{"id":"https://openalex.org/W2499265357","doi":"https://doi.org/10.1016/b978-0-12-396521-9.00003-6","title":"Natural Product Chemistry and Cancer Drug Discovery","display_name":"Natural Product Chemistry and Cancer Drug Discovery","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2499265357","doi":"https://doi.org/10.1016/b978-0-12-396521-9.00003-6","mag":"2499265357"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-396521-9.00003-6","doi":"https://doi.org/10.1016/b978-0-12-396521-9.00003-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-396521-9.00003-6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Drug Design and Discovery","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4300070702","display_name":"Cancer Drug Design and Discovery"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088980863","display_name":"Donna M. Huryn","orcid":"https://orcid.org/0000-0001-5542-4968","observed_orcids":["https://orcid.org/0000-0001-5542-4968"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donna M. Huryn","raw_affiliation_strings":["Center for Chemical Methodologies and Library Development (UPCMLD), University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Chemical Methodologies and Library Development (UPCMLD), University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018024103","display_name":"Peter Wipf","orcid":"https://orcid.org/0000-0001-7693-5863","observed_orcids":["https://orcid.org/0000-0001-7693-5863"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Wipf","raw_affiliation_strings":["Center for Chemical Methodologies and Library Development (UPCMLD), University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Chemical Methodologies and Library Development (UPCMLD), University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":null,"apc_paid":null,"fwci":1.6775,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.85585269,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"91","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.4147999882698059,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.4147999882698059,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.10199999809265137,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.0925000011920929,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-products","display_name":"natural products","score":0.8999999761581421},{"id":"https://openalex.org/keywords/anticancer-drug-discovery","display_name":"anticancer drug discovery","score":0.8840000033378601},{"id":"https://openalex.org/keywords/enzyme-inhibitors","display_name":"enzyme inhibitors","score":0.7630000114440918},{"id":"https://openalex.org/keywords/signaling-pathway-inhibitors","display_name":"signaling pathway inhibitors","score":0.8389999866485596},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.5889999866485596},{"id":"https://openalex.org/keywords/diversity-oriented-synthesis","display_name":"diversity-oriented synthesis","score":0.7459999918937683},{"id":"https://openalex.org/keywords/vascularization","display_name":"vascularization","score":0.4779999852180481},{"id":"https://openalex.org/keywords/tissue-adhesion","display_name":"tissue adhesion","score":0.7879999876022339},{"id":"https://openalex.org/keywords/tumor-penetration","display_name":"tumor penetration","score":0.6000000238418579},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C2779396153","wikidata":"https://www.wikidata.org/wiki/Q901227","display_name":"Natural product","level":2,"score":0.7990294694900513},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.5203587412834167},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5076843500137329},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42921513319015503},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42744386196136475},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.42252117395401},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4069855809211731},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3717462718486786},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3700839877128601},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.32861045002937317},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3139718770980835},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1430288851261139},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06801727414131165}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-12-396521-9.00003-6","doi":"https://doi.org/10.1016/b978-0-12-396521-9.00003-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-396521-9.00003-6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Drug Design and Discovery","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":196,"referenced_works":["https://openalex.org/W132219144","https://openalex.org/W170336416","https://openalex.org/W1541040185","https://openalex.org/W1549178276","https://openalex.org/W1559855960","https://openalex.org/W1574399898","https://openalex.org/W1575977535","https://openalex.org/W1594148627","https://openalex.org/W1661993026","https://openalex.org/W1855853533","https://openalex.org/W1965669201","https://openalex.org/W1966404502","https://openalex.org/W1968626776","https://openalex.org/W1968903040","https://openalex.org/W1968904517","https://openalex.org/W1969843553","https://openalex.org/W1970138930","https://openalex.org/W1970177198","https://openalex.org/W1970798080","https://openalex.org/W1972571586","https://openalex.org/W1973447396","https://openalex.org/W1974320358","https://openalex.org/W1975604260","https://openalex.org/W1977166636","https://openalex.org/W1977229721","https://openalex.org/W1978514556","https://openalex.org/W1979436080","https://openalex.org/W1979576209","https://openalex.org/W1983388930","https://openalex.org/W1983772374","https://openalex.org/W1984050613","https://openalex.org/W1984807054","https://openalex.org/W1985858069","https://openalex.org/W1988329373","https://openalex.org/W1988916934","https://openalex.org/W1990368870","https://openalex.org/W1