{"id":"https://openalex.org/W2480901226","doi":"https://doi.org/10.1186/s12967-016-0947-0","title":"Visualization of atherosclerosis as detected by coronary artery calcium and carotid intima-media thickness reveals significant atherosclerosis in a cross-sectional study of psoriasis patients in a tertiary care center","display_name":"Visualization of atherosclerosis as detected by coronary artery calcium and carotid intima-media thickness reveals significant atherosclerosis in a cross-sectional study of psoriasis patients in a tertiary care center","publication_year":2016,"publication_date":"2016-07-22","ids":{"openalex":"https://openalex.org/W2480901226","doi":"https://doi.org/10.1186/s12967-016-0947-0","mag":"2480901226","pmid":"https://pubmed.ncbi.nlm.nih.gov/27448600","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4957305"},"language":"en","primary_location":{"id":"doi:10.1186/s12967-016-0947-0","doi":"https://doi.org/10.1186/s12967-016-0947-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-016-0947-0","pdf_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-016-0947-0","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-016-0947-0","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035518601","display_name":"Scott Santilli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Santilli","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058626838","display_name":"Douglas R. Kast","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. R. Kast","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019030520","display_name":"Ivan Grozdev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"I. Grozdev","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052328412","display_name":"Lauren Y. Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Cao","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055859590","display_name":"Rivka L Feig","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. L. Feig","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083856795","display_name":"Jackelyn B. Golden","orcid":"https://orcid.org/0000-0001-7844-0725","observed_orcids":["https://orcid.org/0000-0001-7844-0725"]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. B. Golden","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","Department of Pathology, Case Western Reserve University, Cleveland, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"Department of Pathology, Case Western Reserve University, Cleveland, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112154637","display_name":"S. M. Debanne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. M. Debanne","raw_affiliation_strings":["Center For Clinical Investigation, Case Western Reserve University, Cleveland, USA","Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center For Clinical Investigation, Case Western Reserve University, Cleveland, USA","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091618934","display_name":"Robert Gilkeson","orcid":"https://orcid.org/0000-0002-5931-8123","observed_orcids":["https://orcid.org/0000-0002-5931-8123"]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. C. Gilkeson","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081000352","display_name":"Carl E. Orringer","orcid":"https://orcid.org/0000-0002-1001-6781","observed_orcids":["https://orcid.org/0000-0002-1001-6781"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]},{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. E. Orringer","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA","University of Miami, Miller School of Medicine, Miami, FL, 33125, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]},{"raw_affiliation_string":"University of Miami, Miller School of Medicine, Miami, FL, 33125, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081014269","display_name":"Thomas S. McCormick","orcid":"https://orcid.org/0000-0002-3294-0326","observed_orcids":["https://orcid.org/0000-0002-3294-0326"]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"T. S. McCormick","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA. tsm4@case.edu","The Murdough Family Center for Psoriasis, Cleveland, USA. tsm4@case.edu","Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA. tsm4@case.edu","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA. tsm4@case.edu","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059212699","display_name":"Nicole L. Ward","orcid":"https://orcid.org/0000-0003-1907-2621","observed_orcids":["https://orcid.org/0000-0003-1907-2621"]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N. L. Ward","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046056281","display_name":"Kevin