{"id":"https://openalex.org/W2482069246","doi":"https://doi.org/10.1021/bk-1979-0094.ch001","title":"The Detection and Hazards of Environmental Carcinogens/Mutagens","display_name":"The Detection and Hazards of Environmental Carcinogens/Mutagens","publication_year":1979,"publication_date":"1979-03-13","ids":{"openalex":"https://openalex.org/W2482069246","doi":"https://doi.org/10.1021/bk-1979-0094.ch001","mag":"2482069246"},"language":"en","primary_location":{"id":"doi:10.1021/bk-1979-0094.ch001","doi":"https://doi.org/10.1021/bk-1979-0094.ch001","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bk-1979-0094.ch001","pdf_url":null,"source":{"id":"https://openalex.org/S205053445","display_name":"ACS symposium series","issn_l":"0097-6156","issn":["0097-6156","1947-5918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Symposium Series","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2483986269","display_name":"Monitoring Toxic Substances"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110195895","display_name":"Bruce N. Ames","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"BRUCE N. AMES","raw_affiliation_strings":["Biochemistry Department, University of California, Berkeley, CA 94720"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry Department, University of California, Berkeley, CA 94720","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110195895"],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":null,"apc_paid":null,"fwci":8.129,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":1.0,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11493","display_name":"Water Treatment and Disinfection","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13840","display_name":"Chemical Safety and Risk Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1504","display_name":"Chemical Health and Safety"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/environmental-carcinogens","display_name":"environmental carcinogens","score":0.996999979019165},{"id":"https://openalex.org/keywords/mutagens","display_name":"mutagens","score":0.8240000009536743},{"id":"https://openalex.org/keywords/chemical-exposure","display_name":"chemical exposure","score":0.5730000138282776},{"id":"https://openalex.org/keywords/carcinogenicity-testing","display_name":"carcinogenicity testing","score":0.8529999852180481},{"id":"https://openalex.org/keywords/mutagenicity-testing","display_name":"mutagenicity testing","score":0.9490000009536743},{"id":"https://openalex.org/keywords/commercial-chemicals","display_name":"commercial chemicals","score":0.6510000228881836},{"id":"https://openalex.org/keywords/flame-retardants","display_name":"flame retardants","score":0.7850000262260437},{"id":"https://openalex.org/keywords/pesticides","display_name":"pesticides","score":0.8619999885559082},{"id":"https://openalex.org/keywords/vinyl-chloride","display_name":"vinyl chloride","score":0.9829999804496765},{"id":"https://openalex.org/keywords/1-2-dichloroethane","display_name":"1,2-dichloroethane","score":0.9980000257492065},{"id":"https://openalex.org/keywords/human-exposure","display_name":"human exposure","score":0.5189999938011169},{"id":"https://openalex.org/keywords/hazard-assessment","display_name":"hazard assessment","score":0.4009999930858612}],"concepts":[{"id":"https://openalex.org/C114246631","wikidata":"https://www.wikidata.org/wiki/Q187661","display_name":"Carcinogen","level":2,"score":0.7839044332504272},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.6116239428520203},{"id":"https://openalex.org/C2781460079","wikidata":"https://www.wikidata.org/wiki/Q338869","display_name":"Vinyl chloride","level":4,"score":0.59574294090271},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.5210463404655457},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.43308401107788086},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3972609341144562},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.3531399369239807},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22140902280807495},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09048745036125183},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.061049431562423706},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/bk-1979-0094.ch001","doi":"https://doi.org/10.1021/bk-1979-0094.ch001","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bk-1979-0094.ch001","pdf_url":null,"source":{"id":"https://openalex.org/S205053445","display_name":"ACS symposium series","issn_l":"0097-6156","issn":["0097-6156","1947-5918"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Symposium Series","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2483986269","https://openalex.org/W166993804","https://openalex.org/W1249057804","https://openalex.org/W61113163","https://openalex.org/W2314426472","https://openalex.org/W4249269543","https://openalex.org/W4237682630","https://openalex.org/W2002546431","https://openalex.org/W3139344575","https://openalex.org/W2175472135"],"abstract_inverted_index":{"Since":[0],"the":[1,63,77,137,142,148],"1950's":[2],"we":[3],"have":[4,94],"been":[5,95],"exposed":[6],"to":[7,30],"a":[8,47,73,119],"flood":[9],"of":[10,62,121,126,140],"chemicals":[11,43,65,128],"which":[12],"were":[13],"not":[14],"tested":[15,132],"for":[16,97,136],"carcinogenicity":[17,101],"or":[18,68,102],"mutagenicity":[19,103],"before":[20],"use":[21],"\u2014":[22],"from":[23],"flame":[24],"retardants":[25],"in":[26,33,133],"our":[27,34],"children's":[28],"pajamas":[29],"pesticides":[31],"accumulating":[32],"body":[35],"fat.":[36],"There":[37],"are":[38,54,66],"now":[39,130],"about":[40],"35,000":[41],"commercial":[42],"being":[44,131],"made":[45],"on":[46],"regular":[48],"basis":[49],"and":[50,84,118],"1,000":[51],"new":[52],"ones":[53],"added":[55],"every":[56],"year.":[57],"Even":[58],"if":[59],"only":[60,143],"1%":[61],"known":[64],"mutagens":[67],"carcinogens,":[69],"this":[70,79],"could":[71],"represent":[72],"serious":[74],"problem.":[75],"In":[76],"past,":[78],"problem":[80],"was":[81],"largely":[82],"ignored,":[83],"even":[85],"very":[86],"large":[87],"volume":[88],"chemicals,":[89],"involving":[90],"extensive":[91],"human":[92],"exposure,":[93],"produced":[96],"decades":[98],"without":[99],"adequate":[100],"tests,":[104],"e.g.,":[105],"vinyl":[106],"chloride":[107],"(2.5":[108],"billion":[109,115],"kg/year,":[110,116],"U.S.),":[111,117],"ethylene":[112],"dichloride":[113],"(3.5":[114],"host":[120],"pesticides.":[122],"A":[123],"small":[124],"fraction":[125],"these":[127],"is":[129,146],"animals,":[134],"but,":[135],"vast":[138],"majority":[139],"them,":[141],"experimental":[144],"animal":[145],"still":[147],"human,":[149]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-08-23T00:00:00"}