992084711","https://openalex.org/W1992241408","https://openalex.org/W1992716708","https://openalex.org/W1993091819","https://openalex.org/W1994109490","https://openalex.org/W1994673341","https://openalex.org/W1995560549","https://openalex.org/W1999244585","https://openalex.org/W1999995926","https://openalex.org/W2000690012","https://openalex.org/W2000779382","https://openalex.org/W2003062238","https://openalex.org/W2004777236","https://openalex.org/W2004783782","https://openalex.org/W2007092325","https://openalex.org/W2008336243","https://openalex.org/W2008599415","https://openalex.org/W2009087723","https://openalex.org/W2009944379","https://openalex.org/W2013310372","https://openalex.org/W2014014132","https://openalex.org/W2014242667","https://openalex.org/W2014573616","https://openalex.org/W2014789297","https://openalex.org/W2014922787","https://openalex.org/W2015803938","https://openalex.org/W2015900502","https://openalex.org/W2016552601","https://openalex.org/W2017167372","https://openalex.org/W2017434303","https://openalex.org/W2017553996","https://openalex.org/W2018185888","https://openalex.org/W2018906142","https://openalex.org/W2022009220","https://openalex.org/W2022531767","https://openalex.org/W2022541271","https://openalex.org/W2026709688","https://openalex.org/W2028321505","https://openalex.org/W2029505994","https://openalex.org/W2029649301","https://openalex.org/W2030177226","https://openalex.org/W2033702956","https://openalex.org/W2034765079","https://openalex.org/W2037956573","https://openalex.org/W2039338567","https://openalex.org/W2041769918","https://openalex.org/W2042699875","https://openalex.org/W2043873747","https://openalex.org/W2045410853","https://openalex.org/W2046528835","https://openalex.org/W2046794494","https://openalex.org/W2047169010","https://openalex.org/W2047488136","https://openalex.org/W2048226711","https://openalex.org/W2048452699","https://openalex.org/W2050420673","https://openalex.org/W2051292102","https://openalex.org/W2051905420","https://openalex.org/W2052767109","https://openalex.org/W2052930708","https://openalex.org/W2055785743","https://openalex.org/W2056238632","https://openalex.org/W2056667035","https://openalex.org/W2058641375","https://openalex.org/W2059140374","https://openalex.org/W2059716720","https://openalex.org/W2060802613","https://openalex.org/W2061006137","https://openalex.org/W2061198246","https://openalex.org/W2063013379","https://openalex.org/W2063202715","https://openalex.org/W2063315796","https://openalex.org/W2064767777","https://openalex.org/W2065076407","https://openalex.org/W2066022960","https://openalex.org/W2066798929","https://openalex.org/W2067071751","https://openalex.org/W2068650460","https://openalex.org/W2070534090","https://openalex.org/W2071535939","https://openalex.org/W2072359587","https://openalex.org/W2073898802","https://openalex.org/W2074521790","https://openalex.org/W2074695805","https://openalex.org/W2075333946","https://openalex.org/W2077248326","https://openalex.org/W2078880911","https://openalex.org/W2080758225","https://openalex.org/W2082390299","https://openalex.org/W2082565204","https://openalex.org/W2086353181","https://openalex.org/W2087259918","https://openalex.org/W2087925816","https://openalex.org/W2087968322","https://openalex.org/W2089011659","https://openalex.org/W2089771537","https://openalex.org/W2090745860","https://openalex.org/W2094477446","https://openalex.org/W2094708689","https://openalex.org/W2096616470","https://openalex.org/W2096955693","https://openalex.org/W2097978589","https://openalex.org/W2100092765","https://openalex.org/W2100742298","https://openalex.org/W2102602516","https://openalex.org/W2103498669","https://openalex.org/W2104903083","https://openalex.org/W2106447461","https://openalex.org/W2110891275","https://openalex.org/W2111685942","https://openalex.org/W2114340483","https://openalex.org/W2114892806","https://openalex.org/W2119845123","https://openalex.org/W2121832826","https://openalex.org/W2123056940","https://openalex.org/W2124038924","https://openalex.org/W2125591574","https://openalex.org/W2126512953","https://openalex.org/W2127756768","https://openalex.org/W2128272164","https://openalex.org/W2134882450","https://openalex.org/W2134979720","https://openalex.org/W2139306838","https://openalex.org/W2143716285","https://openalex.org/W2145998504","https://openalex.org/W2146712472","https://openalex.org/W2147051864","https://openalex.org/W2150969390","https://openalex.org/W2154587590","https://openalex.org/W2155350255","https://openalex.org/W2156565205","https://openalex.org/W2159297343","https://openalex.org/W2160711371","https://openalex.org/W2162331245","https://openalex.org/W2163685688","https://openalex.org/W2165993401","https://openalex.org/W2316050582","https://openalex.org/W2316999855","https://openalex.org/W2326472068","https://openalex.org/W2469194024","https://openalex.org/W2487323885","https://openalex.org/W2487729568","https://openalex.org/W2495813255","https://openalex.org/W2550857644","https://openalex.org/W2620176919","https://openalex.org/W2949332675","https://openalex.org/W2950225192","https://openalex.org/W2951139381","https://openalex.org/W2951507975","https://openalex.org/W2951633595","https://openalex.org/W2951859542","https://openalex.org/W2952223245","https://openalex.org/W2952944874","https://openalex.org/W2990983553","https://openalex.org/W4240220710","https://openalex.org/W4241532757","https://openalex.org/W4285719527","https://openalex.org/W6682957436","https://openalex.org/W6729315230","https://openalex.org/W6770564467"],"related_works":["https://openalex.org/W3023275690","https://openalex.org/W4311051500","https://openalex.org/W7223325784","https://openalex.org/W2112123578","https://openalex.org/W2068674968","https://openalex.org/W3119787068","https://openalex.org/W2041163647","https://openalex.org/W2041055204","https://openalex.org/W1999673565","https://openalex.org/W4309089963"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-08-23T00:00:00"}
