{"id":"https://openalex.org/W2497635207","doi":"https://doi.org/10.1039/c6ra15166c","title":"Development of an \u03b1-linolenic acid containing soft nanocarrier for oral delivery: in vitro and in vivo evaluation","display_name":"Development of an \u03b1-linolenic acid containing soft nanocarrier for oral delivery: in vitro and in vivo evaluation","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2497635207","doi":"https://doi.org/10.1039/c6ra15166c","mag":"2497635207"},"language":"en","primary_location":{"id":"doi:10.1039/c6ra15166c","doi":"https://doi.org/10.1039/c6ra15166c","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c6ra15166c","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007793706","display_name":"Mahendra Vikram Singh","orcid":"https://orcid.org/0000-0002-3807-6815","observed_orcids":["https://orcid.org/0000-0002-3807-6815"]},"institutions":[{"id":"https://openalex.org/I143247161","display_name":"Babasaheb Bhimrao Ambedkar University","ror":"https://ror.org/04x7ccp17","country_code":"IN","type":"education","lineage":["https://openalex.org/I143247161"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mahendra Singh","raw_affiliation_strings":["Babasaheb Bhimrao Ambedkar University (A Central University)","Department of Pharmaceutical Sciences","India","Lucknow-226025","Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Babasaheb Bhimrao Ambedkar University (A Central University)","institution_ids":["https://openalex.org/I143247161"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Lucknow-226025","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India","institution_ids":["https://openalex.org/I143247161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068625778","display_name":"Jovita Kanoujia","orcid":"https://orcid.org/0000-0002-4766-9890","observed_orcids":["https://orcid.org/0000-0002-4766-9890"]},"institutions":[{"id":"https://openalex.org/I143247161","display_name":"Babasaheb Bhimrao Ambedkar University","ror":"https://ror.org/04x7ccp17","country_code":"IN","type":"education","lineage":["https://openalex.org/I143247161"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jovita Kanoujia","raw_affiliation_strings":["Babasaheb Bhimrao Ambedkar University (A Central University)","Department of Pharmaceutical Sciences","India","Lucknow-226025","Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Babasaheb Bhimrao Ambedkar University (A Central University)","institution_ids":["https://openalex.org/I143247161"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Lucknow-226025","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India","institution_ids":["https://openalex.org/I143247161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033556364","display_name":"Pooja Singh","orcid":"https://orcid.org/0000-0003-4956-8644","observed_orcids":["https://orcid.org/0000-0003-4956-8644"]},"institutions":[{"id":"https://openalex.org/I143247161","display_name":"Babasaheb Bhimrao Ambedkar University","ror":"https://ror.org/04x7ccp17","country_code":"IN","type":"education","lineage":["https://openalex.org/I143247161"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pooja Singh","raw_affiliation_strings":["Babasaheb Bhimrao Ambedkar University (A Central University)","Department of Pharmaceutical Sciences","India","Lucknow-226025","Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Babasaheb Bhimrao Ambedkar University (A Central University)","institution_ids":["https://openalex.org/I143247161"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Lucknow-226025","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India","institution_ids":["https://openalex.org/I143247161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102758885","display_name":"Chandra Bhushan Tripathi","orcid":"https://orcid.org/0000-0003-1092-0620","observed_orcids":["https://orcid.org/0000-0003-1092-0620"]},"institutions":[{"id":"https://openalex.org/I143247161","display_name":"Babasaheb Bhimrao Ambedkar University","ror":"https://ror.org/04x7ccp17","country_code":"IN","type":"education","lineage":["https://openalex.org/I143247161"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Chandra B. Tripathi","raw_affiliation_strings":["Babasaheb Bhimrao Ambedkar University (A Central University)","Department of Pharmaceutical Sciences","India","Lucknow-226025","Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Babasaheb Bhimrao Ambedkar University (A Central University)","institution_ids":["https://openalex.org/I143247161"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Lucknow-226025","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India","institution_ids":["https://openalex.org/I143247161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034673964","display_name":"Malti