{"id":"https://openalex.org/W2484022162","doi":"https://doi.org/10.1007/978-1-349-04015-5_37","title":"Participation of endorphins in the regulation of pituitary function","display_name":"Participation of endorphins in the regulation of pituitary function","publication_year":1979,"publication_date":"1979-01-01","ids":{"openalex":"https://openalex.org/W2484022162","doi":"https://doi.org/10.1007/978-1-349-04015-5_37","mag":"2484022162"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-349-04015-5_37","doi":"https://doi.org/10.1007/978-1-349-04015-5_37","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-349-04015-5_37","pdf_url":null,"source":{"id":"https://openalex.org/S4306463716","display_name":"Palgrave Macmillan UK eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319703","host_organization_name":"Palgrave Macmillan","host_organization_lineage":["https://openalex.org/P4310319703","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Palgrave Macmillan","Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endorphins in Mental Health Research","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1580340214","display_name":"Endorphins in Mental Health Research"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048825104","display_name":"Alessandro Guidotti","orcid":"https://orcid.org/0000-0003-4480-0010","observed_orcids":["https://orcid.org/0000-0003-4480-0010"]},"institutions":[{"id":"https://openalex.org/I2802104953","display_name":"St. Elizabeths Hospital","ror":"https://ror.org/022w03s59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802104953","https://openalex.org/I4210099492"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Guidotti","raw_affiliation_strings":["Laboratory of Preclinical PharmacologyNational Institute of Mental Health, Saint Elizabeths Hospital, Washington, D.C, 20032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Preclinical PharmacologyNational Institute of Mental Health, Saint Elizabeths Hospital, Washington, D.C, 20032, USA","institution_ids":["https://openalex.org/I2802104953","https://openalex.org/I4210158500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066330973","display_name":"Lindsey Grandison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802104953","display_name":"St. Elizabeths Hospital","ror":"https://ror.org/022w03s59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802104953","https://openalex.org/I4210099492"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Grandison","raw_affiliation_strings":["Laboratory of Preclinical PharmacologyNational Institute of Mental Health, Saint Elizabeths Hospital, Washington, D.C, 20032, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Preclinical PharmacologyNational Institute of Mental Health, Saint Elizabeths Hospital, Washington, D.C, 20032, USA","institution_ids":["https://openalex.org/I2802104953","https://openalex.org/I4210158500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.339,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.89146165,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"416","last_page":"422"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endorphins","display_name":"endorphins","score":0.9900000095367432},{"id":"https://openalex.org/keywords/pituitary-function","display_name":"pituitary function","score":0.8339999914169312},{"id":"https://openalex.org/keywords/neuroendocrine-regulation","display_name":"neuroendocrine regulation","score":0.871999979019165},{"id":"https://openalex.org/keywords/opioid-peptides","display_name":"opioid peptides","score":0.7789999842643738},{"id":"https://openalex.org/keywords/acth-release","display_name":"ACTH release","score":0.6959999799728394},{"id":"https://openalex.org/keywords/growth-hormone","display_name":"growth hormone","score":0.7599999904632568},{"id":"https://openalex.org/keywords/prolactin","display_name":"prolactin","score":0.996999979019165},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.996999979019165},{"id":"https://openalex.org/keywords/morphine","display_name":"morphine","score":0.7960000038146973},{"id":"https://openalex.org/keywords/opioid-analgesics","display_name":"opioid analgesics","score":0.8659999966621399},{"id":"https://openalex.org/keywords/opioid-agonists","display_name":"opioid agonists","score":0.4819999933242798},{"id":"https://openalex.org/keywords/endogenous-opioids","display_name":"endogenous