D. Cooper","orcid":"https://orcid.org/0000-0002-1986-3602","observed_orcids":["https://orcid.org/0000-0002-1986-3602"]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]},{"id":"https://openalex.org/I4210110978","display_name":"Louis Stokes Cleveland VA Medical Center","ror":"https://ror.org/01vrybr67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210110978","https://openalex.org/I4210127612"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. D. Cooper","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","Louis Stokes VA Medical Center, Cleveland, OH, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"Louis Stokes VA Medical Center, Cleveland, OH, USA","institution_ids":["https://openalex.org/I4210110978"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039279211","display_name":"Neil J. Korman","orcid":"https://orcid.org/0000-0002-9785-3442","observed_orcids":["https://orcid.org/0000-0002-9785-3442"]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N. J. Korman","raw_affiliation_strings":["Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","The Murdough Family Center for Psoriasis, Cleveland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University Hospitals Case Medical Center, 11000 Euclid Ave, Cleveland, OH, 44106, USA","institution_ids":["https://openalex.org/I4210108791"]},{"raw_affiliation_string":"The Murdough Family Center for Psoriasis, Cleveland, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5081014269"],"corresponding_institution_ids":["https://openalex.org/I4210108791","https://openalex.org/I58956616"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":{"value":3890,"currency":"USD","value_usd":3890},"fwci":2.591,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.89542617,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"14","issue":"1","first_page":"217","last_page":"217"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.8812999725341797,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.8812999725341797,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11092","display_name":"Spondyloarthritis Studies and Treatments","score":0.04439999908208847,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.01850000023841858,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psoriasis","display_name":"psoriasis","score":0.996999979019165},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/coronary-artery-calcium","display_name":"coronary artery calcium","score":0.925000011920929},{"id":"https://openalex.org/keywords/carotid-intima-media-thickness","display_name":"carotid intima-media thickness","score":1.0},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.7519999742507935},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/high-sensitivity-c-reactive-protein","display_name":"high-sensitivity C-reactive protein","score":0.9269999861717224},{"id":"https://openalex.org/keywords/psoriasis-severity","display_name":"psoriasis severity","score":0.6869999766349792},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.889107346534729},{"id":"https://openalex.org/C2780564577","wikidata":"https://www.wikidata.org/wiki/Q179945","display_name":"Psoriasis","level":2,"score":0.8333230018615723},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6543064713478088},{"id":"https://openalex.org/C2779339615","wikidata":"https://www.wikidata.org/wiki/Q2698596","display_name":"Intima-media thickness","level":3,"score":0.5934118628501892},{"id":"https://openalex.org/C2776252253","wikidata":"https://www.wikidata.org/wiki/Q7663815","display_name":"Systemic inflammation","level":3,"score":0.5903369188308716},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.5682008266448975},{"id":"https://openalex.org/C2991716557","wikidata":"https://www.wikidata.org/wiki/Q12252367","display_name":"Coronary atherosclerosis","level":3,"score":0.5473499298095703},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.5288116931915283},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5051668286323547},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4472624659538269},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.43402034044265747},{"id":"https://openalex.org/C2781195455","wikidata":"https://www.wikidata.org/wiki/Q422766","display_name":"C-reactive protein","level":3,"score":0.4134880304336548},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.39718902111053467},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2724892497062683},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.21661177277565002},{"id":"https://openalex.org/C2987047532","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Carotid