{"id":"https://openalex.org/W2485632471","doi":null,"title":"Development of a new sensitive immunoradiometric assay for CA125: Mixed use of two monoclonal antibodies reactive with separate epitopes","display_name":"Development of a new sensitive immunoradiometric assay for CA125: Mixed use of two monoclonal antibodies reactive with separate epitopes","publication_year":1988,"publication_date":"1988-01-01","ids":{"openalex":"https://openalex.org/W2485632471","mag":"2485632471"},"language":"en","primary_location":{"id":"mag:2485632471","doi":null,"is_oa":false,"landing_page_url":"https://mdanderson.elsevierpure.com/en/publications/development-of-a-new-sensitive-immunoradiometric-assay-for-ca125-","pdf_url":null,"source":{"id":"https://openalex.org/S52144366","display_name":"Journal of tumor marker oncology","issn_l":"0886-3849","issn":["0886-3849"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of tumor marker oncology","raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109321454","display_name":"K Endo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K Endo","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047468226","display_name":"Yoichiro Matsuoka","orcid":"https://orcid.org/0000-0001-5864-7294","observed_orcids":["https://orcid.org/0000-0001-5864-7294"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Matsuoka","raw_affiliation_strings":["Kyoto University"],"raw_orcid":"https://orcid.org/0000-0002-6885-1982","affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Toshihiro Nakashima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshihiro Nakashima","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shin\u2010ichiro Fujii","orcid":"https://orcid.org/0000-0003-3586-3976","observed_orcids":["https://orcid.org/0000-0003-3586-3976"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shin\u2010ichiro Fujii","raw_affiliation_strings":["Kyoto University"],"raw_orcid":"https://orcid.org/0000-0003-3586-3976","affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111617018","display_name":"Mihoko Kunimatsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M. Kunimatsu","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062070934","display_name":"Tsuneo Saga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tsuneo Saga","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020520694","display_name":"YUKIHIKO WATANABE","orcid":"https://orcid.org/0000-0001-9435-8940","observed_orcids":["https://orcid.org/0000-0001-9435-8940"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Watanabe","raw_affiliation_strings":["Kyoto University"],"raw_orcid":"https://orcid.org/0000-0001-9435-8940","affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056752952","display_name":"Yasutaka Kawamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasutaka Kawamura","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111529407","display_name":"M Koizumi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M Koizumi","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J Konishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"J Konishi","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113599456","display_name":"Kanji Torizuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K Torizuka","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067595997","display_name":"Robert C. Bast","orcid":"https://orcid.org/0000-0003-4621-8462","observed_orcids":["https://orcid.org/0000-0003-4621-8462"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert C. Bast","raw_affiliation_strings":["Experimental Therapeutics"],"raw_orcid":"https://orcid.org/0000-0003-4621-8462","affiliations":[{"raw_affiliation_string":"Experimental Therapeutics","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7741,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.74378958,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"1","first_page":"65","last_page":"71"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.019700000062584877,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ca125","display_name":"CA125","score":0.9869999885559082},{"id":"https://openalex.org/keywords/immunoradiometric-assay","display_name":"immunoradiometric assay","score":0.9819999933242798},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.9549999833106995},{"id":"https://openalex.org/keywords/epitope-specific-antibodies","display_name":"epitope-specific antibodies","score":0.6589999794960022},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.671999990940094},{"id":"https://openalex.org/keywords/assay-sensitivity","display_name":"assay sensitivity","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C2778758028","wikidata":"https://www.wikidata.org/wiki/Q19597582","display_name":"Immunoradiometric assay","level":3,"score":0.8808781504631042},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.8387786149978638},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.7471393346786499},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4557866156101227},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.4280858337879181},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3839424252510071},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.37873348593711853},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3778683841228485},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3579978942871094},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34481245279312134},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10019803047180176}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2485632471","doi":null,"is_oa":false,"landing_page_url":"https://mdanderson.elsevierpure.com/en/publications/development-of-a-new-sensitive-immunoradiometric-assay-for-ca125-","pdf_url":null,"source":{"id":"https://openalex.org/S52144366","display_name":"Journal of tumor marker oncology","issn_l":"0886-3849","issn":["0886-3849"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of tumor marker oncology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2374351130","https://openalex.org/W2001174638","https://openalex.org/W2409130434","https://openalex.org/W1998018123","https://openalex.org/W2412275853","https://openalex.org/W1482943521","https://openalex.org/W2332308955","https://openalex.org/W2054590116","https://openalex.org/W4238646118","https://openalex.org/W932412875"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-08-23T00:00:00"}