],"as":[50],"disease":[51,93,106,115],"or":[52],"drug":[53],"treatment.":[54],"The":[55],"purpose":[56],"this":[58],"book":[59],"chapter":[60],"to":[62,75,101,108,118],"give":[63],"an":[64],"overview":[65],"proteomics":[67,80],"mass":[69],"spectrometry":[70],"microarrays":[73],"discuss":[76],"related":[77],"applications":[78],"oral":[82,92],"cancer":[83],"Sj\u00f6gren\u2019s":[85],"syndrome.":[86],"may":[88],"significantly":[89],"accelerate":[90],"by":[95],"providing":[96],"novel":[98,120],"molecular":[99,111],"technology":[100],"discover":[102],"biomarkers":[104],"diagnosis/prognosis,":[107],"elucidate":[109],"determinants":[112],"underlying":[113],"mechanism,":[116],"identify":[119],"targets":[121],"therapeutic":[123],"intervention.":[124]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-08-23T00:00:00"}