{"id":"https://openalex.org/W2500580992","doi":"https://doi.org/10.1038/ncomms15288","title":"C. elegans chromosomes connect to centrosomes by anchoring into the spindle network","display_name":"C. elegans chromosomes connect to centrosomes by anchoring into the spindle network","publication_year":2017,"publication_date":"2017-05-11","ids":{"openalex":"https://openalex.org/W2500580992","doi":"https://doi.org/10.1038/ncomms15288","mag":"2500580992","pmid":"https://pubmed.ncbi.nlm.nih.gov/28492281","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5437269"},"language":"en","primary_location":{"id":"doi:10.1038/ncomms15288","doi":"https://doi.org/10.1038/ncomms15288","is_oa":true,"landing_page_url":"https://doi.org/10.1038/ncomms15288","pdf_url":"https://www.nature.com/articles/ncomms15288.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/ncomms15288.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080403599","display_name":"Stefanie Redemann","orcid":"https://orcid.org/0000-0003-2334-7309","observed_orcids":["https://orcid.org/0000-0003-2334-7309"]},"institutions":[{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefanie Redemann","raw_affiliation_strings":["Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, 01307 Dresden, Germany","Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, Dresden, 01307, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, 01307 Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, Dresden, 01307, Germany","institution_ids":["https://openalex.org/I78650965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064631412","display_name":"Johannes Baumgart","orcid":"https://orcid.org/0000-0001-7384-5715","observed_orcids":["https://orcid.org/0000-0001-7384-5715"]},"institutions":[{"id":"https://openalex.org/I4210111875","display_name":"Max Planck Institute for the Physics of Complex Systems","ror":"https://ror.org/01bf9rw71","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210111875"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Baumgart","raw_affiliation_strings":["Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, 01187 Dresden, Germany","Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, Dresden, 01187, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7384-5715","affiliations":[{"raw_affiliation_string":"Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, 01187 Dresden, Germany","institution_ids":["https://openalex.org/I4210111875"]},{"raw_affiliation_string":"Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, Dresden, 01187, Germany","institution_ids":["https://openalex.org/I4210111875"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072697451","display_name":"Norbert Lindow","orcid":"https://orcid.org/0000-0001-5143-2573","observed_orcids":["https://orcid.org/0000-0001-5143-2573"]},"institutions":[{"id":"https://openalex.org/I195893171","display_name":"Zuse Institute Berlin","ror":"https://ror.org/02eva5865","country_code":"DE","type":"facility","lineage":["https://openalex.org/I195893171"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Norbert Lindow","raw_affiliation_strings":["Zuse Institute Berlin, Takustra\u00dfe 7, 14195 Berlin, Germany","Zuse Institute Berlin, Takustra\u00dfe 7, Berlin, 14195, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zuse Institute Berlin, Takustra\u00dfe 7, 14195 Berlin, Germany","institution_ids":["https://openalex.org/I195893171"]},{"raw_affiliation_string":"Zuse Institute Berlin, Takustra\u00dfe 7, Berlin, 14195, Germany","institution_ids":["https://openalex.org/I195893171"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068281815","display_name":"Michael Shelley","orcid":"https://orcid.org/0000-0002-4835-0339","observed_orcids":["https://orcid.org/0000-0002-4835-0339"]},"institutions":[{"id":"https://openalex.org/I36672615","display_name":"Courant Institute of Mathematical Sciences","ror":"https://ror.org/037tm7f56","country_code":"US","type":"education","lineage":["https://openalex.org/I36672615","https://openalex.org/I57206974"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael Shelley","raw_affiliation_strings":["The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA","The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, 10012, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]},{"raw_affiliation_string":"The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, 10012, New York, USA","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006888147","display_name":"Ehssan Nazockdast","orcid":"https://orcid.org/0000-0002-3811-0067","observed_orcids":["https://orcid.org/0000-0002-3811-0067"]},"institutions":[{"id":"https://openalex.org/I36672615","display_name":"Courant