{"id":"https://openalex.org/W2496569809","doi":"https://doi.org/10.1016/b978-0-12-381422-7.10016-1","title":"Hematopoietic Stem Cell Properties, Markers, and Therapeutics","display_name":"Hematopoietic Stem Cell Properties, Markers, and Therapeutics","publication_year":2010,"publication_date":"2010-12-14","ids":{"openalex":"https://openalex.org/W2496569809","doi":"https://doi.org/10.1016/b978-0-12-381422-7.10016-1","mag":"2496569809"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-381422-7.10016-1","doi":"https://doi.org/10.1016/b978-0-12-381422-7.10016-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-381422-7.10016-1","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Principles of Regenerative Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2588337149","display_name":"Principles of Regenerative Medicine"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021612565","display_name":"Kuan\u2010Yin Lin","orcid":"https://orcid.org/0000-0001-6877-5345","observed_orcids":["https://orcid.org/0000-0001-6877-5345"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kuanyin K. Lin","raw_affiliation_strings":["Center for Cell and Gene Therapy, Stem Cell and Regenerative Medicine Center,Department of Pathology and Immunology, Baylor College of Medicine, Houston,TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Cell and Gene Therapy, Stem Cell and Regenerative Medicine Center,Department of Pathology and Immunology, Baylor College of Medicine, Houston,TX, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066248565","display_name":"Grant Anthony Challen","orcid":"https://orcid.org/0000-0003-4669-8814","observed_orcids":["https://orcid.org/0000-0003-4669-8814"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Grant A. Challen","raw_affiliation_strings":["Center for Cell and Gene Therapy, Stem Cell and Regenerative Medicine Center,Department of Pathology and Immunology, Baylor College of Medicine, Houston,TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Cell and Gene Therapy, Stem Cell and Regenerative Medicine Center,Department of Pathology and Immunology, Baylor College of Medicine, Houston,TX, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074463940","display_name":"Margaret A. Goodell","orcid":"https://orcid.org/0000-0003-1111-2932","observed_orcids":["https://orcid.org/0000-0003-1111-2932"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret A. Goodell","raw_affiliation_strings":["Center for Cell and Gene Therapy, Stem Cell and Regenerative Medicine Center,Department of Pathology and Immunology, Baylor College of Medicine, Houston,TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Cell and Gene Therapy, Stem Cell and Regenerative Medicine Center,Department of Pathology and Immunology, Baylor College of Medicine, Houston,TX, USA","institution_ids":["https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I181547552"],"apc_list":null,"apc_paid":null,"fwci":1.6197,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.87051143,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"273","last_page":"284"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12919","display_name":"Blood disorders and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hematopoietic-stem-cells","display_name":"hematopoietic stem cells","score":1.0},{"id":"https://openalex.org/keywords/hematopoiesis","display_name":"hematopoiesis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/self-renewal","display_name":"self-renewal","score":0.8709999918937683},{"id":"https://openalex.org/keywords/bone-marrow-microenvironment","display_name":"bone marrow microenvironment","score":0.7540000081062317},{"id":"https://openalex.org/keywords/n-cadherin","display_name":"N-cadherin","score":0.7639999985694885},{"id":"https://openalex.org/keywords/notch1","display_name":"Notch1","score":0.9940000176429749},{"id":"https://openalex.org/keywords/tie2","display_name":"Tie2","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cxcr4","display_name":"CXCR4","score":0.890999972820282},{"id":"https://openalex.org/keywords/long-term-hscs","display_name":"long-term HSCs","score":0.6769999861717224},{"id":"https://openalex.org/keywords/hematopoietic-progenitor-cells","display_name":"hematopoietic progenitor cells","score":0.7889999747276306}],"concepts":[{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.7445611357688904},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.7030360102653503},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.6898510456085205},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6325861215591431},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5974714159965515},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.5812687277793884},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.5354601740837097},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4967411160469055},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.45497772097587585},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.42777228355407715},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.32827746868133545},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.19808083772659302},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0664655864238739},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-12-381422-7.10016-1","doi":"https://doi.org/10.1016/b978-0-12-381422-7.10016-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-381422-7.10016-1","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Principles