{"id":"https://openalex.org/W2489948461","doi":"https://doi.org/10.1385/1-59259-424-7:87","title":"Gas Chromatography-Mass Spectrometric Analysis of Free 3-Chlorotyrosine, 3-Bromotyrosine, Ortho-Tyrosine, and 3-Nitrotyrosine in Biological Fluids","display_name":"Gas Chromatography-Mass Spectrometric Analysis of Free 3-Chlorotyrosine, 3-Bromotyrosine, Ortho-Tyrosine, and 3-Nitrotyrosine in Biological Fluids","publication_year":2003,"publication_date":"2003-11-14","ids":{"openalex":"https://openalex.org/W2489948461","doi":"https://doi.org/10.1385/1-59259-424-7:87","mag":"2489948461"},"language":"en","primary_location":{"id":"doi:10.1385/1-59259-424-7:87","doi":"https://doi.org/10.1385/1-59259-424-7:87","is_oa":false,"landing_page_url":"https://doi.org/10.1385/1-59259-424-7:87","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Biological Oxidative Stress","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W565146646","display_name":"Methods in Biological Oxidative Stress"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074798932","display_name":"Joseph P. Gaut","orcid":"https://orcid.org/0000-0002-9580-3951","observed_orcids":["https://orcid.org/0000-0002-9580-3951"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph P. Gaut","raw_affiliation_strings":["Department of Medicine, Washington University School of Medicine, St. Louis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Washington University School of Medicine, St. Louis","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027274726","display_name":"Jaeman Byun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaeman Byun","raw_affiliation_strings":["Department of Medicine, Washington University School of Medicine, St. Louis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Washington University School of Medicine, St. Louis","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035595391","display_name":"Jay W. Heinecke","orcid":"https://orcid.org/0000-0001-5246-0007","observed_orcids":["https://orcid.org/0000-0001-5246-0007"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jay W. Heinecke","raw_affiliation_strings":["Department of Medicine, Washington University School of Medicine, St. Louis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Washington University School of Medicine, St. Louis","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":0.4386,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.66926874,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"87","last_page":"92"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.5210000276565552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.21389999985694885,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.054499998688697815,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/3-chlorotyrosine","display_name":"3-chlorotyrosine","score":0.9580000042915344},{"id":"https://openalex.org/keywords/3-nitrotyrosine","display_name":"nitrotyrosine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tyrosine-derivatives","display_name":"tyrosine derivatives","score":0.6790000200271606},{"id":"https://openalex.org/keywords/reactive-oxidants","display_name":"reactive oxidants","score":0.828000009059906},{"id":"https://openalex.org/keywords/body-fluids","display_name":"biological fluids","score":0.722000002861023},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7099999785423279}],"concepts":[{"id":"https://openalex.org/C2779385521","wikidata":"https://www.wikidata.org/wiki/Q412383","display_name":"Nitrotyrosine","level":4,"score":0.6567689776420593},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.63177889585495},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.49330559372901917},{"id":"https://openalex.org/C192937433","wikidata":"https://www.wikidata.org/wiki/Q2134627","display_name":"Reactive intermediate","level":3,"score":0.4411540627479553},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4284891188144684},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27206650376319885},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.22249910235404968},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.16221576929092407},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1385/1-59259-424-7:87","doi":"https://doi.org/10.1385/1-59259-424-7:87","is_oa":false,"landing_page_url":"https://doi.org/10.1385/1-59259-424-7:87","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Biological Oxidative Stress","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.428600013256073,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/10","score":0.5899999737739563,"display_name":"Reduced inequalities"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1972824411","https://openalex.org/W2023518603","https://openalex.org/W2109571250","https://openalex.org/W4214589643"],"related_works":["https://openalex.org/W2008861924","https://openalex.org/W1979268626","https://openalex.org/W2998623378","https://openalex.org/W7005579303","https://openalex.org/W2074162548","https://openalex.org/W4388164531","https://openalex.org/W7097936892","https://openalex.org/W7011839223","https://openalex.org/W2330359903","https://openalex.org/W1992545031"],"abstract_inverted_index":{"Reactive":[0],"oxidants":[1,20],"are":[2],"thought":[3],"to":[4,15],"protect":[5],"the":[6,24],"host":[7,25],"by":[8],"destroying":[9],"invading":[10],"microbes":[11],"().":[12],"However,":[13],"owing":[14],"their":[16],"indiscriminate":[17],"nature,":[18],"reactive":[19],"might":[21],"also":[22],"damage":[23],"if":[26],"generated":[27],"inappropriately.":[28],"Indeed,":[29],"they":[30],"have":[31],"been":[32],"implicated":[33],"in":[34],"a":[35],"wide":[36],"array":[37],"of":[38],"pathologies":[39],"(,":[40],",":[41],").":[42]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-08-23T00:00:00"}