{"id":"https://openalex.org/W2485667397","doi":"https://doi.org/10.1016/j.ajpath.2016.05.020","title":"Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit","display_name":"Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit","publication_year":2016,"publication_date":"2016-07-26","ids":{"openalex":"https://openalex.org/W2485667397","doi":"https://doi.org/10.1016/j.ajpath.2016.05.020","mag":"2485667397","pmid":"https://pubmed.ncbi.nlm.nih.gov/27470713","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5012509"},"language":"en","primary_location":{"id":"doi:10.1016/j.ajpath.2016.05.020","doi":"https://doi.org/10.1016/j.ajpath.2016.05.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2016.05.020","pdf_url":"http://ajp.amjpathol.org/article/S0002944016302176/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://ajp.amjpathol.org/article/S0002944016302176/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104274844","display_name":"Patricia Rosa De Araujo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia Rosa de Araujo","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059087647","display_name":"Aparna Gorthi","orcid":"https://orcid.org/0000-0001-5935-4098","observed_orcids":["https://orcid.org/0000-0001-5935-4098"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aparna Gorthi","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053524086","display_name":"Acarizia E. da Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Acarizia E. da Silva","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065018435","display_name":"Sonal S. Tonapi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sonal S. Tonapi","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028267584","display_name":"Dat T. Vo","orcid":"https://orcid.org/0000-0001-9088-7132","observed_orcids":["https://orcid.org/0000-0001-9088-7132"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dat T. Vo","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Suzanne C. Burns","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne C. Burns","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mei Qiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mei Qiao","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045629825","display_name":"Philip J. Uren","orcid":"https://orcid.org/0000-0001-8092-4702","observed_orcids":["https://orcid.org/0000-0001-8092-4702"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip J. Uren","raw_affiliation_strings":["Molecular and Computational Biology Section, Division of Biological Sciences, University of Southern California, Los Angeles, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Computational Biology Section, Division of Biological Sciences, University of Southern California, Los Angeles, California","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111589344","display_name":"Zhi-Min Yuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhi-Min Yuan","raw_affiliation_strings":["Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021881572","display_name":"Alexander J.R. Bishop","orcid":"https://orcid.org/0000-0002-5742-4387","observed_orcids":["https://orcid.org/0000-0002-5742-4387"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alexander J.R. Bishop","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas. Electronic address: bishopa@uthscsa.edu","Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas. Electronic address: bishopa@uthscsa.edu","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042340056","display_name":"Luiz O. F. Penalva","orcid":"https://orcid.org/0000-0003-4491-6769","observed_orcids":["https://orcid.org/0000-0003-4491-6769"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Luiz O.F. Penalva","raw_affiliation_strings":["Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas. Electronic address: penalva@uthscsa.edu","Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas; Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas. Electronic address: penalva@uthscsa.edu","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas","institution_ids":["https://openalex.org/I165951966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5021881572","https://openalex.org/A5042340056"],"corresponding_institution_ids":["https://openalex.org/I165951966"],"apc_list":{"value":2800,"currency":"USD","value_usd":2800},"apc_paid":null,"fwci":3.8712,"has_fulltext":true,"cited_by_count":47,"citation_normalized_percentile":{"value":0.93276371,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"186","issue":"9","first_page":"2271","last_page":"2278"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.5952000021934509,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.5952000021934509,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.3352000117301941,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.025200000032782555,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/musashi-1","display_name":"Musashi-1","score":0.996999979019165},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.9139999747276306},{"id":"https://openalex.org/keywords/radioresistance-biology","display_name":"radioresistance (biology)","score":0.9190000295639038},{"id":"https://openalex.org/keywords/ionizing-radiation","display_name":"ionizing radiation","score":0.7870000004768372},{"id":"https://openalex.org/keywords/double-strand-break-repair","display_name":"DNA double-strand break repair","score":0.8980000019073486},{"id":"https://openalex.org/keywords/non-homologous-end-joining","display_name":"non-homologous end joining","score":0.9860000014305115},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.6299999952316284},{"id":"https://openalex.org/keywords/rna-binding-proteins","display_name":"RNA-binding proteins","score":0.796999990940094},{"id":"https://openalex.org/keywords/radiosensitization","display_name":"radiosensitization","score":0.6389999985694885}],"concepts":[{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.6950355172157288},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.6030299663543701},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6011923551559448},{"id":"https://openalex.org/C26114605","wikidata":"https://www.wikidata.org/wiki/Q7280368","display_name":"Radiation sensitivity","level":3,"score":0.5171744227409363},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.510445237159729},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46923476457595825},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.46056753396987915},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4418397545814514},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4276266396045685},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3772892653942108},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22943705320358276},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.13969340920448303},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10270494222640991},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011116","descriptor_name":"Polynucleotide 5'-Hydroxyl-Kinase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011836","descriptor_name":"Radiation Tolerance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020134","descriptor_name":"Catalytic Domain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D020552","descriptor_name":"Comet Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021881","descriptor_name":"DNA, Catalytic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053903","descriptor_name":"DNA Breaks, Double-Stranded","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.ajpath.2016.05.020","doi":"https://doi.org/10.1016/j.ajpath.2016.05.