arteries","level":2,"score":0.1510569155216217}],"mesh":[{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003710","descriptor_name":"Demography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011565","descriptor_name":"Psoriasis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D059168","descriptor_name":"Carotid Intima-Media Thickness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062606","descriptor_name":"Tertiary Care Centers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1186/s12967-016-0947-0","doi":"https://doi.org/10.1186/s12967-016-0947-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-016-0947-0","pdf_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-016-0947-0","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4957305","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4957305","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Transl Med","raw_type":"Text"},{"id":"pmid:27448600","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27448600","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of translational medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s12967-016-0947-0","doi":"https://doi.org/10.1186/s12967-016-0947-0","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12967-016-0947-0","pdf_url":"https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-016-0947-0","source":{"id":"https://openalex.org/S142026636","display_name":"Journal of Translational Medicine","issn_l":"1479-5876","issn":["1479-5876"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Translational Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1037872830","display_name":"NIAMS: CORT (Psoriasis Center of Research Translation)","funder_award_id":"P50AR055508","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G2426414387","display_name":"NIAMS Core Center: Skin Diseases Research Center","funder_award_id":"P30AR039750","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G4573897493","display_name":"Neurogenic inflammation and psoriasiform dermatitis","funder_award_id":"R21AR063852","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6942782308","display_name":"IL-17C mediated mechanisms of inflammation","funder_award_id":"R01AR062546","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G7001506527","display_name":"Remote Inflammation and Atherothrombosis","funder_award_id":"R01AR063437","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2480901226.pdf","grobid_xml":"https://content.openalex.org/works/W2480901226.grobid-xml"},"referenced_works_count":76,"referenced_works":["https://openalex.org/W92189825","https://openalex.org/W150221401","https://openalex.org/W1495040601","https://openalex.org/W1515466457","https://openalex.org/W1543621601","https://openalex.org/W1596038729","https://openalex.org/W1599017652","https://openalex.org/W1640610491","https://openalex.org/W1838120980","https://openalex.org/W1966886574","https://openalex.org/W1967934782","https://openalex.org/W1973563124","https://openalex.org/W1975162362","https://openalex.org/W1977207218","https://openalex.org/W1977265767","https://openalex.org/W1978942726","https://openalex.org/W1985055917","https://openalex.org/W1985236996","https://openalex.org/W1989425439","https://openalex.org/W1990127867","https://openalex.org/W1991510673","https://openalex.org/W1994483965","https://openalex.org/W1996866382","https://openalex.org/W1998234977","https://openalex.org/W2007557258","https://openalex.org/W2008311984","https://openalex.org/W2014286422","https://openalex.org/W2022665587","https://openalex.org/W2024387258","https://openalex.org/W2027366793","https://openalex.org/W2028621745","https://openalex.org/W2046066375","https://openalex.org/W2050608394","https://openalex.org/W2051540382","https://openalex.org/W2052383963","https://openalex.org/W2055228598","https://openalex.org/W2055326845","https://openalex.org/W2056584911","https://openalex.org/W2058610272","https://openalex.org/W2058709767","https://openalex.org/W2060887598","https://openalex.org/W2063631155","https://openalex.org/W2075936775","https://openalex.org/W2082622860","https://openalex.org/W2084023292","https://openalex.org/W2088078494","https://openalex.org/W2092809707","https://openalex.org/W2095652983","https://openalex.org/W2096209195","https://openalex.org/W2097593317","https://openalex.org/W2101806086","https://openalex.org/W2118154631","https://openalex.org/W2118617914","https://openalex.org/W2119274356","https://openalex.org/W2122865429","https://openalex.org/W2129837832","https://openalex.org/W2131341596","https://openalex.org/W2131430597","https