Institute of Mathematical Sciences","ror":"https://ror.org/037tm7f56","country_code":"US","type":"education","lineage":["https://openalex.org/I36672615","https://openalex.org/I57206974"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ehssan Nazockdast","raw_affiliation_strings":["The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA","The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, 10012, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]},{"raw_affiliation_string":"The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, 10012, New York, USA","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084614966","display_name":"Andrea Kratz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I195893171","display_name":"Zuse Institute Berlin","ror":"https://ror.org/02eva5865","country_code":"DE","type":"facility","lineage":["https://openalex.org/I195893171"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andrea Kratz","raw_affiliation_strings":["Zuse Institute Berlin, Takustra\u00dfe 7, 14195 Berlin, Germany","Zuse Institute Berlin, Takustra\u00dfe 7, Berlin, 14195, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zuse Institute Berlin, Takustra\u00dfe 7, 14195 Berlin, Germany","institution_ids":["https://openalex.org/I195893171"]},{"raw_affiliation_string":"Zuse Institute Berlin, Takustra\u00dfe 7, Berlin, 14195, Germany","institution_ids":["https://openalex.org/I195893171"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109147899","display_name":"Steffen Prohaska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I195893171","display_name":"Zuse Institute Berlin","ror":"https://ror.org/02eva5865","country_code":"DE","type":"facility","lineage":["https://openalex.org/I195893171"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Prohaska","raw_affiliation_strings":["Zuse Institute Berlin, Takustra\u00dfe 7, 14195 Berlin, Germany","Zuse Institute Berlin, Takustra\u00dfe 7, Berlin, 14195, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zuse Institute Berlin, Takustra\u00dfe 7, 14195 Berlin, Germany","institution_ids":["https://openalex.org/I195893171"]},{"raw_affiliation_string":"Zuse Institute Berlin, Takustra\u00dfe 7, Berlin, 14195, Germany","institution_ids":["https://openalex.org/I195893171"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078337827","display_name":"Jan Brugu\u00e9s A","orcid":"https://orcid.org/0000-0002-6731-4130","observed_orcids":["https://orcid.org/0000-0002-6731-4130"]},"institutions":[{"id":"https://openalex.org/I4210111875","display_name":"Max Planck Institute for the Physics of Complex Systems","ror":"https://ror.org/01bf9rw71","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210111875"]},{"id":"https://openalex.org/I4210148197","display_name":"Center for Systems Biology Dresden","ror":"https://ror.org/05hrn3e05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210111875","https://openalex.org/I4210148197","https://openalex.org/I4210159854","https://openalex.org/I78650965"]},{"id":"https://openalex.org/I4210159854","display_name":"Max Planck Institute of Molecular Cell Biology and Genetics","ror":"https://ror.org/05b8d3w18","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210159854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan Brugu\u00e9s","raw_affiliation_strings":["Centre for Systems Biology Dresden, Pfotenhauerstr. 108, 01307 Dresden, Germany","Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, 01187 Dresden, Germany","Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstra\u00dfe 108, 01307 Dresden, Germany","Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, Dresden, 01187, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Systems Biology Dresden, Pfotenhauerstr. 108, 01307 Dresden, Germany","institution_ids":["https://openalex.org/I4210148197"]},{"raw_affiliation_string":"Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, 01187 Dresden, Germany","institution_ids":["https://openalex.org/I4210111875"]},{"raw_affiliation_string":"Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstra\u00dfe 108, 01307 Dresden, Germany","institution_ids":["https://openalex.org/I4210159854"]},{"raw_affiliation_string":"Max Planck Institute for the Physics of Complex Systems, N\u00f6thnitzer Stra\u00dfe 38, Dresden, 01187, Germany","institution_ids":["https://openalex.org/I4210111875"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088549673","display_name":"Sebastian F\u00fcrthauer","orcid":"https://orcid.org/0000-0001-9581-5963","observed_orcids":["https://orcid.org/0000-0001-9581-5963"]},"institutions":[{"id":"https://openalex.org/I36672615","display_name":"Courant Institute of