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2016.05.020","pdf_url":"http://ajp.amjpathol.org/article/S0002944016302176/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4473541","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5012509","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5012509","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5012509","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Pathol","raw_type":"Text"},{"id":"pmid:27470713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27470713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of pathology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.ajpath.2016.05.020","doi":"https://doi.org/10.1016/j.ajpath.2016.05.020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ajpath.2016.05.020","pdf_url":"http://ajp.amjpathol.org/article/S0002944016302176/pdf","source":{"id":"https://openalex.org/S145577119","display_name":"American Journal Of Pathology","issn_l":"0002-9440","issn":["0002-9440","1525-2191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Pathology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1107263452","display_name":"A screen for damage response genes using recombination","funder_award_id":"K22ES012264","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G2125549236","display_name":"A computational framework for global analysis of translation regulation","funder_award_id":"R01HG006015","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G2363395007","display_name":"Research Training Award","funder_award_id":"RP101491","funder_id":"https://openalex.org/F4320308129","funder_display_name":"Cancer Prevention and Research Institute of Texas"},{"id":"https://openalex.org/G3046138074","display_name":"Determination of Musashi1/CD44v6 signaling in mesenchymal glioma stem cells","funder_award_id":"7r21ca175875-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3077417178","display_name":"Comparing and contrasting the biology of damage survival at a genomic level","funder_award_id":"R15ES019128","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G4416676450","display_name":"Cancer Research Training Grant","funder_award_id":"RP140105","funder_id":"https://openalex.org/F4320308129","funder_display_name":"Cancer Prevention and Research Institute of Texas"},{"id":"https://openalex.org/G5114808721","display_name":null,"funder_award_id":"1R01HG006015-01A","funder_id":"https://openalex.org/F4320309319","funder_display_name":"Max and Minnie Tomerlin Voelcker Fund"},{"id":"https://openalex.org/G5837657685","display_name":"Improving etoposide treatment of Ewing's sarcoma","funder_award_id":"R01CA152063","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7206857136","display_name":null,"funder_award_id":"1R21CA175875-01A1","funder_id":"https://openalex.org/F4320309319","funder_display_name":"Max and Minnie Tomerlin Voelcker Fund"},{"id":"https://openalex.org/G82785621","display_name":null,"funder_award_id":"R21-CA175875","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000880981","display_name":"Cancer Biology Training Program","funder_award_id":"T32CA148724","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320307737","display_name":"Voices Against Brain Cancer","ror":"https://ror.org/017aszj34"},{"id":"https://openalex.org/F4320308129","display_name":"Cancer Prevention and Research Institute of Texas","ror":"https://ror.org/0003xa228"},{"id":"https://openalex.org/F4320309319","display_name":"Max and Minnie Tomerlin Voelcker Fund","ror":"https://ror.org/00951b249"},{"id":"https://openalex.org/F4320309536","display_name":"University of Texas System","ror":"https://ror.org/01gek1696"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2485667397.pdf","grobid_xml":"https://content.openalex.org/works/W2485667397.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1682971727","https://openalex.org/W1926743275","https://openalex.org/W1965439396","https://openalex.org/W1972550382","https://openalex.org/W1973397682","https://openalex.org/W1974082653","https://openalex.org/W1978124642","https://openalex.org/W1983479039","https://openalex.org/W2001513844","https://openalex.org/W2003581594","https://openalex.org/W2009606787","https://openalex.org/W2021429236","https://openalex.org/W2024101825","https://openalex.org/W2024221132","https://openalex.org/W2033056030","https://openalex.org/W2050480410","https://openalex.org/W2055624537","https://openalex.org/W2060469321","https://openalex.org/W2060551076","https://openalex.org/W2064502889","https://openalex.org/W2066074720","https://openalex.org/W2067517706","https://openalex.org/W2069584695","https://openalex.org/W2072454733","https://openalex.org/W2072806146","https://openalex.org/W2072858355","https://openalex.org/W2073679908","https://openalex.org/W2084316080","https://openalex.org/W2092629964","https://openalex.org/W2096287682","https://openalex.org/W2098016561","https://openalex.org/W2099776053","https://openalex.org/W2102627944","https://openalex.org/W2109102096","https://openalex.org/W2112535346","https://openalex.org/W2115862526","https://openalex.org/W2124255030","https://openalex.org/W2124482905","https://openalex.org/W2127361575","https://openalex.org/W2128016314","https://openalex.org/W2128793361","https://openalex.org/W2129785061","https://openalex.org/W2152569910","https://openalex.org/W2156063202","https://openalex.org/W2160532161","https://openalex.org/W2205491921","https://openalex.org/W2401658206"],"related_works":["https://openalex.org/W3173510580","https://openalex.org/W4387206766","https://openalex.org/W4409689691","https://openalex.org/W2108019002","https://openalex.org/W2317951626","https://openalex.org/W2897474496","https://openalex.org/W3148532480","https://openalex.org/W2008390728","https://openalex.org/W4382459533","https://openalex.org/W4403531636"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-08-23T00:00:00"}