{"id":"https://openalex.org/W2500553418","doi":"https://doi.org/10.1038/ijo.2016.125","title":"The impact of inflammation on the obesity paradox in coronary heart disease","display_name":"The impact of inflammation on the obesity paradox in coronary heart disease","publication_year":2016,"publication_date":"2016-07-25","ids":{"openalex":"https://openalex.org/W2500553418","doi":"https://doi.org/10.1038/ijo.2016.125","mag":"2500553418","pmid":"https://pubmed.ncbi.nlm.nih.gov/27453423"},"language":"en","primary_location":{"id":"doi:10.1038/ijo.2016.125","doi":"https://doi.org/10.1038/ijo.2016.125","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ijo.2016.125","pdf_url":null,"source":{"id":"https://openalex.org/S103428141","display_name":"International Journal of Obesity","issn_l":"0307-0565","issn":["0307-0565","1476-5497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Obesity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109035677","display_name":"A. De Schutter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]},{"id":"https://openalex.org/I4210108700","display_name":"Cleveland Clinic Florida","ror":"https://ror.org/0155k7414","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4210108700"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"A De Schutter","raw_affiliation_strings":["Department of Medicine, Cleveland Clinic Florida, Weston, FL, USA","John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Cleveland Clinic Florida, Weston, FL, USA","institution_ids":["https://openalex.org/I4210108700"]},{"raw_affiliation_string":"John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I2799767083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087134272","display_name":"Sergey M. Kachur","orcid":"https://orcid.org/0000-0002-8607-7169","observed_orcids":["https://orcid.org/0000-0002-8607-7169"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Kachur","raw_affiliation_strings":["Ocala Regional Medical Center, Ocala, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ocala Regional Medical Center, Ocala, FL, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059582018","display_name":"Carl J. Lavie","orcid":"https://orcid.org/0000-0003-3906-1911","observed_orcids":["https://orcid.org/0000-0003-3906-1911"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["AU","US"],"is_corresponding":true,"raw_author_name":"C J Lavie","raw_affiliation_strings":["John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I2799767083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027557121","display_name":"Raja S. Boddepalli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108700","display_name":"Cleveland Clinic Florida","ror":"https://ror.org/0155k7414","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4210108700"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R S Boddepalli","raw_affiliation_strings":["Department of Medicine, Cleveland Clinic Florida, Weston, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Cleveland Clinic Florida, Weston, FL, USA","institution_ids":["https://openalex.org/I4210108700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013610015","display_name":"Dharti Patel","orcid":"https://orcid.org/0000-0002-1028-6589","observed_orcids":["https://orcid.org/0000-0002-1028-6589"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I2799342587","display_name":"Erlanger Health System","ror":"https://ror.org/04sz0rs34","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799342587"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"D A Patel","raw_affiliation_strings":["Division of Cardiovascular Medicine, UT Erlanger Cardiology - Erlanger Health System and University of Tennessee, College of Medicine, Chattanooga, TN, USA","John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, UT Erlanger Cardiology - Erlanger Health System and University of Tennessee, College of Medicine, Chattanooga, TN, USA","institution_ids":["https://openalex.org/I2799342587"]},{"raw_affiliation_string":"John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I2799767083"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022846993","display_name":"Richard V. Milani","orcid":"https://orcid.org/0000-0002-6094-8253","observed_orcids":["https://orcid.org/0000-0002-6094-8253"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I2799767083","display_name":"Ochsner Medical Center","ror":"https://ror.org/0290qyp66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336053918","https://openalex.org/I2799767083"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"R V Milani","raw_affiliation_strings":["John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"John Ochsner Heart and Vascular Institute, Ochsner Clinical School - The University of Queensland School of Medicine, New Orleans, LA, USA","institution_ids":["https://openalex.org/I165143802","https://openalex.org/I2799767083"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5059582018"],"corresponding_institution_ids":["https://openalex.org/I165143802","https://openalex.org/I2799767083"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":2.6837,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.9148088,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"40","issue":"11","first_page":"1730","last_page":"1735"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.20679999887943268,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.20679999887943268,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12979","display_name":"Cardiovascular