Mathematical Sciences","ror":"https://ror.org/037tm7f56","country_code":"US","type":"education","lineage":["https://openalex.org/I36672615","https://openalex.org/I57206974"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sebastian F\u00fcrthauer","raw_affiliation_strings":["The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA","The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, 10012, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]},{"raw_affiliation_string":"The Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, 10012, New York, USA","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006669393","display_name":"Thomas M\u00fcller\u2010Reichert","orcid":"https://orcid.org/0000-0003-0203-1436","observed_orcids":["https://orcid.org/0000-0003-0203-1436"]},"institutions":[{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas M\u00fcller-Reichert","raw_affiliation_strings":["Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, 01307 Dresden, Germany","Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, Dresden, 01307, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, 01307 Dresden, Germany","institution_ids":["https://openalex.org/I78650965"]},{"raw_affiliation_string":"Technische Universit\u00e4t Dresden, Experimental Center, Medical Faculty Carl Gustav Carus, Fiedlerstra\u00dfe 42, Dresden, 01307, Germany","institution_ids":["https://openalex.org/I78650965"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5068281815"],"corresponding_institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"],"apc_list":{"value":6990,"currency":"USD","value_usd":6990},"apc_paid":{"value":6990,"currency":"USD","value_usd":6990},"fwci":9.1978,"has_fulltext":true,"cited_by_count":136,"citation_normalized_percentile":{"value":0.98781008,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"8","issue":"1","first_page":"15288","last_page":"15288"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitotic-spindle","display_name":"mitotic spindle","score":0.8379999995231628},{"id":"https://openalex.org/keywords/centrosome","display_name":"centrosome","score":0.7689999938011169},{"id":"https://openalex.org/keywords/chromosome-segregation","display_name":"chromosome segregation","score":0.5730000138282776},{"id":"https://openalex.org/keywords/kinetochore-microtubules","display_name":"kinetochore microtubules","score":0.9570000171661377},{"id":"https://openalex.org/keywords/astral-microtubules","display_name":"astral microtubules","score":0.9800000190734863},{"id":"https://openalex.org/keywords/spindle-microtubules","display_name":"spindle microtubules","score":0.9139999747276306},{"id":"https://openalex.org/keywords/microtubule-nucleation","display_name":"microtubule nucleation","score":0.9039999842643738},{"id":"https://openalex.org/keywords/microtubule-depolymerization","display_name":"microtubule depolymerization","score":0.9229999780654907},{"id":"https://openalex.org/keywords/caenorhabditis-elegans-embryo","display_name":"Caenorhabditis elegans embryo","score":0.828000009059906}],"concepts":[{"id":"https://openalex.org/C10447061","wikidata":"https://www.wikidata.org/wiki/Q190769","display_name":"Centrosome","level":4,"score":0.8831872344017029},{"id":"https://openalex.org/C47432576","wikidata":"https://www.wikidata.org/wiki/Q918594","display_name":"Spindle apparatus","level":4,"score":0.7408785820007324},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6933308243751526},{"id":"https://openalex.org/C9565192","wikidata":"https://www.wikidata.org/wiki/Q2868390","display_name":"Astral microtubules","level":5,"score":0.6902808547019958},{"id":"https://openalex.org/C192838845","wikidata":"https://www.wikidata.org/wiki/Q908912","display_name":"Kinetochore","level":4,"score":0.6822109818458557},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.6225538849830627},{"id":"https://openalex.org/C70547292","wikidata":"https://www.wikidata.org/wiki/Q12386518","display_name":"Spindle pole body","level":5,"score":0.6029466390609741},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.5730515718460083},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.53904789686203},{"id":"https://openalex.org/C2778354886","wikidata":"https://www.wikidata.org/wiki/Q5113927","display_name":"Chromosome segregation","level":4,"score":0.5051072239875793},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.2300121784210205},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19440513849258423},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.17905539274215698},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.1491348147392273},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.08464416861534119},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.05025091767311096}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002875","descriptor_name":"Chromosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008870","descriptor_name":"Microtubules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008941","descriptor_name":"Spindle