opioids","score":0.39800000190734863}],"concepts":[{"id":"https://openalex.org/C2778140631","wikidata":"https://www.wikidata.org/wiki/Q2026938","display_name":"Opiate","level":3,"score":0.72455894947052},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.6226789355278015},{"id":"https://openalex.org/C2778680817","wikidata":"https://www.wikidata.org/wiki/Q190528","display_name":"Endorphins","level":2,"score":0.5547246336936951},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.49479836225509644},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.44019615650177},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43715769052505493},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4313172698020935},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39073416590690613},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.28053784370422363},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.14541882276535034}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-349-04015-5_37","doi":"https://doi.org/10.1007/978-1-349-04015-5_37","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-349-04015-5_37","pdf_url":null,"source":{"id":"https://openalex.org/S4306463716","display_name":"Palgrave Macmillan UK eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319703","host_organization_name":"Palgrave Macmillan","host_organization_lineage":["https://openalex.org/P4310319703","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Palgrave Macmillan","Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endorphins in Mental Health Research","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W150676170","https://openalex.org/W1725391139","https://openalex.org/W1964614999","https://openalex.org/W1988626400","https://openalex.org/W1992916552","https://openalex.org/W2005530015","https://openalex.org/W2007488010","https://openalex.org/W2010051841","https://openalex.org/W2011668890","https://openalex.org/W2013019554","https://openalex.org/W2020195111","https://openalex.org/W2023858395","https://openalex.org/W2025414544","https://openalex.org/W2026154875","https://openalex.org/W2042908459","https://openalex.org/W2044872918","https://openalex.org/W2051612811","https://openalex.org/W2053243081","https://openalex.org/W2055753190","https://openalex.org/W2060658060","https://openalex.org/W2063769520","https://openalex.org/W2069420344","https://openalex.org/W2077017070","https://openalex.org/W2084970765","https://openalex.org/W2142662549","https://openalex.org/W2162264644","https://openalex.org/W2468886290"],"related_works":["https://openalex.org/W1972836142","https://openalex.org/W2077001323","https://openalex.org/W49232572","https://openalex.org/W54159658","https://openalex.org/W2134956158","https://openalex.org/W1541747833","https://openalex.org/W2411932825","https://openalex.org/W2416393240","https://openalex.org/W124604267","https://openalex.org/W2007488010"],"abstract_inverted_index":{"Long":[0],"before":[1],"the":[2,81,90,117,162,176,183,189],"discovery":[3],"of":[4,17,61,85,92,122,124,148,164],"endogenous":[5,86,154],"opiate":[6,20,87],"peptides,":[7],"pharmacologists":[8],"and":[9,22,36,53,56,67,83,103,116,173,182],"neuroendocrinologists":[10],"knew":[11],"that":[12,152],"there":[13],"were":[14,169],"several":[15,146],"points":[16],"interaction":[18],"between":[19],"drugs":[21],"endocrine":[23],"systems.":[24],"Narcotic":[25],"analgesics,":[26],"including":[27],"morphine,":[28],"are":[29,70],"known":[30],"to":[31],"alter":[32],"ACTH,":[33],"GH":[34],"(Gold":[35],"Ganong,":[37],"1967;":[38],"George,":[39],"1971),":[40],"prolactin":[41],"(PRL)":[42],"(Ojeda":[43],"et":[44,49,98,107,112,140],"al":[45,50,99,108,113,141],".":[46,51,100,109,114,133,137,142],"1974;":[47],"Martin":[48],"1975)":[52,115],"LH":[54],"(Barraclough":[55],"Sawyer,":[57],"1955)":[58],"release.":[59],"Loss":[60],"sexual":[62],"desire,":[63],"abnormal":[64],"menses,":[65],"infertility":[66],"spontaneous":[68],"abortion":[69],"frequently":[71],"observed":[72],"in":[73,89,161],"addicted":[74],"patients":[75],"(George,":[76],"1971;":[77],"Hollister,":[78],"1973).":[79],"Lately,":[80],"isolation":[82],"identification":[84],"peptides":[88,126,156],"brain":[91],"all":[93],"mammalian":[94],"species":[95],"studied":[96],"(Cox":[97],"1976;":[101,134],"Terenius":[102],"Wahlstr00F6m,":[104],"1975;":[105,110],"Hughes":[106],"Pasternak":[111],"synthesisof":[118],"an":[119],"impressive":[120],"series":[121],"derivatives":[123],"these":[125,153],"with":[127],"hormone":[128],"releasing":[129],"action":[130],"(Lien":[131],"etal":[132,136],"Shaar":[135],"1977;":[138],"Cusan":[139],"1977)":[143],"have":[144,158],"contributed":[145],"lines":[147],"indirect":[149],"evidence":[150],"suggesting":[151],"opiate-like":[155],"may":[157,185],"physiological":[159],"roles":[160],"control":[163],"neuroendocrine":[165],"function.":[166],"These":[167],"keywords":[168,184],"added":[170],"by":[171,175],"machine":[172],"not":[174],"authors.":[177],"This":[178],"process":[179],"is":[180],"experimental":[181],"be":[186],"updated":[187],"as":[188],"learning":[190],"algorithm":[191],"improves.":[192]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-08-23T00:00:00"}