Disease and Adiposity","score":0.1770000010728836,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.13609999418258667,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obesity-paradox","display_name":"obesity paradox","score":1.0},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9860000014305115},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8309999704360962},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9959999918937683},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.9049999713897705},{"id":"https://openalex.org/keywords/body-fat","display_name":"fat mass","score":0.8970000147819519},{"id":"https://openalex.org/keywords/lean-mass-index","display_name":"lean mass index","score":0.984000027179718},{"id":"https://openalex.org/keywords/body-composition","display_name":"body composition","score":0.9860000014305115},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.7490000128746033},{"id":"https://openalex.org/keywords/cardiac-rehabilitation","display_name":"cardiac rehabilitation","score":0.9390000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7157665491104126},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6655223965644836},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.6004398465156555},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5841875672340393},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5838261246681213},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.557898223400116},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43106675148010254},{"id":"https://openalex.org/C2781223611","wikidata":"https://www.wikidata.org/wiki/Q357496","display_name":"Obesity paradox","level":4,"score":0.41902098059654236},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.32869040966033936}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015992","descriptor_name":"Body Mass Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/ijo.2016.125","doi":"https://doi.org/10.1038/ijo.2016.125","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ijo.2016.125","pdf_url":null,"source":{"id":"https://openalex.org/S103428141","display_name":"International Journal of Obesity","issn_l":"0307-0565","issn":["0307-0565","1476-5497"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Obesity","raw_type":"journal-article"},{"id":"pmid:27453423","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27453423","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of obesity (2005)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W121579194","https://openalex.org/W130193209","https://openalex.org/W174870447","https://openalex.org/W1598667444","https://openalex.org/W1929626127","https://openalex.org/W1963872354","https://openalex.org/W1964310251","https://openalex.org/W1968836134","https://openalex.org/W1977031042","https://openalex.org/W1978059607","https://openalex.org/W1995765769","https://openalex.org/W1998415578","https://openalex.org/W1999264494","https://openalex.org/W2000601564","https://openalex.org/W2006566799","https://openalex.org/W2007610181","https://openalex.org/W2009200981","https://openalex.org/W2010371883","https://openalex.org/W2012689879","https://openalex.org/W2014916573","https://openalex.org/W2024617256","https://openalex.org/W2025257982","https://openalex.org/W2025888270","https://openalex.org/W2029018065","https://openalex.org/W2034349672","https://openalex.org/W2051865087","https://openalex.org/W2057369974","https://openalex.org/W2058709767","https://openalex.org/W2063607755","https://openalex.org/W2064336568","https://openalex.org/W2066890285","https://openalex.org/W2067831366","https://openalex.org/W2068304609","https://openalex.org/W2072005929","https://openalex.org/W2075998179","https://openalex.org/W2084694910","https://openalex.org/W2087851876","https://openalex.org/W2094783811","https://openalex.org/W2102321386","https://openalex.org/W2106918180","https://openalex.org/W2107865201","https://openalex.org/W2125891558","https://openalex.org/W2128537858","https://openalex.org/W2134063325","https://openalex.org/W2138750223","https://openalex.org/W2147181044","https://openalex.org/W2151594453","https://openalex.org/W2152034819","https://openalex.org/W2152068779","https://openalex.org/W2159654120","https://openalex.org/W2166370133","https://openalex.org/W2169166675","https://openalex.org/W2169552837","https://openalex.org/W2224335343"],"related_works":["https://openalex.org/W154162277","https://openalex.org/W7153040209","https://openalex.org/W4416978243","https://openalex.org/W2169166675","https://openalex.org/W2488729929","https://openalex.org/W2943483386","https://openalex.org/W1964310251","https://openalex.org/W2093421071","https://openalex.org/W4403915739","https://openalex.org/W2565165051"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-08-23T00:00:00"}