://openalex.org/W2131836015","https://openalex.org/W2137977546","https://openalex.org/W2138492747","https://openalex.org/W2142435775","https://openalex.org/W2142919605","https://openalex.org/W2147323503","https://openalex.org/W2154960154","https://openalex.org/W2155848385","https://openalex.org/W2158723251","https://openalex.org/W2159087408","https://openalex.org/W2160222342","https://openalex.org/W2165073428","https://openalex.org/W2165577340","https://openalex.org/W2208921442","https://openalex.org/W2315575691","https://openalex.org/W2328871474","https://openalex.org/W2344145350","https://openalex.org/W4243074346"],"related_works":["https://openalex.org/W2050608394","https://openalex.org/W2125715076","https://openalex.org/W3203769806","https://openalex.org/W2139789293","https://openalex.org/W7126111500","https://openalex.org/W3027042229","https://openalex.org/W4309933599","https://openalex.org/W2067631989","https://openalex.org/W2025459598","https://openalex.org/W4416574535"],"abstract_inverted_index":{"BACKGROUND:":[0],"Psoriasis":[1,123,221,316],"is":[2],"a":[3,39,63,88,92,227,258,289,300],"chronic":[4],"inflammatory":[5,17,323],"disease":[6,24],"of":[7,22,33,49,72,91,96,136,213,219,231,285,292,306,311,329],"the":[8,20,70,180,202,304],"skin":[9],"and":[10,74,105,125,146,159,175,184,195,204,254,265,297,331],"joints":[11],"that":[12,52],"may":[13,56,317],"also":[14],"have":[15,29,226,288],"systemic":[16,54,322],"effects,":[18],"including":[19],"development":[21],"cardiovascular":[23],"(CVD).":[25],"Multiple":[26],"epidemiologic":[27],"studies":[28],"demonstrated":[30],"increased":[31,295,327],"rates":[32],"CVD":[34,330],"in":[35,58,210,326],"psoriasis":[36,59,97,183,214,266,286,298],"patients,":[37,60],"although":[38],"causal":[40],"link":[41],"has":[42],"not":[43],"been":[44],"established.":[45],"A":[46,281],"growing":[47],"body":[48],"evidence":[50],"suggests":[51],"sub-clinical":[53],"inflammation":[55],"develop":[57],"even":[61,308],"from":[62,129],"young":[64],"age.":[65],"We":[66,86],"aimed":[67],"to":[68,110,120,168,178,225,235,319],"evaluate":[69,179],"prevalence":[71,291],"atherosclerosis":[73,137,205,233,307],"identify":[75],"specific":[76],"clinical":[77,170,314],"risk":[78,301,328],"factors":[79,171],"associated":[80,172],"with":[81,114,173,191],"early":[82,293],"vascular":[83],"inflammation.":[84,122],"METHODS:":[85],"conducted":[87],"cross-sectional":[89],"study":[90],"tertiary":[93,131,282],"care":[94,132,283],"cohort":[95,284],"patients":[98,124,188,222,287],"using":[99,140,155],"coronary":[100],"artery":[101],"calcium":[102],"(CAC)":[103],"score":[104],"carotid":[106],"intima-media":[107],"thickness":[108],"(CIMT)":[109],"detect":[111],"atherosclerosis,":[112,174,294],"along":[113],"high":[115,290],"sensitivity":[116],"C-reactive":[117],"protein":[118],"(hsCRP)":[119],"measure":[121],"controls":[126,236],"were":[127,189,223],"recruited":[128],"our":[130],"dermatology":[133],"clinic.":[134],"Presence":[135],"was":[138,153,166,208,261],"defined":[139],"validated":[141],"numeric":[142],"values":[143],"within":[144],"CAC":[145],"CIMT":[147],"imaging.":[148],"Descriptive":[149],"data":[150,200],"comparing":[151],"groups":[152],"analyzed":[154],"Welch's":[156],"t":[157],"test":[158],"Pearson":[160],"Chi":[161],"square":[162],"tests.":[163],"Logistic":[164],"regression":[165,177],"used":[167],"analyze":[169],"linear":[176],"relationship":[181],"between":[182,263],"hsCRP.":[185,255],"RESULTS:":[186],"296":[187],"enrolled,":[190],"283":[192],"(207":[193],"psoriatic":[194],"76":[196],"controls)":[197],"having":[198,232],"all":[199],"for":[201,247,278,303],"hsCRP":[203],"analysis.":[206],"Atherosclerosis":[207],"found":[209,224,262],"67.6":[211],"%":[212,218,238],"subjects":[215],"versus":[216],"52.6":[217],"controls;":[220],"2.67-fold":[228],"higher":[229],"odds":[230],"compared":[234],"[95":[237],"CI":[239],"(1.2,":[240],"5.92);":[241],"p":[242],"=":[243],"0.016],":[244],"after":[245,276,309],"adjusting":[246,277],"age,":[248],"gender,":[249],"race,":[250],"BMI,":[251],"smoking,":[252],"HDL":[253],"In":[256],"addition,":[257],"non-significant":[259],"trend":[260],"HsCRP":[264],"severity,":[267],"as":[268],"measured":[269],"by":[270],"PASI,":[271],"PGA,":[272],"or":[273],"BSA,":[274],"again":[275],"confounders.":[279],"CONCLUSIONS:":[280],"hsCRP,":[296],"remains":[299],"factor":[302],"presence":[305],"adjustment":[310],"key":[312],"confounding":[313],"factors.":[315],"contribute":[318],"an":[320],"accelerated":[321],"cascade":[324],"resulting":[325],"CV":[332],"events.":[333]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-08-23T00:00:00"}