Arya","orcid":"https://orcid.org/0000-0002-6082-1586","observed_orcids":["https://orcid.org/0000-0002-6082-1586"]},"institutions":[{"id":"https://openalex.org/I143247161","display_name":"Babasaheb Bhimrao Ambedkar University","ror":"https://ror.org/04x7ccp17","country_code":"IN","type":"education","lineage":["https://openalex.org/I143247161"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Malti Arya","raw_affiliation_strings":["Babasaheb Bhimrao Ambedkar University (A Central University)","Department of Pharmaceutical Sciences","India","Lucknow-226025","Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Babasaheb Bhimrao Ambedkar University (A Central University)","institution_ids":["https://openalex.org/I143247161"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Lucknow-226025","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India","institution_ids":["https://openalex.org/I143247161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006540540","display_name":"Poonam Parashar","orcid":"https://orcid.org/0000-0003-0286-8615","observed_orcids":["https://orcid.org/0000-0003-0286-8615"]},"institutions":[{"id":"https://openalex.org/I143247161","display_name":"Babasaheb Bhimrao Ambedkar University","ror":"https://ror.org/04x7ccp17","country_code":"IN","type":"education","lineage":["https://openalex.org/I143247161"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Poonam Parashar","raw_affiliation_strings":["Babasaheb Bhimrao Ambedkar University (A Central University)","Department of Pharmaceutical Sciences","India","Lucknow-226025","Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Babasaheb Bhimrao Ambedkar University (A Central University)","institution_ids":["https://openalex.org/I143247161"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Lucknow-226025","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India","institution_ids":["https://openalex.org/I143247161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008948224","display_name":"Vivek Ranjan Sinha","orcid":"https://orcid.org/0000-0002-2578-7722","observed_orcids":["https://orcid.org/0000-0002-2578-7722"]},"institutions":[{"id":"https://openalex.org/I51452335","display_name":"Panjab University","ror":"https://ror.org/04p2sbk06","country_code":"IN","type":"education","lineage":["https://openalex.org/I51452335"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vivek R. Sinha","raw_affiliation_strings":["Chandigarh-160014 (UT)","India","Panjab University","University Institute of Pharmaceutical Sciences","University Institute of Pharmaceutical Sciences, Panjab University, Sector-14, Chandigarh-160014 (UT), India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chandigarh-160014 (UT)","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Panjab University","institution_ids":["https://openalex.org/I51452335"]},{"raw_affiliation_string":"University Institute of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"University Institute of Pharmaceutical Sciences, Panjab University, Sector-14, Chandigarh-160014 (UT), India","institution_ids":["https://openalex.org/I51452335"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012146396","display_name":"Shubhini Awasthi Saraf","orcid":"https://orcid.org/0000-0002-4180-0931","observed_orcids":["https://orcid.org/0000-0002-4180-0931","https://orcid.org/0000-0002-8384-9370"]},"institutions":[{"id":"https://openalex.org/I143247161","display_name":"Babasaheb Bhimrao Ambedkar University","ror":"https://ror.org/04x7ccp17","country_code":"IN","type":"education","lineage":["https://openalex.org/I143247161"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Shubhini A. Saraf","raw_affiliation_strings":["Babasaheb Bhimrao Ambedkar University (A Central University)","Department of Pharmaceutical Sciences","India","Lucknow-226025","Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Babasaheb Bhimrao Ambedkar University (A Central University)","institution_ids":["https://openalex.org/I143247161"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences","institution_ids":[]},{"raw_affiliation_string":"India","institution_ids":[]},{"raw_affiliation_string":"Lucknow-226025","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya Vihar, Raebareli Road, Lucknow-226025, U.P., India","institution_ids":["https://openalex.org/I143247161"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012146396"],"corresponding_institution_ids":["https://openalex.org/I143247161"],"apc_list":{"value":850,"currency":"GBP","value_usd":1042},"apc_paid":null,"fwci":1.5633,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.75881057,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"6","issue":"81","first_page":"77590","last_page":"77602"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.6395999789237976,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.6395999789237976,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.14329999685287476,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10411","display_name":"Proteins