of Regenerative Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/16","score":0.6499999761581421,"display_name":"Peace, justice, and strong institutions"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":129,"referenced_works":["https://openalex.org/W108816917","https://openalex.org/W1556673058","https://openalex.org/W1562891803","https://openalex.org/W1569324890","https://openalex.org/W1575638464","https://openalex.org/W1584828020","https://openalex.org/W1606850112","https://openalex.org/W1607807757","https://openalex.org/W1816761971","https://openalex.org/W1932232911","https://openalex.org/W1970634781","https://openalex.org/W1970895440","https://openalex.org/W1972764534","https://openalex.org/W1973035870","https://openalex.org/W1973879435","https://openalex.org/W1975025595","https://openalex.org/W1975268103","https://openalex.org/W1977297606","https://openalex.org/W1977764876","https://openalex.org/W1979798449","https://openalex.org/W1980867815","https://openalex.org/W1982130774","https://openalex.org/W1984621921","https://openalex.org/W1984850507","https://openalex.org/W1985801522","https://openalex.org/W1989041292","https://openalex.org/W1989543257","https://openalex.org/W1991248271","https://openalex.org/W1991374176","https://openalex.org/W1995286997","https://openalex.org/W1999047431","https://openalex.org/W2000108021","https://openalex.org/W2000355031","https://openalex.org/W2000503805","https://openalex.org/W2001627351","https://openalex.org/W2001823825","https://openalex.org/W2005553463","https://openalex.org/W2005994924","https://openalex.org/W2010348699","https://openalex.org/W2011059916","https://openalex.org/W2011712807","https://openalex.org/W2016536941","https://openalex.org/W2017625115","https://openalex.org/W2017907565","https://openalex.org/W2021050536","https://openalex.org/W2021550815","https://openalex.org/W2021553913","https://openalex.org/W2027255730","https://openalex.org/W2028196271","https://openalex.org/W2028256918","https://openalex.org/W2031316068","https://openalex.org/W2036055444","https://openalex.org/W2037262941","https://openalex.org/W2038198568","https://openalex.org/W2041359271","https://openalex.org/W2042982622","https://openalex.org/W2043163249","https://openalex.org/W2043872317","https://openalex.org/W2045000380","https://openalex.org/W2045907249","https://openalex.org/W2046305449","https://openalex.org/W2046516822","https://openalex.org/W2050314360","https://openalex.org/W2051446802","https://openalex.org/W2051740914","https://openalex.org/W2052904272","https://openalex.org/W2057847245","https://openalex.org/W2058205936","https://openalex.org/W2058501235","https://openalex.org/W2060610551","https://openalex.org/W2061656021","https://openalex.org/W2062133747","https://openalex.org/W2063486944","https://openalex.org/W2067190562","https://openalex.org/W2067946773","https://openalex.org/W2068499309","https://openalex.org/W2069209063","https://openalex.org/W2070793750","https://openalex.org/W2072411272","https://openalex.org/W2077330278","https://openalex.org/W2080961105","https://openalex.org/W2083632015","https://openalex.org/W2085033687","https://openalex.org/W2085868655","https://openalex.org/W2086668227","https://openalex.org/W2088430282","https://openalex.org/W2088438660","https://openalex.org/W2090786449","https://openalex.org/W2092084671","https://openalex.org/W2093681591","https://openalex.org/W2093958228","https://openalex.org/W2097925286","https://openalex.org/W2099889778","https://openalex.org/W2100378064","https://openalex.org/W2106715658","https://openalex.org/W2109794889","https://openalex.org/W2111759041","https://openalex.org/W2112528263","https://openalex.org/W2114982358","https://openalex.org/W2115226431","https://openalex.org/W2118453722","https://openalex.org/W2119739306","https://openalex.org/W2120123622","https://openalex.org/W2123938765","https://openalex.org/W2124268517","https://openalex.org/W2125418204","https://openalex.org/W2131263031","https://openalex.org/W2133137848","https://openalex.org/W2134924448","https://openalex.org/W2137440275","https://openalex.org/W2137956382","https://openalex.org/W2141796213","https://openalex.org/W2141837666","https://openalex.org/W2141874645","https://openalex.org/W2145185496","https://openalex.org/W2150071496","https://openalex.org/W2150409084","https://openalex.org/W2151955120","https://openalex.org/W2152414109","https://openalex.org/W2157187112","https://openalex.org/W2158337417","https://openalex.org/W2163065691","https://openalex.org/W2165521277","https://openalex.org/W2169846226","https://openalex.org/W2184156621","https://openalex.org/W2274884072","https://openalex.org/W2280816045","https://openalex.org/W2395880515","https://openalex.org/W2406608326"],"related_works":["https://openalex.org/W40848976","https://openalex.org/W2272937510","https://openalex.org/W2016818042","https://openalex.org/W601440694","https://openalex.org/W1492326354","https://openalex.org/W2068839441","https://openalex.org/W4200224750","https://openalex.org/W2281459924","https://openalex.org/W4249998473","https://openalex.org/W4401190694"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-08-23T00:00:00"}