{"id":"https://openalex.org/W2485437198","doi":"https://doi.org/10.1093/acprof:oso/9780199663927.003.0009","title":"Nutritional and Metabolic Adaptation","display_name":"Nutritional and Metabolic Adaptation","publication_year":2016,"publication_date":"2016-03-01","ids":{"openalex":"https://openalex.org/W2485437198","doi":"https://doi.org/10.1093/acprof:oso/9780199663927.003.0009","mag":"2485437198"},"language":"en","primary_location":{"id":"doi:10.1093/acprof:oso/9780199663927.003.0009","doi":"https://doi.org/10.1093/acprof:oso/9780199663927.003.0009","is_oa":false,"landing_page_url":"https://doi.org/10.1093/acprof:oso/9780199663927.003.0009","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Principles of Evolutionary Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W623481855","display_name":"Principles of Evolutionary Medicine"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058979039","display_name":"Peter David Gluckman","orcid":"https://orcid.org/0000-0002-5711-1655","observed_orcids":["https://orcid.org/0000-0002-5711-1655"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Gluckman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073261147","display_name":"Alan S. Beedle","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alan Beedle","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065836683","display_name":"Tatjana Buklija\u0161","orcid":"https://orcid.org/0000-0002-7170-5417","observed_orcids":["https://orcid.org/0000-0002-7170-5417"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tatjana Buklijas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050769090","display_name":"Felicia M. Low","orcid":"https://orcid.org/0000-0001-7136-9997","observed_orcids":["https://orcid.org/0000-0001-7136-9997"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Felicia Low","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100695706","display_name":"Mark A. Hanson","orcid":"https://orcid.org/0000-0002-6907-613X","observed_orcids":["https://orcid.org/0000-0002-6907-613X","https://orcid.org/0000-0002-0820-4521","https://orcid.org/0000-0002-7967-0730"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Hanson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7192,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.84439083,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"205","last_page":"236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.7294999957084656,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.7294999957084656,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.21289999783039093,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10010","display_name":"Obesity, Physical Activity, Diet","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nutritional-adaptation","display_name":"nutritional adaptation","score":0.7630000114440918},{"id":"https://openalex.org/keywords/human-evolution","display_name":"human evolution","score":0.8149999976158142},{"id":"https://openalex.org/keywords/evolutionary-mismatch","display_name":"evolutionary mismatch","score":0.8730000257492065},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.609000027179718},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.9399999976158142},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9900000095367432},{"id":"https://openalex.org/keywords/obesogenic-environment","display_name":"obesogenic environment","score":0.8209999799728394},{"id":"https://openalex.org/keywords/developmental-origins-of-health-and-disease","display_name":"developmental origins of health and disease","score":0.7879999876022339}],"concepts":[{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.6909705996513367},{"id":"https://openalex.org/C3018542373","wikidata":"https://www.wikidata.org/wiki/Q14901436","display_name":"Metabolic adaptation","level":3,"score":0.5772451758384705},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2770170569419861},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26549217104911804},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18165728449821472},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.11303973197937012},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.10848107933998108}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/acprof:oso/9780199663927.003.0009","doi":"https://doi.org/10.1093/acprof:oso/9780199663927.003.0009","is_oa":false,"landing_page_url":"https://doi.org/10.1093/acprof:oso/9780199663927.003.0009","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Principles of Evolutionary Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2802480559","https://openalex.org/W2284010517","https://openalex.org/W7028349899","https://openalex.org/W7221542491","https://openalex.org/W2890773880","https://openalex.org/W2225222866","https://openalex.org/W4403913688","https://openalex.org/W1547365532","https://openalex.org/W3173771212","https://openalex.org/W2499391949"],"abstract_inverted_index":{"The":[0],"bulk":[1],"of":[2,34,59,81,97,126],"human":[3,18],"evolution":[4],"occurred":[5],"in":[6,40,52,101,105,118,123],"a":[7,31,49,60,75],"nutritional":[8],"milieu":[9],"very":[10],"different":[11],"from":[12],"the":[13,17,57,79,85,94],"modern":[14],"one,":[15],"and":[16,36,43,54,128],"genotype":[19,61],"was":[20],"selected":[21],"to":[22,26,78,93,112],"be":[23],"well":[24],"adapted":[25],"that":[27,62],"milieu.":[28],"There":[29,46],"is":[30],"rising":[32,95],"incidence":[33,96],"obesity":[35,127],"its":[37],"associated":[38],"disorders":[39],"both":[41],"high-income":[42],"low/middle-income":[44],"countries.":[45],"has":[47],"been":[48],"rapid":[50],"change":[51,64],"diet":[53],"behavior":[55],"against":[56],"background":[58],"cannot":[63],"rapidly,":[65],"creating":[66],"an":[67,109,119],"evolutionary":[68],"mismatch.":[69,99],"Fixed":[70],"genetic":[71],"differences":[72],"make":[73],"only":[74],"small":[76],"contribution":[77],"prevalence":[80],"metabolic":[82,98,102,129],"disease":[83,130],"at":[84],"population":[86],"level.":[87],"Developmental":[88],"processes":[89],"may":[90],"also":[91],"contribute":[92],"Differences":[100],"phenotype":[103],"induced":[104],"development":[106],"can":[107],"alter":[108],"individual\u2019s":[110],"responses":[111],"later":[113],"challenges":[114],"such":[115,131],"as":[116,132],"living":[117],"\u201cobesogenic\u201d":[120],"environment,":[121],"resulting":[122],"greater":[124],"risk":[125],"type":[133],"2":[134],"diabetes.":[135]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-08-23T00:00:00"}