{"id":"https://openalex.org/W2494767840","doi":null,"title":"How Molecular adjustment can minimize Nicotine's effects in human brain","display_name":"How Molecular adjustment can minimize Nicotine's effects in human brain","publication_year":2016,"publication_date":"2016-02-01","ids":{"openalex":"https://openalex.org/W2494767840","mag":"2494767840"},"language":"en","primary_location":{"id":"pmh:oai:ojs.research-advances.org:article/44","doi":null,"is_oa":true,"landing_page_url":"http://research-advances.org/index.php/IRAJAS/article/view/44","pdf_url":"http://research-advances.org/index.php/IRAJAS/article/view/44","source":{"id":"https://openalex.org/S4306400086","display_name":"Institute of Research Advances (Institute of Research Advances Press Of Institute Of Research Advances)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IRA-International Journal of Applied Sciences (ISSN 2455-4499); Vol 1, No 2 (2015): December","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://research-advances.org/index.php/IRAJAS/article/view/44","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051598046","display_name":"Anome Jose","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25112270","display_name":"Universidade Federal de Pernambuco","ror":"https://ror.org/047908t24","country_code":"BR","type":"education","lineage":["https://openalex.org/I25112270"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Anome Jose","raw_affiliation_strings":["Research Fellow, Universidade Federal de Pernambuco, Recife"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Fellow, Universidade Federal de Pernambuco, Recife","institution_ids":["https://openalex.org/I25112270"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051598046"],"corresponding_institution_ids":["https://openalex.org/I25112270"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"1","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.8939999938011169,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.8939999938011169,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.09560000151395798,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nicotine-dependence","display_name":"nicotine dependence","score":0.8600000143051147},{"id":"https://openalex.org/keywords/brain-lipids","display_name":"brain lipids","score":0.6899999976158142},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.4350000023841858},{"id":"https://openalex.org/keywords/smoking-cessation","display_name":"smoking cessation","score":0.9210000038146973}],"concepts":[{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.7072724103927612},{"id":"https://openalex.org/C28719098","wikidata":"https://www.wikidata.org/wiki/Q44946","display_name":"Point (geometry)","level":2,"score":0.4923199415206909},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3836372494697571},{"id":"https://openalex.org/C52119013","wikidata":"https://www.wikidata.org/wiki/Q50637","display_name":"Art history","level":1,"score":0.32098448276519775},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.3023802638053894},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.25410839915275574},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.08481118083000183},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ojs.research-advances.org:article/44","doi":null,"is_oa":true,"landing_page_url":"http://research-advances.org/index.php/IRAJAS/article/view/44","pdf_url":"http://research-advances.org/index.php/IRAJAS/article/view/44","source":{"id":"https://openalex.org/S4306400086","display_name":"Institute of Research Advances (Institute of Research Advances Press Of Institute Of Research Advances)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IRA-International Journal of Applied Sciences (ISSN 2455-4499); Vol 1, No 2 (2015): December","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2494767840","doi":null,"is_oa":true,"landing_page_url":"http://research-advances.org/index.php/IRAJAS/article/view/44/44","pdf_url":null,"source":{"id":"https://openalex.org/S4210202547","display_name":"IRA-International Journal of Applied Sciences","issn_l":"2455-4499","issn":["2455-4499"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"IRA-International Journal of Applied Sciences","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ojs.research-advances.org:article/44","doi":null,"is_oa":true,"landing_page_url":"http://research-advances.org/index.php/IRAJAS/article/view/44","pdf_url":"http://research-advances.org/index.php/IRAJAS/article/view/44","source":{"id":"https://openalex.org/S4306400086","display_name":"Institute of Research Advances (Institute of Research Advances Press Of Institute Of Research Advances)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IRA-International Journal of Applied Sciences (ISSN 2455-4499); Vol 1, No 2 (2015): December","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2494767840.pdf","grobid_xml":"https://content.openalex.org/works/W2494767840.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W1978348024","https://openalex.org/W1991315413","https://openalex.org/W2003432832","https://openalex.org/W2050671544","https://openalex.org/W2060285232","https://openalex.org/W2077301822","https://openalex.org/W2123035658","https://openalex.org/W2145107116","https://openalex.org/W2162253352"],"related_works":["https://openalex.org/W2791288749","https://openalex.org/W2339779978","https://openalex.org/W2955138165","https://openalex.org/W2006721393","https://openalex.org/W6903742926","https://openalex.org/W2995289366","https://openalex.org/W2324173313","https://openalex.org/W2085237323","https://openalex.org/W4406881471","https://openalex.org/W7097989558"],"abstract_inverted_index":{"Researchers":[0],"at":[1,132],"The":[2,32,134],"Scripps":[3],"Research":[4],"Institute":[5,128],"(TSRI)":[6],"have":[7],"found":[8],"that":[9,42],"a":[10,21,40,43,100],"lipid":[11,52],"(fat":[12],"atom)":[13],"in":[14,35,71,142],"mind":[15],"cells":[16],"might":[17],"go":[18],"about":[19],"as":[20],"\"change\"":[22],"to":[23,29,39,53,63,76],"increment":[24],"or":[25,48],"diminish":[26],"the":[27,95,105,118,126,139,143,147],"inspiration":[28],"expend":[30],"nicotine.":[31],"group's":[33],"discoveries":[34],"creature":[36],"models":[37],"point":[38,78],"way":[41],"medication":[44],"may":[45],"some":[46],"time":[47],"another":[49],"return":[50],"this":[51,77],"typical":[54],"levels,":[55],"maybe":[56],"making":[57],"it":[58],"less":[59],"demanding":[60],"for":[61,129,138],"smokers":[62],"stop.":[64],"\"We":[65],"knew":[66],"these":[67],"lipids":[68],"were":[69],"embroiled":[70],"nicotine":[72],"dependence,":[73],"however":[74],"up":[75],"controlling":[79],"their":[80],"union":[81],"was":[82,136],"not":[83],"pharmacologically":[84],"practical,\"":[85],"said":[86],"TSRI":[87,106],"Professor":[88,109],"Loren":[89],"(\"Larry\")":[90],"Parsons,":[91],"senior":[92],"creator":[93],"of":[94,108,117,120,146,150],"new":[96],"study,":[97],"which":[98],"included":[99],"nearby":[101],"joint":[102],"effort":[103],"with":[104],"labs":[107],"Marisa":[110],"Roberto":[111],"and":[112,123],"Benjamin":[113],"F.":[114],"Cravatt,":[115],"seat":[116],"Department":[119],"Chemical":[121,130],"Physiology":[122],"individual":[124],"from":[125],"Skaggs":[127],"Biology":[131],"TSRI.":[133],"study":[135],"distributed":[137],"current":[140],"week":[141],"diary":[144],"Proceedings":[145],"National":[148],"Academy":[149],"Sciences.":[151]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-08-23T00:00:00"}