in Food Systems","score":0.0835999995470047,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-linolenic-acid","display_name":"alpha-linolenic acid","score":0.9900000095367432},{"id":"https://openalex.org/keywords/oral-drug-delivery","display_name":"oral drug delivery","score":0.9449999928474426},{"id":"https://openalex.org/keywords/microemulsions","display_name":"microemulsions","score":0.9340000152587891},{"id":"https://openalex.org/keywords/simvastatin","display_name":"simvastatin","score":0.8999999761581421},{"id":"https://openalex.org/keywords/lipid-lowering","display_name":"lipid lowering","score":0.8550000190734863},{"id":"https://openalex.org/keywords/synergistic-effect","display_name":"synergistic effect","score":0.7279999852180481},{"id":"https://openalex.org/keywords/in-vitro-testing","display_name":"in vitro evaluation","score":0.6150000095367432},{"id":"https://openalex.org/keywords/in-vivo-evaluation","display_name":"in vivo evaluation","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C18150654","wikidata":"https://www.wikidata.org/wiki/Q17153796","display_name":"Nanocarriers","level":3,"score":0.8918026685714722},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7367972731590271},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.6590692400932312},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6466948986053467},{"id":"https://openalex.org/C2776176469","wikidata":"https://www.wikidata.org/wiki/Q418650","display_name":"Linolenic acid","level":4,"score":0.5553697347640991},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3828147053718567},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.32346630096435547},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.2500768303871155},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.2015996277332306},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15150713920593262},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.14057159423828125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13578572869300842},{"id":"https://openalex.org/C2780809830","wikidata":"https://www.wikidata.org/wiki/Q407426","display_name":"Linoleic acid","level":3,"score":0.07993057370185852},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.06703397631645203}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/c6ra15166c","doi":"https://doi.org/10.1039/c6ra15166c","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c6ra15166c","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320336163","display_name":"Institute of Psychology, Chinese Academy of Sciences","ror":"https://ror.org/03j7v5j15"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W69779666","https://openalex.org/W119853313","https://openalex.org/W1898641180","https://openalex.org/W1933509585","https://openalex.org/W1964043344","https://openalex.org/W1970703917","https://openalex.org/W1971199964","https://openalex.org/W1974647064","https://openalex.org/W1976874152","https://openalex.org/W1980889824","https://openalex.org/W1982040758","https://openalex.org/W1984540184","https://openalex.org/W1989426152","https://openalex.org/W1991916654","https://openalex.org/W2013740041","https://openalex.org/W2025931589","https://openalex.org/W2028531434","https://openalex.org/W2036193039","https://openalex.org/W2038338711","https://openalex.org/W2045151148","https://openalex.org/W2048166842","https://openalex.org/W2052763331","https://openalex.org/W2055585063","https://openalex.org/W2055602961","https://openalex.org/W2060880839","https://openalex.org/W2064910281","https://openalex.org/W2068977057","https://openalex.org/W2077668582","https://openalex.org/W2086354039","https://openalex.org/W2101171473","https://openalex.org/W2115897413","https://openalex.org/W2132010550","https://openalex.org/W2157353725","https://openalex.org/W2171497934","https://openalex.org/W4211174792","https://openalex.org/W4240053266","https://openalex.org/W4253445304"],"related_works":["https://openalex.org/W2530824765","https://openalex.org/W2093928566","https://openalex.org/W6987889899","https://openalex.org/W2349858388","https://openalex.org/W2769848125","https://openalex.org/W2735903466","https://openalex.org/W3115017336","https://openalex.org/W2790319943","https://openalex.org/W2073983855","https://openalex.org/W4302009929"],"abstract_inverted_index":{"Use":[0],"of":[1,14,18],"\u03b1-linolenic":[2],"acid":[3],"as":[4],"an":[5],"oil":[6,15],"phase":[7],"for":[8],"microemulsion":[9],"preparation":[10],"with":[11,23],"synergistic":[12],"effect":[13],"in":[16,21],"lowering":[17],"lipid":[19],"levels":[20],"combination":[22],"simvastatin.":[24]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-08-23T00:00:00"}