{"id":"https://openalex.org/W2486831947","doi":"https://doi.org/10.1016/b978-1-4832-8363-0.50296-2","title":"IMMUNOHISTOCHEMISTRY OF TYROSINE HYDROXYLASE (TH) IN HUMAN AND SIMIAN NERVOUS SYSTEMS: ALTERATIONS IN FAMILIAL DYSAUTONOMIA","display_name":"IMMUNOHISTOCHEMISTRY OF TYROSINE HYDROXYLASE (TH) IN HUMAN AND SIMIAN NERVOUS SYSTEMS: ALTERATIONS IN FAMILIAL DYSAUTONOMIA","publication_year":1979,"publication_date":"1979-01-01","ids":{"openalex":"https://openalex.org/W2486831947","doi":"https://doi.org/10.1016/b978-1-4832-8363-0.50296-2","mag":"2486831947"},"language":"en","primary_location":{"id":"doi:10.1016/b978-1-4832-8363-0.50296-2","doi":"https://doi.org/10.1016/b978-1-4832-8363-0.50296-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-1-4832-8363-0.50296-2","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Catecholamines: Basic and Clinical Frontiers","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4253763218","display_name":"Catecholamines: Basic and Clinical Frontiers"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"John Pearson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Pearson","raw_affiliation_strings":["New York University Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Medical Center, New York, NY","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066035925","display_name":"Leslie Brandeis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leslie Brandeis","raw_affiliation_strings":["New York University Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Medical Center, New York, NY","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066581474","display_name":"Menek Goldstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Menek Goldstein","raw_affiliation_strings":["New York University Medical Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Medical Center, New York, NY","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3306,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.53789004,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"966","last_page":"968"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12331","display_name":"Hereditary Neurological Disorders","score":0.7178000211715698,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12331","display_name":"Hereditary Neurological Disorders","score":0.7178000211715698,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.13449999690055847,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12237","display_name":"Congenital gastrointestinal and neural anomalies","score":0.031599998474121094,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tyrosine-hydroxylase","display_name":"tyrosine hydroxylase","score":1.0},{"id":"https://openalex.org/keywords/familial-dysautonomia","display_name":"familial dysautonomia","score":0.9900000095367432},{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"autonomic nervous system","score":0.6449999809265137},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.6060000061988831},{"id":"https://openalex.org/keywords/neurochemical-changes","display_name":"neurochemical changes","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C159167319","wikidata":"https://www.wikidata.org/wiki/Q420766","display_name":"Tyrosine hydroxylase","level":3,"score":0.8558480739593506},{"id":"https://openalex.org/C2779696190","wikidata":"https://www.wikidata.org/wiki/Q2325854","display_name":"Familial dysautonomia","level":2,"score":0.7601568698883057},{"id":"https://openalex.org/C2779543035","wikidata":"https://www.wikidata.org/wiki/Q620639","display_name":"Dysautonomia","level":3,"score":0.6964154243469238},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.6391482949256897},{"id":"https://openalex.org/C2776488936","wikidata":"https://www.wikidata.org/wiki/Q5452918","display_name":"Simian","level":3,"score":0.5023455619812012},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.45609816908836365},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4305419921875},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35580769181251526},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3275735378265381},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28478050231933594},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.22622990608215332},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.1443556845188141},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11189576983451843},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.04241359233856201},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-1-4832-8363-0.50296-2","doi":"https://doi.org/10.1016/b978-1-4832-8363-0.50296-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-1-4832-8363-0.50296-2","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Catecholamines: Basic and Clinical Frontiers","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1238819995","https://openalex.org/W1984770777","https://openalex.org/W2037411657","https://openalex.org/W2048062405"],"related_works":["https://openalex.org/W2495552073","https://openalex.org/W2498130678","https://openalex.org/W2078092944","https://openalex.org/W2083462523","https://openalex.org/W2477050774","https://openalex.org/W1529499037","https://openalex.org/W6926335318","https://openalex.org/W7073782343","https://openalex.org/W372795344","https://openalex.org/W2341520552"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-08-23T00:00:00"}