{"id":"https://openalex.org/W2498124372","doi":"https://doi.org/10.1007/978-1-4419-0717-2_3","title":"Type I Insulin-Like Growth Factor Receptor","display_name":"Type I Insulin-Like Growth Factor Receptor","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2498124372","doi":"https://doi.org/10.1007/978-1-4419-0717-2_3","mag":"2498124372"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4419-0717-2_3","doi":"https://doi.org/10.1007/978-1-4419-0717-2_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4419-0717-2_3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Therapeutic Targets","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2501434749","display_name":"Cancer Therapeutic Targets"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033966004","display_name":"Douglas Yee","orcid":"https://orcid.org/0000-0002-3387-4009","observed_orcids":["https://orcid.org/0000-0002-3387-4009"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Douglas Yee","raw_affiliation_strings":["Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5033966004"],"corresponding_institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00554529,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"823","last_page":"829"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12287","display_name":"Fibroblast Growth Factor Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/igf-1-receptor","display_name":"IGF-1 receptor","score":0.9800000190734863},{"id":"https://openalex.org/keywords/receptor-tyrosine-kinases","display_name":"receptor tyrosine kinase","score":0.8399999737739563},{"id":"https://openalex.org/keywords/igf-system","display_name":"IGF system","score":0.6779999732971191},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.9369999766349792},{"id":"https://openalex.org/keywords/receptor-signaling","display_name":"receptor signaling","score":0.6200000047683716},{"id":"https://openalex.org/keywords/igf1r-inhibitors","display_name":"IGF1R inhibitors","score":0.8650000095367432},{"id":"https://openalex.org/keywords/drug-development","display_name":"drug development","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C2780689927","wikidata":"https://www.wikidata.org/wiki/Q24766801","display_name":"Insulin-like growth factor","level":4,"score":0.5567309856414795},{"id":"https://openalex.org/C2781039887","wikidata":"https://www.wikidata.org/wiki/Q1391724","display_name":"Factor (programming language)","level":2,"score":0.5084306597709656},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.33778801560401917},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.31664448976516724},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30820366740226746},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2703118324279785},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2533072233200073},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2256850004196167},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1722402274608612},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.04015573859214783}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4419-0717-2_3","doi":"https://doi.org/10.1007/978-1-4419-0717-2_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4419-0717-2_3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Therapeutic Targets","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1534439131","https://openalex.org/W1583743328","https://openalex.org/W1824970382","https://openalex.org/W1853387493","https://openalex.org/W1919421236","https://openalex.org/W1971293891","https://openalex.org/W1973713507","https://openalex.org/W1989891233","https://openalex.org/W1997171350","https://openalex.org/W1999030960","https://openalex.org/W2031253131","https://openalex.org/W2035751072","https://openalex.org/W2040104879","https://openalex.org/W2054711858","https://openalex.org/W2062565310","https://openalex.org/W2079894826","https://openalex.org/W2098095015","https://openalex.org/W2101784016","https://openalex.org/W2104259296","https://openalex.org/W2104339838","https://openalex.org/W2106321700","https://openalex.org/W2110600280","https://openalex.org/W2110843592","https://openalex.org/W2111843196","https://openalex.org/W2112474467","https://openalex.org/W2118779298","https://openalex.org/W2120070286","https://openalex.org/W2132716318","https://openalex.org/W2140498074","https://openalex.org/W2145355816","https://openalex.org/W2156378819","https://openalex.org/W2160466713","https://openalex.org/W2163205418","https://openalex.org/W2163691729","https://openalex.org/W2164292937","https://openalex.org/W2165136032","https://openalex.org/W2167156722","https://openalex.org/W2175803345","https://openalex.org/W2211523930","https://openalex.org/W2401973235","https://openalex.org/W2427721238","https://openalex.org/W4230705710"],"related_works":["https://openalex.org/W2127930765","https://openalex.org/W2145033876","https://openalex.org/W2061951020","https://openalex.org/W2118809819","https://openalex.org/W1971293891","https://openalex.org/W2094503340","https://openalex.org/W2041808638","https://openalex.org/W3119105383","https://openalex.org/W2010399667","https://openalex.org/W2008806010"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-08-23T00:00:00"}