Apparatus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D017173","descriptor_name":"Caenorhabditis elegans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018385","descriptor_name":"Centrosome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018386","descriptor_name":"Kinetochores","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":12,"locations":[{"id":"doi:10.1038/ncomms15288","doi":"https://doi.org/10.1038/ncomms15288","is_oa":true,"landing_page_url":"https://doi.org/10.1038/ncomms15288","pdf_url":"https://www.nature.com/articles/ncomms15288.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"doi:10.1101/060855","doi":"https://doi.org/10.1101/060855","is_oa":true,"landing_page_url":"https://doi.org/10.1101/060855","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2016/12/10/060855.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:europepmc.org:4305339","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC5437269","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5437269","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5437269","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmid:28492281","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28492281","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_ncomms15288","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/ncomms15288","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:046e8d07808d493ab9b645788aa2c7ff","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/046e8d07808d493ab9b645788aa2c7ff","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)","raw_type":"article"},{"id":"pmh:oai:escidoc.org:escidoc:2471035","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-002D-C33D-2","pdf_url":null,"source":{"id":"https://openalex.org/S7407052962","display_name":"Max Planck Digital Library","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210088280","host_organization_name":"Max Planck Digital Library","host_organization_lineage":["https://openalex.org/I4210088280"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:escidoc.org:escidoc:2615920","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/21.11116/0000-0001-9E5C-7","pdf_url":null,"source":{"id":"https://openalex.org/S7407052962","display_name":"Max Planck Digital Library","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210088280","host_organization_name":"Max Planck Digital Library","host_organization_lineage":["https://openalex.org/I4210088280"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/other"},{"id":"pmh:oai:pure.mpg.de:item_2471035","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11858/00-001M-0000-002D-C33D-2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_2615920","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/21.11116/0000-0001-9E5C-7","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/other"},{"id":"pmh:oai:pure.mpg.de:item_2642454","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/21.11116/0000-0002-8B88-8","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature communications","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/ncomms15288","doi":"https://doi.org/10.1038/ncomms15288","is_oa":true,"landing_page_url":"https://doi.org/10.1038/ncomms15288","pdf_url":"https://www.nature.com/articles/ncomms15288.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/15","score":0.4000000059604645,"display_name":"Life on land"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1297368160","display_name":null,"funder_award_id":"DMS-1463962","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3527005925","display_name":null,"funder_award_id":"MU 1423/8\u20101","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3732288533","display_name":"Understanding mitotic spindle positioning by integrated  modeling and experiment","funder_award_id":"R01GM104976","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4514852157","display_name":"Collaborative Research: FRG: Understanding and Controlling Active Fluids through Modeling, Simulation, and Experiment","funder_award_id":"1463962","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320323644","display_name":"S\u00e4chsisches Staatsministerium f\u00fcr Wissenschaft und Kunst","ror":"https://ror.org/05wnef833"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2500580992.pdf","grobid_xml":"https://content.openalex.org/works/W2500580992.