{"id":"https://openalex.org/W2494635045","doi":null,"title":"ANTICONVULSANT SCREENING OF THE METHANOLIC LEAF EXTRACT OF TAPINANTHUS DODONEIFOLIUS DC DANSER (LORANTHACEAE) IN PENTYLENETETRAZOLE INDUCED SEIZURE MODEL IN ALBINO RATS","display_name":"ANTICONVULSANT SCREENING OF THE METHANOLIC LEAF EXTRACT OF TAPINANTHUS DODONEIFOLIUS DC DANSER (LORANTHACEAE) IN PENTYLENETETRAZOLE INDUCED SEIZURE MODEL IN ALBINO RATS","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2494635045","mag":"2494635045"},"language":"en","primary_location":{"id":"mag:2494635045","doi":null,"is_oa":false,"landing_page_url":"http://www.ijpbs.net/cms/php/upload/4536_pdf.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764788474","display_name":"International Journal of Pharma and Bio Sciences","issn_l":"0975-6299","issn":["0975-6299"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322697007","host_organization_name":"Ubitech Solutions","host_organization_lineage":["https://openalex.org/P4322697007"],"host_organization_lineage_names":["Ubitech Solutions"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Pharma and Bio Sciences","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086002767","display_name":"Uthman Garba S","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Uthman Garba S","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014661213","display_name":"Nikilesh Samuel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Bika Samuel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5045158192","display_name":"Timothy Samuel Y","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timothy Samuel Y","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.428,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.62368058,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"6","issue":"3","first_page":"245","last_page":"250"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.7958999872207642,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.7958999872207642,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.1031000018119812,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13090","display_name":"Medicinal Plant Extracts Effects","score":0.07090000063180923,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anticonvulsant-activity","display_name":"anticonvulsant activity","score":0.9319999814033508},{"id":"https://openalex.org/keywords/pentylenetetrazole-induced-seizures","display_name":"pentylenetetrazole-induced seizures","score":0.9629999995231628},{"id":"https://openalex.org/keywords/clonic-convulsions","display_name":"clonic convulsions","score":0.8220000267028809},{"id":"https://openalex.org/keywords/methanolic-leaf-extract","display_name":"methanolic leaf extract","score":0.9160000085830688},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.7210000157356262},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.9330000281333923},{"id":"https://openalex.org/keywords/loranthaceae","display_name":"Loranthaceae","score":0.9269999861717224}],"concepts":[{"id":"https://openalex.org/C2777010014","wikidata":"https://www.wikidata.org/wiki/Q852376","display_name":"Convulsion","level":3,"score":0.9185096621513367},{"id":"https://openalex.org/C2779275196","wikidata":"https://www.wikidata.org/wiki/Q156691","display_name":"Loranthaceae","level":2,"score":0.7914787530899048},{"id":"https://openalex.org/C2775858608","wikidata":"https://www.wikidata.org/wiki/Q576618","display_name":"Anticonvulsant","level":3,"score":0.7497716546058655},{"id":"https://openalex.org/C2776175493","wikidata":"https://www.wikidata.org/wiki/Q210402","display_name":"Diazepam","level":2,"score":0.6812419295310974},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6130322813987732},{"id":"https://openalex.org/C2776148806","wikidata":"https://www.wikidata.org/wiki/Q912189","display_name":"Petroleum ether","level":3,"score":0.45240598917007446},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.43430453538894653},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.412916898727417},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.39497920870780945},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.3453320562839508},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3270137906074524},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2573498487472534},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.1857079565525055},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.069003164768219},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"mag:2494635045","doi":null,"is_oa":false,"landing_page_url":"http://www.ijpbs.net/cms/php/upload/4536_pdf.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764788474","display_name":"International Journal of Pharma and Bio Sciences","issn_l":"0975-6299","issn":["0975-6299"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322697007","host_organization_name":"Ubitech Solutions","host_organization_lineage":["https://openalex.org/P4322697007"],"host_organization_lineage_names":["Ubitech Solutions"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Pharma and Bio Sciences","raw_type":null},{"id":"mag:3147717294","doi":null,"is_oa":false,"landing_page_url":"http://www.ijpbs.net/cms/php/upload/4535_pdf.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1502482021","https://openalex.org/W1844949785","https://openalex.org/W1998192178","https://openalex.org/W2002956641","https://openalex.org/W2042464457","https://openalex.org/W2051682066","https://openalex.org/W2143268844","https://openalex.org/W2181352598"],"related_works":["https://openalex.org/W2263479930","https://openalex.org/W6977036920","https://openalex.org/W3043321485","https://openalex.org/W4399245142","https://openalex.org/W2372044899","https://openalex.org/W7150112926","https://openalex.org/W2189086268","https://openalex.org/W2523082275","https://openalex.org/W2057396639","https://openalex.org/W2187344743"],"abstract_inverted_index":{"Tapinanthus":[0,44,115,166],"dodoneifolius":[1,116,167],"DC":[2],"Danser":[3],"(Loranthaceae)":[4],"also":[5],"known":[6],"as":[7,112],"African":[8],"mistletoe":[9],"is":[10],"a":[11,70],"medicinal":[12],"plant":[13,50],"found":[14],"in":[15,57,104],"Nigeria":[16],"and":[17,65,79,109,118],"has":[18],"diverse":[19],"ethno-medical":[20],"uses":[21],"including":[22],"the":[23,35,39,49,90,124,137,152],"management":[24],"of":[25,29,38,43,48,89,126,136],"epilepsy.":[26],"The":[27,46,86,147,161],"aim":[28],"this":[30],"study":[31],"was":[32,74,93],"to":[33],"evaluate":[34],"anticonvulsant":[36,87,170],"activity":[37,88],"methanolic":[40],"leaf":[41],"extract":[42,91,138,148],"dodoneifolius.":[45],"leaves":[47],"were":[51,62],"collected":[52],"from":[53],"Azadirachta":[54],"indica":[55],"trees":[56],"Borno":[58],"state,":[59],"Nigeria.":[60],"They":[61],"air":[63],"dried,":[64],"then":[66,80],"size":[67],"reduced":[68],"into":[69],"coarse":[71],"powder":[72],"which":[73],"defatted":[75],"with":[76,107],"petroleum":[77],"ether":[78],"extracted":[81],"by":[82,95,102,130,157],"maceration":[83],"using":[84],"methanol.":[85],"obtained":[92,163],"investigated":[94],"studying":[96],"its":[97],"effect":[98],"on":[99],"seizures":[100],"induced":[101,129,144,159],"pentylenetetrazole":[103,131,143,158],"Wistar":[105],"rats":[106,153],"diazepam":[108],"sodium":[110],"valproate":[111],"standard":[113],"controls.":[114],"(125":[117],"250":[119],"mg/kg)":[120],"dose":[121,149],"dependently":[122,150],"delayed":[123],"onset":[125],"clonic":[127,145],"convulsion":[128],"(p<0.01).":[132],"However,":[133],"500":[134],"mg/kg":[135],"offered":[139],"100%":[140],"protection":[141],"against":[142,154],"convulsion.":[146,160],"protected":[151],"mortality":[155],"caused":[156],"data":[162],"suggest":[164],"that":[165],"possesses":[168],"significant":[169],"activity.":[171]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-08-23T00:00:00"}