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W574078859","https://openalex.org/W1486450190","https://openalex.org/W1552632109","https://openalex.org/W1587742798","https://openalex.org/W1595209923","https://openalex.org/W1944127002","https://openalex.org/W1965404941","https://openalex.org/W1968766290","https://openalex.org/W1975227291","https://openalex.org/W1976311440","https://openalex.org/W1979771881","https://openalex.org/W1982613135","https://openalex.org/W1986466512","https://openalex.org/W1988573682","https://openalex.org/W1992692440","https://openalex.org/W1993698875","https://openalex.org/W2008807242","https://openalex.org/W2019724567","https://openalex.org/W2021944123","https://openalex.org/W2022780485","https://openalex.org/W2022923913","https://openalex.org/W2029101220","https://openalex.org/W2029887363","https://openalex.org/W2030160368","https://openalex.org/W2030967170","https://openalex.org/W2033289972","https://openalex.org/W2036742579","https://openalex.org/W2042351695","https://openalex.org/W2042629182","https://openalex.org/W2043410014","https://openalex.org/W2043415140","https://openalex.org/W2049526129","https://openalex.org/W2060004518","https://openalex.org/W2079137734","https://openalex.org/W2087130779","https://openalex.org/W2087311605","https://openalex.org/W2095579053","https://openalex.org/W2097664711","https://openalex.org/W2099337089","https://openalex.org/W2112378641","https://openalex.org/W2117130719","https://openalex.org/W2117279934","https://openalex.org/W2120125134","https://openalex.org/W2120157563","https://openalex.org/W2121182271","https://openalex.org/W2121903259","https://openalex.org/W2123022596","https://openalex.org/W2131113110","https://openalex.org/W2131282221","https://openalex.org/W2132705366","https://openalex.org/W2137794042","https://openalex.org/W2142226910","https://openalex.org/W2145131593","https://openalex.org/W2150167921","https://openalex.org/W2155923449","https://openalex.org/W2157420503","https://openalex.org/W2158918551","https://openalex.org/W2161659315","https://openalex.org/W2164962038","https://openalex.org/W2167960449","https://openalex.org/W2290367328","https://openalex.org/W2335060536","https://openalex.org/W2399690657","https://openalex.org/W2416985224","https://openalex.org/W4301352482"],"related_works":["https://openalex.org/W1979771881","https://openalex.org/W7095096989","https://openalex.org/W7034416350","https://openalex.org/W2006470383","https://openalex.org/W4287837113","https://openalex.org/W7015287833","https://openalex.org/W2962882580","https://openalex.org/W2143987043","https://openalex.org/W2021519480","https://openalex.org/W2100356480"],"abstract_inverted_index":{"The":[0],"mitotic":[1,20],"spindle":[2,48,134],"ensures":[3],"the":[4,12,78,89,112,120,132],"faithful":[5],"segregation":[6],"of":[7,18,62,97,104],"chromosomes.":[8],"Here":[9],"we":[10,80,100],"combine":[11],"first":[13],"large-scale":[14],"serial":[15],"electron":[16],"tomography":[17],"whole":[19],"spindles":[21],"in":[22,34],"early":[23],"C.":[24],"elegans":[25],"embryos":[26],"with":[27],"live-cell":[28],"imaging":[29],"to":[30,55,88],"reconstruct":[31],"all":[32],"microtubules":[33,52,74],"3D":[35],"and":[36,40,58,69,109,124,136,145],"identify":[37],"their":[38,56],"plus-":[39],"minus-ends.":[41],"We":[42],"classify":[43],"them":[44],"as":[45],"kinetochore":[46],"(KMTs),":[47],"(SMTs)":[49],"or":[50],"astral":[51],"(AMTs)":[53],"according":[54],"positions,":[57],"quantify":[59],"distinct":[60],"properties":[61],"each":[63],"class.":[64],"While":[65],"our":[66,116],"light":[67],"microscopy":[68],"mutant":[70],"studies":[71],"show":[72,118],"that":[73,102,119,137],"are":[75,143],"nucleated":[76],"from":[77,111],"centrosomes,":[79],"find":[81],"only":[82],"a":[83],"few":[84,144],"KMTs":[85,105,142],"directly":[86],"connected":[87],"centrosomes.":[90],"Indeed,":[91],"by":[92,128],"quantitatively":[93],"analysing":[94],"several":[95],"models":[96],"microtubule":[98],"growth,":[99],"conclude":[101],"minus-ends":[103],"have":[106],"selectively":[107],"detached":[108],"depolymerized":[110],"centrosome.":[113],"In":[114],"toto,":[115],"results":[117],"connection":[121],"between":[122],"centrosomes":[123],"chromosomes":[125],"is":[126],"mediated":[127],"an":[129],"anchoring":[130],"into":[131],"entire":[133],"network":[135],"any":[138],"direct":[139],"connections":[140],"through":[141],"likely":[146],"very":[147],"transient.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":18},{"year":2018,"cited_by_count":22},{"year":2017,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-08-23T00:00:00"}
